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  • Hans Victor Westerhoff
2016

Synthetic biology and regulatory networks: where metabolic systems biology meets control engineering.

He, F., Murabito, E. & Westerhoff, H. V., 2016, In : Journal of the Royal Society Interface. 117, pii:20151046.

Research output: Contribution to JournalArticle

Open Access

Molecular assessment of bacterial vaginosis by Lactobacillus abundance and species diversity.

Dols, J. A. M., Molenaar, D., van der Helm, J. J., Caspers, M. P., de Kat Angelino-Bart, A., Schuren, F. H., Speksnijder, A. G., Westerhoff, H. V., Richardus, J. H., Boon, M. E., Reid, G., de Vries, H. J. & Kort, R., 2016, In : BMC Infectious Diseases. 16, 180.

Research output: Contribution to JournalArticle

Open Access
2017

Targeting pathogen metabolism without collateral damage to the host.

Haanstra, J. R., Gerding, A., Dolga, A. M., Sorgdrager, F. J., Buist-Homan, M., du Toit, F., Faber, K. N., Holzhutter, H. G., Szoor, B., Matthews, K. R., Snoep, J. L., Westerhoff, H. V. & Bakker, B. M., 2017, In : Scientific Reports. 7, 40406.

Research output: Contribution to JournalArticle

Open Access
2018

Metabolic flexibility of a prospective bioremediator: Desulfitobacterium hafniense Y51 challenged in chemostats

Marozava, S., Vargas-López, R., Tian, Y., Merl-Pham, J., Braster, M., Meckenstock, R. U., Smidt, H., Röling, W. F. M. & Westerhoff, H. V., Jul 2018, In : Environmental Microbiology. 20, 7, p. 2652-2669 18 p.

Research output: Contribution to JournalArticle

2020

Trumping the Trumps: Addressing complexities through BioLogical rationality

Westerhoff, H. V., 17 Jan 2020, Amsterdam: Vrije Universiteit Amsterdam. 37 p.

Research output: Book / ReportValedictory speechProfessional

Open Access
File
2019

Neural plasticity and adult neurogenesis: the deep biology perspective

Colangelo, A., Cirillo, G., Alberghina, L., Papa, M. & Westerhoff, H., 1 Feb 2019, In : Neural Regeneration Research. 14, 2, p. 201-205 5 p.

Research output: Contribution to JournalReview article

Open Access

Ample arsenite bio-oxidation activity in Bangladesh drinking water wells: A bonanza for bioremediation?

Hassan, Z., Sultana, M., Khan, S. I., Braster, M., Röling, W. F. M. & Westerhoff, H. V., Aug 2019, In : Microorganisms. 7, 8, p. 1-22 22 p., 246.

Research output: Contribution to JournalArticle

Open Access
2017

Identification of Three Early Phases of Cell-Fate Determination during Osteogenic and Adipogenic Differentiation by Transcription Factor Dynamics

van de Peppel, J., Strini, T., Tilburg, J., Westerhoff, H., van Wijnen, A. J. & van Leeuwen, J. P., 11 Apr 2017, In : Stem cell reports. 8, 4, p. 947-960 14 p.

Research output: Contribution to JournalArticle

Open Access
2019
Open Access

Integration of single-cell RNA-seq data into population models to characterize cancer metabolism

Damiani, C., Maspero, D., Di Filippo, M., Colombo, R., Pescini, D., Graudenzi, A., Westerhoff, H. V., Alberghina, L., Vanoni, M. & Mauri, G., 28 Feb 2019, In : PLoS Computational Biology. 15, 2, p. 1-25 25 p., e1006733.

Research output: Contribution to JournalArticle

Open Access
2016

MUFINS: multi-formalism interaction network simulator

Wu, H., von Kamp, A., Leoncikas, V., Mori, W., Sahin, N., Gevorgyan, A., Linley, C., Grabowski, M., Mannan, A. A., Stoy, N., Stewart, G. R., Ward, L. T., Lewis, D. J. M., Sroka, J., Matsuno, H., Klamt, S., Westerhoff, H. V., McFadden, J., Plant, N. J. & Kierzek, A. M., 2016, In : NPJ systems biology and applications. 2, 16032.

Research output: Contribution to JournalArticle

Open Access
2017

A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect

Damiani, C., Colombo, R., Gaglio, D., Mastroianni, F., Pescini, D., Westerhoff, H. V., Mauri, G., Vanoni, M. & Alberghina, L., 1 Sep 2017, In : PLoS Computational Biology. 13, 9, e1005758.

Research output: Contribution to JournalArticle

Open Access
2018

NET works after all? Engineering robustness through diversity

Mondeel, T. D. G. A., Astrologo, S., Zhang, Y. & Westerhoff, H. V., 2018, In : IFAC-PapersOnLine. 51, 19, p. 128-137 10 p.

Research output: Contribution to JournalArticle

Predictable irreversible switching between acute and chronic inflammation

Abudukelimu, A., Barberis, M., Redegeld, F. A., Sahin, N. & Westerhoff, H. V., 7 Aug 2018, In : Frontiers in Immunology. 9, AUGUST, p. 1-16 16 p., 1596.

Research output: Contribution to JournalArticle

Open Access
2017

The peculiar glycolytic pathway in hyperthermophylic archaea: Understanding its whims by experimentation in silico

Zhang, Y., Kouril, T., Snoep, J. L., Siebers, B., Barberis, M. & Westerhoff, H. V., 20 Apr 2017, In : International Journal of Molecular Sciences. 18, 4, 876.

Research output: Contribution to JournalArticle

Open Access

Learning to read and write in evolution: From static pseudoenzymes and pseudosignalers to dynamic gear shifters

Abudukelimu, A., Mondeel, T. D. G. A., Barberis, M. & Westerhoff, H. V., 15 Jun 2017, In : Biochemical Society Transactions. 45, 3, p. 635-652 18 p.

Research output: Contribution to JournalReview article

2020

Complex Stability and an Irrevertible Transition Reverted by Peptide and Fibroblasts in a Dynamic Model of Innate Immunity

Abudukelimu, A., Barberis, M., Redegeld, F., Sahin, N., Sharma, R. P. & Westerhoff, H. V., 14 Feb 2020, In : Frontiers in Immunology. 10, p. 1-20 20 p., 3091.

Research output: Contribution to JournalArticle

Open Access

Development and evaluation of a harmonized whole body physiologically based pharmacokinetic (PBPK) model for flutamide in rats and its extrapolation to humans

Sharma, R. P., Kumar, V., Schuhmacher, M., Kolodkin, A. & Westerhoff, H. V., 1 Mar 2020, In : Environmental Research. 182, p. 1-14 14 p., 108948.

Research output: Contribution to JournalArticle

2018

STRENDA DB: enabling the validation and sharing of enzyme kinetics data

Swainston, N., Baici, A., Bakker, B. M., Cornish-Bowden, A., Fitzpatrick, P. F., Halling, P., Leyh, T. S., O'Donovan, C., Raushel, F. M., Reschel, U., Rohwer, J. M., Schnell, S., Schomburg, D., Tipton, K. F., Tsai, M. D., Westerhoff, H. V., Wittig, U., Wohlgemuth, R. & Kettner, C., 1 Jun 2018, In : FEBS Journal. 285, 12, p. 2193-2204 12 p.

Research output: Contribution to JournalComment / Letter to the editor

Rational cell culture optimization enhances experimental reproducibility in cancer cells

Wright Muelas, M., Ortega, F., Breitling, R., Bendtsen, C. & Westerhoff, H. V., 14 Feb 2018, In : Scientific Reports. 8, 1, p. 1-16 16 p., 3029.

Research output: Contribution to JournalArticle

Open Access