3-Substituted Xanthines as Promising Candidates for Quadruplex Formation: Computational, Synthetic and Analytical Studies

J. Szolomájer, G. Paragi, G. Batta, C. Fonseca Guerra, F.M. Bickelhaupt, Z. Kele, P. Pádár, Z. Zupihára, L. Kovács

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Our computational studies suggest that 3-substituted xanthines are good candidates for tetrad and quadruplex structures. 3-Methylxanthine (3MX) has been synthesized from 7-benzylxanthine, and the existence of tetrameric and octameric aggregates of 3MX with NH
Original languageEnglish
Pages (from-to)476-482
JournalNew Journal of Chemistry
Volume35
DOIs
Publication statusPublished - 2011

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