Tom Grossmann

Professor of Organic Chemistry

Vrije Universiteit Amsterdam

The Netherlands

website: www.grossmannlab.com

Short CV

Since 2016 - Full Professor, Vrije Universiteit Amsterdam, The Netherlands

2011-2015 - Group leader, Chemical Genomics Centra and Technical University Dortmund, Germany

2008-2011 - Postdoctoral research with Gregory L. Verdine, Harvard University, USA

2004-2008 - PhD research with Oliver Seitz, Humboldt-Universität zu Berlin, Germany

2003-2004 - Diploma research with K. Peter C. Vollhardt, University of California, Berkeley, USA

1999-2003 - Chemistry studies, Humboldt-Universität zu Berlin, Germany

Additional Information

Since Jun 2016 - Editorial board member of Scientific Reports (Category: Chemical Biology)

Since Sep 2008 - Member of Friends and Supporters of the Young Chemists' Forum

Since Oct 1999 - Member of the German Chemical Society (GDCh)

Major Recent Funding Schemes

• Chemical Genomics Centre of the Max Planck Society
• Emmy Noether Programme by the German research foundation
• ERC Starting Grant by the European Research Council

Research Highlights

• Cell Chem. Biol. 2017, 24, 958-968: Cell Permeable Stapled Peptide Inhibitor of Wnt Signaling that Targets β-Catenin Protein-Protein Interactions
  
• Nature Commun. 2016, 7, 11300: Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides (collaboration with Fürster and Waldmann lab)
• Angew. Chem. Int. Ed. 2015, 54, 8896-8927: Structure-based design of inhibitors of protein-protein interactions: Mimicking peptide binding epitopes (review)
• Angew. Chem. Int. Ed. 2015, 54, 13796-13800: Redox modulation of PTEN phosphatase activity by hydrogen peroxide and bisperoxidovanadium complexes
• Angew. Chem. Int. Ed. 2014, 53, 4337-4340: Protein-templated peptide ligation
• Angew. Chem. Int. Ed. 2014, 53, 2489-2503: Constrained peptides with target-adapted crosslinks as inhibitors of a pathogenic protein-protein interacton

19 Feb 2016 - Student teaching award by the Chemistry and Chemical Biology Student Council, Technical University Dortmund, Germany

01 Jan 2014 - Thieme Chemistry Journal Award 2014

05 Dec 2013 - Winner of the ideas competition "Arthrose - muss das sein?" by the German Rheumatology Association (with Dr. Jessica Bertrand)

4 Dec 2009 - Schering Ph.D. award 2008, joint award of Berlin's three universities honoring the best Ph.D. thesis in chemistry

10 Dec 2008 - Fischer-Nernst Ph.D. award 2008 from the Department of Chemistry at the Humboldt-Universität zu Berlin honoring the best Ph.D. thesis

19 Oct 2005 - Fischer-Nernst study award 205 from the Department of Chemistry at the Humboldt-Universität zu Berlin, Germany

• Max Planck Society | Dortmund | consultant | 2018-01-03
• Merck | Darmstadt | consultant | 2018-01-03

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