Abstract
Until now no urinary biomarker of exposure was available to assess human exposure to epichlorohydrin (ECH). For this purpose the urinary excretion of mercapturic acids and α-chlorohydrin (α-CH), which are potential metabolites of ECH in humans was investigated. This study was undertaken in a chemical plant in which ECH is used in the production of glycidyl ethers. Urine samples were collected from 19 persons at the beginning and at the end of work-shifts and at the morning after the last work-shift. Respiratory air concentrations of ECH were determined by personal air monitoring (PAM) and were found to range from < 0.03 to 1.1 mg/m
Original language | English |
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Pages (from-to) | 175-185 |
Journal | Environmental Toxicology and Pharmacology |
Volume | 3 |
DOIs | |
Publication status | Published - 1997 |