TY - JOUR
T1 - 1-Azadienes in cycloaddition and multicomponent reactions towards N-heterocycles
AU - Groenendaal, B.
AU - Ruijter, E.
AU - Orru, R.V.A.
PY - 2008
Y1 - 2008
N2 - 1-Azadienes are versatile building blocks for the efficient construction of various N-heterocycles. Depending on the substitution pattern and reaction partner, they may participate in a range of different reactions. An overview of recent methods for the generation of 1-azadienes is presented, as well as their application in cycloaddition, electrocyclization, and multicomponent reactions. Considering the broad range of reactivities and resulting heterocyclic scaffold structures, 1-azadienes are very useful reactive intermediates for the development of modular reaction sequences in diversity-oriented synthesis. © The Royal Society of Chemistry.
AB - 1-Azadienes are versatile building blocks for the efficient construction of various N-heterocycles. Depending on the substitution pattern and reaction partner, they may participate in a range of different reactions. An overview of recent methods for the generation of 1-azadienes is presented, as well as their application in cycloaddition, electrocyclization, and multicomponent reactions. Considering the broad range of reactivities and resulting heterocyclic scaffold structures, 1-azadienes are very useful reactive intermediates for the development of modular reaction sequences in diversity-oriented synthesis. © The Royal Society of Chemistry.
UR - https://www.scopus.com/pages/publications/55849150974
UR - https://www.scopus.com/inward/citedby.url?scp=55849150974&partnerID=8YFLogxK
U2 - 10.1039/b809206k
DO - 10.1039/b809206k
M3 - Article
SN - 1359-7345
SP - 5474
EP - 5489
JO - Chemical Commununications
JF - Chemical Commununications
IS - 43
ER -