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  • A.H.M. Willemsen
2019

Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness

23Andme Research Team, 15 Nov 2019, In : Human Molecular Genetics. 28, 22, p. 3853-3865 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Skewed X-inactivation is common in the general female population

Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Willemsen, G. & BIOS Consortium, Mar 2019, In : European Journal of Human Genetics. 27, 3, p. 455-465 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins

Silventoinen, K., Jelenkovic, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Bogl, L. H., Freitas, D. L., Maia, J. A., Hjelmborg, J. V. B., Aaltonen, S., Piirtola, M., Latvala, A., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Ji, F., Ning, F., Pang, Z. & 118 others, Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Martin, N. G., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A., Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Tarnoki, A. D., Tarnoki, D. L., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Medda, E., Nisticò, L., Toccaceli, V., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Jeong, H-U., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Gao, W., Yu, C., Li, L., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E. M., Christensen, K., Skytthe, A., Kyvik, K. O., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Silberg, J. L., Maes, H. H., Cutler, T. L., Hopper, J. L., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Ullemar, V., Almqvist, C., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Rasmussen, F., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Harris, J. R., Sung, J., Park, H. A., Lee, J., Lee, S. J., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Llewellyn, C. H., Fisher, A., Rebato, E., Busjahn, A., Tomizawa, R., Inui, F., Watanabe, M., Honda, C., Sakai, N., Hur, Y-M., Sørensen, T. I. A., Boomsma, D. I. & Kaprio, J., Dec 2019, In : Twin research and human genetics : the official journal of the International Society for Twin Studies. 22, 6, p. 800-808 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

EArly Genetics Lifecourse Epidemiology (EAGLE) consortium & Early Growth Genetics (EGG) Consortium, Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Posthuma, D., 1 Nov 2019, In : Biological Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Twin Family Registries Worldwide: An Important Resource for Scientific Research

Hur, Y. M., Bogl, L. H., Ordoñana, J. R., Taylor, J., Hart, S. A., Tuvblad, C., Ystrom, E., Dalgård, C., Skytthe, A. & Willemsen, G., Dec 2019, In : Twin Research and Human Genetics. 22, 6, p. 427-437 11 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access

Validated inference of smoking habits from blood with a finite DNA methylation marker set

BIOS Consortium, Nov 2019, In : European Journal of Epidemiology. 34, 11, p. 1055-1074 20 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene

The Genome of the Netherlands consortium, 10 Dec 2019, In : Scientific Reports. 9, 1, p. 1-9 9 p., 18758.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2020

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Nivard, M., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C. & W J H Penninx, B., 8 May 2020, In : Nature Communications. 11, 1, p. 2301

Research output: Contribution to JournalArticleAcademicpeer-review

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Beekman, A. F. T., Jansen, R., Milaneschi, Y., Peyrot, W. J., Smit, J. H., W J H Penninx, B. & Posthuma, D., 16 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Posthuma, D. & Willemsen, G., 1 Mar 2020, In : Biological Psychiatry. 87, 5, p. 419-430 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetic and environmental influences on human height from infancy through adulthood at different levels of parental education

Jelenkovic, A., Sund, R., Yokoyama, Y., Latvala, A., Sugawara, M., Tanaka, M., Matsumoto, S., Freitas, D. L., Maia, J. A., Knafo-Noam, A., Mankuta, D., Abramson, L., Ji, F., Ning, F., Pang, Z., Rebato, E., Saudino, K. J., Cutler, T. L., Hopper, J. L., Ullemar, V. & 53 others, Almqvist, C., Magnusson, P. K. E., Cozen, W., Hwang, A. E., Mack, T. M., Nelson, T. L., Whitfield, K. E., Sung, J., Kim, J., Lee, J., Lee, S., Llewellyn, C. H., Fisher, A., Medda, E., Nisticò, L., Toccaceli, V., Baker, L. A., Tuvblad, C., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Burt, S. A., Klump, K. L., Silberg, J. L., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Harris, J. R., Brandt, I., Nilsen, T. S., Harden, K. P., Tucker-Drob, E. M., Franz, C. E., Kremen, W. S., Lyons, M. J., Lichtenstein, P., Bartels, M., Beijsterveldt, C. E. M. V., Willemsen, G., Öncel, S. Y., Aliev, F., Jeong, H-U., Hur, Y-M., Turkheimer, E., Boomsma, D. I., Sørensen, T. I. A., Kaprio, J. & Silventoinen, K., 14 May 2020, In : Scientific Reports. 10, 1, p. 7974

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

Li, C., Stoma, S., Lotta, L. A., Warner, S., Albrecht, E., Allione, A., Arp, P. P., Broer, L., Buxton, J. L., Da Silva Couto Alves, A., Deelen, J., Fedko, I. O., Gordon, S. D., Jiang, T., Karlsson, R., Kerrison, N., Loe, T. K., Mangino, M., Milaneschi, Y., Miraglio, B. & 76 others, Pervjakova, N., Russo, A., Surakka, I., van der Spek, A., Verhoeven, J. E., Amin, N., Beekman, M., Blakemore, A. I., Canzian, F., Hamby, S. E., Hottenga, J-J., Jones, P. D., Jousilahti, P., Mägi, R., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Perola, M., Pietiläinen, K. H., Salomaa, V., Sillanpää, E., Suchiman, H. E., van Heemst, D., Willemsen, G., Agudo, A., Boeing, H., Boomsma, D. I., Chirlaque, M-D., Fagherazzi, G., Ferrari, P., Franks, P., Gieger, C., Eriksson, J. G., Gunter, M., Hägg, S., Hovatta, I., Imaz, L., Kaprio, J., Kaaks, R., Key, T., Krogh, V., Martin, N. G., Melander, O., Metspalu, A., Moreno, C., Onland-Moret, N. C., Nilsson, P., Ong, K. K., Overvad, K., Palli, D., Panico, S., Pedersen, N. L., Penninx, B. W. J. H., Quirós, J. R., Jarvelin, M. R., Rodríguez-Barranco, M., Scott, R. A., Severi, G., Slagboom, P. E., Spector, T. D., Tjonneland, A., Trichopoulou, A., Tumino, R., Uitterlinden, A. G., van der Schouw, Y. T., van Duijn, C. M., Weiderpass, E., Denchi, E. L., Matullo, G., Butterworth, A. S., Danesh, J., Samani, N. J., Wareham, N. J., Nelson, C. P., Langenberg, C. & Codd, V., 5 Mar 2020, In : American Journal of Human Genetics. 106, 3, p. 389-404 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Beekman, A. T. F., Jansen, R., Milaneschi, Y., Smit, J. H., W J H Penninx, B. & Posthuma, D., 23 Jan 2020, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

BBMRI Metabolomics Consortium, 7 Jan 2020, In : Nature Communications. 11, 1, p. 39 39.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

Liu, J., Lahousse, L., Nivard, M. G., Bot, M., Chen, L., van Klinken, J. B., Thesing, C. S., Beekman, M., van den Akker, E. B., Slieker, R. C., Waterham, E., van der Kallen, C. J. H., de Boer, I., Li-Gao, R., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L. J. M., Murad, S. D. & 29 others, Uitterlinden, A. G., Willemsen, G., Pool, R., Milaneschi, Y., van Heemst, D., Suchiman, H. E. D., Rutters, F., Elders, P. J. M., Beulens, J. W. J., van der Heijden, A. A. W. A., van Greevenbroek, M. M. J., Arts, I. C. W., Onderwater, G. L. J., van den Maagdenberg, A. M. J. M., Mook-Kanamori, D. O., Hankemeier, T., Terwindt, G. M., Stehouwer, C. D. A., Geleijnse, J. M., 't Hart, L. M., Slagboom, P. E., van Dijk, K. W., Zhernakova, A., Fu, J., Penninx, B. W. J. H., Boomsma, D. I., Demirkan, A., Stricker, B. H. C. & van Duijn, C. M., Jan 2020, In : Nature Medicine. 26, 1, p. 110-117 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Substance use: Interplay between polygenic risk and neighborhood environment

Pasman, J. A., Verweij, K. J. H., Abdellaoui, A., Hottenga, J. J., Fedko, I. O., Willemsen, G., Boomsma, D. I. & Vink, J. M., 28 Feb 2020, In : Drug and Alcohol Dependence. 209, p. 107948 107948.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access