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  • D.I. Boomsma
2017

Short telomere length is associated with impaired cognitive performance in European ancestry cohorts

Hägg, S., Zhan, Y., Karlsson, R., Gerritsen, L., Ploner, A., Lee, J-S., Broer, L., Deelen, J., Marioni, R. E., Wong, A., Lundquist, A., Zhu, G., Hansell, N. K., Sillanpää, E., Fedko, I. O., Amin, N. A., Beekman, M., Craen, A. J. M., Degerman, S., Harris, S. E. & 26 others, Kan, K-J., Martin-Ruiz, C., Montgomery, G. W., Adolfsson, A. N., Reynolds, C. A., Samani, N. J., Suchiman, H. E. D., Viljanen, A., von Zglinicki, T., Wright, M. J., Hottenga, J-J., Boomsma, D. I., Rantanen, T., Kaprio, J. A., Nyholt, D. R., Martin, N. G., Nyberg, L., Adolfsson, R., Kuh, D., Starr, J. M., Deary, I. J., Slagboom, P. E., van Duijn, C. M., Codd, V., Pedersen, N. L. & NeuroCHARGE Cognitive Working Group, 18 Apr 2017, In : Translational Psychiatry. 7, 4, p. e1100 e1100.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Bullying and Victimization: The Effect of Close Companionship

Veldkamp, S. A. M., van Bergen, E., de Zeeuw, E. L., van Beijsterveldt, C. E. M., Boomsma, D. I. & Bartels, M., Feb 2017, In : Twin Research and Human Genetics. 20, 1, p. 19-27 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

EGG Consortium, 1 May 2019, In : Nature Genetics. 51, 5, p. 804-814 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2018

Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts

Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y. M., Ullemar, V., Almqvist, C., Magnusson, P. K., Willemsen, G., Bartels, M., Beijsterveldt, C. E. V., Bogl, L. H., Pietiläinen, K. H., Vuoksimaa, E., Ji, F., Ning, F., Pang, Z., Nelson, T. L., Whitfield, K. E., Rebato, E., Llewellyn, C. H. & 30 others, Fisher, A., Bayasgalan, G., Narandalai, D., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Stazi, M. A., Fagnani, C., Brescianini, S., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Cutler, T. L., Hopper, J. L., Krueger, R. F., McGue, M., Pahlen, S., Craig, J. M., Saffery, R., Haworth, C. M., Plomin, R., Knafo-Noam, A., Mankuta, D., Abramson, L. & Boomsma, D. I., 19 Apr 2018, In : Scientific Reports. 8, 1, 6300.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

Linkage of health insurance data to the Netherlands Twin Register

van Grootheest, G., Ariel, A., Glasner, T., Verkerk, B., van Beijsterveldt, C. E. M., van der Laan, J., de Groot, M., Visser, S., Bakker, B. F. M. & Boomsma, D. I., 1 Mar 2017, In : International Journal of population Data Science. 1, 1, p. 28 1 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts

Silventoinen, K., Jelenkovic, A., Latvala, A., Sund, R., Yokoyama, Y., Ullemar, V., Almqvist, C., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Kandler, C., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Rebato, E., Stazi, M. A., Fagnani, C., Brescianini, S., Hur, Y-M. & 81 others, Jeong, H-U., Cutler, T. L., Hopper, J. L., Busjahn, A., Saudino, K. J., Ji, F., Ning, F., Pang, Z., Rose, R. J., Koskenvuo, M., Heikkilä, K., Cozen, W., Hwang, A. E., Mack, T. M., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Sung, J., Kim, J., Lee, J., Lee, S., Nelson, T. L., Whitfield, K. E., Tan, Q., Zhang, D., Llewellyn, C. H., Fisher, A., Burt, S. A., Klump, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Medland, S. E., Martin, N. G., Montgomery, G. W., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Corley, R. P., Huibregtse, B. M., Öncel, S. Y., Aliev, F., Krueger, R. F., McGue, M., Pahlen, S., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Silberg, J. L., Eaves, L. J., Maes, H. H., Harris, J. R., Brandt, I., Nilsen, T. S., Rasmussen, F., Tynelius, P., Baker, L. A., Tuvblad, C., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Gatz, M., Butler, D. A., Lichtenstein, P., Goldberg, J. H., Harden, K. P., Tucker-Drob, E. M., Duncan, G. E., Buchwald, D., Tarnoki, A. D., Tarnoki, D. L., Franz, C. E., Kremen, W. S., Lyons, M. J., Maia, J. A., Freitas, D. L., Turkheimer, E., Sørensen, T. I. A., Boomsma, D. I. & Kaprio, J., Oct 2017, In : Twin Research and Human Genetics. 20, 5, p. 395-405 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2018

An Extended Twin-Pedigree Study of Neuroticism in the Netherlands Twin Register

Boomsma, D. I., Helmer, Q., Nieuwboer, H. A., Hottenga, J. J., de Moor, M. H., van den Berg, S. M., Davies, G. E., Vink, J. M., Schouten, M. J., Dolan, C. V., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Ligthart, L. & de Geus, E. J., 1 Jan 2018, In : Behavior Genetics. 48, 1, p. 1-11

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T. M., McGrath, J., Hickie, I. B., Hansell, N. K., Wright, M. J., Gillespie, N. A., Forstner, A. J., Schulze, T. G., Wüst, S., Nöthen, M. M., Baumgartner, M. R., Walker, B. R., Crawford, A. A. & 12 others, Colodro-Conde, L., Medland, S. E., Martin, N. G., Rietschel, M., CORtisolNETwork (CORNET) Consortium, Abdellaoui, A., de Geus, E., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Willemsen, G. & Boomsma, D. I., 10 Nov 2017, In : Scientific Reports. 7, 1, p. 15351 15351.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Hinney, A., Kesselmeier, M., Jall, S., Volckmar, A-L., Föcker, M., Antel, J., Heid, I. M., Winkler, T. W., Grant, S. F. A., Guo, Y., Bergen, A. W., Kaye, W., Berrettini, W., Hakonarson, H., Herpertz-Dahlmann, B., de Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Egberts, K. M. & 19 others, Adan, R., Brandys, M., van Elburg, A., Boraska Perica, V., Franklin, C. S., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., GCAN, Hottenga, J. J., Willemsen, G., Boomsma, D. I., van Beijsterveldt, C. E. M., Middeldorp, C. M. & de Geus, E., Feb 2017, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2019

Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies

Doering, S., Lichtenstein, P., Gillberg, C., Boomsma, D. I., Van Beijsterveldt, T. C. E. M., Ligthart, L., Willemsen, G., De Geus, E., Middeldorp, C. M., Bartels, M., Kuja-Halkola, R. & Lundström, S., 14 Nov 2019, In : BMC Psychiatry. 19, 1, p. 1-11 11 p., 363.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

Genome-Wide Significance for PCLO as a Gene for Major Depressive Disorder

Mbarek, H., Milaneschi, Y., Hottenga, J-J., Ligthart, L., de Geus, E. J. C., Ehli, E. A., Willemsen, G., Davies, G. E., Smit, J. H., Boomsma, D. I. & Penninx, B. W. J. H., 1 Aug 2017, In : Twin Research and Human Genetics. 20, 4, p. 267-270 4 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2019

An Extended Twin-pedigree Study Of Voluntary Exercise Behavior In The Netherlands

de Geus, E. J. C., Helmer, Q., Boomsma, D. & van der Zee, M. D., Jun 2019, In : Medicine and Science in Sports and Exercise. 51, 6, p. 224-224

Research output: Contribution to JournalMeeting AbstractAcademic

2016

Genetic effects on source level evoked and induced oscillatory brain responses in a visual oddball task

Antonakakis, M., Zervakis, M., van Beijsterveldt, C. E. M., Boomsma, D. I., de Geus, E. J. C., Micheloyannis, S. & Smit, D. J. A., 2016, In : Biological Psychology. 114, p. 69-80

Research output: Contribution to JournalArticleAcademicpeer-review

2019

The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins

Silventoinen, K., Jelenkovic, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Bogl, L. H., Freitas, D. L., Maia, J. A., Hjelmborg, J. V. B., Aaltonen, S., Piirtola, M., Latvala, A., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Ji, F., Ning, F., Pang, Z. & 118 others, Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Martin, N. G., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A., Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Tarnoki, A. D., Tarnoki, D. L., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Medda, E., Nisticò, L., Toccaceli, V., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Jeong, H-U., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Gao, W., Yu, C., Li, L., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E. M., Christensen, K., Skytthe, A., Kyvik, K. O., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Silberg, J. L., Maes, H. H., Cutler, T. L., Hopper, J. L., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Ullemar, V., Almqvist, C., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Rasmussen, F., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Harris, J. R., Sung, J., Park, H. A., Lee, J., Lee, S. J., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Llewellyn, C. H., Fisher, A., Rebato, E., Busjahn, A., Tomizawa, R., Inui, F., Watanabe, M., Honda, C., Sakai, N., Hur, Y-M., Sørensen, T. I. A., Boomsma, D. I. & Kaprio, J., Dec 2019, In : Twin research and human genetics : the official journal of the International Society for Twin Studies. 22, 6, p. 800-808 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2017

Using Clinical Characteristics to Identify Which Patients With Major Depressive Disorder Have a Higher Genetic Load for Three Psychiatric Disorders

Verduijn, J., Milaneschi, Y., Peyrot, W. J., Hottenga, J. J., Abdellaoui, A., de Geus, E. J. C., Smit, J. H., Breen, G., Lewis, C. M., Boomsma, D. I., Beekman, A. T. F. & Penninx, B. W. J. H., 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 316-324 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2018

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

LifeLines Cohort Study & CHARGE Inflammation Working Group, 1 Nov 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2016

TS-EUROTRAIN: A European-Wide Investigation and Training Network on the Etiology and Pathophysiology of Gilles de la Tourette Syndrome

Forde, N., Kanaan, A. S., Widomska, J., Padmanabhuni, S. S., Nespoli, E., Alexander, J., Rodriguez Arranz, J. J., Fan, S., Houssari, R., Nawaz, M. S., Rizzo, F., Pagliaroli, L., Rodrigues Zilhao Nogueira, N., Aranyi, T., Barta, C., Boeckers, T. M., Boomsma, D. I., Buisman, W. R., Buitelaar, J. K., Cath, D. C. & 22 others, Dietrich, A., Driessen, N., Drineas, P., Dunlap, M., Gerasch, S., Glennon, J., Hengerer, B., van den Heuvel, O. A., Jespersgaard, C., Möller, H. E., Müller-Vahl, K. R., Openneer, T. J. C., Poelmans, G., Pouwels, P. J. W., Scharf, J. M., Stefansson, H., Tümer, Z., Veltman, D. J., van der Werf, Y. D., Hoekstra, P. J., Ludolph, A. & Paschou, P., 2016, In : Frontiers in Neuroscience. 10, 384.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

Relative Telomere Repeat Mass in Buccal and Leukocyte-Derived DNA

Finnicum, C. T., Dolan, C. V., Willemsen, G., Weber, Z. M., Petersen, J. L., Beck, J. J., Codd, V., Boomsma, D. I., Davies, G. E. & Ehli, E. A., 2017, In : PLoS ONE. 12, 1, p. e0170765 e0170765.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Nolte, I. M., Munoz, M. L., Tragante, V., Amare, A. T., Jansen, R., Vaez, A., von der Heyde, B., Avery, C. L., Bis, J. C., Dierckx, B., van Dongen, J., Gogarten, S. M., Goyette, P., Hernesniemi, J., Huikari, V., Hwang, S-J., Jaju, D., Kerr, K. F., Kluttig, A., Krijthe, B. P. & 144 others, Kumar, J., van der Laan, S. W., Lyytikäinen, L-P., Maihofer, A. X., Minassian, A., van der Most, P. J., Müller-Nurasyid, M., Nivard, M., Salvi, E., Stewart, J. D., Thayer, J. F., Verweij, N., Wong, A., Zabaneh, D., Zafarmand, M. H., Abdellaoui, A., Albarwani, S., Albert, C., Alonso, A., Ashar, F., Auvinen, J., Axelsson, T., Baker, D. G., de Bakker, P. I. W., Barcella, M., Bayoumi, R., Bieringa, R. J., Boomsma, D., Boucher, G., Britton, A. R., Christophersen, I., Dietrich, A., Ehret, G. B., Ellinor, P. T., Eskola, M., Felix, J. F., Floras, J. S., Franco, O. H., Friberg, P., Gademan, M. G. J., Geyer, M. A., Giedraitis, V., Hartman, C. A., Hemerich, D., Hofman, A., Hottenga, J-J., Huikuri, H., Hutri-Kähönen, N., Jouven, X., Junttila, J., Juonala, M., Kiviniemi, A. M., Kors, J. A., Kumari, M., Kuznetsova, T., Laurie, C. C., Lefrandt, J. D., Li, Y., Li, Y., Liao, D., Limacher, M. C., Lin, H. J., Lindgren, C. M., Lubitz, S. A., Mahajan, A., McKnight, B., Zu Schwabedissen, H. M., Milaneschi, Y., Mononen, N., Morris, A. P., Nalls, M. A., Navis, G., Neijts, M., Nikus, K., North, K. E., O'Connor, D. T., Ormel, J., Perz, S., Peters, A., Psaty, B. M., Raitakari, O. T., Risbrough, V. B., Sinner, M. F., Siscovick, D., Smit, J. H., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Staessen, J. A., Stein, P. K., Stilp, A. M., Stolarz-Skrzypek, K., Strauch, K., Sundström, J., Swenne, C. A., Syvänen, A-C., Tardif, J-C., Taylor, K. D., Teumer, A., Thornton, T. A., Tinker, L. E., Uitterlinden, A. G., van Setten, J., Voss, A., Waldenberger, M., Wilhelmsen, K. C., Willemsen, G., Wong, Q., Zhang, Z-M., Zonderman, A. B., Cusi, D., Evans, M. K., Greiser, H. K., van der Harst, P., Hassan, M., Ingelsson, E., Järvelin, M-R., Kääb, S., Kähönen, M., Kivimaki, M., Kooperberg, C., Kuh, D., Lehtimäki, T., Lind, L., Nievergelt, C. M., O'Donnell, C. J., Oldehinkel, A. J., Penninx, B., Reiner, A. P., Riese, H., Van Roon, A. M., Rioux, J. D., Rotter, J. I., Sofer, T., Stricker, B. H., Tiemeier, H., Vrijkotte, T. G. M., Asselbergs, F. W., Brundel, B. J. J. M., Heckbert, S. R., Whitsel, E. A., den Hoed, M., Snieder, H. & de Geus, E. J. C., 14 Jun 2017, In : Nature Communications. 8, p. 15805 15805.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2016

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

Hehir-Kwa, J. Y., Marschall, T., Kloosterman, W. P., Francioli, L. C., Baaijens, J. A., Dijkstra, L. J., Abdellaoui, A., Koval, V., Thung, D. T., Wardenaar, R., Renkens, I., Coe, B. P., Deelen, P., de Ligt, J., Lameijer, E. W., Dijk, F., Hormozdiari, F., Uitterlinden, A. G., van Duijn, C. M., Eichler, E. E. & 9 others, Bakker, P. I. W., Swertz, M. A., Wijmenga, C., van Ommen, G. J. B., Slagboom, P. E., Boomsma, D. I., Schönhuth, A., Ye, K. & Guryev, V., 2016, In : Nature Communications. 7, 12989.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

Pappa, I., St Pourcain, B., Benke, K. S., Cavadino, A., Hakulinen, C., Nivard, M. G., Nolte, I. M., Tiesler, C. M. T., Bakermans-Kranenburg, M. J., Davies, G. E., Evans, D. M., Geoffroy, M. C., Grallert, H., Blokhuis, M. M., Hudziak, J. J., Kemp, J. P., Keltikangas-Järvinen, L., McMahon, G., Mileva-Seitz, V. R., Motazedi, E. & 23 others, Power, C., Raitakari, O. T., Ring, S. M., Rivadeneira, F., Rodriguez, A., Scheet, P., Seppälä, I., Snieder, H., Standl, M., Thiering, E., Timpson, N. J., Veenstra, R., Velders, F. P., Whitehouse, A. J. O., Davey Smith, G., Heinrich, J., Hypponen, E., Lehtimäki, T., Middeldorp, C. M., Oldehinkel, A. J., Pennell, C. E., Boomsma, D. I. & Tiemeier, H., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 5, p. 562-572

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Chorionicity and Heritability Estimates from Twin Studies: The Prenatal Environment of Twins and Their Resemblance Across a Large Number of Traits

van Beijsterveldt, C. E. M., Overbeek, L. I. H., Rozendaal, L., McMaster, M. T., Glasner, T., Bartels, M., Vink, J. M., Martin, N. G., Dolan, C. V. & Boomsma, D. I., 2016, In : Behavior Genetics. 46, 3, p. 304-314

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide analysis identifies 12 loci influencing human reproductive behavior.

Barban, N., Jansen, R., de Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Mbarek, H., Boomsma, D. I., de Geus, E. J. C., Penninx, B. W. J. H., Willemsen, G., Zondervan, K. T., Stefansson, K., Krueger, R. F., Lee, J. J., Benjamin, D. J. & 5 others, Cesarini, D., Koellinger, P. D., den Hoed, M. A. H., Snieder, H. & Mills, M. C., 2016, In : Nature Genetics. 48, 12, p. 1462-1472

Research output: Contribution to JournalArticleAcademicpeer-review

2019

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

van Dongen, J., Boomsma, D. I. & BIOS Consortium, 15 Oct 2019, In : Biological Psychiatry. 86, 8, p. 599-607 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017
2018

Genetic and environmental factors affecting birth size variation: A pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts

Yokoyama, Y., Jelenkovic, A., Hur, Y. M., Sund, R., Fagnani, C., Stazi, M. A., Brescianini, S., Ji, F., Ning, F., Pang, Z., Knafo-Noam, A., Mankuta, D., Abramson, L., Rebato, E., Hopper, J. L., Cutler, T. L., Saudino, K. J., Nelson, T. L., Whitfield, K. E., Corley, R. P. & 40 others, Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Llewellyn, C. H., Fisher, A., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Krueger, R. F., McGue, M., Pahlen, S., Bartels, M., Van Beijsterveldt, C. E. M., Willemsen, G., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Rasmussen, F., Tynelius, P., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Rose, R. J., Pietiläinen, K. H., Sørensen, T. I. A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 1 Aug 2018, In : International Journal of Epidemiology. 47, 4, p. 1195-1206 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2019

Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness

23Andme Research Team, 15 Nov 2019, In : Human Molecular Genetics. 28, 22, p. 3853-3865 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Open Access

A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics

Milaneschi, Y., Peyrot, W. J., Nivard, M. G., Mbarek, H., Boomsma, D. I. & W J H Penninx, B., 5 Sep 2019, In : Translational Psychiatry. 9, 1, p. 219 219.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee, P. H., Anttila, V., Won, H., Feng, Y., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., Derks, E. M., op Landt Slof, M. C. T., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., W J H Penninx, B., Cath, D. C. & 11 others, Denys, D., Santangelo, S., Scharf, J. M., Stein, M. B., Thornton, L. M., Walters, J. T. R., Wray, N. R., Geschwind, D. H., Neale, B. M., Kendler, K. S. & Smoller, J. W., 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11 26 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2017

A Genetic Epidemiological Mega Analysis of Smoking Initiation in Adolescents

Maes, H. H., Prom-Wormley, E., Eaves, L. J., Rhee, S. H., Hewitt, J. K., Young, S., Corley, R., McGue, M., Iacono, W. G., Legrand, L., Samek, D. R., Murrelle, E. L., Silberg, J. L., Miles, D. R., Schieken, R. M., Beunen, G. P., Thomis, M., Rose, R. J., Dick, D. M., Boomsma, D. I. & 6 others, Bartels, M., Vink, J. M., Lichtenstein, P., White, V., Kaprio, J. & Neale, M. C., 1 Apr 2017, In : Nicotine and Tobacco Research. 19, 4, p. 401-409 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2018

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

de Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., Noto, C., Curtis, C., Newhouse, S. J., Patel, H., Hall, L. S., O`Reilly, P. F., Belangero, S. I., Bressan, R. A., Breen, G. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 8 Oct 2018, In : Communications biology. 1, p. 1-10 10 p., 163.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

Using a multivariate model to assess the interactive effects of demographics and lifestyle on the hematological profile

McArtor, D. B., Lin, B. D., Hottenga, J-J., Boomsma, D. I., Willemsen, G. & Lubke, G. H., 1 Jun 2017, In : Biomarkers in medicine. 11, 6, p. 427-438 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2018

Polygenic risk for alcohol consumption and its association with alcohol-related phenotypes: Do stress and life satisfaction moderate these relationships?

Mies, G. W., Verweij, K. J. H., Treur, J. L., Ligthart, L., Fedko, I. O., Hottenga, J. J., Willemsen, G., Bartels, M., Boomsma, D. I. & Vink, J. M., 1 Jan 2018, In : Drug and Alcohol Dependence. 183, p. 7-12 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

Luijk, R., Wu, H., Ward-Caviness, C. K., Hannon, E., Carnero-Montoro, E., Min, J. L., Mandaviya, P., Müller-Nurasyid, M., Mei, H., van der Maarel, S. M., Beekman, M., der Breggen, R. V., Deelen, J., Lakenberg, N., Moed, M., Suchiman, H. E. D., Arindrarto, W., van’t Hof, P., Jan Bonder, M., Deelen, P. & 32 others, Tigchelaar, E. F., Zhernakova, A., Zhernakova, D. V., van Dongen, J., Hottenga, J. J., Pool, R., Isaacs, A., Hofman, B. A., Jhamai, M., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., van den Berg, L. H., van Galen, M., Vermaat, M., van Rooij, J., Uitterlinden, A. G., Verbiest, M., Verkerk, M., Kielbasa, P. S. M., Bot, J., Nooren, I., van Dijk, F., Swertz, M. A., van Heemst, D., Relton, C., Mill, J., Waldenberger, M., Bell, J. T., Jansen, R., Boomsma, D. I. & BIOS Consortium, 14 Sep 2018, In : Nature Communications. 9, 1, p. 1-9 9 p., 3738.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies

Haller, T., Leitsalu, L., Fischer, K., Nuotio, M-L., Esko, T., Boomsma, D. I., Kyvik, K. O., Spector, T. D., Perola, M. & Metspalu, A., 20 Jan 2017, In : PLoS ONE. 12, 1, p. e0170325 e0170325.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2018

Metataxonomic Analysis of Individuals at BMI Extremes and Monozygotic Twins Discordant for BMI

Finnicum, C. T., Doornweerd, S., Dolan, C. V., Luningham, J. M., Beck, J. J., Willemsen, G., Ehli, E. A., Boomsma, D. I., Ijzerman, R. G., Davies, G. E. & De Geus, E. J. C., 1 Jun 2018, In : Twin Research and Human Genetics. 21, 3, p. 203-213 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2016

Causes of variation in the neutrophil-lymphocyte and platelet-lymphocyte ratios: a twin-family study

Lin, B., Hottenga, J. J., Abdellaoui, A., Dolan, C. V., de Geus, E. J. C., Kluft, C., Boomsma, D. I. & Willemsen, G., 2016, In : Biomarkers in medicine. 10, 10, p. 1061-1072

Research output: Contribution to JournalArticleAcademicpeer-review

2020

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

BBMRI Metabolomics Consortium, 7 Jan 2020, In : Nature Communications. 11, 1, p. 39 39.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Nivard, M., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C. & W J H Penninx, B., 8 May 2020, In : Nature Communications. 11, 1, p. 2301

Research output: Contribution to JournalArticleAcademicpeer-review

2018

IC-P-066: WHITE MATTER MICROSTRUCTURE AND AMYLOID AGGREGATION IN COGNITIVELY HEALTHY, ELDERLY IDENTICAL TWINS

den Braber, A., Stickney, K., van't Ent, D., ten Kate, M., Konijnenberg, E., Tomassen, J., Barkhof, F., van Berckel, B. N. M., Boomsma, D. I., de Geus, E., Scheltens, P. & Visser, P. J., Jul 2018, In : Alzheimers & Dementia. 14, 7S_Part_1, p. P59-P60

Research output: Contribution to JournalArticleAcademic

2016

Meta-analysis of genome-wide association studies of anxiety disorders

Otowa, T., Hek, K., Byrne, E. M., Mirza, S. S., Nivard, M. G., Bigdeli, T. B., Aggen, S. H., Adkins, D. E., Wolen, A., Fanous, A., Keller, M. C., Castelao, E., Kutalik, Z., van der Auwera, S. V., Homuth, G., Nauck, M., Teumer, A., Milaneschi, Y., Hottenga, J. J., Direk, N. & 26 others, Hofman, A., Uitterlinden, A. G., Mulder, C. L., Henders, A. K., Medland, S. E., Gordon, S., Heath, A. C., Madden, P. A. F., Pergadia, M. L., van der Most, P. J., Nolte, I. M., van Oort, F. V. A., Hartman, C. A., Oldehinkel, A. J., Preisig, M., Grabe, H. J., Middeldorp, C. M., Penninx, B. W. J. H., Boomsma, D. I., Martin, N. G., Montgomery, G. W., Maher, B. S., van den Oord, E. J., Wray, N. R., Tiemeier, H. & Hettema, J. M., 2016, In : Molecular Psychiatry. 21, 10, p. 1391-1399

Research output: Contribution to JournalArticleAcademicpeer-review

2018

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium (vol 84, pg 138, 2018)

Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. . V., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Baune, B. T., Breen, G. & 8 others, Levinson, D. F., Lewis, C. M., Martin, N. G., Nelson, E. N., Boomsma, D. . I., Grabe, H. J., Wray, N. R. & Penninx, B. W. J. H., 1 Dec 2018, In : Biological Psychiatry. 84, 11, p. 857-857

Research output: Contribution to JournalArticleAcademicpeer-review

2019

Multivariate genome-wide analyses of the well-being spectrum

BIOS Consortium, Mar 2019, In : Nature Genetics. 51, 3, p. 445-451 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2017

Association between birthweight and later body mass index: an individual-based pooled analysis of 27 twin cohorts participating in the CODATwins project

Jelenkovic, A., Yokoyama, Y., Sund, R., Pietiläinen, K. H., Hur, Y-M., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Ooki, S., Saudino, K. J., Stazi, M. A., Fagnani, C., D'Ippolito, C., Nelson, T. L., Whitfield, K. E., Knafo-Noam, A., Mankuta, D., Abramson, L., Heikkilä, K., Cutler, T. L. & 46 others, Hopper, J. L., Wardle, J., Llewellyn, C. H., Fisher, A., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Burt, S. A., Klump, K. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Dubois, L., Boivin, M., Brendgen, M. R., Dionne, G., Vitaro, F., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Rasmussen, F., Tynelius, P., Bayasgalan, G., Narandalai, D., Haworth, C. M., Plomin, R., Ji, F., Ning, F., Pang, Z., Rebato, E., Krueger, R. F., McGue, M., Pahlen, S., Boomsma, D. I., Sørensen, T. I., Kaprio, J. & Silventoinen, K., 1 Oct 2017, In : International Journal of Epidemiology. 46, 5, p. 1488-1498 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

A framework for the detection of de novo mutations in family-based sequencing data

Francioli, L. C., Cretu-Stancu, M., Garimella, K. V., Fromer, M., Kloosterman, W. P., Boomsma, D. I., Abdellaoui, A., Hottenga, J. J., Willemsen, G., Samocha, K. E., Neale, B. M., Daly, M. J., Banks, E., DePristo, M. A. & Bakker, P. I. W., Jan 2017, In : European Journal of Human Genetics. 25, 2, p. 227-233 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2016

Multivariate and repeated measure GWAS of aggression phenotypes

Nivard, M. G., Middeldorp, C., Hottenga, J. J., Fedko, I., Ehli, E. A., Davies, G., van Beijsterveldt, C., Bartels, M. & Boomsma, D., Nov 2016, In : Behavior Genetics. 46, 6, p. 798-799

Research output: Contribution to JournalMeeting AbstractOther research output

2017

Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype

Hillger, J. M., le Roy, B., Wang, Z., Mulder-Krieger, T., Boomsma, D. I., Slagboom, P. E., Danen, E. H. J., IJzerman, A. P. & Heitman, L. H., 15 Apr 2017, In : Biochemical Pharmacology. 130, p. 60-70 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2016

The use of vector bootstrapping to improve variable selection precision in Lasso models

Laurin, C., Boomsma, D. I. & Lubke, G. H., 1 Aug 2016, In : Statistical Applications in Genetics and Molecular Biology. 15, 4, p. 305-320 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review