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  • D. Posthuma
2011

Cijfes, Letters en Genen

Posthuma, D., 2011, geen: geen.

Research output: Book / ReportInaugural speechProfessional

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

Speliotes, E. K., Yerges-Armstrong, L. M., Wu, J., Hernaez, R., Kim, L. J., Palmer, C. D., Gudnason, V., Eiriksdottir, G., Garcia, M. E., Launer, L. J., Nalls, M. A., Clark, J. M., Mitchell, B. D., Shuldiner, A. R., Butler, J. L., Tomas, M., Hoffmann, U., Hwang, S. J., Massaro, J. M., O'Donnell, C. J. & 19 others, Sahani, D. V., Salomaa, V., Schadt, E. E., Schwartz, S. M., Siscovick, D. S., Posthuma, D., Voight, B. F., Carr, J. J., Feitosa, M. F., Harris, T. B., Fox, C. S., Smith, A. V., Kao, W. H. L., Hottenga, J. J., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Hirschhorn, J. N. & Borecki, I. B., 2011, In : PLoS Genetics. 7, 3, e1001324.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Genome-wide association study identifies five new schizophrenia loci

Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D. Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., St Clair, D., Corvin, A., Gurling, H., Werge, T., Rujescu, D., Blackwood, D. H., Pato, C. N., Malhotra, A. K. & 175 others, Purcell, S., Dudbridge, F., Neale, B. M., Rossin, L., Visscher, P. M., Posthuma, D., Ruderfer, D. M., Fanous, A., Stefansson, H., Steinberg, S., Mowry, B. J., Golimbet, V., de Hert, M., Jonsson, E. G., Bitter, I., Pietilainen, O. P., Collier, D. A., Tosato, S., Agartz, I., Albus, M., Alexander, M., Amdur, R. L., Amin, F., Bass, N., Bergen, S. E., Black, D. W., Borglum, A. D., Brown, M. A., Bruggeman, R., Buccola, N. G., Byerley, W. F., Cahn, W., Cantor, R. M., Carr, V. J., Catts, S. V., Choudhury, K., Cloninger, C. R., Cormican, P., Craddock, N., Danoy, P. A., Datta, S., de Haan, L., Demontis, D., Dikeos, D., Djurovic, S., Donnely, P., Donohoe, G., Duong, L., Dwyer, S., Fink-Jensen, A., Freedman, R., Freimer, N. B., Friedl, M., Georgieva, L., Giegling, I., Gill, M., Glenthoj, B., Godard, S., Hamshere, M., Hansen, M., Hartmann, A. M., Henskens, F. A., Hougaard, D. M., Hultman, C. M., Ingason, A., Jablensky, A. V., Jakobsen, K. D., Jay, M., Jurgens, G., Kahn, R. S., Keller, M. C., Kenis, G., Kenny, E., Kim, Y., Kirov, G. K., Konnerth, H., Konte, B., Krabbendam, L., Krasucki, R., Lasseter, V. K., Laurent, C., Lawrence, J., Lencz, T., Lerer, F. B., Liang, K. Y., Lichtenstein, P., Lieberman, J. A., Linszen, D. H., Lonnqvist, J., Loughland, C. M., Maclean, A. W., Maher, B. S., Maier, W., Mallet, J., Malloy, P., Mattheisen, M., Mattingsdal, M., McGhee, K. A., McGrath, J. J., McIntosh, A., McLean, D. E., McQuillin, A., Melle, I., Michie, P. T., Milanova, V., Morris, D. W., Mors, O., Mortensen, P. B., Moskvina, V., Muglia, P., Myin-Germeys, I., Nertney, D. A., Nestadt, G., Nielsen, J., Nikolov, I., Nordentoft, M., Norton, N., Nothen, M. M., O'Dushlaine, C. T., Olincy, A., Olsen, L., O'Neill, F. A., Orntoft, T. F., Owen, M. J., Pantelis, C., Papadimitriou, G., Pato, M. T., Peltonen, L., Petursson, H., Pickard, B., Pimm, J., Pulver, A. E., Puri, V., Quested, D., Quinn, E. M., Rasmussen, H. B., Rethelyi, J. M., Ribble, R., Rietschel, M., Riley, B. P., Ruggeri, M., Schall, U., Schulze, T. G., Schwab, S. G., Scott, R. J., Shi, J., Sigurdsson, E., Silvermann, J. M., Spencer, C. C., Stefansson, K., Strange, A., Strengman, E., Stroup, T. S., Suvisaari, J., Terenius, L., Thirumalai, S., Thygesen, J. H., Timm, S., Toncheva, D., van den Oord, E., van Os, J., van Winkel, R., Veldink, J., Walsh, D., Wang, A. G., Wiersma, D., Wildenauer, D. B., Williams, H. J., Williams, N. M., Wormley, B., Zammit, S., Sullivan, P. F., O'Donovan, M. C., Daly, M. J. & Gejman, P. V., 2011, In : Nature Genetics. 43, 10, p. 969-976

Research output: Contribution to JournalArticleAcademicpeer-review

Life events moderate variation in cognitive ability (g) in adults

Vinkhuyzen, A. A. E., van der Sluis, S. & Posthuma, D., 2011, In : Molecular Psychiatry. 16, 1, p. 4-6

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder

Liu, Y., Blackwood, D. H., Caesar, S., de Geus, E. J. C., Farmer, A., Ferreira, M. A. R., Ferrier, I. N., Fraser, C., Gordon-Smith, K., Green, E. K., Grozeva, D., Gurling, H. M., Hamshere, M. L., Heutink, P., Holmans, P. A., Hoogendijk, W. J. G., Hottenga, J. J., Jones, L., Jones, I. R., Kirov, G. & 24 others, Lin, D., McGuffin, P., Moskvina, V., Nolen, W. A., Perlis, R. H., Posthuma, D., Scolnick, E. M., Smit, A. B., Smit, J. H., Smoller, J. W., St Clair, D., van Dyck, R., Verhage, M., Willemsen, G., Young, A. H., Zandbelt, T., Boomsma, D. I., Craddock, N., O’Donovan, M. C., Owen, M. J., Penninx, B. W. J. H., Purcell, S., Sklar, P. & Sullivan, P. F., 2011, In : Molecular Psychiatry. 16, 1, p. 2-4

Research output: Contribution to JournalArticleAcademicpeer-review

Poor replication of candidate genes for major depressive disorder using genome-wide association data.

Bosker, F. J., Hartman, C. A., Nolte, I. M., Prins, B. P., Terpstra, P., Posthuma, D., van Veen, T., Willemsen, G., DeRijk, R. H., de Geus, E. J. C., Hoogendijk, W. J. G., Sullivan, P. F., Penninx, B. W. J. H., Boomsma, D. I., Snieder, H. & Nolen, W. A., 2011, In : Molecular Psychiatry. 16, 5, p. 516-532

Research output: Contribution to JournalArticleAcademicpeer-review

The ATXN1 and TRIM31 Genes Are Related to Intelligence in an ADHD Background: Evidence From a Large Collaborative Study Totaling 4,963 Subjects

Rizzi, T. S., Arias-Vasquez, A., Rommelse, N., Kuntsi, J., Anney, R., Asherson, P., Buitelaar, J., Banaschewski, T., Ebstein, R., Ruano, D., van der Sluis, S., Markunas, C. A., Garrett, M. E., Ashley-Koch, A. E., Kollins, S. H., Anastopoulos, A. D., Hnasell, N. K., Wright, M. J., Montgomery, G. W., Martin, N. G. & 23 others, Harris, S. E., Davies, G., Tenesa, A., Porteous, D. J., Starr, J. M., Deary, I. J., St Pourcain, B., Davey Smith, G., Timpson, N. J., Evans, D. M., Gill, M., Miranda, A., Mulas, F., Oades, R. D., Roeyers, H., Rothenberger, A., Sergeant, J. A., Sonuga-Barke, E., Steinhausen, H. C., Taylor, E., Faraone, S. V., Franke, B. & Posthuma, D., 2011, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156, 2, p. 145-157

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The Construction and Validation of an Abridged Version of the Autism-Spectrum Quotient (AQ-Short)

Hoekstra, R. A., Vinkhuyzen, A. A. E., Wheelwright, S., Bartels, M., Boomsma, D. I., Baron-Cohen, S., Posthuma, D. & van der Sluis, S., 2011, In : Journal of Autism and Developmental Disorders. 41, 5, p. 589-596

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

The Lin28/let-7 axis regulates glucose metabolism

Zhu, H., Shyh-Chang, N., Segre, A. V., Shinoda, G., Shah, S. P., Einhorn, W. S., Takeuchi, A., Engreitz, J. M., Hagan, J. P., Kharas, M. G., Urbach, A., Thornton, J. E., Triboulet, R., Gregory, R. I., Hottenga, J. J., de Geus, E. J. C., Posthuma, D., Willemsen, G., Boomsma, D. I., Altshuler, D. & 1 others, Daley, G. Q., 2011, In : Cell. 147, 1, p. 81-94

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2012

A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans

Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., Sandy An, S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M. & 11 others, Divers, J., Shriner, D., Adeyemo, A., Rotimi, C. N., Ng, M. C. Y., Langefeld, C. D., Freedman, B. I., Bowden, D. W., Posthuma, D., Penninx, B. W. J. H. & Sladek, R., 2012, In : PLoS ONE. 7, 1, p. e29202 e29202.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

A Note on False Positives and Power in G x E Modelling of Twin Data

van der Sluis, S., Posthuma, D. & Dolan, C. V., 2012, In : Behavior Genetics. 42, 1, p. 170-186

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Don't give up on GWAS

Sullivan, P. F., Penninx, B. W. J. H., Boomsma, D. I. & Posthuma, D., 2012, In : Molecular Psychiatry. 17, 1, p. 2-3

Research output: Contribution to JournalArticleAcademicpeer-review

Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes

de Jong, S., van Eijk, K., Zeegers, D. W., Strengman, E., Janson, E., Veldink, J. H., Van den Berg, L. H., Cahn, W., Kahn, R. S., Boks, M. P., Posthuma, D. & Ophoff, R. A., 2012, In : European Journal of Human Genetics. 20, 9, p. 1004-1008 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia

Lips, E. S., Cornelisse, L. N., Toonen, R. F. G., Min, J. L., Hultman, C., Holmans, P. A., O'Donovan, M. C., Purcell, S. M., Smit, A. B., Verhage, M., Sullivan, P. F., Visscher, P. M. & Posthuma, D., 2012, In : Molecular Psychiatry. 17, 10, p. 996-1006

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women

Fox, C. S., Liu, Y., White, C. C., Feitosa, M., Smith, A. V., Heard-Costa, N., Lohman, K., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Johnson, A. D., Foster, M. C., Greenawalt, D. M., Griffin, P., Ding, J., Newman, A. B., Tylavsky, F., Miljkovic, I., Kritchevsky, S. B. & 9 others, Launer, L., Garcia, M., Eiriksdottir, G., Posthuma, D., Carr, J. J., Gudnason, V., Harris, T. B., Cupples, L. A. & Borecki, I. B., 2012, In : PLoS Genetics. 8, 5, p. e1002695 e1002695.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Interaction Between Experience Seeking and Genetic and Environmental Influences on General Cognitive Ability

Vinkhuyzen, A. A. E., van der Sluis, S. & Posthuma, D., 2012, In : Twin Research and Human Genetics. 15, 1, p. 87-96

Research output: Contribution to JournalArticleAcademicpeer-review

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis

Derks, E. M., Vorstman, J. A. S., Ripke, S., Kahn, R. S., Posthuma, D. & Ophoff, R. A., 2012, In : PLoS ONE. 7, 6, p. e37852 e37852.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Dastani, Z., Hivert, M. F., Timpson, N. J., Perry, J. R., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L. P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S. & 101 others, Pankow, J. S., Uh, H. W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L. J., Greenwood, C. M., Ladouceur, M., Grimsby, J., Manning, A. K., Liu, C. T., Kooner, J., Mooser, V. E., Vollenweider, P., Kapur, K. A., Chambers, J., Wareham, N. J., Langenberg, C., Frants, R., Willems van Dijk, K., Oostra, B. A., Willems, S. M., Lamina, C., Winkler, T. W., Psaty, B. M., Tracy, R. P., Brody, J., Chen, I., Viikari, J., Kähönen, M., Pramstaller, P. P., Evans, D. M., St Pourcain, B., Sattar, N., Wood, A. R., Bandinelli, S., Carlson, O. D., Egan, J. M., Böhringer, S., van Heemst, D., Kedenko, L., Kristiansson, K., Nuotio, M. L., Loo, B. M., Harris, T., Garcia, M., Kanaya, A., Haun, M., Klopp, N., Wichmann, H. E., Deloukas, P., Katsareli, E., Couper, D. J., Duncan, B. B., Kloppenburg, M., Adair, L. S., Borja, J. B., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Wilson, J. G., Musani, G., Guo, X., Johnson, T., Semple, R., Teslovich, T. M., Allison, M. A., Redline, S., Buxbaum, S. G., Mohlke, K. L., Meulenbelt, I., Ballantyne, C. M., Dedoussis, G. V., Hu, F. B., Liu, Y., Paulweber, B., Spector, T. D., Slagboom, P. E., Ferrucci, L., Jula, A., Perola, M., Raitakari, O., Florez, J. C., Salomaa, V., Eriksson, J. G., Frayling, T. M., Hicks, A. A., Lehtimäki, T., Smith, G. D., Siscovick, D. S., Kronenberg, F., van Duijn, C. M., Loos, R. J., Waterworth, D., Meigs, J. B., Dupuis, J., Richards, J. B., Posthuma, D., Penninx, B. W. J. H., Vogelzangs, N. & Kathiresan, S., 2012, In : PLoS Genetics. 8, 3, p. e1002607 e1002607.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Reconsidering the Heritability of Intelligence in Adulthood: Taking Assortative Mating and Cultural Transmission into Account

Vinkhuyzen, A. A. E., van der Sluis, S., Maes, H. H. M. & Posthuma, D., 2012, In : Behavior Genetics. 42, 2, p. 187-198

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor

Keller, M. C., Simonson, M. A., Ripke, S., Neale, B. M., Gejman, P. V., Howrigan, D. P., Lee, S. H., Lencz, T., Levinson, D. F., Sullivan, P. F. & Posthuma, D., 2012, In : PLoS Genetics. 8, 4, p. e1002656 e1002656.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Supporting the generalist genes hypothesis for intellectual ability/disability: the case of SNAP25

Rizzi, T. S., Beunders, G., Rizzu, P., Sistermans, E. A., Twisk, J. W. R., van Mechelen, W., Deijen, J. B., Meijers-Heijboer, H., Verhage, M., Heutink, P. & Posthuma, D., 2012, In : Genes, Brain and Behavior. 11, 7, p. 767-771

Research output: Contribution to JournalArticleAcademicpeer-review

2013

A common biological basis of obesity and nicotine addiction

Thorgeirsson, T. E., Gudbjartsson, D. F., Sulem, P., Besenbacher, S., Styrkarsdottir, U., Thorleifsson, G., Walters, G. B., Furberg, H., Sullivan, P. F., Marchini, J., McCarthy, M. I., Steinthorsdottir, V., Thorsteinsdottir, U., Stefansson, K. & Posthuma, D., 2013, In : Translational Psychiatry. 3, p. e308 e308.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Additive genetic variation in schizophrenia risk is shared by populations of African and European descent

De Candia, T. R., Lee, S. H., Yang, J., Browning, B. L., Gejman, P. V., Levinson, D. F., Mowry, B. J., Hewitt, J. K., Goddard, M. E., O'Donovan, M. C., Purcell, S. M., Posthuma, D., Visscher, P. M., Wray, N. R. & Keller, M. C., 2013, In : American Journal of Human Genetics. 93, 3, p. 463-470

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

All SNPs are not created equal: Genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

Schork, A. J., Thompson, W. K., Pham, P., Torkamani, A., Roddey, J. C., Sullivan, P. F., Kelsoe, J., O'Donovan, M. C., Furberg, H., Absher, D., Agudo, A., Almgren, P., Ardissino, D., Assimes, T. L., Bandinelli, S., Barzan, L., Bencko, V., Benhamou, S., Benjamin, E. J., Bernardinelli, L. & 403 others, Bis, J., Boehnke, M., Boerwinkle, E., Boomsma, D. I., Brennan, P., Canova, C., Castellsagué, X., Chanock, S., Chasman, D. I., Conway, D. I., Dackor, J., de Geus, E. J. C., Duan, J., Elosua, R., Everett, B., Fabianova, E., Ferrucci, L., Foretova, L., Fortmann, S. P., Franceschini, N., Frayling, T. M., Furberg, C., Gejman, P. V., Groop, L., Gu, F., Guralnik, J., Hankinson, S. E., Haritunians, T., Healy, C., Hofman, A., Holcátová, I., Hunter, D. J., Hwang, S. J., Ioannidis, J. P. A., Iribarren, C., Jackson, A. U., Janout, V., Kaprio, J., Kim, Y., Kjaerheim, K., Knowles, J. W., Kraft, P., Ladenvall, C., Lagiou, P., Lanthrop, M., Lerman, C., Levinson, D. F., Levy, D., Li, M. D., Lin, D. Y., Lips, E. H., Lissowska, J., Lowry, R. B., Lucas, G., Macfarlane, T. V., Maes, H. H. M., Mannucci, P. M., Mates, D., Mauri, F., McGovern, J. A., McKay, J. D., McKnight, B., Melander, O., Merlini, P. A., Milaneschi, Y., Mohlke, K. L., O'Donnell, C. J., Pare, G., Penninx, B. W. J. H., Perry, J. R. B., Posthuma, D., Preis, S. R., Psaty, B., Quertermous, T., Ramachandran, V. S., Richiardi, L., Ridker, P. M., Rose, J., Rudnai, P., Salomaa, V., Sanders, A. R., Schwartz, S. M., Shi, J., Smit, J. H., Stringham, H. M., Szeszenia-Dabrowska, N., Tanaka, T., Taylor, K., Thacker, E. E., Thornton, L., Tiemeier, H., Tuomilehto, J., Uitterlinden, A. G., van Duijn, C. M., Vink, J. M., Vogelzangs, N., Voight, B. F., Walter, S., Willemsen, G., Zaridze, D., Znaor, A., Akil, H., Anjorin, A., Backlund, L., Badner, J. A., Barchas, J. D., Barrett, T., Bass, N., Bauer, M., Bellivier, F., Bergen, S. E., Berrettini, W., Blackwood, D., Bloss, C. S., Breen, G., Breuer, R., Bunner, W. E., Burmeister, M., Byerley, W. F., Caesar, S., Chambert, K., Cichon, S., St Clair, D., Collier, D. A., Corvin, A., Coryell, W. H., Craddock, N., Craig, D. W., Daly, M., Day, R., Degenhardt, F., Djurovic, S., Dudbridge, F., Edenberg, H. J., Elkin, A., Etain, B., Farmer, A. E., Ferreira, M. A., Ferrier, I., Flickinger, M., Foroud, T., Frank, J., Fraser, C., Frisén, L., Gershon, E. S., Gill, M., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grozeva, D., Guan, W., Gurling, H., Gustafsson, O., Hamshere, M. L., Hautzinger, M., Herms, S., Hipolito, M., Holmans, P. A., Hultman, C. M., Jamain, S., Jones, E. G., Jones, I., Jones, L., Kandaswamy, R., Kennedy, J. L., Kirov, G. K., Koller, D. L., Kwan, P., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Lee, P. H., Li, J., Lichtenstein, P., Lin, D., Liu, C., Lohoff, F. W., Lucae, S., Mahon, P. B., Maier, W., Martin, N. G., Mattheisen, M., Matthews, K., Mattingsdal, M., McGhee, K. A., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McLean, A. W., McMahon, F. J., McQuillin, A., Meier, S., Melle, I., Meng, F., Mitchell, P. B., Montgomery, G. W., Moran, J., Morken, G., Morris, D. W., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Myers, R. M., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V. L., Nöthen, M. M., Nurnberger, J. I., Nwulia, E. A., O'Dushlaine, C., Osby, U., Óskarsson, H., Owen, M. J., Petursson, H., Pickard, B. S., Porgeirsson, P., Potash, J. B., Propping, P., Purcell, S. M., Quinn, E., Raychaudhuri, S., Rice, J., Rietschel, M., Ruderfer, D., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schofield, P. R., Schulze, T. G., Schumacher, J., Schwarz, M. M., Scolnick, E., Scott, L. J., Shilling, P. D., Sigurdsson, E., Sklar, P., Smith, E. N., Stefansson, H., Stefansson, K., Steffens, M., Steinberg, S., Strauss, J., Strohmaier, J., Szelinger, S., Thompson, R. C., Tozzi, F., Treutlein, J., Vincent, J. B., Watson, S. J., Wienker, T. F., Williamson, R., Witt, S. H., Wright, A., Xu, W., Young, A. H., Zandi, P. P., Zhang, P., Zöllner, S., Agartz, I., Albus, M., Alexander, M., Amdur, R. L., Amin, F., Bitter, I., Black, D. W., Børglum, A. D., Brown, M. A., Bruggeman, R., Buccola, N. G., Cahn, W., Cantor, R. M., Carr, V. J., Catts, S. V., Choudhury, K., Cloninger, C. R., Cormican, P., Danoy, P. A., Datta, S., DeHert, M., Demontis, D., Dikeos, D., Donnelly, P., Donohoe, G., Duong, L., Dwyer, S., Fanous, A., Fink-Jensen, A., Freedman, R., Freimer, N. B., Friedl, M., Georgieva, L., Giegling, I., Glenthoj, B., Godard, S., Golimbet, V., de Haan, L., Hansen, M., Hansen, T., Hartmann, A. M., Henskens, F. A., Hougaard, D. M., Ingason, A., Jablensky, A. V., Jakobsen, K. D., Jay, M., Jönsson, E. G., Jürgens, G., Kahn, R. S., Keller, M. C., Kendler, K. S., Kenis, G., Kenny, E., Konnerth, H., Konte, B., Krabbendam, L., Krasucki, R., Lasseter, V. K., Laurent, C., Lencz, T., Lerer, F. B., Liang, K. Y., Lieberman, J. A., Linszen, D. H., Lönnqvist, J., Loughland, C. M., Maclean, A. W., Maher, B. S., Malhotra, A. K., Mallet, J., Malloy, P., McGrath, J. J., McLean, D. E., Michie, P. T., Milanova, V., Mors, O., Mortensen, P. B., Mowry, B. J., Myin-Germeys, I., Neale, B., Nertney, D. A., Nestadt, G., Nielsen, J., Nordentoft, M., Norton, N., O'Neill, F., Olincy, A., Olsen, L., Ophoff, R. A., Orntoft, T. F., van Os, J., Pantelis, C., Papadimitriou, G., Pato, C. N., Peltonen, L., Pickard, B., Pietilainen, O. P., Pimm, J., Pulver, A. E., Puri, V., Quested, D., Rasmussen, H. B., Rethelyi, J. M., Ribble, R., Riley, B. P., Rossin, L., Ruggeri, M., Rujescu, D., Schall, U., Schwab, S. G., Scott, R. J., Silverman, J. M., Spencer, C. C., Strange, A., Strengman, E., Stroup, T. S., Suvisaari, J., Terenius, L., Thirumalai, S., Timm, S., Toncheva, D., Tosato, S., van den Oord, E. J., Veldink, J., Visscher, P. M., Walsh, D., Wang, A. G., Werge, T., Wiersma, D., Wildenauer, D. B., Williams, H. J., Williams, N. M., van Winkel, R., Wormley, B., Zammit, S., Schork, N. J., Andreassen, O. A. & Dale, A. M., 2013, In : PLoS Genetics. 9, 4, p. e1003449 e1003449.

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Open Access

Attentional switching forms a genetic link between attention problems and autistic traits in adults

Polderman, T. J. C., Hoekstra, R. A., Vinkhuyzen, A. A. E., Sullivan, P. F., van der Sluis, S. & Posthuma, D., 2013, In : Psychological Medicine. 43, 9, p. 1985-1996

Research output: Contribution to JournalArticleAcademicpeer-review

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CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation

De Rubeis, S., Pasciuto, E., Li, K. W., Fernández, E., Di Marino, D., Buzzi, A., Ostroff, L. E., Klann, E., Zwartkruis, F. J., Komiyama, N. H., Grant, S. G., Poujol, C., Choquet, D., Achsel, T., Posthuma, D., Smit, A. B. & Bagni, C., 2013, In : Neuron. 79, 6, p. 1169-1182

Research output: Contribution to JournalArticleAcademicpeer-review

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Exonic Deletions in AUTS2 Cause a Syndromic Form of Intellectual Disability and Suggest a Critical Role for the C Terminus

Beunders, G., Voorhoeve, E., Golzio, C., Pardo, L. M., Rosenfeld, J. A., Talkowski, M. E., Simonic, I., Lionel, A. C., Vergult, S., Pyatt, R. E., van de Kamp, J. M., Nieuwint, A. W. M., Weiss, M. M., Rizzu, P., Verwer, L. E. N. I., van Spaendonk, R. M. L., Shen, Y. P., Wu, B. L., Yu, T. T., Yu, Y. G. & 43 others, Chiang, C., Gusella, J. F., Lindgren, A. M., Morton, C. C., van Binsbergen, E., Bulk, S., van Rossem, E., Vanakker, O., Armstrong, R., Park, S. M., Greenhalgh, L., Maye, U., Neill, N. J., Abbott, K. M., Sell, S., Ladda, R., Farber, D. M., Bader, P. I., Cushing, T., Drautz, J. M., Konczal, L., Nash, P., de Los Reyes, E., Carter, M. T., Hopkins, E., Marshall, C. R., Osborne, L. R., Gripp, K. W., Thrush, D. L., Hashimoto, S., Gastier-Foster, J. M., Astbury, C., Ylstra, B., Meijers-Heijboer, E. J., Posthuma, D., Menten, B., Mortier, G., Scherer, S. W., Eichler, E. E., Girirajan, S., Katsanis, N., Groffen, A. J. A. & Sistermans, E. A., 2013, In : American Journal of Human Genetics. 92, 2, p. 210-220

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

FADS2 Genetic Variance in Combination with Fatty Acid Intake Might Alter Composition of the Fatty Acids in Brain

Rizzi, T. S., van der Sluis, S., Derom, C., Thiery, E., van Kesteren, R. E., Jacobs, N., van Gestel, S., Vlietinck, R., Verhage, M., Heutink, P. & Posthuma, D., 2013, In : PLoS ONE. 8, 6, p. e68000 e68000.

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Genes encoding heterotrimeric G-proteins are associated with gray matter volume variations in the medial frontal cortex

Chavarría-Siles, I. M., Rijpkema, M., Arias-Vasquez, A., Verhage, M., Franke, B., Fernández, G. & Posthuma, D., 2013, In : Cerebral Cortex. 23, 5, p. 1025-1030

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 350 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Buccola, N. G., Buitelaar, J. K., Bunney, W. E., Buxbaum, J. D., Byerley, W. F., Byrne, E. M., Caesar, S., Cahn, W., Cantor, R. M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Cloninger, C. R., Collier, D. A., Cook, E. H., Coon, H., Corman, B., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Crosbie, J., Cuccaro, M. L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., de Geus, E. J. C., Degenhardt, F., Djurovic, S., Donohoe, G., Doyle, A. E., Duan, J., Dudbridge, F., Duketis, E., Ebstein, R. P., Edenberg, H. J., Elia, J., Ennis, S., Etain, B., Fanous, A., Farmer, A. E., Ferrier, I. N., Flickinger, M., Fombonne, E., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Freitag, C., Friedl, M., Frisén, L., Gallagher, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Geschwind, D. H., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grice, D. E., Gross, M., Grozeva, D., Guan, W., Gurling, H., de Haan, L., Haines, J. L., Hakonarson, H., Hallmayer, J., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hoogendijk, W. J. G., Hottenga, J. J., Hultman, C. M., Hus, V., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, I., Jones, L., Tzeng, J. Y., Kähler, A. K., Kahn, R. S., Kandaswamy, R., Keller, M. C., Kennedy, J. L., Kenny, E., Kent, L., Kim, Y., Kirov, G. K., Klauck, S. M., Klei, L., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krabbendam, L., Krasucki, R., Kuntsi, J., Kwan, P., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Ledbetter, D. H., Lee, P. H., Lencz, T., Lesch, K. P., Levinson, D. F., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Liu, C., Lohoff, F. W., Loo, S. K., Lord, C., Lowe, J. K., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Maestrini, E., Magnusson, P. K. E., Mahon, P. B., Maier, W., Malhotra, A. K., Mane, S. M., Martin, C. L., Martin, N. G., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S. A., McGhee, K. A., McGough, J. J., McGrath, P. J., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McLean, A. W., McMahon, F. J., McMahon, W. M., McQuillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Meyer, J., Middeldorp, C. M., Middleton, L., Milanova, V., Miranda, A., Monaco, A. P., Montgomery, G. W., Moran, J. L., Moreno-De Luca, D., Morken, G., Morris, D. W., Morrow, E. M., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Murtha, M., Myers, R. M., Myin-Germeys, I., Neale, M. C., Nelson, S. F., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V. L., Nolen, W. A., Nöthen, M. M., Nurnberger, J. I., Nwulia, E. A., Nyholt, DR., O'Dushlaine, C., Oades, R. D., Olincy, A., Oliveira, G., Olsen, L., Ophoff, R. A., Osby, U., Owen, M. J., Palotie, A., Parr, J. R., Paterson, A. D., Pato, C. N., Pato, M. T., Penninx, B. W. J. H., Pergadia, M. L., Pericak-Vance, M. A., Pickard, B. S., Pimm, J., Piven, J., Posthuma, D., Potash, J. B., Poustka, F., Propping, P., Puri, V., Quested, D., Quinn, E. M., Ramos-Quiroga, J. A., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Ribasés, M., Rice, J. P., Rietschel, M., Roeder, K., Roeyers, H., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Sanders, S. J., Santangelo, S., Sergeant, J. A., Schachar, R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Scherer, S. W., Schork, N. J., Schulze, T. G., Schumacher, J., Schwarz, M., Scolnick, E., Scott, L. J., Shi, J., Shilling, P. D., Shyn, S. I., Silverman, J. M., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E. J., St Clair, D., State, M., Steffens, M., Steinhausen, H. C., Strauss, J., Strohmaier, J., Stroup, T. S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Todorov, A. A., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J. C. G., Grootheest, G., van Os, J., Vicente, A., Vieland, V., Vincent, J. B., Visscher, P. M., Walsh, C. A., Wassink, T. H., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Wijsman, E. M., Willemsen, G., Williams, N., Willsey, A. J., Witt, S. H., Xu, W., Young, A. H., Yu, T. W., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S., Devlin, B., Kelsoe, J., Sklar, P., Daly, M. J., O'Donovan, M. C., Craddock, N., Sullivan, P. F., Smoller, J. W., Kendler, K. S. & Wray, N. R., 2013, In : Nature Genetics. 45, 9, p. 984-994

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Open Access

Genetic schizophrenia risk variants jointly modulate total brain and white matter volume

Terwisscha van Scheltinga, A. F., Bakker, S. C., Haren, N. E., Derks, E. M., Buizer-Voskamp, J. E., Boos, H. B., Cahn, W., Hulshoff Pol, H. E., Ripke, S., Ophoff, R. A., Posthuma, D. & Kahn, R. S., 2013, In : Biological Psychiatry. 73, 6, p. 525-531

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Ripke, S., O'Dushlaine, C., Chambert, K., Moran, J. L., Kähler, A. K., Akterin, S., Bergen, S. E., Collins, A. L., Crowley, J. J., Fromer, M., Kim, Y., Lee, S. H., Magnusson, P. K., Sanchez, N., Stahl, E. A., Williams, S., Wray, N. R., Xia, K., Bettella, F., Borglum, A. D. & 148 others, Bulik-Sullivan, B. K., Cormican, P., Craddock, N., de Leeuw, C. A., Durmishi, N., Gill, M., Golimbet, V., Hamshere, M. L., Holmans, P., Hougaard, D. M., Kendler, K. S., Lin, K., Morris, D. W., Mors, O., Mortensen, P. B., Neale, B. M., O'Neill, F. A., Owen, M. J., Milovancevic, M. P., Posthuma, D., Powell, J., Richards, A. L., Riley, B. P., Ruderfer, D., Rujescu, D., Sigurdsson, E., Silagadze, T., Smit, A. B., Stefansson, H., Steinberg, S., Suvisaari, J., Tosato, S., Verhage, M., Walters, T. J., Levinson, D. F., Gejman, P. V., Laurent, C., Mowry, B. J., O'Donovan, M. C., Pulver, A. E., Schwab, S. G., Wildenauer, D. B., Dudbridge, F., Shi, J., Albus, M., Alexander, M., Campion, D., Cohen, D., Dikeos, D., Duan, J., Eichhammer, P., Godard, S., Hansen, M., Lerer, F. B., Liang, K. Y., Maier, W., Mallet, J., Nertney, D. A., Nestadt, G., Norton, N., O'Neill, F. A., Papadimitriou, G. N., Ribble, R., Sanders, A. R., Silverman, J. M., Wormley, B., Arranz, M. J., Bakker, S., Bender, S., Bramon, E., Collier, D., Crespo-Facorro, B., Hall, J., Iyegbe, C., Jablensky, A., Kahn, R. S., Kalaydjieva, L., Lawrie, S. M., Lewis, C. M., Linszen, D. H., Mata, I., McIntosh, A., Murray, R. M., Ophoff, R. A., van Os, J., Walshe, M., Weisbrod, M., Wiersma, D., Donnely, P., Barasso, I., Blackwell, J. M., Brown, M. A., Casas, J. P., Corvin, A. P., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. C., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R. D., Strange, A., Su, Z., Vukcevic, D., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Tashakkori-Ghanbaria, A., Waller, M. J., Weston, P., Widaa, S., Whittaker, P., Barrroso, I., McCarthy, M. I., Spencer, C. C., Stefansson, K., Scolnick, E., Purcell, S., McCarroll, S. A., Sklar, P., Hultman, C. M. & Sullivan, P. F., 2013, In : Nature Genetics. 45, 10, p. 1150-1159

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association study of obsessive-compulsive disorder

Stewart, S. E., Yu, D., Scharf, J. M., Neale, B. M., Fagerness, J. A., Mathews, C. A., Arnold, P. D., Evans, P. D., Gamazon, E. R., Davis, L. K., Osiecki, L., McGrath, L., Haddad, S., Crane, J., Hezel, D., Illmann, C., Mayerfeld, C., Konkashbaev, A. I., Liu, C., Pluzhnikov, A. & 90 others, Tikhomirov, A., Edlund, C. K., Rauch, S. L., Moessner, R., Falkai, P., Maier, W., Ruhrmann, S., Grabe, H. J., Lennertz, L., Wagner, M., Bellodi, L., Cavallini, M. C., Richter, M. A., Cook, E. H., Kennedy, J. L., Rosenberg, D., Stein, D. J., Hemmings, S. M., Lochner, C., Azzam, A., Chavira, D. A., Fournier, E., Garrido, H., Sheppard, B., Umaña, P., Murphy, D. L., Wendland, J. R., Veenstra-Vanderweele, J., Denys, D., Blom, R., Deforce, D., van Nieuwerburgh, F., Westenberg, H. G., Walitza, S., Egberts, K., Renner, T., Miguel, E. C., Cappi, C., Hounie, A. G., Conceição do Rosário, M., Sampaio, A. S., Vallada, H., Nicolini, H., Lanzagorta, N., Camarena, B., Delorme, R., Leboyer, M., Pato, C. N., Pato, M. T., Voyiaziakis, E., Heutink, P., Cath, D. C., Posthuma, D., Smit, J. H., Samuels, J., Bienvenu, O. J., Cullen, B., Fyer, A. J., Grados, M. A., Greenberg, B. D., McCracken, J. T., Riddle, M. A., Wang, Y., Coric, V., Leckman, J. F., Bloch, M., Pittenger, C., Eapen, V., Black, D. W., Ophoff, R. A., Strengman, E., Cusi, D., Turiel, M., Frau, F., Macciardi, F., Gibbs, J. R., Cookson, M. R., Singleton, A., Hardy, J., Crenshaw, A. T., Parkin, M. A., Mirel, D. B., Conti, D. V., Purcell, S., Nestadt, G., Hanna, G. L., Jenike, M. A., Knowles, J. A., Cox, N. & Pauls, D. L., 2013, In : Molecular Psychiatry. 18, 7, p. 788-798

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association study of Tourette's syndrome

Scharf, J. M., Yu, D., Mathews, C. A., Neale, B. M., Stewart, S. E., Fagerness, J. A., Evans, P., Gamazon, E. R., Edlund, C. K., Service, S. K., Tikhomirov, A., Osiecki, L., Illmann, C., Pluzhnikov, A., Konkashbaev, A. I., Davis, L. K., Han, B., Crane, J., Moorjani, P., Crenshaw, A. T. & 78 others, Parkin, M. A., Reus, V. I., Lowe, T. L., Rangel-Lugo, M., Chouinard, S., Dion, Y., Girard, S., Cath, D. C., Smit, J. H., King, R. A., Fernandez, T. V., Leckman, J. F., Kidd, K. K., Kidd, J. R., Pakstis, A. J., State, M. W., Herrera, L. D., Romero, R., Fournier, E., Sandor, P., Barr, C. L., Phan, N., Gross-Tsur, V., Benarroch, F., Pollak, Y., Budman, C. L., Bruun, R. D., Erenberg, G., Naarden, A. L., Lee, P. C., Weiss, N., Kremeyer, B., Berrio, G. B., Campbell, D. D., Cardona Silgado, J. C., Ochoa, W. C., Mesa Restrepo, S. C., Muller, H., Valencia Duarte, A. V., Lyon, G. J., Leppert, M., Morgan, J., Weiss, R., Grados, M. A., Anderson, K., Davarya, S., Singer, H., Walkup, J., Jankovic, J., Tischfield, J. A., Heiman, G. A., Gilbert, D. L., Hoekstra, P. J., Robertson, M. M., Kurlan, R., Liu, C., Gibbs, J. R., Singleton, A., Hardy, J., Strengman, E., Ophoff, R. A., Wagner, M., Moessner, R., Mirel, D. B., Posthuma, D., Sabatti, C., Eskin, E., Conti, D. V., Knowles, J. A., Ruiz-Linares, A., Rouleau, G. A., Purcell, S., Heutink, P., Oostra, B. A., McMahon, W. M., Freimer, N. B., Cox, N. J. & Pauls, D. L., 2013, In : Molecular Psychiatry. 18, 6, p. 721-728

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC

Hamshere, M. L., Walters, J. T., Smith, R., Richards, A. L., Green, E., Grozeva, D., Jones, I., Forty, L., Jones, L., Gordon-Smith, K., O'Neill, T., Kendler, K. S., Sklar, P., Purcell, S., Kranz, J., Posthuma, D., Morris, D., Gill, M., Holmans, P., Craddock, N. & 3 others, Corvin, A., Owen, M. J. & O'Donovan, M. C., 2013, In : Molecular Psychiatry. 18, 6, p. 708-712

Research output: Contribution to JournalArticleAcademicpeer-review

GWAS of 126559 Individuals Identifies Genetic Variants Associated with Educational Attainment

Rietveld, C. A., Medland, S. E., Derringer, J., Yang, J., Esko, T., Martin, N. W., Westra, H. J., Shakhbazov, K., Abdellaoui, A., Agrawal, A., Albrecht, E., Alizadeh, BZ., Amin, N., Barnard, J., Baumeister, S. E., Benke, K. S., Bielak, L. F., Boatman, J. A., Boyle, P. A., Davies, G. & 182 others, de Leeuw, C. A., Eklund, N., Evans, D. S., Fehrmann, R. S., Fischer, K., Gieger, C., Gjessing, H. K., Hägg, S., Harris, J. R., Hayward, C., Holzapfel, C., Ibrahim-Verbaas, C. A., Ingelsson, E., Jacobsson, B., Joshi, P. K., Jugessur, A., Kaakinen, M., Kanoni, S., Karjalainen, J., Kolcic, I., Kristiansson, K., Kutalik, Z., Lahti, J., Lee, S. H., Lin, P., Lind, P. A., Liu, Y., Lohman, K., Loitfelder, M., McMahon, G., Vidal, P. M., Meirelles, O., Milani, L., Myhre, R., Nuotio, M. L., Oldmeadow, C. J., Petrovic, K. E., Peyrot, W. J., Polasek, O., Quaye, L., Reinmaa, E., Rice, J. P., Rizzi, T. S., Schmidt, H., Schmidt, R., Smith, A. V., Smith, J. A., Tanaka, T., Terracciano, A., van der Loos, M. J., Vitart, V., Völzke, H., Wellmann, J., Yu, L., Zhao, W., Allik, J., Attia, J. R., Bandinelli, S., Bastardot, F., Beauchamp, J., Bennett, D. A., Berger, K., Bierut, L. J., Boomsma, D. I., Bültmann, U., Campbell, H., Chabris, C. F., Cherkas, L., Chung, M. K., Cucca, F., de Andrade, M., Jager, P. L., de Neve, J. E., Deary, I. J., Dedoussis, G. V., Deloukas, P., Dimitriou, M., Eiriksdottir, G., Elderson, M. F., Eriksson, J. G., Evans, D. M., Faul, J. D., Ferrucci, L., Garcia, M. E., Grönberg, H., Gudnason, V., Hall, P., Harris, J. M., Harris, T. B., Hastie, N. D., Heath, A. C., Hernandez, D. G., Hoffmann, W., Hofman, A., Holle, R., Holliday, E. G., Hottenga, J. J., Iacono, W. G., Illig, T., Järvelin, M. R., Kähönen, M., Kaprio, J., Kirkpatrick, R. M., Kowgier, M., Latvala, A., Launer, L. J., Lawlor, D. A., Lehtimäki, T., Li, J., Lichtenstein, P., Lichtner, P., Liewald, D. C., Madden, P. A. F., Magnusson, P. K. E., Mäkinen, T. E., Masala, M., McGue, M., Metspalu, A., Mielck, A., Miller, M. B., Montgomery, G. W., Mukherjee, S., Nyholt, DR., Oostra, B. A., Palmer, L. J., Palotie, A., Penninx, B. W. J. H., Perola, M., Peyser, P. A., Preisig, M., Räikkönen, K., Raitakari, O. T., Realo, A., Ring, S. M., Ripatti, S., Rivadeneira, F., Rudan, I., Rustichini, A., Salomaa, V., Sarin, A. P., Schlessinger, D., Scott, R. J., Snieder, H., St Pourcain, B., Starr, J. M., Sul, J. H., Surakka, I., Svento, R., Teumer, A., Tiemeier, H., van Rooij, F. J., Wagoner, D. R., Vartiainen, E., Viikari, J., Vollenweider, P., Vonk, J. M., Waeber, G., Weir, D. R., Wichmann, H. E., Widen, E., Willemsen, G., Wilson, J. F., Wright, A. F., Conley, D., Davey Smith, G., Franke, L., Groenen, P. J. F., Johannesson, M., Kardia, S., Krueger, R. F., Laibson, D., Martin, N. G., Meyer, M. N., Posthuma, D., Thurik, A. R., Timpson, N. J., Uitterlinden, A. G., van Duijn, C. M., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 2013, In : Science. 340, 6139, p. 1467-1471

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Smoller, J. W., Ripke, S., Lee, P. H., Neale, B., Nurnberger, J. I., Santangelo, S., Sullivan, P. F., Perlis, R. H., Purcell, S. M., Fanous, A., Neale, M. C., Rietschel, M., Schulze, T. G., Thapar, A., Anney, R., Buitelaar, J. K., Farone, S. V., Hoogendijk, W. J. G., Levinson, D. F., Lesch, K. P. & 291 others, Riley, B., Schachar, R., Sonuga-Barke, E. J., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Arking, D., Asherson, P., Azevedo, M. H., Backlund, L., Badner, J. A., Banaschewski, T., Barchas, J. D., Barnes, M. R., Bass, N., Bauer, M. C. R., Bellivier, F., Bergen, S. E., Berrettini, W., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Buccola, N. G., Bunner, W. E., Burmeister, M., Buxbaum, J. D., Byerley, W. F., Sian, C., Cantor, R. M., Chakravarti, A., Chambert, K., Chicon, S., Cloniger, C. R., Collier, D. A., Cook, E., Coon, H., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Curtis, D., Czamara, D., Daly, M., Datta, S., Day, R., de Geus, E. J. C., Degenhardt, F., Devlin, B., Srdjan, D., Doyle, A. E., Duan, J., Dudbridge, F., Edenberg, H. J., Elkin, A., Etain, B., Farmer, A. E., Ferreira, M. A. R., Ferrier, I. N., Flickinger, M., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Friedl, M., Frisén, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Gross, M., Grozeva, D., Guan, W., Gurling, H., Gustafsson, O., Hakonarson, H., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hottenga, J. J., Hultman, C. M., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, L., Jones, I., Jung-Ying, T., Kahler, A., Kandaswamy, R., Keller, M. C., Kelsoe, J., Kennedy, J. L., Kenny, E., Kim, Y., Kirov, G. K., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krasucki, R., Kuntsi, J., Phoenix, K., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Lencz, T., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D., Liu, C., Lohoff, F. W., Loo, S. K., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Magnusson, P., Mahon, P. B., Maier, W., Malhotra, A. K., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S., McGhee, K. A., McGough, J. J., McGrath, P. J., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McClean, A. W., McMahon, F. J., McQuillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Middeldorp, C. M., Middleton, L., Vihra, M., Mitchell, P. B., Montgomery, G. W., Moran, J., Morken, G., Morris, D. W., Moskvina, V., Mowry, B. J., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Myers, R. M., Nelson, S. F., Nievergelt, C. M., Nikolovq, I., Nimgaonkar, V. L., Nolen, W. A., Nöthen, M. M., Nwulia, E. A., Nyholt, DR., O'Donovan, M. C., O'Dushlaine, C., Oades, R. D., Olincy, A., Olsen, L., Ophoff, R. A., Osby, U., Óskarsson, H., Owen, M. J., Palotie, A., Pato, M. T., Pato, C. N., Penninx, B. W. J. H., Pergadia, M. L., Petursson, H., Pickard, B. S., Pimm, J., Piven, J., Porgeirsson, P., Posthuma, D., Potash, J. B., Propping, J., Puri, V., Quested, D., Quinn, E. M., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Rice, J., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Schofield, P. R., Schork, N. J., Schumacher, J., Schwarz, M. M., Scolnick, E., Scott, L. J., Shi, J., Shillling, P. D., Shyn, S. I., Sigurdsson, E., Silverman, J. M., Sklar, P., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E., St Clair, D., State, M., Stefansson, K., Stefansson, H., Steffans, M., Steinberg, S., Steinhausen, H. C., Strauss, J., Strohmaier, J., Stroup, T. S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J., Grootheest, G., Vieland, V., Vincent, J. B., Visscher, P. M., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Willemsen, G., Williamson, R., Witt, S. H., Wray, N. R., Wright, A., Xu, W., Young, A. H., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S. & Kendler, K. S., 2013, In : Lancet. 381, 9875, p. 1371-1379

Research output: Contribution to JournalArticleAcademicpeer-review

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

Andreassen, O. A., Djurovic, S., Thompson, W. K., Schork, A. J., Kendler, K. S., O'Donavan, M. C., Rujescu, D., Werge, T., van de Bunt, M., Morris, A. P., McCarthy, M. I., Roddey, J. C., McEvoy, L. K., Desikan, R. S., Dale, A. M. & Posthuma, D., 2013, In : American Journal of Human Genetics. 92, 2, p. 197-209

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Mining the human phenome using allelic scores that index biological intermediates

Evans, D. M., Brion, M. J., Paternoster, L., Kemp, J. P., McMahon, G., Munafò, M., Whitfield, J. B., Medland, S. E., Montgomery, G. W., Timpson, N. J., St. Pourcain, B., Lawlor, D. A., Martin, N. G., Dehghan, A., Hirschhorn, J., Davey Smith, G. & Posthuma, D., 2013, In : PLoS Genetics. 9, 10, p. e1003913 e1003913.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

Davis, L. K., Yu, D., Keenan, C. L., Gamazon, E. R., Konkashbaev, A. I., Derks, E. M., Neale, B. M., Yang, J., Lee, S. H., Evans, P., Barr, C. L., Bellodi, L., Benarroch, F., Berrio, G. B., Bienvenu, O. J., Bloch, M. H., Blom, R. M., Bruun, R. D., Budman, C. L., Camarena, B. & 110 others, Campbell, D., Cappi, C., Cardona Silgado, J. C., Cath, D. C., Cavallini, M. C., Chavira, D. A., Chouinard, S., Conti, D. V., Cook, E. H., Coric, V., Cullen, B. A., Deforce, D., Delorme, R., Dion, Y., Edlund, C. K., Egberts, K., Falkai, P., Fernandez, T. V., Gallagher, P. J., Garrido, H., Geller, D., Girard, S. L., Grabe, H. J., Grados, M. A., Greenberg, B. D., Gross-Tsur, V., Haddad, S., Heiman, G. A., Hemmings, S. M., Hounie, A. G., Illmann, C., Jankovic, J., Jenike, M. A., Kennedy, J. L., King, R. A., Kremeyer, B., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J. F., Lennertz, L., Liu, C., Lochner, C., Lowe, T. L., Macciardi, F., McCracken, J. T., McGrath, L. M., Mesa Restrepo, S. C., Moessner, R., Morgan, J., Muller, H., Murphy, D. L., Naarden, A. L., Ochoa, W. C., Ophoff, R. A., Osiecki, L., Pakstis, A. J., Pato, M. T., Piacentini, J., Pittenger, C., Pollak, Y., Rauch, S. L., Renner, T. J., Reus, V. I., Richter, M. A., Riddle, M. A., Robertson, M. M., Romero, R., Rosàrio, M. C., Rosenberg, D., Rouleau, G. A., Ruhrmann, S., Ruiz-Linares, A., Sampaio, A. S., Samuels, J., Sandor, P., Sheppard, B., Singer, H. S., Smit, J. H., Stein, D. J., Strengman, E., Tischfield, J. A., Valencia Duarte, A. V., Vallada, H., van Nieuwerburgh, F., Veenstra-Vanderweele, J., Walitza, S., Wang, Y., Wendland, J. R., Westenberg, H. G., Shugart, Y. Y., Miguel, E. C., McMahon, W., Wagner, M., Nicolini, H., Posthuma, D., Hanna, G. L., Heutink, P., Denys, D., Arnold, P. D., Oostra, B. A., Nestadt, G., Freimer, N. B., Pauls, D. L., Wray, N. R., Stewart, S. E., Mathews, C. A., Knowles, J. A., Cox, N. J. & Scharf, J. M., 2013, In : PLoS Genetics. 9, 10, p. e1003864 e1003864.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Power in GWAS: lifting the curse of the clinical cut-off

van der Sluis, S., Posthuma, D., Nivard, M. G., Verhage, M. & Dolan, C. V., 2013, In : Molecular Psychiatry. 18, 1, p. 2-3

Research output: Contribution to JournalArticleAcademicpeer-review

Schizophrenia genetic variants are not associated with intelligence

Terwisscha van Scheltinga, A. F., Bakker, S. C., van Haren, N. E., Derks, E. M., Buizer-Voskamp, J. E., Cahn, W., Ripke, S., Ophoff, R. A., Posthuma, D. & Kahn, R. S., 2013, In : Psychological Medicine. 43, 12, p. 2563-2570

Research output: Contribution to JournalArticleAcademicpeer-review

TATES: efficient multivariate genotype-phenotype analysis for genome-wide association studies

van der Sluis, S., Posthuma, D. & Dolan, C. V., 2013, In : PLoS Genetics. 9, 1, p. e1003235 e1003235.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

What have we learned from recent twin studies about the etiology of neurodevelopmental disorders?

Posthuma, D. & Polderman, T. J. C., 2013, In : Current Opinion in Neurology. 26, 2, p. 111-121

Research output: Contribution to JournalArticleAcademicpeer-review

2014

Biological insights from 108 schizophrenia-associated genetic loci

Ripke, S., Neale, B. M., Posthuma, D., Sullivan, P. F. & O'Donovan, M. C., 2014, In : Nature. 511, 7510, p. 421-427

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Childhood intelligence is heritable, highly polygenic and associated with FNBP1L

Benyamin, B., Pourcain, B., Davis, O. S., Davies, G., Hansell, N. K., Brion, M. J., Kirkpatrick, R. M., Cents, R. A., Franić, S., Miller, M. B., Haworth, C. M., Meaburn, E., Price, T. S., Evans, D. M., Timpson, N., Kemp, J., Ring, S., McArdle, W., Medland, S. E., Yang, J. & 23 others, Harris, S. E., Liewald, D. C., Scheet, P., Xiao, X., Hudziak, J. J., de Geus, E. J. C., Jaddoe, V. W., Star, J. M., Verhulst, F. C., Pennell, C., Tiemeier, H., Iacono, W. G., Palmer, L. J., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Posthuma, D., McGue, M., Wright, M. J., Davey Smith, G., Deary, I. J., Plomin, R. & Visscher, P. M., 2014, In : Molecular Psychiatry. 19, 2, p. 253-258 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.

Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., de Leeuw, C. A., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A., Amin, N., Conley, D., Derringer, J. & 39 others, van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Lacono, W. G., Ibrahim-Verbaas, C. A., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Smith, B. H., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Davey Smith, G., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13790-13794

Research output: Contribution to JournalArticleAcademicpeer-review

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.

McGrath, L. M., Yu, D., Marshall, C., Davis, L. K., Thiruvahindrapuram, B., Li, B., Cappi, C., Gerber, G., Wolf, A., Schroeder, F. A., Osiecki, L., O'Dushlaine, C., Kirby, A., Illmann, C., Haddad, S., Gallagher, P., Fagerness, J. A., Barr, C. L., Bellodi, L., Benarroch, F. & 100 others, Bienvenu, O. J., Black, D. W., Bloch, M. H., Bruun, R. D., Budman, C. L., Camarena, B., Cath, D. C., Cavallini, M. C., Chouinard, S., Coric, V., Cullen, B., Delorme, R., Denys, D., Derks, E. M., Dion, Y., Rosário, M. C., Eapen, V., Evans, P., Falkai, P., Fernandez, T. V., Garrido, H., Geller, D., Grabe, H. J., Grados, M. A., Greenberg, B. D., Gross-Tsur, V., Grünblatt, E., Heiman, G. A., Hemmings, S. M., Herrera, L. D., Hounie, A. G., Jankovic, J., Kennedy, J. L., King, R. A., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J. F., Lennertz, L., Lochner, C., Lowe, T. L., Lyon, G. J., Macciardi, F., Maier, W., McCracken, J. T., McMahon, W., Murphy, D. L., Naarden, A. L., Neale, B. M., Nurmi, E., Pakstis, A. J., Pato, M. T., Piacentini, J., Pittenger, C., Pollak, Y., Reus, V. I., Richter, M. A., Riddle, M., Robertson, M. M., Rosenberg, D., Rouleau, G. A., Ruhrmann, S., Sampaio, A. S., Samuels, J., Sandor, P., Sheppard, B., Singer, H. S., Smit, J. H., Stein, D. J., Tischfield, J. A., Vallada, H., Veenstra-Vanderweele, J., Walitza, S., Wang, Y., Wendland, J. R., Shugart, Y. Y., Miguel, E. C., Nicolini, H., Oostra, B. A., Moessner, R., Wagner, M., Ruiz-Linares, A., Heutink, P., Nestadt, G., Freimer, N., Petryshen, T., Posthuma, D., Jenike, M. A., Cox, N. J., Hanna, G. L., Brentani, H., Scherer, S. W., Arnold, P. D., Stewart, S. E., Mathews, C. A., Knowles, J. A., Cook, E. H., Pauls, D. L., Wang, K. & Scharf, J. M., 2014, In : Journal of the American Academy of Child and Adolescent Psychiatry. 53, 8, p. 910-919

Research output: Contribution to JournalArticleAcademicpeer-review

Core Dimensions of Personality Broadly Account for the Link from Perceived Social Support to Symptoms of Depression and Anxiety

Lewis, G. J., Bates, T. C., Posthuma, D. & Polderman, T. J. C., 2014, In : Journal of Personality. 82, 4, p. 329-339

Research output: Contribution to JournalArticleAcademicpeer-review

Cortical thickness and inattention/hyperactivity symptoms in young children: a population-based study.

Mous, S. E., Muetzel, R. L., Marroun, H., Polderman, T. J. C., van der Lugt, A., Jaddoe, V. W., Hofman, A., Verhulst, F. C., Tiemeier, H., Posthuma, D. & White, T., 2014, In : Psychological Medicine. 44, 15, p. 3203-3213

Research output: Contribution to JournalArticleAcademicpeer-review