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Fingerprint Dive into the research topics where R.V. Klaassen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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AMPA Receptors Medicine & Life Sciences
Proteins Medicine & Life Sciences
Serotonin Medicine & Life Sciences
Hippocampus Medicine & Life Sciences
Carrier Proteins Medicine & Life Sciences
Bulinus Medicine & Life Sciences
Acetylcholine Medicine & Life Sciences
Ligand-Gated Ion Channels Medicine & Life Sciences

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Research Output 2001 2017

The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory

Schmitz, L. J. M., Klaassen, R. V., Ruiperez-Alonso, M., Zamri, A. E., Stroeder, J., Rao-Ruiz, P., Lodder, J. C., van der Loo, R. J., Mansvelder, H. D., Smit, A. B. & Spijker, S., 4 Dec 2017, In : eLife. 6, p. 1-28 28 p., e24192.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
AMPA Receptors
Data storage equipment
Synapses
Proteins
Neuronal Plasticity

Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex

Pandya, N. J., Klaassen, R. V., van der Schors, R. C., Slotman, J. A., Houtsmuller, A., Smit, A. B. & Li, K. W., 2016, In : Proteomics. 16, 20, p. 2698-2705 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Hippocampus
Proteins
Metabotropic Glutamate 5 Receptor
Neuronal Plasticity
HEK293 Cells

Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity.

Klaassen, R. V., Stroeder, J., Coussen, F., Hafner, A. S., Petersen, J. D., Renancio, C., Schmitz, L. J., Normand, E., Lodder, J. C., Rotaru-Marcu, D. C., Rao-Ruiz, P., Spijker, S., Mansvelder, H. D., Choquet, D. & Smit, A. B., 2016, In : Nature Communications. 7, 1, 10682.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences

Giniatullina, A., Maroteaux, G. P., Geerts, C. J., Koopmans, B., Loos, M., Klaassen, R. V., Chen, N., van der Schors, R. C., van Nierop, P., Li, K. W., de Jong, A. P. H., Altrock, W. D., Cornelisse, L. N., Toonen, R. F. G., van der Sluis, S., Sullivan, P. F., Stiedl, O., Posthuma, D., Smit, A. B., Groffen, A. J. A. & 1 othersVerhage, M., 2015, In : Neuroscience. 300, p. 518-538

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Phenotype
Calcium
Genetic Heterogeneity
Synaptic Vesicles

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes

Chen, N., Koopmans, F. T. W., Gordon, A., Paliukhovich, I., Klaassen, R. V., van der Schors, R. C., Peles, E., Verhage, M., Smit, A. B. & Li, K. W., 2015, In : Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1854, 7, p. 827-833

Research output: Contribution to JournalArticleAcademicpeer-review

Autistic Disorder
Proteomics
Protein Isoforms
Contactins
Post-Synaptic Density