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  • A.H.M. Willemsen
2011

A 3p26-3p25 Genetic Linkage Finding for DSM-IV Major Depression in Heavy Smoking Families

Pergadia, M. L., Glowinski, A. L., Wray, N. R., Agrawal, A., Saccone, S. F., Loukola, A., Broms, U., Korhonen, T., Penninx, B. W. J. H., Grant, J. D., Nelson, E. C., Henders, A. K., Schrage, A. J., Chou, Y-L., Keskitalo-Vuokko, K., Zhu, Q., Gordon, S. D., Vink, J. M., de Geus, E. J. C., Macgregor, S. & 11 others, Liu, J. Z., Willemsen, G., Medland, S. E., Boomsma, D. I., Montgomery, GW., Rice, J. P., Goate, A. M., Heath, A. C., Kaprio, J., Martin, N. G. & Madden, P. A. F., 2011, In : American Journal of Psychiatry. 168, 8, p. 848-852

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females

Klok, M. D., Giltay, E. J., van der Does, A., Geleijnse, J. M., Antypa, N., Penninx, B. W. J. H., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., van Leeuwen, N., Zitman, F. G., de Kloet, E. R. & DeRijk, R. H., 2011, In : Translational Psychiatry. 1, p. 1-8 e62.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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ADHD in Dutch adults: heritability and linkage study

Savyuk, V., Hottenga, J. J., Slagboom, P. E., Distel, M. A., de Geus, E. J. C., Willemsen, G. & Boomsma, D. I., 2011, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156, 3, p. 352-362

Research output: Contribution to JournalArticleAcademicpeer-review

Adolescent personality profiles, neighborhood income, and young adult alcohol use: A longitudinal study

Ayer, L., Rettew, D., Althoff, R. R., Willemsen, G., Ligthart, L., Hudziak, J. J. & Boomsma, D. I., 2011, In : Addictive Behaviors. 36, 12, p. 1301-1304

Research output: Contribution to JournalArticleAcademicpeer-review

A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol

Surakka, I., Isaacs, A., Karssen, L. C., Laurila, P. P. P., Middelberg, R. P. S., Tikkanen, E., Ried, J. S., Lamina, C., Mangino, M., Igl, W., Hottenga, J. J., Lagou, V., van der Harst, P., Mateo Leach, I., Esko, T., Kutalik, Z., Wainwright, N. W., Struchalin, M. V., Sarin, A. P., Kangas, A. J. & 57 others, Viikari, J. S., Perola, M., Rantanen, T., Petersen, A. K., Soininen, P., Johansson, Å., Soranzo, N., Heath, A. C., Papamarkou, T., Prokopenko, I., Tönjes, A., Kronenberg, F., Döring, A., Rivadeneira, F., Montgomery, GW., Whitfield, J. B., Kähönen, M., Lehtimäki, T., Freimer, N. B., Willemsen, G., de Geus, E. J. C., Palotie, A., Sandhu, M. S., Waterworth, D., Metspalu, A., Stumvoll, M., Uitterlinden, A. G., Navis, G., Wijmenga, C., Wolffenbuttel, B. H. R., Taskinen, M. R., Ala-Korpela, M., Kaprio, J., Kyvik, K. O., Boomsma, D. I., Pedersen, N. L., Gyllensten, U., Wilson, J. F., Rudan, I., Campbell, H., Pramstaller, P. P., Spector, T. D., Witteman, J. C. M., Eriksson, J. G., Salomaa, V., Oostra, B. A., Raitakari, O. T., Wichmann, H. E., Gieger, C., Järvelin, M. J., Martin, N. G., Hofman, A., McCarthy, M. I., Peltonen, L., van Duijn, C. M., Aulchenko, Y. S. & Ripatti, S., 2011, In : PLoS Genetics. 7, 10, e1002333.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Clustering of medication use in twin families from the NTR Biobank

Willemsen, G., de Geus, E. J. C., van Bruggen, A. & Boomsma, D. I., 2011, In : Behavior Genetics. 41, 6, p. 941-942

Research output: Contribution to JournalMeeting AbstractOther research output

Open Access
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Epigenetic discordance in young, middle aged and old monozygotic twin pairs

Talens, R. P., Christensen, K., Putter, H., Willemsen, G., Christiansen, L., Kremer, D., Suchiman, H. E. D., Slagboom, P. E., Boomsma, D. I. & Heijmans, B. T., 2011.

Research output: Contribution to ConferencePosterOther research output

Exercise Participation in Adolescents and Their Parents: Evidence for Genetic and Generation Specific Environmental Effects

de Moor, M. H. M., Willemsen, G., Rebollo Mesa, I., Stubbe, J. H., de Geus, E. J. C. & Boomsma, D. I., 2011, In : Behavior Genetics. 41, 2, p. 211-222

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Genetic architecture of circulating lipid levels

Demirkan, A., Amin, A., Isaacs, A., Jarvelin, M-R., Whitfield, J. B., Wichmann, H-E., Ohm Kyvik, K., Rudan, I., Gieger, C., Hicks, A. A., Johansson, A., Hottenga, J. J., Smith, J. J., Wild, S. H., Pedersen, N. L., Willemsen, G., Mangino, M., Hayward, C., Uitterlinden, A. G., Hofman, A. & 26 others, Witteman, J., Montgomery, GW., Pietilainen, K. H., Rantanen, T., Kaprio, J., Döring, A., Pramstaller, P. P., Gyllensten, U., de Geus, E. J. C., Penninx, B. W. J. H., Wilson, J. F., Rivadeneira, F., Magnusson, P. K. E., Boomsma, D. I., Spector, T. D., Campbell, H., Hoehne, B., Martin, N. G., Oostra, B. A., McCarthy, M., Peltonen, L., Aulchenko, Y. S., Visscher, P. M., Ripatti, S., Janssens, A. C. J. W. & van Duijn, C. M., 2011, In : European Journal of Human Genetics. 19, 7, p. 813-819

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

Demirkan, A., Penninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlinden, A. G., Hottenga, J. J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. & 1 others, Middeldorp, C. M., 2011, In : Molecular Psychiatry. 16, 7, p. 773-783

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

Speliotes, E. K., Yerges-Armstrong, L. M., Wu, J., Hernaez, R., Kim, L. J., Palmer, C. D., Gudnason, V., Eiriksdottir, G., Garcia, M. E., Launer, L. J., Nalls, M. A., Clark, J. M., Mitchell, B. D., Shuldiner, A. R., Butler, J. L., Tomas, M., Hoffmann, U., Hwang, S. J., Massaro, J. M., O'Donnell, C. J. & 19 others, Sahani, D. V., Salomaa, V., Schadt, E. E., Schwartz, S. M., Siscovick, D. S., Posthuma, D., Voight, B. F., Carr, J. J., Feitosa, M. F., Harris, T. B., Fox, C. S., Smith, A. V., Kao, W. H. L., Hottenga, J. J., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Hirschhorn, J. N. & Borecki, I. B., 2011, In : PLoS Genetics. 7, 3, e1001324.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

Schumann, G., Coin, L. J. M., Lourdusamy, A., Charoen, P., Berger, K. H., Stacey, D., Desrivières, S., Aliev, F. A., Khan, A. A., Amin, N., Aulchenko, Y. S., Bakalkin, G., Bakker, S. J., Balkau, B., Beulens, J. W., Bilbao, A., de Boer, R. A., Beury, D., Bots, M. L., Breetvelt, E. J. & 80 others, Cauchi, S., Cavalcanti-Proença, C., Chambers, J. C., Clarke, T. K., Dahmen, N., de Geus, E. J. C., Dick, D., Duccia, F., Easton, A., Edenberg, H. J., Esk, T., Fernández-Medarde, A., Foroud, T., Freimer, N. B., Girault, J. A., Grobbee, D. E., Guarreray, S., Gudbjartsson, D. F., Hartikainen, A-L., Heath, A. C., Hesselbrock, V., Hofman, A., Hottenga, J. J., Isohanni, M., Kaprio, J., Khaw, K. T., Kuehnel, B., Laitinen, J., Lobbens, S., Luan, J., Mangino, M., Maroteau, M., Oostra, B. A., O’Reilly, P. F., Penninx, B. W. J. H., Pouta, A., Prokopenko, I., Ricceri, F., Santos, E., Smit, J. H., Soranzo, N., Stumvoll, M., Surakka, I., Thorgeirsson, T. E., Thorsteinsdottir, U., Troakes, C., Tyrfingsson, T., Tönjes, A., Uiterwaal, C. S., Uitterlinden, A. G., van der Harst, P., van der Schouw, Y. T., Staehlin, O., Vogelzangs, N., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D., Whitfield, J. B., Wichmann, H. E., Willemsen, G., Witteman, J. C., Martin, N. G., Metspalu, A., Scott, J., Spector, T. D., Loos, R. J., Boomsma, D. I., Mooser, V., Peltonen, L., Stefansson, K., van Duijn, C. M., Vineis, P., Sommer, W. H., Kooner, J. S., Spanagel, R., Heberlein, U. A., Numans, M. E., Jarvelin, M-R. & Elliott, P., 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 17, p. 7119-7124

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

Strawbridge, R. J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J. R., Bouatia-Naji, N., Dimas, A. S., Nica, A., Wheeler, E., Chen, H., Voight, B. F., Taneera, J., Kanoni, S., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Forsen, T. J. & 25 others, Clarke, R., Franzosi, M. G., Seedorf, U., Watkins, H., Froguel, P., Johnson, P., Deloukas, P., Collins, F. S., Laakso, M., Dermitzakis, E. T., Boehnke, M., McCarthy, M. I., Wareham, N. J., Groop, L., Pattou, F., Gloyn, A. L., Dedoussis, G. V., Lyssenko, V., Meigs, J. B., Barroso, I., Watanabe, R. M., Ingelsson, E., Langenberg, C., Hamsten, A. & Florez, J. C., 2011, In : Diabetes. 60, 10, p. 2624-2634

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Chambers, J. C., Zhang, W., Sehmi, J., Li, X., Wass, M. N., van der Harst, P., Holm, H., Sanna, S., Kavousi, M., Baumeister, S. E., Hottenga, J. J., Speliotes, E. K., de Geus, E. J. C., Martin, N. G., Montgomery, G. W., Penninx, B. W. J. H., Prokopenko, I., Spector, T. D., Uitterlinden, A. G., Willemsen, G. & 16 others, Abecasis, G. R., Boomsma, D. I., van Duijn, C. M., Snieder, H., Whitfield, J. B., Witteman, J. C. M., Fox, C. S., Ala-Korpela, M., Stefansson, K., Vollenweider, P., Völzke, H., Schadt, E. E., Scott, J., Jarvelin, M. R., Elliot, P. & Kooner, J. S., 2011, In : Nature Genetics. 43, 11, p. 1131-1140

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Wain, L. V., Verwoert, G. C., O'Reilly, P. F., Shi, G., Johnson, T., Johnson, A. D., Bochud, M., Rice, K. M., Henneman, P., Smith, A. V., Ehret, G. B., Amin, N., Larson, M. G., Mooser, V., Hadley, D., Dörr, M., Bis, J. C., Aspelund, T., Esko, T., Janssens, A. C. & 42 others, Zhao, J. H., Heath, S., Laan, M., Fu, J., Pistis, G., Luan, J., Arora, P., Hottenga, J. J., Rivadeneira, F., Sijbrands, E. J., Uitterlinden, A. G., Soranzo, N., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Spector, T. D., Snieder, H., Oostra, B. A., Metspalu, A., Launer, L., Rettig, R., Strachan, D. P., Beckmann, J. S., Witteman, J. C., Erdmann, J., van Dijk, K. W., Boerwinkle, E., Boehnke, M., Ridker, P. M., Jarvelin, M. R., Chakravarti, A., Abecasis, G. R., Gudnason, V., Newton-Cheh, C., Levy, D., Munroe, P. B., Psaty, B. M., Caulfield, M. J., Rao, D. C., Tobin, M. D., Elliott, P. & van Duijn, C. M., 2011, In : Nature Genetics. 43, 10, p. 1005-1012

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide complex trait analysis (gcta) for complex traits including major depressive disorder and smoking

Boomsma, D. I., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Lubke, G. H., 2011.

Research output: Contribution to ConferencePosterOther research output

Heritability of cardiac sympathetic control at rest and during stress and the contribution of the Gln27Glu beta-2-adrenergic receptor polymorphism

de Geus, E. J. C., Snieder, H., Kupper, H. M., Suchiman, H. E. D., Slagboom, P. E., Bartels, M., Willemsen, G. & Boomsma, D. I., 2011, In : Behavior Genetics. 41, 6, p. 899

Research output: Contribution to JournalMeeting AbstractOther research output

Open Access
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Heritability of problem drinking and the genetic overlap with personality in a general population sample

de Moor, M. H. M., Vink, K., van Beek, J. H. D. A., Geels, L. M., Bartels, M., de Geus, E. J. C., Willemsen, G. & Boomsma, D. I., 2011, In : Frontiers in Genetics. 2, p. 76

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

Ferreira, M. A. R., Matheson, M. C., Duffy, DL., Marks, G. B., Hui, J., Le Souëf, P., Danoy, P., Baltic, S., Nyholt, DR., Jenkins, M., Hayden, C., Willemsen, G., Ang, W., Kuokkanen, M., Beilby, J., Cheah, F., de Geus, E. J. C., Vedantam, S., Salomaa, V., Madden, P. A. & 19 others, Heath, A. C., Hopper, J. L., Visscher, P. M., Musk, B., Leeder, S. R., Jarvelin, M-R., Pennel, C., Boomsma, D. I., Hirschhorn, J. N., Walters, H., Martin, N. G., James, A., Jones, G., Abramson, M. J., Robertson, C. F., Dharmage, S. C., Brown, M. A., Montgomery, GW. & Thompson, P. J., 2011, In : Lancet. 378, 9795, p. 1006-1014

Research output: Contribution to JournalArticleAcademicpeer-review

Life events and borderline personality features: the influence of gene–environment interaction and gene–environment correlation

Distel, M. A., Middeldorp, C. M., Trull, T. J., Derom, C. A., Willemsen, G. & Boomsma, D. I., 2011, In : Psychological Medicine. 41, 4, p. 849-860

Research output: Contribution to JournalArticleAcademicpeer-review

LPAR1 and ITGA4 Regulate Peripheral Blood Monocyte Counts

Maugeri, N., Powell, J. E., 't Hoen, P. A. C., de Geus, E. J. C., Willemsen, G., Kattenberg, V. M., Henders, A. K., Wallace, L., Penninx, B. W. J. H., Hottenga, J. J., Medland, S. E., Savyuk, V., Martin, N. G., Visscher, P. M., van Ommen, G. J. B., Frazer, I. H., Boomsma, D. I., Montgomery, GW. & Ferreira, M. A. R., 2011, In : Human Mutation. 32, 8, p. 873-876

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder

Liu, Y., Blackwood, D. H., Caesar, S., de Geus, E. J. C., Farmer, A., Ferreira, M. A. R., Ferrier, I. N., Fraser, C., Gordon-Smith, K., Green, E. K., Grozeva, D., Gurling, H. M., Hamshere, M. L., Heutink, P., Holmans, P. A., Hoogendijk, W. J. G., Hottenga, J. J., Jones, L., Jones, I. R., Kirov, G. & 24 others, Lin, D., McGuffin, P., Moskvina, V., Nolen, W. A., Perlis, R. H., Posthuma, D., Scolnick, E. M., Smit, A. B., Smit, J. H., Smoller, J. W., St Clair, D., van Dyck, R., Verhage, M., Willemsen, G., Young, A. H., Zandbelt, T., Boomsma, D. I., Craddock, N., O’Donovan, M. C., Owen, M. J., Penninx, B. W. J. H., Purcell, S., Sklar, P. & Sullivan, P. F., 2011, In : Molecular Psychiatry. 16, 1, p. 2-4

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analysis of genome-wide association for migraine in six population-based European cohorts

Ligthart, L., de Vries, B., Smith, A. V., Arfan Ikram, M., Amin, N., Hottenga, J. J., Koelewijn, S. C., Kattenberg, V. M., de Moor, M. H. M., Janssens, A. J. W., Aulchenko, Y. S., Oostra, B. A., de Geus, E. J. C., Smit, J. H., Zitman, F. G., Uitterlinden, A. G., Hofman, A., Willemsen, G., Nyholt, DR., Montgomery, G. W. & 9 others, Terwindt, G. M., Gudnason, V., Penninx, B. W. J. H., Breteler, M., Ferrari, M. D., Launer, L. J., van Duijn, C. M., van den Maagdenberg, A. M. J. M. & Boomsma, D. I., 2011, In : European Journal of Human Genetics. 19, 8, p. 901-907

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with Excitement-Seeking

Terracciano, A., Esko, T., Sutin, A. R., de Moor, M. H. M., Meirelles, O., Zhu, G., Tanaka, T., Giegling, I., Nutile, T., Realo, A., Allik, J., Hansell, N. K., Wright, M. J., Montgomery, G. W., Willemsen, G., Hottenga, J. J., Friedl, M., Ruggiero, D., Sorice, R., Sanna, S. & 17 others, Deiana, B., Cucca, F., Krueger, R. F., Lahti, A., Luciano, M., Smoller, J. W., van Duijn, C. M., Abecasis, G. R., Boomsma, D. I., Ciullo, M., Costa, P. T., Ferrucci, L., Martin, N. G., Metspalu, A., Rujescu, D., Schlessinger, D. & Uda, M., 2011, In : Translational Psychiatry. 1, e49

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels

Dehghan, A., Dupuis, J., Barbalic, M., Bis, J. C., Eiriksdottir, G., Lu, C., Pellikka, N., Wallaschofski, H., Kettunen, J., Henneman, P., Baumert, J., Strachan, D. P., Fuchsberger, C., Vitart, V., Wilson, J. F., Paré, G., Naitza, S., Rudock, M. E., Surakka, I., de Geus, E. J. C. & 79 others, Alizadeh, BZ., Guralnik, J., Shuldiner, A., Tanaka, T., Zee, R. Y. L., Schnabel, R. B., Nambi, V., Kavousi, M., Ripatti, S., Nauck, M., Smith, N. L., Smith, A. V., Sundvall, J., Scheet, P., Liu, Y., Ruokonen, A., Rose, L. M., Larson, M. G., Hoogeveen, R. C., Freimer, N. B., Teumer, A., Tracy, R. P., Launer, L. J., Buring, J. E., Yamamoto, J. F., Folsom, A. R., Sijbrands, E. J. G., Pankow, J., Elliott, P., Keaney, J. F., Sun, W., Sarin, A-P., Fontes, J. D., Badola, S., Astor, B. C., Hofman, A., Pouta, A., Werdan, K., Greiser, K. H., Meyer zu Schwabedissen, H. E., Thiery, J., Jamshidi, Y., Nolte, I. M., Soranzo, N., Spector, T. D., Völzke, H., Aspelund, T., Young, L., Siscovick, D. S., Rotter, J. I., Schlessinger, D., Rudan, I., Hicks, A. A., Penninx, B. W. J. H., Gieger, C., Willemsen, G., Harris, T. B., Uitterlinden, A. G., Järvelin, M. J., Rice, K., Salomaa, V., Boerwinkle, E., Ferrucci, L., Snieder, H., Boomsma, D. I., Hayward, C., Pramstaller, P. P., van Duijn, C. M., Peltonen, L., Psaty, B. M., Gudnason, V., Ridker, P. M., Homuth, G., Koenig, W., Ballantyne, C. M., Witteman, J. C. M., Benjamin, E. J., Perola, M. & Chasman, D. I., 2011, In : Circulation. 123, 7, p. 731-738

Research output: Contribution to JournalArticleAcademicpeer-review

New gene functions in megakaryopoiesis and platelet formation

Gieger, C., Radhakrishnan, A., Cvejic, A., Tang, W., Porcu, E., Pistis, G., Serbanovic-Canic, J., Elling, U., Goodall, A. H., Labrune, Y., Hottenga, J. J., de Geus, E. J. C., Montgomery, GW., Visscher, P. M., Willemsen, G., Boomsma, D. I., Martin, N. G., Spector, T. D., Prokopenko, I., Stemple, D. & 8 others, Toniolo, L., Wernisch, L., Sanna, S., Hicks, A. A., Rendon, A., Ferreira, M. A., Ouwehand, W. H. & Soranzo, N., 2011, In : Nature. 480, 7376, p. 201-208

Research output: Contribution to JournalArticleAcademicpeer-review

Nine-Year Stability of Type D Personality: Contributions of Genes and Environment

Kupper, H. M., Boomsma, D. I., de Geus, E. J. C., Denollet, J. & Willemsen, G., 2011, In : Psychosomatic Medicine. 73, 1, p. 75-82

Research output: Contribution to JournalArticleAcademicpeer-review

Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals

Kilpelaïnen, T. O., van den Hoed, M., Ong, K. K., Grøntved, A., Brage, S., Hottenga, J. J., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Jameson, K., Cooper, C., Khaw, K. T., Ekelund, U., Wareham, N. J. & Loos, R. J., 2011, In : The American Journal of Clinical Nutrition. 93, 4, p. 851-860

Research output: Contribution to JournalArticleAcademicpeer-review

Poor replication of candidate genes for major depressive disorder using genome-wide association data.

Bosker, F. J., Hartman, C. A., Nolte, I. M., Prins, B. P., Terpstra, P., Posthuma, D., van Veen, T., Willemsen, G., DeRijk, R. H., de Geus, E. J. C., Hoogendijk, W. J. G., Sullivan, P. F., Penninx, B. W. J. H., Boomsma, D. I., Snieder, H. & Nolen, W. A., 2011, In : Molecular Psychiatry. 16, 5, p. 516-532

Research output: Contribution to JournalArticleAcademicpeer-review

Qualitative and quantitative sex differences in genetic architecture for human phenotypes

Boomsma, D. I., Bartels, M., van Beijsterveldt, C. E. M., Distel, M. A., Smit, D. J. A., de Moor, M. H. M., Middeldorp, M., Ligthart, R. S. L., Willemsen, G., Hottenga, J. J., de Geus, E. J. C. & Vink, J. M., 2011, In : Behavior Genetics. 41, 6, p. 894-895

Research output: Contribution to JournalMeeting AbstractOther research output

Open Access
File

The association of heart rate variability at baseline and the pro-inflammatory state five years later

Neijts, M., Willemsen, G., Boomsma, D. I. & de Geus, E. J. C., 2011.

Research output: Contribution to ConferencePosterOther research output

The association of heart rate variability at baseline and the pro-inflammatory state five years later

Neijts, M., Willemsen, G., Boomsma, D. I. & de Geus, E. J. C., 2011.

Research output: Contribution to ConferencePosterOther research output

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

Middeldorp, C. M., de Moor, M. H. M., McGrath, L. M., Gordon, S. D., Blackwood, D. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J. C., Nyholt, DR., Tanaka, T., Esko, T., Madden, P. A. F., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S. & 41 others, Spinhoven, P., Hartman, C. A., Ripke, S., Sullivan, P. F., Realo, A., Allik, J., Heath, A. C., Pergadia, M. L., Agrawal, A., Lin, P., Grucza, R. A., Widen, E., Cousminer, D. L., Eriksson, J. G., Palotie, A., Barnett, J. H., Lee, P. H., Luciano, M., Tenesa, A., Davies, G., Lopez, L. M., Hansell, N. K., Medland, S. E., Ferrucci, L., Schlessinger, D., Montgomery, GW., Wright, M. J., Aulchenko, Y. S., Janssens, A. C. J. W., Oostra, B. A., Metspalu, A., Abecasis, G. R., Deary, I. J., Räikkönen, K., Bierut, L. J., Martin, N. G., Wray, N. R., van Duijn, C. M., Smoller, J. W., Penninx, B. W. J. H. & Boomsma, D. I., 2011, In : Translational Psychiatry. 1, e50.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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The heritability of beta cell function parameters in a mixed meal test design

Simonis-Bik, A. M. C., Boomsma, D. I., Dekker, J. M., Diamant, M., de Geus, E. J. C., Hart, L. M., Heine, R. J., Kramer, M. H. H., Maassen, J. A., Mari, A., Tura, A., Willemsen, G. & Eekhoff, E. M. W., 2011, In : Diabetologia. 54, 5, p. 1043-1051

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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The Lin28/let-7 axis regulates glucose metabolism

Zhu, H., Shyh-Chang, N., Segre, A. V., Shinoda, G., Shah, S. P., Einhorn, W. S., Takeuchi, A., Engreitz, J. M., Hagan, J. P., Kharas, M. G., Urbach, A., Thornton, J. E., Triboulet, R., Gregory, R. I., Hottenga, J. J., de Geus, E. J. C., Posthuma, D., Willemsen, G., Boomsma, D. I., Altshuler, D. & 1 others, Daley, G. Q., 2011, In : Cell. 147, 1, p. 81-94

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Underestimation of cardiac vagal control in regular exercisers by 24-hour heart rate variability recordings

van Lien, R., Goedhart, A. D., Kupper, H. M., Boomsma, D. I., Willemsen, G. & de Geus, E. J. C., 2011, In : International Journal of Psychophysiology. 81, 3, p. 169-176

Research output: Contribution to JournalArticleAcademicpeer-review

Variation in BMPR1B, TGFRB1 and BMPR2 and Control of Dizygotic Twinning

Luong, H. T. T., Chaplin, J., McRae, A. F., Medland, S. E., Willemsen, G., Nyholt, DR., Henders, A. K., Hoekstra, C., Duffy, DL., Martin, N. G., Boomsma, D. I., Montgomery, GW. & Painter, J. N., 2011, In : Twin Research and Human Genetics. 14, 5, p. 408-416

Research output: Contribution to JournalArticleAcademicpeer-review

2012

A Fine-Mapping Study of 7 Top Scoring Genes from a GWAS for Major Depressive Disorder

Verbeek, E. C., Bakker, I. M. C., Bevova, M. R., Bochdanovits, Z., Rizzu, P., Sondervan, D., Willemsen, G., de Geus, E. J. C., Smit, J. H., Penninx, B. W. J. H., Boomsma, D. I., Hoogendijk, W. J. G. & Heutink, P., 2012, In : PLoS ONE. 7, 5, p. e37384 e37384.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

Manning, A. K., Hivert, M. F., Scott, R. A., Grimsby, J. L., Bouatia-Naji, N., Chen, H., Rybin, D., Liu, C. T., Bielak, L. F., Prokopenko, I., Amin, N., Barnes, D., Cadby, G., Hottenga, J. J., Ingelsson, E., Boomsma, D. I., de Geus, E. J. C., Penninx, B. W. J. H., Willemsen, G., Wilson, J. F. & 14 others, Witteman, J. C. M., Wright, A. F., Yaghootkar, H., Zelenika, D., Zemunik, T., Zgaga, L., Wareham, N. J., McCarthy, M. I., Barroso, I., Watanabe, R. M., Florez, J. C., Dupuis, J., Meigs, J. B. & Langenberg, C., 2012, In : Nature Genetics. 44, 6, p. 659-669

Research output: Contribution to JournalArticleAcademicpeer-review

A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans

Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., Sandy An, S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M. & 11 others, Divers, J., Shriner, D., Adeyemo, A., Rotimi, C. N., Ng, M. C. Y., Langefeld, C. D., Freedman, B. I., Bowden, D. W., Posthuma, D., Penninx, B. W. J. H. & Sladek, R., 2012, In : PLoS ONE. 7, 1, p. e29202 e29202.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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A Genome-Wide Association Study of Monozygotic Twin-Pairs Suggests a Locus Related to Variability of Serum High-Density Lipoprotein Cholesterol

Surakka, I., Whitfield, J. B., Perola, M., Visscher, P. M., Montgomery, G. W., Falchi, M., Willemsen, G., de Geus, E. J. C., Magnusson, P. K. E., Christensen, K., Sørensen, T. I. A., Pietilainen, K. H., Rantanen, T., Silander, K., Widen, E., Muilu, J., Rahman, I., Liljedahl, U., Syvänen, A. C., Palotie, A. & 8 others, Kaprio, J., Kyvik, K. O., Pedersen, N. L., Boomsma, D. I., Spector, T. D., Martin, N. G., Ripatti, S. & Peltonen, L., 2012, In : Twin Research and Human Genetics. 15, 6, p. 691-699

Research output: Contribution to JournalArticleAcademicpeer-review

A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site

Nürnberg, S. T., Rendon, A., Smethurst, P. A., Paul, D. S., Voss, K., Thon, J. N., Lloyd-Jones, H., Sambrook, J. G., Tijssen, M. R., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Italiano Jr, J. E., Deloukas, P., Gottgens, B., Soranzo, N. & Ouwehand, W. H., 2012, In : Blood. 120, 24, p. 4859-4868

Research output: Contribution to JournalArticleAcademicpeer-review

Are parental personality traits a basis for mate selection?

McCrae, R. R., Willemsen, G. & Boomsma, D. I., 2012, In : Journal of Research in Personality. 46, 4, p. 455-457

Research output: Contribution to JournalArticleAcademicpeer-review

Borderline Personality Traits and Substance Use: Genetic Factors Underlie the Association with Smoking and Ever Use of Cannabis, but Not with High Alcohol Consumption

Distel, M. A., Trull, T. J., de Moor, M. H. M., Vink, J. M., Geels, L. M., van Beek, J. H. D. A., Bartels, M., Willemsen, G., Thiery, E., Derom, C. A., Neale, M. C. & Boomsma, D. I., 2012, In : Journal of Personality Disorders. 26, 6, p. 867-879

Research output: Contribution to JournalArticleAcademicpeer-review

Common variants at 12q15 and 12q24 are associated with infant head circumference

Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Boomsma, D. I., Hakonarson, H., Smith, G. D., Heinrich, J., Jarvelin, M-R. & Jaddoe, V. W. V., 2012, In : Nature Genetics. 44, 5, p. 532-538

Research output: Contribution to JournalArticleAcademicpeer-review

Common variants at 6q22 and 17q21 are associated with intracranial volume

Arfan Ikram, M., Fornage, M., Smith, A. V., Seshadri, S., Schmidt, R., Debette, S., Vrooman, H. A., Sigurdsson, S., Ropele, S., Taal, H. R., Mook-Kanamori, D. O., Coker, L. H., Longstreth, J. W. T., Niessen, W. J., DeStefano, A. L., Beiser, A., Zijdenbos, A. P., Struchalin, M., Jack, C. R., Rivadeneira, F. & 43 others, Uitterlinden, A. G., Knopman, D. S., Hartikainen, A-L., Pennell, C. E., Thiering, E., Steegers, E. A. P., Hakonarson, H., Heinrich, J., Palmer, L. J., Jarvelin, M-R., McCarthy, M. I., Grant, S. F. A., St Pourcain, B., Timpson, N. J., Smith, G. D., Sovio, U., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., Nalls, M. A., Au, R., Hofman, A., Gudnason, H., van der Lugt, A., Harris, T. B., Meeks, W. M., Vernooij, M. W., van Buchem, M. A., Catellier, D., Jaddoe, V. W. V., Gudnason, V., Windham, B. G., Wolf, P. A., van Duijn, C. M., Mosley, T. H., Schmidt, H., Launer, L. J., Breteler, M. M. B. & DeCarli, C. S., 2012, In : Nature Genetics. 44, 5, p. 539-544

Research output: Contribution to JournalArticleAcademicpeer-review

Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp

van Vliet-Ostaptchouk, J. V., van Haeften, T. W., Landman, G. W. D., Reiling, E., Kleefstra, N., Bilo, H. J. G., Klungel, O. H., de Boer, A., van Diemen, C. C., Wijmenga, C., Boezen, H. M., Dekker, J. M., van 't Riet, E., Nijpels, G., Welschen, L. M. C., Zavrelová, H., Bruin, E. J., Elbers, C. C., Bauer, F., Onland-Moret, N. C. & 14 others, van der Schouw, Y. T., Grobbee, D. E., Spijkerman, A. M. W., van der Aa, D. L., Bik-Simonis, A. M. C., Eekhoff, E. M. W., Diamant, M., Kramer, M. H. H., Boomsma, D. I., de Geus, E. J. C., Willemsen, G., Slagboom, P. E., Hofker, M. H. & Hart, L. M., 2012, In : PLoS ONE. 7, 3, e32148.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs

Talens, R. P., Christensen, K., Putter, H., Willemsen, G., Christiansen, L., Kremer, D., Suchiman, H. E. D., Slagboom, P. E., Boomsma, D. I. & Heijmans, B. T., 2012, In : Aging Cell. 11, 4, p. 694-703

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms

Lubke, G. H., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Boomsma, D. I., 2012, In : Biological Psychiatry. 72, 8, p. 707-709

Research output: Contribution to JournalArticleAcademicpeer-review

FTO genotype is associated with phenotypic variability of body mass index

Yang, J., Loos, R. J., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Mägi, R., Waite, L., Smith, A. V., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., Huffman, J. E. & 151 others, Wang, S. R., Palmer, C., Esko, T., Fischer, K., Zhao, J. H., Demirkan, A., Isaacs, A., Feitosa, M. F., Luan, J., Heard-Costa, N. L., White, C., Jackson, A. U., Preuss, M., Ziegler, A., Eriksson, J., Kutalik, Z., Frau, F., Nolte, I. M., van Vliet-Ostaptchouk, J. V., Hottenga, J. J., Jacobs, K. B., Verweij, N., Goel, A., Medina-Gomez, C., Estrada, K., Bragg-Gresham, J. L., Sanna, S., Sidore, C., Tyrer, J., Teumer, A., Prokopenko, I., Mangino, M., Lindgren, C. M., Assimes, T. L., Shuldiner, A. R., Hui, J., Beilby, J. P., McArdle, W. L., Hall, P., Haritunians, T., Zgaga, L., Kolcic, I., Polasek, O., Zemunik, T., Oostra, B. A., Junttila, M. J., Grönberg, H., Schreiber, S., Peters, A., Hicks, A. A., Stephens, J., Foad, N. S., Laitinen, J., Pouta, A., Kaakinen, M., Willemsen, G., Vink, J. M., Wild, S. H., Navis, G., Asselbergs, F. W., Homuth, G., John, U., Iribarren, C., Harris, T., Launer, L. J., Gudnason, V., O'Connell, J. R., Boerwinkle, E., Cadby, G., Palmer, L. J., James, A. L., Musk, A. W., Ingelsson, E., Psaty, B. M., Beckmann, J. S., Waeber, G., Vollenweider, P., Hayward, C., Wright, A. F., Rudan, I., Groop, L. C., Metspalu, A., Thee Khaw, K., van Duijn, C. M., Borecki, I. B., Province, M. A., Wareham, N. J., Tardif, J. C., Huikuri, H. V., Cupples, L. A., Atwood, L. D., Fox, C. S., Boehnke, M., Collins, F. S., Mohlke, K. L., Erdmann, J., Schunkert, H., Hengstenberg, C., Stark, K., Lorentzon, M., Ohlsson, C., Cusi, D., Staessen, J. A., van der Klauw, M. M., Pramstaller, P. P., Kathiresan, S., Jolley, D. J., Ripatti, S., Jarvelin, M-R., de Geus, E. J. C., Boomsma, D. I., Penninx, B. W. J. H., Wilson, J. F., Campbell, H., Chanock, S. J., van der Harst, P., Hamsten, A., Watkins, H., Hofman, A., Witteman, J. C., Zillikens, M. C., Uitterlinden, A. G., Rivadeneira, F., Kiemeney, L. A., Vermeulen, S. H., Abecasis, G. R., Schlessinger, D., Schipf, S., Stumvoll, M., Tönjes, A., Spector, T. D., North, K. E., Lettre, G., McCarthy, M. I., Berndt, S. I., Heath, A. C., Madden, P. A. F., Nyholt, DR., Montgomery, G. W., Martin, N. G., McKnight, B., Strachan, D. P., Hill, W. G., Snieder, H., Ridker, P. M., Thorsteinsdottir, U., Stefansson, K., Frayling, T. M., Hirschhorn, J. N., Goddard, M. E. & Visscher, P. M., 2012, In : Nature. 490, 7419, p. 267-272

Research output: Contribution to JournalArticleAcademicpeer-review