• De Boelelaan 1085, kamernummer B431, W&N

    1081HV Amsterdam

20112019
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Research

Fingerprint Dive into the research topics where Rik van der Kant is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Exosomes Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Cholesterol Esters Medicine & Life Sciences
Endosomes Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Cholesterol Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Membrane Proteins Medicine & Life Sciences

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Research Output 2011 2019

Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons

van der Kant, R., Langness, V. F., Herrera, C. M., Williams, D. A., Fong, L. K., Leestemaker, Y., Steenvoorden, E., Rynearson, K. D., Brouwers, J. F., Helms, J. B., Ovaa, H., Giera, M., Wagner, S. L., Bang, A. G. & Goldstein, L. S. B., 7 Mar 2019, In : Cell Stem Cell. 24, 3, p. 363-375.e9

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Induced Pluripotent Stem Cells
Cholesterol Esters
Amyloid
Alzheimer Disease
Cholesterol

LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation

Verweij, F. J., Van Eijndhoven, M. A. J., Hopmans, E. S., Vendrig, T., Wurdinger, T., Cahir-Mcfarland, E., Kieff, E., Geerts, D., Van Der Kant, R., Neefjes, J., Middeldorp, J. M. & Pegtel, D. M., 1 Jun 2011, In : EMBO Journal. 30, 11, p. 2115-2129 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Exosomes
Endosomes
Membrane Proteins
Chemical activation
Association reactions