Research output per year
Research output per year
Personal profile
Personal information
Vidya Chandrasekaran received integrated Master’s degree in Industrial Biotechnology from SASTRA University, India in 2015. For her Master’s thesis, Vidya worked in the Laboratory of Kidney Toxicology and Regeneration, Brigham and Women’s Hospital, Boston, towards understanding the pathophysiology of kidney disease. She also had a yearlong experience in developing a cell-based bioassay for identifying predictive toxicity signatures at the Laboratory of System Pharmacology, Harvard Medical School, Boston. To advance her scientific knowledge in the field of invitro toxicology, she joined in3 project through Prof. Dr. Paul Jennings’s lab at the Division of Molecular and Computational Toxicology, Vrije Universiteit, Amsterdam.
Research
As a part of the in3 project, Vidya is focused mainly on the differentiation of renal proximal tubule-like cells from induced pluripotent stem cells (iPSCs) and application to nephrotoxicity testing.
Ancillary activities
No ancillary activities
Ancillary activities are updated daily
Academic qualification
Industrial Biotechnology, Master, SASTRA University
2010 → 2015
Keywords
- R Medicine
- stem cells
- iPSC
- renal
- Q Science
- Toxicology
- invitro
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Collaborations and top research areas from the last five years
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Research output
- 5 Article
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Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures
Chandrasekaran, V., Wellens, S., Bourguignon, A., Djidrovski, I., Fransen, L., Ghosh, S., Mazidi, Z., Murphy, C., Nunes, C., Singh, P., Zana, M., Armstrong, L., Dinnyés, A., Grillari, J., Grillari-Voglauer, R., Leonard, M. O., Verfaillie, C., Wilmes, A., Zurich, M. G. & Exner, T. & 2 others, , Jun 2024, In: Toxicology in Vitro. 98, p. 1-12 12 p., 105826.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat
Nunes, C., Singh, P., Mazidi, Z., Murphy, C., Bourguignon, A., Wellens, S., Chandrasekaran, V., Ghosh, S., Zana, M., Pamies, D., Thomas, A., Verfaillie, C., Culot, M., Dinnyes, A., Hardy, B., Wilmes, A., Jennings, P., Grillari, R., Grillari, J. & Zurich, M.-G. & 1 others, , Jun 2022, In: Toxicology in Vitro. 81, p. 1-16 16 p., 105333.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability
Chandrasekaran, V., Carta, G., da Costa Pereira, D., Gupta, R., Murphy, C., Feifel, E., Kern, G., Lechner, J., Cavallo, A. L., Gupta, S., Caiment, F., Kleinjans, J. C. S., Gstraunthaler, G., Jennings, P. & Wilmes, A., Dec 2021, In: Scientific Reports. 11, p. 1-17 17 p., 11575.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Temporal transcriptomic alterations of cadmium exposed human iPSC-derived renal proximal tubule-like cells
Singh, P., Chandrasekaran, V., Hardy, B., Wilmes, A., Jennings, P. & Exner, T. E., Oct 2021, In: Toxicology in Vitro. 76, p. 1-13 13 p., 105229.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Evaluation of a human iPSC-derived BBB model for repeated dose toxicity testing with cyclosporine A as model compound
Wellens, S., Dehouck, L., Chandrasekaran, V., Singh, P., Loiola, R. A., Sevin, E., Exner, T., Jennings, P., Gosselet, F. & Culot, M., Jun 2021, In: Toxicology in Vitro. 73, 105112.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access