Research Output per year
Personal profile
Fingerprint Dive into the research topics where Rik van der Kant is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Endosomes
Medicine & Life Sciences
Cholesterol
Medicine & Life Sciences
Dyneins
Medicine & Life Sciences
Alzheimer Disease
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Neuronal Ceroid-Lipofuscinoses
Medicine & Life Sciences
Exosomes
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2009 2019
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons
van der Kant, R., Langness, V. F., Herrera, C. M., Williams, D. A., Fong, L. K., Leestemaker, Y., Steenvoorden, E., Rynearson, K. D., Brouwers, J. F., Helms, J. B., Ovaa, H., Giera, M., Wagner, S. L., Bang, A. G. & Goldstein, L. S. B., 7 Mar 2019, In : Cell Stem Cell. 24, 3, p. 363-375.e9Research output: Contribution to Journal › Article › Academic › peer-review
Open Access
Induced Pluripotent Stem Cells
Cholesterol Esters
Amyloid
Alzheimer Disease
Cholesterol
Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations
Woodruff, G., Reyna, S. M., Dunlap, M., Van Der Kant, R., Callender, J. A., Young, J. E., Roberts, E. A. & Goldstein, L. S. B., 11 Oct 2016, In : Cell Reports. 17, 3, p. 759-773 15 p.Research output: Contribution to Journal › Article › Academic › peer-review
Transcytosis
Lipoproteins
Neurons
Alzheimer Disease
Endocytosis
Cellular functions of the amyloid precursor protein from development to dementia
van der Kant, R. & Goldstein, L. S. B., 23 Feb 2015, In : Dev Cell. 32, 4, p. 502-15 14 p.Research output: Contribution to Journal › Review article › Academic › peer-review
Amyloid beta-Protein Precursor
Dementia
Alzheimer Disease
Serum Amyloid A Protein
Gene Duplication
Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity
van der Kant, R., Jonker, C. T. H., Wijdeven, R. H., Bakker, J., Janssen, L., Klumperman, J. & Neefjes, J., 18 Dec 2015, In : Journal of Biological Chemistry. 290, 51, p. 30280-90 11 p.Research output: Contribution to Journal › Article › Academic › peer-review
Endosomes
Yeast
Yeasts
Fusion reactions
rab GTP-Binding Proteins
GPR43 Potentiates β-Cell Function in Obesity
McNelis, J. C., Lee, Y. S., Mayoral, R., van der Kant, R., Johnson, A. M. F., Wollam, J. & Olefsky, J. M., Sep 2015, In : Diabetes. 64, 9, p. 3203-17 15 p.Research output: Contribution to Journal › Article › Academic › peer-review
High Fat Diet
Volatile Fatty Acids
Obesity
Knockout Mice
Insulin