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  • D. Posthuma
2016

Multivariate Gene-Based Association Test on Family Data in MGAS.

Vroom, C., Posthuma, D., Li, M. X., Dolan, C. V. & van der Sluis, S., 2016, In : Behavior Genetics. 46, p. 718-725 5.

Research output: Contribution to JournalArticle

Open Access
2017

Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images

Guo, S., Lai, C., Wu, C., Cen, G., Alzheimer's Disease Neuroimaging Initiative & Posthuma, D., 2017, In : Frontiers in Aging Neuroscience. 9, MAY, p. 146 146.

Research output: Contribution to JournalArticle

Open Access
2016

Involvement of astrocyte and oligodendrocyte gene sets in migraine.

Eising, E., Leeuw, C., Min, J. L., Anttila, V., Verheijen, M. H. G., Terwindt, G. M., Dichgans, M., Freilinger, T., Kubisch, C., Ferrari, M. D., Smit, A. B., de Vries, B., Palotie, A., van den Maagdenberg, A. M. J. M. & Posthuma, D., 2016, (Accepted/In press) In : Cephalalgia. 36, p. 640-647 7.

Research output: Contribution to JournalArticle

2017

Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

Sniekers, S., Stringer, S., Watanabe, K., Jansen, P. R., Coleman, J. R. I., Krapohl, E., Taskesen, E., Hammerschlag, A. R., Okbay, A., Zabaneh, D., Amin, N., Breen, G., Cesarini, D., Chabris, C. F., Iacono, W. G., Ikram, M. A., Johannesson, M., Koellinger, P., Lee, J. J., Magnusson, P. K. E. & 10 others, McGue, M., Miller, M. B., Ollier, W. E. R., Payton, A., Pendleton, N., Plomin, R., Rietveld, C. A., Tiemeier, H., van Duijn, C. M. & Posthuma, D., Jul 2017, In : Nature Genetics. 49, 7, p. 1107-1112 6 p.

Research output: Contribution to JournalArticle

Open Access
2019

Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Agrawal, A., Børglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R., Sullivan, P. F., Posthuma, D. & 1 others, Polderman, T. J. C., May 2019, In : Psychological Medicine. 49, 7, p. 1166-1173 8 p.

Research output: Contribution to JournalArticle

Open Access

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

The 23andMe Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 394-403 10 p.

Research output: Contribution to JournalArticle

Open Access
File
2018

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

de Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., Noto, C., Curtis, C., Newhouse, S. J., Patel, H., Hall, L. S., O`Reilly, P. F., Belangero, S. I., Bressan, R. A., Breen, G. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 8 Oct 2018, In : Communications biology. 1, p. 1-10 10 p., 163.

Research output: Contribution to JournalArticle

Open Access
2019

Common Polygenic Variations for Psychiatric Disorders and Cognition in Relation to Brain Morphology in the General Pediatric Population

Alemany, S., Jansen, P. R., Muetzel, R. L., Marques, N., El Marroun, H., Jaddoe, V. W. V., Polderman, T. J. C., Tiemeier, H., Posthuma, D. & White, T., 9 Jan 2019, (Accepted/In press) In : Journal of the American Academy of Child and Adolescent Psychiatry. 58, 6, p. 1-8 8 p.

Research output: Contribution to JournalArticle

Open Access
File
2018

Item-level analyses reveal genetic heterogeneity in neuroticism

Nagel, M., Watanabe, K., Stringer, S., Posthuma, D. & Van Der Sluis, S., 2 Mar 2018, In : Nature Communications. 9, 1, p. 1-10 10 p., 905.

Research output: Contribution to JournalArticle

Open Access
2017

Incidental Findings on Brain Imaging in the General Pediatric Population

Jansen, P. R., Dremmen, M., van den Berg, A., Dekkers, I. A., Blanken, L. M. E., Muetzel, R. L., Bolhuis, K., Mulder, R. M., Kocevska, D., Jansen, T. A., de Wit, M-C. Y., Neuteboom, R. F., Polderman, T. J. C., Posthuma, D., Jaddoe, V. W. V., Verhulst, F. C., Tiemeier, H., van der Lugt, A. & White, T. J. H., 19 Oct 2017, In : New England Journal of Medicine. 377, 16, p. 1593-1595 3 p.

Research output: Contribution to JournalArticle

Functional mapping and annotation of genetic associations with FUMA

Watanabe, K., Taskesen, E., van Bochoven, A. & Posthuma, D., 28 Nov 2017, In : Nature Communications. 8, 1, p. 1826 1826.

Research output: Contribution to JournalArticle

Open Access
2018

Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population

Jansen, P. R., Polderman, T. J. C., Bolhuis, K., van der Ende, J., Jaddoe, V. W. V., Verhulst, F. C., White, T., Posthuma, D. & Tiemeier, H., 1 Jan 2018, In : Journal of Child Psychology and Psychiatry. 59, 1, p. 39-47 9 p.

Research output: Contribution to JournalArticle

Open Access
File
2017

Gene-based association studies report genetic links for clinical subtypes of frontotemporal dementia

Mishra, A., Ferrari, R., Heutink, P., Hardy, J., Pijnenburg, Y., Posthuma, D. & International FTD-Genomics Consortium, 1 May 2017, In : Brain. 140, 5, p. 1437-1446 10 p.

Research output: Contribution to JournalArticle

2016

The statistical properties of gene-set analysis.

de Leeuw, C. A., Neale, B. M., Heskes, T. & Posthuma, D., 2016, In : Nature Reviews Genetics. 17, p. 353-364 6.

Research output: Contribution to JournalArticle

2019

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, 1 May 2019, In : Nature Genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to JournalArticle

Open Access
File
2018

The Biological Contributions to Gender Identity and Gender Diversity: Bringing Data to the Table

on behalf of the International Gender Diversity Genomics Consortium, Mar 2018, In : Behavior Genetics. 48, 2, p. 95-108 14 p.

Research output: Contribution to JournalReview article

Open Access
File
2017

Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS

Taskesen, E., Mishra, A., van der Sluis, S., Ferrari, R., Veldink, J. H., van Es, M. A., Smit, A. B., Posthuma, D. & Pijnenburg, Y., 21 Aug 2017, In : Scientific Reports. 7, 1, p. 8899 8899.

Research output: Contribution to JournalArticle

Open Access

Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome

Huang, A. Y., Yu, D., Davis, L. K., Sul, J. H., Tsetsos, F., Ramensky, V., Zelaya, I., Ramos, E. M., Osiecki, L., Chen, J. A., McGrath, L. M., Illmann, C., Sandor, P., Barr, C. L., Grados, M., Singer, H. S., Nöthen, M. M., Hebebrand, J., King, R. A., Dion, Y. & 31 others, Rouleau, G., Budman, C. L., Depienne, C., Worbe, Y., Hartmann, A., Müller-Vahl, K. R., Stuhrmann, M., Aschauer, H., Stamenkovic, M., Schloegelhofer, M., Konstantinidis, A., Lyon, G. J., McMahon, W. M., Barta, C., Tarnok, Z., Nagy, P., Batterson, J. R., Rizzo, R., Cath, D. C., Wolanczyk, T., Berlin, C., Malaty, I. A., Okun, M. S., Woods, D. W., Rees, E., Pato, C. N., Pato, M. T., Knowles, J. A., Posthuma, D., Pauls, D. L. & Tourette Syndrome Association International Consortium for Genetics (TSAICG), 21 Jun 2017, In : Neuron. 94, 6, p. 1101-1111.e7

Research output: Contribution to JournalArticle

Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior

Tielbeek, J. J., Johansson, A., Polderman, T. J. C., Rautiainen, M-R., Jansen, P., Taylor, M., Tong, X., Lu, Q., Burt, A. S., Tiemeier, H., Viding, E., Plomin, R., Martin, N. G., Heath, A. C., Madden, P. A. F., Montgomery, G., Beaver, K. M., Waldman, I., Gelernter, J., Kranzler, H. R. & 20 others, Farrer, L. A., Perry, J. R. B., Munafò, M., LoParo, D., Paunio, T., Tiihonen, J., Mous, S. E., Pappa, I., de Leeuw, C., Watanabe, K., Hammerschlag, A. R., Salvatore, J. E., Aliev, F., Bigdeli, T. B., Dick, D., Faraone, S. V., Popma, A., Medland, S. E., Posthuma, D. & Broad Antisocial Behavior Consortium collaborators, 1 Dec 2017, In : JAMA Psychiatry. 74, 12, p. 1242-1250 9 p.

Research output: Contribution to JournalArticle

2019

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee, P. H., Anttila, V., Won, H., Feng, Y., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., Derks, E. M., op Landt Slof, M. C. T., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., W J H Penninx, B., Cath, D. C. & 11 others, Denys, D., Santangelo, S., Scharf, J. M., Stein, M. B., Thornton, L. M., Walters, J. T. R., Wray, N. R., Geschwind, D. H., Neale, B. M., Kendler, K. S. & Smoller, J. W., 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11 26 p.

Research output: Contribution to JournalArticle

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Sullivan, P., 11 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to JournalArticle

2017

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, Locke, A. E., Masca, N. G. D., Ng, M. C. Y., Mudgal, P., Rivas, M. A., Vedantam, S., Mahajan, A., Guo, X., Abecasis, G., Aben, K. K., Adair, L. S., Alam, D. S., Albrecht, E., Allin, K. H., Allison, M., Amouyel, P., Appel, E. V., Arveiler, D., Asselbergs, F. W., Auer, P. L., Balkau, B., Banas, B., Bang, L. E., Benn, M., Bergmann, S., Bielak, L. F., Blüher, M., Boeing, H., Boerwinkle, E., Posthuma, D. & EPIC-InterAct Consortium, 9 Feb 2017, In : Nature. 542, 7640, p. 186-190 5 p.

Research output: Contribution to JournalArticle

Open Access
2016

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T., Ran, C., Gordon, S. G., Stam, A. H. & 88 others, Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Gudlaug Hrafnsdottir, M., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M. A., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Kurki, M. I., Kals, M., Mägi, R., Pärn, K., Hämaläinen, E., Huang, H., Byrnes, A. E., Franke, L., Huang, J., Stergiakouli, E., Lee, P. H., Sandor, C., Webber, C., Cader, Z., Müller-Myhsok, B., Schreiber, S., Meitinger, T., Eriksson, J. G., Salomaa, V., Heikkilä, K., Loehrer, A. G., Uitterlinden, A. G., Hofman, A., van Duijn, C. M., Cherkas, L., Pedersen, L., Stubhaug, A., Nielsen, C. S., Männikkö, M., Mihailov, E., Milani, L., Göbel, H., Esserlind, A. L., Francke Christensen, A., Folkmann Hansen, T., Werge, T., Kaprio, J., Aromaa, A., Raitakari, O., Ikram, M. A., Spector, T. D., Järvelin, M. R., Metspalu, A., Kubisch, C., Strachan, D. P., Ferrari, M. D., Belin, A. C., Dichgans, M., Wessman, M., van den Maagdenberg, A. M. J. M., Zwart, J. A., Boomsma, D. I., Davey Smith, G., Stefansson, K., Eriksson, N., Daly, M. J., Neale, B. M., Olesen, J., Chasman, D. I., Nyholt, DR., Palotie, A. & Posthuma, D., 2016, In : Nature Genetics. 48, 8, p. 856-866

Research output: Contribution to JournalArticle

2019

Polygenic Scores for Neuropsychiatric Traits and White Matter Microstructure in the Pediatric Population

Jansen, P. R., Muetzel, R. L., Polderman, T. J. C., Jaddoe, V. W., Verhulst, F. C., van der Lugt, A., Tiemeier, H., Posthuma, D. & White, T., Mar 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 3, p. 243-250 8 p.

Research output: Contribution to JournalArticle

Open Access
File
2020

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Beekman, A. F. T., Jansen, R., Milaneschi, Y., Peyrot, W. J., Smit, J. H., W J H Penninx, B. & Posthuma, D., 16 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to JournalArticle

2019
Open Access
2018

Exploring the role of low-frequency and rare exonic variants in alcohol and tobacco use

Marees, A. T., Hammerschlag, A. R., Bastarache, L., de Kluiver, H., Vorspan, F., van den Brink, W., Smit, D. J., Denys, D., Gamazon, E. R., Li-Gao, R., Breetvelt, E. J., de Groot, M. C. H., Galesloot, T. E., Vermeulen, S. H., Poppelaars, J. L., Souverein, P. C., Keeman, R., de Mutsert, R., Noordam, R., Rosendaal, F. R. & 13 others, Stringa, N., Mook-Kanamori, D. O., Vaartjes, I., Kiemeney, L. A., den Heijer, M., van Schoor, N. M., Klungel, O. H., Maitland-Van der Zee, A. H., Schmidt, M. K., Polderman, T. J. C., van der Leij, A. R., Posthuma, D. & Derks, E. M., 1 Jul 2018, In : Drug and Alcohol Dependence. 188, p. 94-101 8 p.

Research output: Contribution to JournalArticle

Open Access
2019

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

CHD Exome+ Consortium & Consortium for Genetics of Smoking Behaviour, 1 Jun 2019, In : Biological Psychiatry. 85, 11, p. 946-955 10 p.

Research output: Contribution to JournalArticle

Open Access
File
2018

Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis

Posthuma, D. & International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS), 1 May 2018, In : Molecular Psychiatry. 23, 5, p. 1181-1188 8 p.

Research output: Contribution to JournalArticle

Open Access
File
2019

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., Hussain, N. K., Imig, C., de Jong, A. P. H., Jung, H., Kohansalnodehi, M., Kramarz, B., Lipstein, N., Lovering, R. C., MacGillavry, H., Mariano, V. & 53 others, Mi, H., Ninov, M., Osumi-Sutherland, D., Pielot, R., Smalla, K. H., Tang, H., Tashman, K., Toonen, R. F. G., Verpelli, C., Reig-Viader, R., Watanabe, K., van Weering, J., Achsel, T., Ashrafi, G., Asi, N., Brown, T. C., De Camilli, P., Feuermann, M., Foulger, R. E., Gaudet, P., Joglekar, A., Kanellopoulos, A., Malenka, R., Nicoll, R. A., Pulido, C., de Juan-Sanz, J., Sheng, M., Südhof, T. C., Tilgner, H. U., Bagni, C., Bayés, À., Biederer, T., Brose, N., Chua, J. J. E., Dieterich, D. C., Gundelfinger, E. D., Hoogenraad, C., Huganir, R. L., Jahn, R., Kaeser, P. S., Kim, E., Kreutz, M. R., McPherson, P. S., Neale, B. M., O'Connor, V., Posthuma, D., Ryan, T. A., Sala, C., Feng, G., Hyman, S. E., Thomas, P. D., Smit, A. B. & Verhage, M., 17 Jul 2019, In : Neuron. 103, 2, p. 217-234.e4 22 p.

Research output: Contribution to JournalArticle

Open Access
File

Translating genome-wide association findings into new therapeutics for psychiatry.

Breen, G., Li, Q., Roth, B. L., O'Donnell, P., Didriksen, M., Dolmetsch, R., O'Reilly, P. F., Gaspar, H. A., Manji, H., Huebel, C., Kelsoe, J. R., Malhotra, D., Bertolino, A., Posthuma, D., Sklar, P., Kapur, S., Sullivan, P. F., Collier, D. A. & Edenberg, H. J., 2016, In : Nature Neuroscience. 19, 11, p. 1392-1396

Research output: Contribution to JournalArticle

Modeling psychiatric disorders: from genomic findings to cellular phenotypes.

Falk, A., Heine, V. M., Harwood, A., Sullivan, P. F., Peitz, M., Brüstle, O., Shen, S., Sun, Y. M. S., Glover, J. C., Posthuma, D. & Djurovic, S., 2016, In : Molecular Psychiatry. 21

Research output: Contribution to JournalArticle

Gene expression in major depressive disorder.

Jansen, R., Penninx, B. W. J. H., Madar, V., Xia, K., Milaneschi, Y., Hottenga, J. J., Hammerschlag, A. R., Beekman, A. T. F., van der Wee, N., Smit, J. H., Brooks, A. I., Tischfield, J., Posthuma, D., Schoevers, R., Grootheest, G., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Wright, F. A., Zou, F. & 2 others, Sun, W. & Sullivan, P. F., 2016, In : Molecular Psychiatry. 21, p. 339 347 p.

Research output: Contribution to JournalArticle

A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts

Middeldorp, C. M., Hammerschlag, A. R., Ouwens, K. G., Blokhuis, M. M., St. Pourcain, B., Greven, C. U., Pappa, I., Tiesler, C. M. T., Ang, W., Nolte, I. M., Vilor-Tejedor, N., Bacelis, J., Ebejer, J. L., Zhao, H., Davies, G. E., Ehli, E. A., Evans, D. M., Fedko, I. O., Guxens, M., Hottenga, J. J. & 31 others, Hudziak, J. J., Jugessur, A., Kemp, J. P., Krapohl, E., Martin, N. G., Murcia, M., Myhre, R., Ormel, J., Ring, S. M., Standl, M., Stergiakouli, E., Stoltenberg, C., Thiering, E., Timpson, N. J., Trzaskowski, M., van der Most, P. J., Wang, C., Nyholt, DR., Medland, S. E., Neale, B. M., Jacobsson, B., Sunyer, J., Hartman, C. A., Whitehouse, A. J. O., Pennell, C. E., Heinrich, J., Plomin, R., Davey Smith, G., Tiemeier, H., Posthuma, D. & Boomsma, D. I., 2016, In : Journal of the American Academy of Child and Adolescent Psychiatry. 55, 10, p. 896-905 10.

Research output: Contribution to JournalArticle

2020

The genetic architecture of the human cerebral cortex

Alzheimer’s Disease Neuroimaging Initiative, 20 Mar 2020, In : Science. 367, 6484, eaay6690.

Research output: Contribution to JournalArticle

2017

Gene-set analysis shows association between FMRP targets and autism spectrum disorder

Jansen, A., Dieleman, G. C., Smit, A. B., Verhage, M., Verhulst, F. C., Polderman, T. J. C. & Posthuma, D., Jun 2017, In : European Journal of Human Genetics. 25, 7, p. 863-868 6 p.

Research output: Contribution to JournalArticle

2018

Association of genetic risk for schizophrenia and bipolar disorder with infant neuromotor development

Serdarevic, F., Jansen, P. R., Ghassabian, A., White, T., Jaddoe, V. W. V., Posthuma, D. & Tiemeier, H., Jan 2018, In : JAMA Psychiatry. 75, 1, p. 96-98 3 p.

Research output: Contribution to JournalLetter

Open Access
File

Genetic correlation of antisocial behaviour with alcohol, nicotine, and cannabis use

Tielbeek, J. J., Vink, J. M., Polderman, T. J. C., Popma, A., Posthuma, D. & Verweij, K. J. H., 1 Jun 2018, In : Drug and Alcohol Dependence. 187, p. 296-299 4 p.

Research output: Contribution to JournalArticle

Open Access
2019

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B., Jansen, R. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticle

Open Access
2018

Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure

de Leeuw, C. A., Stringer, S., Dekkers, I. A., Heskes, T. & Posthuma, D., 14 Sep 2018, In : Nature Communications. 9, p. 1-13 13 p., 3768.

Research output: Contribution to JournalArticle

Open Access
2019

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23Andme Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to JournalArticle

Open Access
File
2018

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

23Andme Research Team, 1 Jul 2018, In : Nature Genetics. 50, 7, p. 920-927 8 p.

Research output: Contribution to JournalArticle

Open Access
File
2019

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

iPSYCH-GEMS Schizophrenia Working Group, CommonMind Consortium & The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, 25 Mar 2019, In : Nature Genetics. 51, 4, p. 659–674 16 p.

Research output: Contribution to JournalArticle

Open Access
File

Interrogating the genetic determinants of Tourette's syndrome and other tiC disorders through genome-wide association studies

Tourette Association of America International Consortium for Genetics, Gilles de la Tourette GWAS Replication Initiative, Tourette International Collaborative Genetics Study & Psychiatric Genomics Consortium Tourette Syndrome Working Group, 1 Mar 2019, In : American Journal of Psychiatry. 176, 3, p. 217-227 11 p.

Research output: Contribution to JournalArticle

File

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 11 Jun 2019, In : Nature Communications. 10, 1, p. 1-18 18 p., 2548.

Research output: Contribution to JournalArticle

Open Access

Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls-CORRIGENDUM

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Agrawal, A., Borglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardinãs, A. F., Stahl, E., Walters, J. T. R., Walters, R., Sullivan, P. F., Posthuma, D. & 1 others, Polderman, T. J. C., Jan 2019, In : Psychological Medicine. 49, 2, p. 351-351 1 p.

Research output: Contribution to JournalErratum

Open Access
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The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Posthuma, D., 1 Nov 2019, In : Biological Psychiatry.

Research output: Contribution to JournalArticle

Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease

Broce, I. J., Tan, C. H., Fan, C. C., Jansen, I., Savage, J. E., Witoelar, A., Wen, N., Hess, C. P., Dillon, W. P., Glastonbury, C. M., Glymour, M., Yokoyama, J. S., Elahi, F. M., Rabinovici, G. D., Miller, B. L., Mormino, E. C., Sperling, R. A., Bennett, D. A., McEvoy, L. K., Brewer, J. B. & 14 others, Feldman, H. H., Hyman, B. T., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Schellenberg, G. D., Yaffe, K., Sugrue, L. P., Dale, A. M., Posthuma, D., Andreassen, O. A., Karch, C. M. & Desikan, R. S., 11 Feb 2019, In : Acta Neuropathologica. 137, p. 209-226 18 p.

Research output: Contribution to JournalArticle

2018

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia

23Andme Research Team, Sep 2018, In : Nature Neuroscience. 21, 9, p. 1161-1170 10 p.

Research output: Contribution to JournalArticle

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