3-Substituted Xanthines as Promising Candidates for Quadruplex Formation: Computational, Synthetic and Analytical Studies

J. Szolomájer; G. Paragi; G. Batta; C. Fonseca Guerra; F.M. Bickelhaupt; Z. Kele; P. Pádár; Z. Zupihára; L. Kovács

doi:10.1039/c0nj00612b

3-Substituted Xanthines as Promising Candidates for Quadruplex Formation: Computational, Synthetic and Analytical Studies

J. Szolomájer
, G. Paragi
, G. Batta
, C. Fonseca Guerra
, F.M. Bickelhaupt
, Z. Kele
, P. Pádár
, Z. Zupihára
, L. Kovács

AIMMS

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Our computational studies suggest that 3-substituted xanthines are good candidates for tetrad and quadruplex structures. 3-Methylxanthine (3MX) has been synthesized from 7-benzylxanthine, and the existence of tetrameric and octameric aggregates of 3MX with NH

Original language	English
Pages (from-to)	476-482
Journal	New Journal of Chemistry
Volume	35
DOIs	https://doi.org/10.1039/c0nj00612b
Publication status	Published - 2011

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title = "3-Substituted Xanthines as Promising Candidates for Quadruplex Formation: Computational, Synthetic and Analytical Studies",

abstract = "Our computational studies suggest that 3-substituted xanthines are good candidates for tetrad and quadruplex structures. 3-Methylxanthine (3MX) has been synthesized from 7-benzylxanthine, and the existence of tetrameric and octameric aggregates of 3MX with NH",

author = "J. Szolom{\'a}jer and G. Paragi and G. Batta and \{Fonseca Guerra\}, C. and F.M. Bickelhaupt and Z. Kele and P. P{\'a}d{\'a}r and Z. Zupih{\'a}ra and L. Kov{\'a}cs",

year = "2011",

doi = "10.1039/c0nj00612b",

language = "English",

volume = "35",

pages = "476--482",

journal = "New Journal of Chemistry",

issn = "1144-0546",

publisher = "Royal Society of Chemistry",

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T1 - 3-Substituted Xanthines as Promising Candidates for Quadruplex Formation: Computational, Synthetic and Analytical Studies

AU - Szolomájer, J.

AU - Paragi, G.

AU - Batta, G.

AU - Fonseca Guerra, C.

AU - Bickelhaupt, F.M.

AU - Kele, Z.

AU - Pádár, P.

AU - Zupihára, Z.

AU - Kovács, L.

PY - 2011

Y1 - 2011

N2 - Our computational studies suggest that 3-substituted xanthines are good candidates for tetrad and quadruplex structures. 3-Methylxanthine (3MX) has been synthesized from 7-benzylxanthine, and the existence of tetrameric and octameric aggregates of 3MX with NH

AB - Our computational studies suggest that 3-substituted xanthines are good candidates for tetrad and quadruplex structures. 3-Methylxanthine (3MX) has been synthesized from 7-benzylxanthine, and the existence of tetrameric and octameric aggregates of 3MX with NH

U2 - 10.1039/c0nj00612b

DO - 10.1039/c0nj00612b

M3 - Article

SN - 1144-0546

VL - 35

SP - 476

EP - 482

JO - New Journal of Chemistry

JF - New Journal of Chemistry

ER -

3-Substituted Xanthines as Promising Candidates for Quadruplex Formation: Computational, Synthetic and Analytical Studies

Abstract

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