Research output per year
Research output per year
Personal profile
Personal information
Associate Professor of Structural Chemical Biology
Head of Structure Determination
Vrije Universiteit Amsterdam
Netherlands
website: www.SvensLab.com
Ancillary activities
- Smidgentec B. V. | Amsterdam | Partner | 2019-06-18 - present
- Incircular B. V. | Amsterdam | Adviseur | 2021-02-10 - present
- Nederlandse Vereniging voor Kristallografie - NVK | Amsterdam | Bestuurder | 2021-03-05 - present
Ancillary activities are updated daily
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
User created Keywords
- INCYPRO
- incircular
- protein stabilization
- enzyme stabilization
- X-Ray
- protein crystallography
- structural chemical biology
- cryoEM
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Structure-Based Design of Bicyclic Helical Peptides That Target the Oncogene β-Catenin
Yeste-Vázquez, A., Paulussen, F. M., Wendt, M., Klintrot, R., Schulte, C., Wallraven, K., van Gijzel, L., Simeonov, B., van der Gaag, M., Gerber, A., Maric, H. M., Hennig, S. & Grossmann, T. N., 18 Nov 2024, In: Angewandte Chemie. International Edition. 63, 47, p. 1-8 9 p., e202411749.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Binding dynamics of a stapled peptide targeting the transcription factor NF-Y
Durukan, C., Arbore, F., Klintrot, R., Bigiotti, C., Ilie, I. M., Vreede, J., Grossmann, T. N. & Hennig, S., 2 May 2024, In: ChemBioChem. 25, 9, p. 1-9 9 p., e202400020.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Covalent bicyclization of protein complexes yields durable quaternary structures
Hutchins, G. H., Kiehstaller, S., Poc, P., Lewis, A. H., Oh, J., Sadighi, R., Pearce, N. M., Ibrahim, M., Drienovská, I., Rijs, A. M., Neubacher, S., Hennig, S. & Grossmann, T. N., Feb 2024, In: Chem. 10, 2, p. 615-627 14 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Environment-Responsive Peptide Dimers Bind and Stabilize Double-Stranded RNA
McLoughlin, N. M., Albers, M. A., Collado Camps, E., Paulus, J., Ran, Y. A., Neubacher, S., Hennig, S., Brock, R. & Grossmann, T. N., 9 Oct 2023, In: Angewandte Chemie. International Edition. 62, 41, 7 p., e202308028.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Multicomponent Synthesis of the SARS-CoV-2 Main Protease Inhibitor Nirmatrelvir
Preschel, H. D., Otte, R. T., Zhuo, Y., Ruscoe, R. E., Burke, A. J., Kellerhals, R., Horst, B., Hennig, S., Janssen, E., Green, A. P., Turner, N. J. & Ruijter, E., 1 Sept 2023, In: The Journal of organic chemistry. 88, 17, p. 12565-12571 7 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access
Courses
Prizes / Grants
Datasets
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CCDC 2180883: Experimental Crystal Structure Determination
Horst, B. (Contributor), Verdoorn, D. S. (Contributor), Hennig, S. (Contributor), van der Heijden, G. (Contributor) & Ruijter, E. (Contributor), Cambridge Crystallographic Data Centre, 2022
DOI: 10.5517/ccdc.csd.cc2c6d22, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc2c6d22&sid=DataCite
Dataset / Software: Dataset