Research output per year
Research output per year
Personal profile
Personal information
I have a background in medicinal chemistry (VU). I received my PhD at the University of Amsterdam in the field of Computational Physics & Chemistry. Since 2012 I work as assistant professor at the department of Biological Psychology. Here I work on the metabolomics data sets collected by the Netherlands Twin Register (NTR). These data comprise hundreds of metabolic variables measured in over 6000 NTR subjects. Biologically, the metabolome can be viewed as an intermediate level in the framework starting at the genome and ending at biological function, e.g. behaviour. Metabolomics can therefore be utilized to gain detailed insights in biological (dis)function. The field of metabolomics nicely brings together my interests in (bio)chemistry, in systems biology and in analyses of multi-dimensional data.
Teaching
Courses:
- Introduction to omics (RM Genes in Behaviour and Health)
- Molecular Genetics (Bachelor Psychology, third year)
Ancillary activities
No ancillary activities
Ancillary activities are updated daily
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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The association between metabolite concentrations and wellbeing in adults
Azcona-Granada, N., Geijsen, A. J. M. R., Pool, R., Pelt, D. H. M. & Bartels, M., Dec 2025, In: Scientific Reports. 15, 1, 6997.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry
Gui, A., Hollowell, A., Wigdor, E. M., Morgan, M. J., Hannigan, L. J., Corfield, E. C., Odintsova, V., Hottenga, J.-J., Wong, A., Pool, R., Cullen, H., Wilson, S., Warrier, V., Eilertsen, E. M., Andreassen, O. A., Middeldorp, C. M., St Pourcain, B., Bartels, M., Boomsma, D. I. & Hartman, C. A. & 8 others, , 7 May 2025, (E-pub ahead of print) In: Nature Human Behaviour. 8148.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Transcriptomic and Metabolomic Analyses in Monozygotic and Dizygotic Twins
Hubers, N., Drouard, G., Jansen, R., Pool, R., Hottenga, J. J., Ollikainen, M., Wang, X., Willemsen, G., Kaprio, J., Boomsma, D. I. & van Dongen, J., Apr 2025, In: American Journal of Medical Genetics, Part A. 197, 4, p. 1-12 12 p., e63971.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Blood-Based EWAS of Asthma Polygenic Burden in The Netherlands Twin Register
Van Asselt, A. J., Pool, R., Hottenga, J. J., Beck, J. J., Finnicum, C. T., Johnson, B. N., Kallsen, N., Viet, S., Huizenga, P., de Geus, E., Boomsma, D. I., Ehli, E. A. & van Dongen, J., Feb 2025, In: Biomolecules. 15, 2, p. 1-17 17 p., 251.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry
Gui, A., Hollowell, A., Wigdor, E. M., Morgan, M. J., Hannigan, L. J., Corfield, E. C., Odintsova, V., Hottenga, J. J., Wong, A., Pool, R., Cullen, H., Wilson, S., Warrier, V., Eilertsen, E. M., Andreassen, O. A., Middeldorp, C. M., St Pourcain, B., Bartels, M., Boomsma, D. I. & Hartman, C. A. & 8 others, , 2025, (Accepted/In press) In: Nature Human Behaviour. 8148.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access
Courses
Datasets
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Supplementary material 1 from: Niehues A, de Visser C, Hagenbeek FA, Karu N, Kindt ASD, Kulkarni P, Pool R, Boomsma DI, van Dongen J, van Gool AJ, `t Hoen PAC (2022) A Multi-omics Data Analysis Workflow Packaged as a FAIR Digital Object. Research Ideas and Outcomes 8: e94042. https://doi.org/10.3897/rio.8.e94042
Niehues, A. (Contributor), Hagenbeek, F. (Contributor), Karu, N. (Contributor), Kindt, A. (Contributor), Kulkarni, P. (Contributor), Pool, R. (Contributor), Boomsma, D. (Contributor), van Dongen, J. (Contributor), van Gool, A. (Contributor) & 't Hoen, P. (Contributor), Zenodo, 2022
DOI: 10.3897/rio.8.e94042.suppl1, https://zenodo.org/record/7026811
Dataset / Software: Dataset
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Data from: Large scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
Onderwater, G. L. J. (Contributor), Ligthart, L. (Contributor), Bot, M. (Contributor), Demirkan, A. (Contributor), Fu, J. (Contributor), Van Der Kallen, C. J. H. (Contributor), Vijfhuizen, L. S. (Contributor), Pool, R. (Contributor), Liu, J. (Contributor), Vanmolkot, F. H. M. (Contributor), Beekman, M. (Contributor), Amin, N. (Contributor), Thesing, C. S. (Contributor), Pijpers, J. A. (Contributor), Kies, D. A. (Contributor), Zielman, R. (Contributor), De Boer, I. (Contributor), Van Greevenbroek, M. M. J. (Contributor), Arts, I. C. W. (Contributor), Milaneschi, Y. (Contributor), Schram, M. T. (Contributor), Dagnelie, P. C. (Contributor), Franke, L. (Contributor), Ikram, M. A. (Contributor), Ferrari, M. D. (Contributor), Goeman, J. J. (Contributor), Slagboom, P. E. (Contributor), Wijmenga, C. (Contributor), Stehouwer, C. D. A. (Contributor), Boomsma, D. I. (Contributor), Van Duijn, C. M. (Contributor), Penninx, B. W. (Contributor), Terwindt, G. M. (Contributor) & Van Den Maagdenberg, A. M. J. M. (Contributor), Zenodo, 2019
DOI: 10.5061/dryad.p698mn7, https://zenodo.org/record/4977081
Dataset / Software: Dataset
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Data from: Large scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
Onderwater, G. L. J. (Contributor), Ligthart, L. (Contributor), Bot, M. (Contributor), Demirkan, A. (Contributor), Fu, J. (Contributor), Van Der Kallen, C. J. H. (Contributor), Vijfhuizen, L. S. (Contributor), Pool, R. (Contributor), Liu, J. (Contributor), Vanmolkot, F. H. M. (Contributor), Beekman, M. (Contributor), Wen, H. (Contributor), Amin, N. (Contributor), Thesing, C. S. (Contributor), Pijpers, J. A. (Contributor), Kies, D. A. (Contributor), Zielman, R. (Contributor), De Boer, I. (Contributor), Van Greevenbroek, M. M. J. (Contributor), Arts, I. C. W. (Contributor), Milaneschi, Y. (Contributor), Schram, M. T. (Contributor), Dagnelie, P. C. (Contributor), Franke, L. (Contributor), Ikram, M. A. (Contributor), Ferrari, M. D. (Contributor), Goeman, J. J. (Contributor), Slagboom, P. E. (Contributor), Wijmenga, C. (Contributor), Stehouwer, C. D. A. (Contributor), Boomsma, D. I. (Contributor), Van Duijn, C. M. (Contributor), Penninx, B. W. (Contributor), ’T Hoen, P. A. C. (Contributor), Terwindt, G. M. (Contributor) & Van Den Maagdenberg, A. M. J. M. (Contributor), Unknown Publisher, 1 Jan 2019
DOI: 10.5061/dryad.p698mn7, http://datadryad.org/stash/dataset/doi:10.5061/dryad.p698mn7
Dataset / Software: Dataset
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ENGAGE Biocrates GWA meta analyses - data
Pool, R. (Contributor), Unknown Publisher, 1 Jan 2020
DOI: 10.34894/jfwws4, https://doi.org/10.34894%2Fjfwws4
Dataset / Software: Dataset