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  • A.H.M. Willemsen
2018

Are Migraine and Tension-Type Headache Genetically Related? An Investigation of Twin Family Data

Ligthart, L., Huijgen, A., Willemsen, G., De Geus, E. J. C. & Boomsma, D. I., Apr 2018, In : Twin Research and Human Genetics. 21, 2, p. 112-118 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project

Jelenkovic, A., Yokoyama, Y., Sund, R., Hur, Y. M., Harris, J. R., Brandt, I., Nilsen, T. S., Ooki, S., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Saudino, K. J., Stazi, M. A., Fagnani, C., Brescianini, S., Nelson, T. L., Whitfield, K. E., Knafo-Noam, A., Mankuta, D., Abramson, L. & 30 others, Cutler, T. L., Hopper, J. L., Llewellyn, C. H., Fisher, A., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Krueger, R. F., McGue, M., Pahlen, S., Alexandra Burt, S., Klump, K. L., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Willemsen, G., Bartels, M., van Beijsterveld, C. E. M., Craig, J. M., Saffery, R., Rasmussen, F., Tynelius, P., Heikkilä, K. & Boomsma, D. I., May 2018, In : Early Human Development. 120, p. 53-60 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Bidirectional prospective associations between cardiac autonomic activity and inflammatory markers

Hu, M. X., Lamers, F., Neijts, M., Willemsen, G., De Geus, E. J. C. & Penninx, B. W. J. H., 1 Jun 2018, In : Psychosomatic Medicine. 80, 5, p. 475-482 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts

Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y. M., Ullemar, V., Almqvist, C., Magnusson, P. K., Willemsen, G., Bartels, M., Beijsterveldt, C. E. V., Bogl, L. H., Pietiläinen, K. H., Vuoksimaa, E., Ji, F., Ning, F., Pang, Z., Nelson, T. L., Whitfield, K. E., Rebato, E., Llewellyn, C. H. & 30 others, Fisher, A., Bayasgalan, G., Narandalai, D., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Stazi, M. A., Fagnani, C., Brescianini, S., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Cutler, T. L., Hopper, J. L., Krueger, R. F., McGue, M., Pahlen, S., Craig, J. M., Saffery, R., Haworth, C. M., Plomin, R., Knafo-Noam, A., Mankuta, D., Abramson, L. & Boomsma, D. I., 19 Apr 2018, In : Scientific Reports. 8, 1, 6300.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Brain reward responses to food stimuli among female monozygotic twins discordant for BMI

Doornweerd, S., De Geus, E. J., Barkhof, F., van Bloemendaal, L., Boomsma, D. I., van Dongen, J., Drent, M. L., Willemsen, G., Veltman, D. J. & IJzerman, R. G., 8 Jun 2018, In : Brain Imaging and Behavior. 12, 3, p. 718-727 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

van der Lee, S. J., Teunissen, C. E., Pool, R., Shipley, M. J., Teumer, A., Chouraki, V., Melo van Lent, D., Tynkkynen, J., Fischer, K., Hernesniemi, J., Haller, T., Singh-Manoux, A., Verhoeven, A., Willemsen, G., de Leeuw, F. A., Wagner, H., van Dongen, J., Hertel, J., Budde, K., Willems van Dijk, K. & 28 others, Weinhold, L., Ikram, M. A., Pietzner, M., Perola, M., Wagner, M., Friedrich, N., Slagboom, P. E., Scheltens, P., Yang, Q., Gertzen, R. E., Egert, S., Li, S., Hankemeier, T., van Beijsterveldt, C. E. M., Vasan, R. S., Maier, W., Peeters, C. F. W., Jörgen Grabe, H., Ramirez, A., Seshadri, S., Metspalu, A., Kivimäki, M., Salomaa, V., Demirkan, A., Boomsma, D. I., van der Flier, W. M., Amin, N. & van Duijn, C. M., Jun 2018, In : Alzheimers & Dementia. 14, 6, p. 707-722 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Cohort profile: the Geoscience and Health Cohort Consortium (GECCO) in the Netherlands

Timmermans, E. J., Lakerveld, J., Beulens, J. W. J., Boomsma, D. I., Kramer, S. E., Oosterman, M., Willemsen, G., Stam, M., Nijpels, G., Schuengel, C., Smit, J. H., Brunekreef, B., Dekkers, J. E. C., Deeg, D. J. H., Penninx, B. W. J. H. & Huisman, M., 9 Jun 2018, In : BMJ Open. 8, 6, p. 1-14 14 p., e021597.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M. & 73 others, Araya, R., Bowes, L., Burns, M. R., Byrne, E. M., Coffey, J. C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J-J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., Meyer zu Schwabedissen, H., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van der Auwera, S., Wainwright, N. W., Wang, J-C., Willemsen, G., Anderson, I. M., Arolt, V., Åslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., de Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T. C., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, D. M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M. A., Nurnberger, J. I., Breslau, N. & Bierut, L. J., 2 Jan 2018, In : Molecular Psychiatry. 23, 1, p. 133-142 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis

Ward-Caviness, C. K., Huffman, J. E., Everett, K., Germain, M., Van Dongen, J., Hill, W. D., Jhun, M. A., Brody, J. A., Ghanbari, M., Du, L., Roetker, N. S., De Vries, P. S., Waldenberger, M., Gieger, C., Wolf, P., Prokisch, H., Koenig, W., O’Donnell, C. J., Levy, D., Liu, C. & 34 others, Truong, V., Wells, P. S., Trégouët, D. A., Tang, W., Morrison, A. C., Boerwinkle, E., Wiggins, K. L., McKnight, B., Guo, X., Psaty, B. M., Sotoodenia, N., Boomsma, D. I., Willemsen, G., Ligthart, L., Deary, I. J., Zhao, W., Ware, E. B., Kardia, S. L. R., Van Meurs, J. B. J., Uitterlinden, A. G., Franco, O. H., Eriksson, P., Franco-Cereceda, A., Pankow, J. S., Johnson, A. D., Gagnon, F., Morange, P. E., De Geus, E. J. C., Starr, J. M., Smith, J. A., Dehghan, A., Björck, H. M., Smith, N. L. & Peters, A., 25 Oct 2018, In : Blood. 132, 17, p. 1842-1850 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

DNA methylation signatures of educational attainment

Dongen, J. V., Bonder, M. J., Dekkers, K. F., Nivard, M. G., Iterson, M. V., Willemsen, G., Beekman, M., Spek, A. V. D., Meurs, J. B. J. V., Franke, L., Heijmans, B. T., Duijn, C. M. V., Slagboom, P. E. & Boomsma, D. I., 23 Mar 2018, In : npj Science of Learning 2018 3:1. 3, p. 1-14 14 p., 7.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Erratum to Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

The 23andMe Research Team & AAGC collaborators, 16 Aug 2018, In : Nature Genetics. 50, 9, 1 p.

Research output: Contribution to JournalComment / Letter to the editorAcademic

Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and 'Omics' Studies

Odintsova, V. V., Willemsen, G., Dolan, C. V., Hottenga, J. J., Martin, N. G., Slagboom, P. E., Ordoñana, J. R. & Boomsma, D. I., Jun 2018, In : Twin Research and Human Genetics. 21, 3, p. 239-252 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

23Andme Research Team, Abdellaoui, A., Peyrot, W. J., Hottenga, J. J., Vinkhuyzen, A. A. E., Willemsen, G., Boomsma, D. I., van Duijn, C. M., Penninx, B., Posthuma, D. & Uitterlinden, A. G., Aug 2018, In : Nature Genetics. 50, 8, p. 1112-1121 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Oct 2018, In : Nature Genetics. 50, 10, p. 1412-1431 20 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic and environmental factors affecting birth size variation: A pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts

Yokoyama, Y., Jelenkovic, A., Hur, Y. M., Sund, R., Fagnani, C., Stazi, M. A., Brescianini, S., Ji, F., Ning, F., Pang, Z., Knafo-Noam, A., Mankuta, D., Abramson, L., Rebato, E., Hopper, J. L., Cutler, T. L., Saudino, K. J., Nelson, T. L., Whitfield, K. E., Corley, R. P. & 40 others, Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Llewellyn, C. H., Fisher, A., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Krueger, R. F., McGue, M., Pahlen, S., Bartels, M., Van Beijsterveldt, C. E. M., Willemsen, G., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Rasmussen, F., Tynelius, P., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Rose, R. J., Pietiläinen, K. H., Sørensen, T. I. A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 1 Aug 2018, In : International Journal of Epidemiology. 47, 4, p. 1195-1206 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

LifeLines Cohort Study & CHARGE Inflammation Working Group, 1 Nov 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide analysis of DNA methylation in buccal cells: A study of monozygotic twins and mQTLs

Van Dongen, J., Ehli, E. A., Jansen, R., Van Beijsterveldt, C. E. M., Willemsen, G., Hottenga, J. J., Kallsen, N. A., Peyton, S. A., Breeze, C. E., Kluft, C., Heijmans, B. T., Bartels, M., Davies, G. E. & Boomsma, D. I., 25 Sep 2018, In : Epigenetics and Chromatin. 11, p. 1-14 14 p., 54.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 30 others, Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Posthuma, D., Smit, J. H., Willemsen, G., Boomsma, D. I. & Penninx, B. W. J. H., May 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

23Andme Research Team, 16 Jul 2018, In : Nature Genetics. 50, 8, p. 1072-1080 9 p.

Research output: Contribution to JournalLetterAcademicpeer-review

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

Hysi, P. G., Valdes, A. M., Liu, F., Furlotte, N. A., Evans, D. M., Bataille, V., Visconti, A., Hemani, G., McMahon, G., Ring, S. M., Smith, G. D., Duffy, D. L., Zhu, G., Gordon, S. D., Medland, S. E., Lin, B. D., Willemsen, G., Hottenga, J. J., Vuckovic, D., Girotto, G. & 24 others, Gandin, I., Sala, C., Concas, M. P., Brumat, M., Gasparini, P., Toniolo, D., Cocca, M., Robino, A., Yazar, S., Hewitt, A. W., Chen, Y., Zeng, C., Uitterlinden, A. G., Ikram, M. A., Hamer, M. A., Van Duijn, C. M., Nijsten, T., MacKey, D. A., Falchi, M., Boomsma, D. I., Martin, N. G., Hinds, D. A., Kayser, M. & Spector, T. D., May 2018, In : Nature Genetics. 50, 5, p. 652-656 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J-J., Allard, C., Barton, S. J., Espinosa, A. & 31 others, Marsh, J. A., Potter, C., Zhang, G., Ang, W., Berry, D. J., Bouchard, L., Das, S., Hakonarson, H., Heikkinen, J., Helgeland, Ø., Hocher, B., Hofman, A., Inskip, H. M., Jones, S. E., Kogevinas, M., Lind, P. A., Marullo, L., Medland, S. E., Murray, A., Murray, J. C., Njølstad, P. R., Nohr, E. A., Reichetzeder, C., Ring, S. M., Ruth, K. S., Santa-Marina, L., Scholtens, D. M., Willemsen, G., Bartels, M., Boomsma, D. I. & Early Growth Genetics (EGG) Consortium, 1 Feb 2018, In : Human Molecular Genetics. 27, 4, p. 742-756 15 p., ddx429.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 20 Dec 2018, In : PLoS ONE. 13, 12, p. 1-29 29 p., e0209160.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Gudmundsdottir, V., Pedersen, H. K., Allebrandt, K. V., Brorsson, C., van Leeuwen, N., Banasik, K., Mahajan, A., Groves, C. J., van de Bunt, M., Dawed, A. Y., Fritsche, A., Staiger, H., Simonis-Bik, A. M. C., Deelen, J., Kramer, M. H. H., Dietrich, A., Hübschle, T., Willemsen, G., Häring, H-U., de Geus, E. J. C. & 8 others, Boomsma, D. I., Eekhoff, E. M. W., Ferrer, J., McCarthy, M. I., Pearson, E. R., Gupta, R., Brunak, S. & 't Hart, L. M., 2 Jan 2018, In : PLoS ONE. 13, 1, p. e0189886 e0189886.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative

Boomsma, D. I., Davies, G. E., de Geus, E., Ehli, E. A., Finnicum, C. T. F., Mbarek, H., Willemsen, G. & MiBioGen Consortium Initiative, 8 Jun 2018, In : Microbiome. 6, 1, p. 101 101.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, Herder, C., Rathmann, W., Roden, M., Gieger, C., Kramer, M. H. H., van Heemst, D., Pedersen, H. K., Gudmundsdottir, V., Schulze, M. B., Pischon, T., de Geus, E. J. C., Boeing, H., Boomsma, D. I., Ziegler, A. G., Slagboom, P. E., Hummel, S., Beekman, M., Grallert, H., Brunak, S., McCarthy, M. I., Gupta, R., Pearson, E. R., Adamski, J. & 't Hart, L. M., 1 Jan 2018, In : Diabetologia. 61, 1, p. 117-129 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Metataxonomic Analysis of Individuals at BMI Extremes and Monozygotic Twins Discordant for BMI

Finnicum, C. T., Doornweerd, S., Dolan, C. V., Luningham, J. M., Beck, J. J., Willemsen, G., Ehli, E. A., Boomsma, D. I., Ijzerman, R. G., Davies, G. E. & De Geus, E. J. C., 1 Jun 2018, In : Twin Research and Human Genetics. 21, 3, p. 203-213 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E. & 31 others, Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Heckbert, S. R., Hottenga, J., Mbarek, H., Willemsen, G. & Australian Asthma Genetics Consortium (AAGC) collaborators, Jan 2018, In : Nature Genetics. 50, 1, p. 42-53 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Polygenic risk for alcohol consumption and its association with alcohol-related phenotypes: Do stress and life satisfaction moderate these relationships?

Mies, G. W., Verweij, K. J. H., Treur, J. L., Ligthart, L., Fedko, I. O., Hottenga, J. J., Willemsen, G., Bartels, M., Boomsma, D. I. & Vink, J. M., 1 Jan 2018, In : Drug and Alcohol Dependence. 183, p. 7-12 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Dec 2018, In : Nature Genetics. 50, 12, p. 1755-1755 1 p.

Research output: Contribution to JournalErratumAcademic

Selective maternal seeding and environment shape the human gut microbiome

Korpela, K., Costea, P., Coelho, L. P., Kandels-Lewis, S., Willemsen, G., Boomsma, D. I., Segata, N. & Bork, P., 1 Apr 2018, In : Genome Research. 28, 4, p. 561-568 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Testing familial transmission of smoking with two different research designs

Treur, J. L., Verweij, K. J. H., Abdellaoui, A., Fedko, I. O., de Zeeuw, E. L., Ehli, E. A., Davies, G. E., Hottenga, J. J., Willemsen, G., Boomsma, D. I. & Vink, J. M., 7 Jun 2018, In : Nicotine and Tobacco Research. 20, 7, p. 836-842 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2019

A Genetic Investigation of the Well-Being Spectrum

Baselmans, B. M. L., van de Weijer, M. P., Abdellaoui, A., Vink, J. M., Hottenga, J. J., Willemsen, G., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Bartels, M., 15 May 2019, In : Behavior Genetics. 49, 3, p. 286-297 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies

Doering, S., Lichtenstein, P., Gillberg, C., Boomsma, D. I., Van Beijsterveldt, T. C. E. M., Ligthart, L., Willemsen, G., De Geus, E., Middeldorp, C. M., Bartels, M., Kuja-Halkola, R. & Lundström, S., 14 Nov 2019, In : BMC Psychiatry. 19, 1, p. 1-11 11 p., 363.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Association between rs1051730 and smoking during pregnancy in Dutch women

Mbarek, H., van Beijsterveldt, C. E. M., Hottenga, J. J., Dolan, C. V., Boomsma, D. I., Willemsen, G. & Vink, J. M., Jun 2019, In : Nicotine and Tobacco Research. 21, 6, p. 835-840 6 p., ntx267.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B., Jansen, R. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Associations between Loneliness and Personality are Mostly Driven by a Genetic Association with Neuroticism

Abdellaoui, A., Chen, H-Y., Willemsen, G., Ehli, E. A., Davies, G. E., Verweij, K. J. H., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Cacioppo, J. T., Apr 2019, In : Journal of Personality. 87, 2, p. 386-397 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

23Andme Research Team & HUNT All-In Psychiatry, Feb 2019, In : Nature Genetics. 51, 2, p. 237-244 8 p.

Research output: Contribution to JournalLetterAcademicpeer-review

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Sullivan, P., 11 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Cohabitation is associated with a greater resemblance in gut microbiota which can impact cardiometabolic and inflammatory risk

Finnicum, C. T., Beck, J. J., Dolan, C. V., Davis, C., Willemsen, G., Ehli, E. A., Boomsma, D. I., Davies, G. E. & de Geus, E. J. C., 22 Oct 2019, In : BMC Microbiology. 19, 1, p. 1-10 10 p., 230.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetic Vulnerability for Smoking and Cannabis Use: Associations With E-Cigarette and Water Pipe Use

International Cannabis Consortium, 21 May 2019, In : Nicotine and Tobacco Research. 21, 6, p. 723-730 8 p., nty150.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium, 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes

Chen, J., Loukola, A., Gillespie, N. A., Peterson, R., Jia, P., Riley, B., Maes, H., Dick, D. M., Kendler, K. S., Damaj, M. I., Miles, M. F., Zhao, Z., Li, M. D., Vink, J. M., Minica, C. C., Willemsen, G., Boomsma, D. I., Qaiser, B., Madden, P. A. F., Korhonen, T. & 26 others, Jousilahti, P., Hällfors, J., Gelernter, J., Kranzler, H. R., Sherva, R., Farrer, L., Maher, B., Vanyukov, M., Taylor, M., Ware, J. J., Munafò, M. R., Lutz, S. M., Hokanson, J. E., Gu, F., Landi, M. T., Caporaso, N. E., Hancock, D. B., Gaddis, N. C., Baker, T. B., Bierut, L. J., Johnson, E. O., Chenoweth, M., Lerman, C., Tyndale, R., Kaprio, J. & Chen, X., 11 Jul 2019, In : Nicotine and Tobacco Research.

Research output: Contribution to JournalArticleAcademicpeer-review

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23Andme Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

EGG Consortium, 1 May 2019, In : Nature Genetics. 51, 5, p. 804-814 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Küpers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C. V., Allard, C., Just, A. C., Bakulski, K. M., Holloway, J. W. & 107 others, Everson, T. M., Xu, C. J., Huang, R. C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F. I., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M. R., Bergström, A., Örtqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Håberg, S. E., Sørensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I. V., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D. I., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melén, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M. F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Davey Smith, G., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 23 Apr 2019, In : Nature Communications. 10, p. 1-11 11 p., 1893.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

van der Spek, A., Broer, L., Draisma, H. H. M., Pool, R., Albrecht, E., Beekman, M., Mangino, M., Raag, M., Nyholt, D. R., Dharuri, H. K., Codd, V., Amin, N., de Geus, E. J. C., Deelen, J., Demirkan, A., Yet, I., Fischer, K., Haller, T., Henders, A. K., Isaacs, A. & 19 others, Medland, S. E., Montgomery, G. W., Mooijaart, S. P., Strauch, K., Suchiman, H. E. D., Vaarhorst, A. A. M., van Heemst, D., Wang-Sattler, R., Whitfield, J. B., Willemsen, G., Wright, M. J., Martin, N. G., Samani, N. J., Metspalu, A., Eline Slagboom, P., Spector, T. D., Boomsma, D. I., van Duijn, C. M. & Gieger, C., 12 Aug 2019, In : Scientific Reports. 9, 1, p. 11623 11623.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Multivariate genome-wide analyses of the well-being spectrum

BIOS Consortium, Mar 2019, In : Nature Genetics. 51, 3, p. 445-451 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Parental Education and Genetics of BMI from Infancy to Old Age: A Pooled Analysis of 29 Twin Cohorts

Silventoinen, K., Jelenkovic, A., Latvala, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Aaltonen, S., Piirtola, M., Freitas, D. L., Maia, J. A., Öncel, S. Y., Aliev, F., Ji, F., Ning, F., Pang, Z., Rebato, E., Saudino, K. J., Cutler, T. L. & 53 others, Hopper, J. L., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Cozen, W., Hwang, A. E., Mack, T. M., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Nelson, T. L., Whitfield, K. E., Sung, J., Kim, J., Lee, J., Lee, S., Llewellyn, C. H., Fisher, A., Medda, E., Nisticò, L., Toccaceli, V., Baker, L. A., Tuvblad, C., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Harris, J. R., Nilsen, T. S., Harden, K. P., Tucker-Drob, E. M., Franz, C. E., Kremen, W. S., Lyons, M. J., Lichtenstein, P., Jeong, H. U., Hur, Y. M., Boomsma, D. I., Sørensen, T. I. A. & Kaprio, J., 1 May 2019, In : Obesity. 27, 5, p. 855-865 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review