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10kin1day: A bottom-up neuroimaging initiative

  • Martijn P. Van Den Heuvel*
  • , Lianne H. Scholtens
  • , Hannelore K. Van Der Burgh
  • , Federica Agosta
  • , Clara Alloza
  • , Celso Arango
  • , Bonnie Auyeung
  • , Simon Baron-Cohen
  • , Silvia Basaia
  • , Manon J.N.L. Benders
  • , Frauke Beyer
  • , Linda Booij
  • , Kees P.J. Braun
  • , Geraldo Busatto Filho
  • , Wiepke Cahn
  • , Dara M. Cannon
  • , Tiffany M. Chaim-Avancini
  • , Sandra S.M. Chan
  • , Eric Y.H. Chen
  • , Benedicto Crespo-Facorro
  • Eveline A. Crone, Udo Dannlowski, Sonja M.C. De Zwarte, Bruno Dietsche, Gary Donohoe, Stefan Du Plessis, Sarah Durston, Covadonga M. Díaz-Caneja, Ana M. Díaz-Zuluaga, Robin Emsley, Massimo Filippi, Thomas Frodl, Martin Gorges, Beata Graff, Dominik Grotegerd, Dariusz Gąsecki, Julie M. Hall, Laurena Holleran, Rosemary Holt, Helene J. Hopman, Andreas Jansen, Joost Janssen, Krzysztof Jodzio, Lutz Jäncke, Vasiliy G. Kaleda, Jan Kassubek, Shahrzad Kharabian Masouleh, Tilo Kircher, Martijn G.J.C. Koevoets, Vladimir S. Kostic, Axel Krug, Stephen M. Lawrie, Irina S. Lebedeva, Edwin H.M. Lee, Tristram A. Lett, Simon J.G. Lewis, Franziskus Liem, Michael V. Lombardo, Carlos Lopez-Jaramillo, Daniel S. Margulies, Sebastian Markett, Paulo Marques, Ignacio Martínez-Zalacaín, Colm McDonald, Andrew M. McIntosh, Genevieve McPhilemy, Susanne L. Meinert, José M. Menchón, Christian Montag, Pedro S. Moreira, Pedro Morgado, David O. Mothersill, Susan Mérillat, Hans Peter Müller, Leila Nabulsi, Pablo Najt, Krzysztof Narkiewicz, Patrycja Naumczyk, Bob Oranje, Victor Ortiz Garcia De la Foz, Jiska S. Peper, Julian A. Pineda, Paul E. Rasser, Ronny Redlich, Jonathan Repple, Martin Reuter, Pedro G.P. Rosa, Amber N.V. Ruigrok, Agnieszka Sabisz, Ulrich Schall, Soraya Seedat, Mauricio H. Serpa, Stavros Skouras, Carles Soriano-Mas, Nuno Sousa, Edyta Szurowska, Alexander S. Tomyshev, Diana Tordesillas-Gutierrez, Sofie L. Valk, Leonard H. Van Den Berg, Theo G.M. Van Erp, Neeltje E.M. Van Haren, Judith M.C. Van Leeuwen, Arno Villringer, Christiaan H. Vinkers, Christian Vollmar, Lea Waller, Henrik Walter, Heather C. Whalley, Marta Witkowska, A. Veronica Witte, Marcus V. Zanetti, Rui Zhang, Siemon C. De Lange
*Corresponding author for this work

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

We organized 10Kin1day, a pop-up scientific event with the goal to bring together neuroimaging groups from around the world to jointly analyze 10,000+ existing MRI connectivity datasets during a 3-day workshop. In this report, we describe the motivation and principles of 10Kin1day, together with a public release of 8,000+ MRI connectome maps of the human brain. Ongoing grand-scale projects like the European Human Brain Project (1), the US Brain Initiative (2), the Human Connectome Project (3), the Chinese Brainnetome (4) and exciting world-wide neuroimaging collaborations such as ENIGMA (5) herald the new era of big neuroscience. In conjunction with these major undertakings, there is an emerging trend for bottom-up initiatives, starting with small-scale projects built upon existing collaborations and infrastructures. As described by Mainen et al. (6), these initiatives are centralized around self-organized groups of researchers working on the same challenges and sharing interests and specialized expertise. These projects could scale and open up to a larger audience and other disciplines over time, eventually lining up and merging their findings with other programs to make the bigger picture.

Original languageEnglish
Article number425
Pages (from-to)1-7
Number of pages7
JournalFrontiers in Neurology
Volume10
Issue numberMAY
DOIs
Publication statusPublished - 9 May 2019

Funding

We further like to thank Joanna Goc, Veronica O’Keane, Devon Shook, and Leonardo Tozzi for their participation and/or support of the 10K project. HCP data was provided by the Human Connectome Project, WU-Minn Consortium (Principal Investigators: David Van Essen and Kamil Ugurbil; 1U54MH091657) funded by the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University. The 10Kin1day workshop was generously sponsored by the Neuroscience and Cognition program Utrecht (NCU) of the Utrecht University (https://www.uu.nl/en/research/ neuroscience-and-cognition-utrecht), the ENIGMA consortium (http://enigma.ini.usc.edu), and personal grants: MvdH: NWO-VIDI (452-16-015), MQ Fellowship; SB-C: the Wellcome Trust; Medical Research Council UK; NIHR CLAHRC for Cambridgeshire and Peterborough Foundation National Health Services Trust; Autism Research Trust; LB: New Investigator Award, Canadian Institutes of Health Research; Dara Cannon: Health Research Board (HRB), Ireland (grant code HRA-POR-2013-324); SC: Research Grant Council (Hong Kong)-GRF 14101714; Eveline Crone: ERC-2010-StG-263234; UD: DFG, grant FOR2107 DA1151/5-1, DA1151/5-2, SFB-TRR58, Project C09, IZKF, grant Dan3/012/17; SD: MRC-RFA-UFSP-01-2013 (Shared Roots MRC Flagship grant); TF: Marie Curie Programme, International Training Programme, r’Birth; DG: National Science Centre (UMO-2011/02/A/NZ5/00329); BG: National Science Centre (UMO-2011/02/A/NZ5/00329); JH: Western Sydney University Postgraduate Research Award; LH: Science Foundation Ireland, ERC; HH: Research Grant Council (Hong Kong)-GRF 14101714; LJ: Velux Stiftung, grant 369 & UZH University Research Priority Program Dynamics of Healthy Aging; AJ: DFG, grant FOR2107 JA 1890/7-1; KJ: National Science Centre (UMO-2013/09/N/HS6/02634); VK: The Russian Foundation for Basic Research (grant code 15-06-05758 A); TK: DFG, grant FOR2107 KI 588/14-1, DFG, grant FOR2107 KI 588/15-1; AK: DFG, grant FOR2107 KO 4291/4-1, DFG, grant FOR2107 KO 4291/3-1; IL: The Russian Foundation for Basic Research (grant code 15-06-05758 A); EL: Health and Medical Research Fund - 11121271; SiL: NHMRC-ARC Dementia Fellowship 1110414, NHMRC Dementia Research Team Grant 1095127, NHMRC Project Grant 1062319; CL-J: 537-2011, 2014-849; AM: Wellcome Trust Strategic Award (104036/Z/14/Z), MRC Grant MC_PC_17209; CM: Heisenberg-Grant, German Research Foundation, DFG MO 2363/3-2; PM: Foundation for Science and Technology, Portugal - PDE/BDE/113601/2015; KN: National Science Centre (UMO-2011/02/A/NZ5/00329); PN: National Science Centre (UMO-2013/09/N/HS6/02634); JiP: NWO-Veni 451-10-007; PaR: PER and US would like to thank the Schizophrenia Research Institute and the Chief-Investigators of the Australian Schizophrenia Research Bank V. Carr, U. Schall, R. Scott, A. Jablensky, B. Mowry, P. Michie, S. Catts, F. Henskens, and C. Pantelis; AS: National Science Centre (UMO-2011/02/A/NZ5/00329); SS: European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 707730; CS-M: Carlos III Health Institute (PI13/01958), Carlos III Health Institute (PI16/00889), Carlos III Health Institute (CPII16/00048); ES: National Science Centre (UMO-2011/02/A/NZ5/00329); AT: The Russian Foundation for Basic Research (grant code 15-06-05758 A); DT-G: PI14/00918, PI14/00639; Leonardo Tozzi: Marie Curie Programme, International Training Programme, r’Birth; SV: IMPRS Neurocom stipend; TvE: National Center for Research Resources at the National Institutes of Health (grant numbers: NIH 1 U24 RR021992 (Function Biomedical Informatics Research Network), NIH 1 U24 RR025736-01 (Biomedical Informatics Research Network Coordinating Center; http://www.birncommunity.org) and the NIH Big Data to Knowledge (BD2K) award (U54 EB020403 to Paul Thompson). NvH: NWO-VIDI (452-11-014); MW: National Science Centre (UMO-2011/02/A/NZ5/00329); Veronica O’Keane: Meath Foundation; AV and AW: CRC Obesity Mechanism (SFB 1052) Project A1 funded by DFG. The funding sources had no role in the study design, data collection, analysis, and interpretation of the data.

FundersFunder number
NIH Blueprint for Neuroscience Research
Seventh Framework Programme
NHMRC-ARC
Autism Research Trust
Cambridgeshire and Peterborough Foundation National Health Services Trust
Horizon 2020 Framework Programme
Neuroscience and Cognition program Utrecht
Schizophrenia Research Institute
Science Foundation Ireland
University of Western Sydney
Universiteit Utrecht
International Max Planck Research School for Advanced Methods in Process and Systems Engineering
Collaboration for Leadership in Applied Health Research and Care - Greater Manchester
Canadian Institutes of Health Research
MRC-RFA-UFSP-01-2013
Meath Foundation
McDonnell Center for Systems Neuroscience
National Institutes of HealthNIH 1 U24 RR021992, U54 EB020403, 452-11-014, 1 U24 RR025736-01
H2020 Marie Skłodowska-Curie Actions707730
NWO-VIDI452-16-015
Medical Research CouncilDFG MO 2363/3-2, MC_PC_17209
Velux Stiftung369
Narodowe Centrum NaukiUMO-2011/02/A/NZ5/00329
Research Grants Council, University Grants CommitteeDA1151/5-2, SFB-TRR58, FOR2107 DA1151/5-1, ERC-2010-StG-263234, GRF 14101714
Fundação para a Ciência e a TecnologiaPDE/BDE/113601/2015
Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum WürzburgDan3/012/17
NWO-VENI451-10-007
UZH UniversityFOR2107 JA 1890/7-1, UMO-2013/09/N/HS6/02634
Health and Medical Research Fund11121271
Wellcome Trust104036
National Health and Medical Research Council104036/Z/14/Z, 2014-849, 1062319, 1095127, 1110414
Russian Foundation for Basic ResearchFOR2107 KO 4291/4-1, FOR2107 KO 4291/3-1, FOR2107 KI 588/15-1, FOR2107 KI 588/14-1, 15-06-05758 A
CRC Obesity MechanismSFB 1052
Instituto de Salud Carlos IIICPII16/00048, PI16/00889, PI14/00639, PI13/01958, PI14/00918
European Commission263234
Health Research BoardHRA-POR-2013-324

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 17 - Partnerships for the Goals
      SDG 17 Partnerships for the Goals

    Keywords

    • Brain
    • Connectome analysis
    • Diffusion weighted MRI
    • MRI
    • Network

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