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  • C.M. Middeldorp
2011

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

Middeldorp, C. M., de Moor, M. H. M., McGrath, L. M., Gordon, S. D., Blackwood, D. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J. C., Nyholt, DR., Tanaka, T., Esko, T., Madden, P. A. F., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S. & 41 others, Spinhoven, P., Hartman, C. A., Ripke, S., Sullivan, P. F., Realo, A., Allik, J., Heath, A. C., Pergadia, M. L., Agrawal, A., Lin, P., Grucza, R. A., Widen, E., Cousminer, D. L., Eriksson, J. G., Palotie, A., Barnett, J. H., Lee, P. H., Luciano, M., Tenesa, A., Davies, G., Lopez, L. M., Hansell, N. K., Medland, S. E., Ferrucci, L., Schlessinger, D., Montgomery, GW., Wright, M. J., Aulchenko, Y. S., Janssens, A. C. J. W., Oostra, B. A., Metspalu, A., Abecasis, G. R., Deary, I. J., Räikkönen, K., Bierut, L. J., Martin, N. G., Wray, N. R., van Duijn, C. M., Smoller, J. W., Penninx, B. W. J. H. & Boomsma, D. I., 2011, In : Translational Psychiatry. 1, e50.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
2017

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., Kutalik, Z., Lee, S. H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N. R., Arolt, V., Baune, B. T., Boomsma, D. I., Børglum, A. D., Byrne, E. M., Castelao, E., Craddock, N. & 31 others, Craig, I. W., Dannlowski, U., Deary, I. J., Degenhardt, F., Forstner, A. J., Gordon, S. D., Grabe, H. J., Grove, J., Hamilton, S. P., Hayward, C., Heath, A. C., Hocking, L. J., Homuth, G., Hottenga, J. J., Kloiber, S., Krogh, J., Landén, M., Lang, M., Levinson, D. F., Lichtenstein, P., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Middeldorp, C. M., Milaneschi, Y., Penninx, B. W. J. H., Smit, J. H. & CONVERGE Consortium, CARDIoGRAM Consortium, GERAD1 Consortium, 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 325-335 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2011
2013

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Smoller, J. W., Ripke, S., Lee, P. H., Neale, B., Nurnberger, J. I., Santangelo, S., Sullivan, P. F., Perlis, R. H., Purcell, S. M., Fanous, A., Neale, M. C., Rietschel, M., Schulze, T. G., Thapar, A., Anney, R., Buitelaar, J. K., Farone, S. V., Hoogendijk, W. J. G., Levinson, D. F., Lesch, K. P. & 291 others, Riley, B., Schachar, R., Sonuga-Barke, E. J., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Arking, D., Asherson, P., Azevedo, M. H., Backlund, L., Badner, J. A., Banaschewski, T., Barchas, J. D., Barnes, M. R., Bass, N., Bauer, M. C. R., Bellivier, F., Bergen, S. E., Berrettini, W., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Buccola, N. G., Bunner, W. E., Burmeister, M., Buxbaum, J. D., Byerley, W. F., Sian, C., Cantor, R. M., Chakravarti, A., Chambert, K., Chicon, S., Cloniger, C. R., Collier, D. A., Cook, E., Coon, H., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Curtis, D., Czamara, D., Daly, M., Datta, S., Day, R., de Geus, E. J. C., Degenhardt, F., Devlin, B., Srdjan, D., Doyle, A. E., Duan, J., Dudbridge, F., Edenberg, H. J., Elkin, A., Etain, B., Farmer, A. E., Ferreira, M. A. R., Ferrier, I. N., Flickinger, M., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Friedl, M., Frisén, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Gross, M., Grozeva, D., Guan, W., Gurling, H., Gustafsson, O., Hakonarson, H., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hottenga, J. J., Hultman, C. M., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, L., Jones, I., Jung-Ying, T., Kahler, A., Kandaswamy, R., Keller, M. C., Kelsoe, J., Kennedy, J. L., Kenny, E., Kim, Y., Kirov, G. K., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krasucki, R., Kuntsi, J., Phoenix, K., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Lencz, T., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D., Liu, C., Lohoff, F. W., Loo, S. K., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Magnusson, P., Mahon, P. B., Maier, W., Malhotra, A. K., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S., McGhee, K. A., McGough, J. J., McGrath, P. J., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McClean, A. W., McMahon, F. J., McQuillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Middeldorp, C. M., Middleton, L., Vihra, M., Mitchell, P. B., Montgomery, G. W., Moran, J., Morken, G., Morris, D. W., Moskvina, V., Mowry, B. J., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Myers, R. M., Nelson, S. F., Nievergelt, C. M., Nikolovq, I., Nimgaonkar, V. L., Nolen, W. A., Nöthen, M. M., Nwulia, E. A., Nyholt, DR., O'Donovan, M. C., O'Dushlaine, C., Oades, R. D., Olincy, A., Olsen, L., Ophoff, R. A., Osby, U., Óskarsson, H., Owen, M. J., Palotie, A., Pato, M. T., Pato, C. N., Penninx, B. W. J. H., Pergadia, M. L., Petursson, H., Pickard, B. S., Pimm, J., Piven, J., Porgeirsson, P., Posthuma, D., Potash, J. B., Propping, J., Puri, V., Quested, D., Quinn, E. M., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Rice, J., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Schofield, P. R., Schork, N. J., Schumacher, J., Schwarz, M. M., Scolnick, E., Scott, L. J., Shi, J., Shillling, P. D., Shyn, S. I., Sigurdsson, E., Silverman, J. M., Sklar, P., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E., St Clair, D., State, M., Stefansson, K., Stefansson, H., Steffans, M., Steinberg, S., Steinhausen, H. C., Strauss, J., Strohmaier, J., Stroup, T. S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J., Grootheest, G., Vieland, V., Vincent, J. B., Visscher, P. M., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Willemsen, G., Williamson, R., Witt, S. H., Wray, N. R., Wright, A., Xu, W., Young, A. H., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S. & Kendler, K. S., 2013, In : Lancet. 381, 9875, p. 1371-1379

Research output: Contribution to JournalArticleAcademicpeer-review

2019

Genetisch onderzoek: Onderdeel van psychiatrische kliniek

Translated title of the contribution: Genetic diagnostics: Part of the psychiatric clinicMiddeldorp, C. M., 1 Jan 2019, In : Tijdschrift voor Psychiatrie. 61, 6, p. 373-374 2 p.

Research output: Contribution to JournalComment / Letter to the editorAcademic

2011

Birth weight in a large series of triplets

Ponsen-Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M., Vink, J. M., Haak, M. C. & Boomsma, D. I., 2011, In : BMC Pediatrics. 11, 24.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
2017

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D. J., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Lopezz de Alda, M., Alliey-Rodriguez, N. & 31 others, Andreassen, O. A., Babadjanova, G., Bass, N. J., Bauer, M., Baune, B. T., Bellivier, F., Bergen, S. E., Bethell, A., Biernacka, J. M., Blackwood, D. H. R., Boks, M. P., Boomsma, D. I., Børglum, A. D., Borrmann-Hassenbach, M., Brennan, P., Budde, M., Buttenschøn, H. N., Byrne, E. M., Cervantes, P., Clarke, T. K., Craddock, N., Cruceanu, C., Curtis, D., de Geus, E. J. C., Fischer, S. B., Hottenga, J-J., Middeldorp, C. M., Milaneschi, Y., Penninx, B. W. J. H., Willemsen, G. & Bipolar Disorders Working Group of the Psychiatric Genomics Consortium, 20 Jun 2017, In : Translational Psychiatry. 7, 6, p. e1155

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2011

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

Demirkan, A., Penninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlinden, A. G., Hottenga, J. J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. & 1 others, Middeldorp, C. M., 2011, In : Molecular Psychiatry. 16, 7, p. 773-783

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2010

Childhood and Adolescent Anxiety and Depression: Beyond Heritability

Franic, S., Middeldorp, C. M., Dolan, C. V., Ligthart, L. & Boomsma, D. I., 2010, In : Journal of the American Academy of Child and Adolescent Psychiatry. 49, 8, p. 820-829

Research output: Contribution to JournalArticleAcademicpeer-review

2018
Open Access
2010

Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

Middeldorp, C. M., Slof-Op 't Landt, M. C. T., Medland, S. E., van Beijsterveldt, C. E. M., Bartels, M., Willemsen, G., Hottenga, J. J., de Geus, E. J. C., Suchiman, H. E. D., Dolan, C. V., Neale, M. C., Slagboom, P. E. & Boomsma, D. I., 2010, In : Genes, Brain and Behavior. 9, 6, p. 808-816

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

Genetic effects influencing risk for major depressive disorder in China and Europe

Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S. A., Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschøn, H. N., Byrne, E. M., Cichon, S., Clarke, T. K., Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F. & 77 others, Dunn, E. C., Edwards, C. A., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D. S., Grabe, H. J., Hamilton, S. P., Hardiman, O., Hayward, C., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Hottenga, J-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J. A., Lang, M., Li, Q. S., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Martin, N. G., McGrath, P. J., McGuffin, P., McIntosh, A. M., Medland, S. E., Mehta, D., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D. R., Nöthen, M. M., Owen, M. J., Penninx, B. W. J. H., Pergadia, M. L., Perlis, R. H., Peyrot, W. J., Porteous, D. J., Potash, J. B., Rice, J. P., Rietschel, M., Riley, B. P., Rivera, M., Schoevers, R., Schulze, T. G., Shi, J., Shyn, S. I., Smit, J. H., Smoller, J. W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., van der Auwera, S. V., Grootheest, G., van Hemert, A. M., Völzke, H., Webb, B. T., Weissman, M. M., Wellmann, J., Willemsen, G., Witt, S. H., Levinson, D. F., Lewis, C. M., Wray, N. R., Flint, J., Sullivan, P. F. & Kendler, K. S., 28 Mar 2017, In : Translational Psychiatry. 7, 3, p. e1074 e1074.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2011

Life events and borderline personality features: the influence of gene–environment interaction and gene–environment correlation

Distel, M. A., Middeldorp, C. M., Trull, T. J., Derom, C. A., Willemsen, G. & Boomsma, D. I., 2011, In : Psychological Medicine. 41, 4, p. 849-860

Research output: Contribution to JournalArticleAcademicpeer-review

2019

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

EArly Genetics Lifecourse Epidemiology (EAGLE) consortium & Early Growth Genetics (EGG) Consortium, Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2012
2017

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Hinney, A., Kesselmeier, M., Jall, S., Volckmar, A-L., Föcker, M., Antel, J., Heid, I. M., Winkler, T. W., Grant, S. F. A., Guo, Y., Bergen, A. W., Kaye, W., Berrettini, W., Hakonarson, H., Herpertz-Dahlmann, B., de Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Egberts, K. M. & 19 others, Adan, R., Brandys, M., van Elburg, A., Boraska Perica, V., Franklin, C. S., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., GCAN, Hottenga, J. J., Willemsen, G., Boomsma, D. I., van Beijsterveldt, C. E. M., Middeldorp, C. M. & de Geus, E., Feb 2017, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2019

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B., Jansen, R. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017
2019

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

The EAGLE-ADHD Consortium, 18 Jan 2019, In : Behavior Genetics. 49, 3, p. 1-16 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Posthuma, D., 1 Nov 2019, In : Biological Psychiatry. 88, 2, p. 169-184

Research output: Contribution to JournalArticleAcademicpeer-review

2012

Common variants at 12q15 and 12q24 are associated with infant head circumference

Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Boomsma, D. I., Hakonarson, H., Smith, G. D., Heinrich, J., Jarvelin, M-R. & Jaddoe, V. W. V., 2012, In : Nature Genetics. 44, 5, p. 532-538

Research output: Contribution to JournalArticleAcademicpeer-review

2014

Heritability and genomics of gene expression in peripheral blood

Wright, F. A., Sullivan, P. F., Brooks, A. I., Zou, F., Sun, W., Xia, K., Madar, V., Jansen, R., Chung, W., Zhou, Y. H., Abdellaoui, A., Batista, S., Butler, C., Chen, G., Chen, T. H., D’Ambrosio, D., Gallins, P., Ha, M. J., Hottenga, J. J., Huang, S. & 18 others, Kattenberg, V. M., Kochar, J., Middeldorp, C. M., Qu, A., Shabalin, A., Tischfield, J., Todd, L., Tzeng, J. Y., Grootheest, G., Vink, J. M., Wang, Q., Wang, W., Willemsen, G., Smit, J. H., de Geus, E. J. C., Yin, Z., Penninx, B. W. J. H. & Boomsma, D. I., 2014, In : Nature Genetics. 46, 5, p. 430-437 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2015

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

O’Dushlaine, C., Rossin, L., Lee, P. H., Duncan, L., Parikshak, N. N., Newhouse, S., Ripke, S., Neale, B. M., Purcell, S. M., Posthuma, D., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Krabbendam, A. C., Middeldorp, C. M., Penninx, B. W. J. H., Sergeant, J. A., Smit, J. H., Grootheest, G., Willemsen, G. & 2 others, Holmes, P. & Breen, G., 2015, In : Nature Neuroscience. 18, 2, p. 199-209 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bonnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 130 others, Kalb, B., Pino-Yanes, M., Xu, C., Carstensen, L., Groen-Blokhuis, M. M., Venturini, C., Pennell, C. E., Barton, S. J., Levin, A. M., Curjuric, I., Bustamante, M., Kreiner-Moller, E., Lockett, G. A., Bacelis, J., Bunyavanich, S., Myers, R. A., Matanovic, A., Kumar, A., Tung, J. Y., Hirota, T., Kubo, M., McArdle, W. L., Henderson, A. J., Kemp, J. P., Zheng, J., Smith, G. D., Rueschendorf, F., Bauerfeind, A., Lee-Kirsch, M. A., Arnold, A., Homuth, G., Schmidt, C. O., Mangold, E., Cichon, S., Keil, T., Rodriguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Foelster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L. L., Grarup, N., de Jongste, J. C., Rivadeneira, F., Hofman, A., Jaddoe, V. W. V., Pasmans, S. G. M. A., Elbert, N. J., Uitterlinden, A. G., Marks, G. B., Thompson, P. J., Matheson, M. C., Robertson, C. F., Ried, J. S., Li, J., Zuo, X. B., Zheng, X. D., Yin, X. Y., Sun, L. D., McAleer, M. A., O'Regan, G. M., Fahy, C. M. R., Campbell, L. E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D. S., Feenstra, B., Geller, F., Hottenga, J. J., Middeldorp, C. M., Hysi, P., Bataille, V., Spector, T., Tiesler, C. M. T., Thiering, E., Pahukasahasram, B., Yang, J. J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C. L., Myhre, R., Nystad, W., Custovic, A., Weiss, S. T., Meyers, D. A., Soederhaell, C., Melen, E., Ober, C., Raby, B. A., Simpson, A., Jacobsson, B., Holloway, J. W., Bisgaard, H., Sunyer, J., Probst-Hensch, N. M., Williams, L. K., Godfrey, K. M., Wang, C. A., Boomsma, D. I., Melbye, M., Koppelman, G. H., Jarvis, D., McLean, W. H. I., Irvine, A. D., Zhang, X. J., Hakonarson, H., Gieger, C., Burchard, E. G., Martin, N. G., Duijts, L., Linneberg, A., Jarvelin, M., Noethen, M. M., Lau, S., Huebner, N., Lee, Y., Tamari, M., Hinds, D. A., Glass, D., Brown, S. J., Heinrich, J., Evans, D. M. & Weidinger, S., 2015, In : Nature Genetics. 47, 12, p. 1449-1456

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2014

Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders

Ligthart, L., Hottenga, J. J., Lewis, C. M., Farmer, A. E., Craig, I. W., Breen, G., Willemsen, G., Vink, J. M., Middeldorp, C. M., Byrne, E. M., Heath, A. C., Madden, P. A. F., Pergadia, M. L., Montgomery, G. W., Martin, N. G., Penninx, B. W. J. H., McGuffin, P., Boomsma, D. I. & Nyholt, DR., 2014, In : Human Genetics. 133, 2, p. 173-186 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Attention-Deficit/Hyperactivity Disorder Polygenic Risk Scores Predict Attention Problems in a Population-Based Sample of Children

Blokhuis, M. M., Middeldorp, C. M., Kan, K. J., Abdellaoui, A., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Scheet, P., Xiao, X., Hudziak, J. J., Hottenga, J. J., Neale, B. M. & Boomsma, D. I., 2014, In : Journal of the American Academy of Child and Adolescent Psychiatry. 53, 10, p. 1123-1129 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Further confirmation of the association between anxiety and CTNND2: replication in humans

Nivard, M. G., Mbarek, H., Hottenga, J. J., Smit, J. H., Penninx, B. W. J. H., Middeldorp, C. M. & Boomsma, D. I., 2014, In : Genes, Brain and Behavior. 13, 2, p. 195-201 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Research Review: Polygenic methods and their application to psychiatric traits

Wray, N. R., Lee, S. H., Mehta, D., Vinkhuyzen, A. A. E., Dudbridge, F. & Middeldorp, C. M., 2014, In : Journal of Child Psychology and Psychiatry. 55, 10, p. 1068-1087 20 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2015

Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder

Byrne, E. M., Boomsma, D. I., Martin, N. G., Penninx, B. W. J. H., de Geus, E. J. C., Hoogendijk, W. J. G., Hottenga, J. J., Middeldorp, C. M., Nyholt, DR., Smit, J. H., van den Oord, E. J., Grootheest, G., Willemsen, G., Zitman, F. G., Neale, B. M., Sullivan, P. F., Raheja, U. K., Stephens, S. H., Heath, A. C., Madden, P. A. F. & 11 others, Vaswani, D., Nijjar, G. V., Ryan, K. A., Youssufi, H., Gehrman, P. R., Shuldiner, A. R., Montgomery, G. W., Wray, N. R., Nelson, E. C., Mitchell, B. D. & Postolache, T. T., 2015, In : Journal of Clinical Psychiatry. 76, 2, p. 128-134 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood

Nivard, M. G., Middeldorp, C. M., Dolan, C. V. & Boomsma, D. I., 2015, In : Twin Research and Human Genetics. 18, 6, p. 746-754 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Maier, R., Moser, G., Chen, G. B., Ripke, S., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Coryell, W. H., Potash, J. B., Scheftner, W. A., Shi, J., Weissmann, M. M., Hultman, C. M., Landén, M., Levinson, D. F., Kendler, K. S., Smoller, J. W., Wray, N. R. & 1 others, Lee, S. H., 2015, In : American Journal of Human Genetics. 96, 2, p. 283-294 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height

Fedko, I. O., Hottenga, J. J., Medina-Gomez, C., Pappa, I., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Rivadeneira, F., Tiemeier, H., Swertz, M. A., Middeldorp, C. M., Bartels, M. & Boomsma, D. I., 2015, In : Behavior Genetics. 45, 5, p. 514-528 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017
Open Access
2016

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

Pappa, I., St Pourcain, B., Benke, K. S., Cavadino, A., Hakulinen, C., Nivard, M. G., Nolte, I. M., Tiesler, C. M. T., Bakermans-Kranenburg, M. J., Davies, G. E., Evans, D. M., Geoffroy, M. C., Grallert, H., Blokhuis, M. M., Hudziak, J. J., Kemp, J. P., Keltikangas-Järvinen, L., McMahon, G., Mileva-Seitz, V. R., Motazedi, E. & 23 others, Power, C., Raitakari, O. T., Ring, S. M., Rivadeneira, F., Rodriguez, A., Scheet, P., Seppälä, I., Snieder, H., Standl, M., Thiering, E., Timpson, N. J., Veenstra, R., Velders, F. P., Whitehouse, A. J. O., Davey Smith, G., Heinrich, J., Hypponen, E., Lehtimäki, T., Middeldorp, C. M., Oldehinkel, A. J., Pennell, C. E., Boomsma, D. I. & Tiemeier, H., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 5, p. 562-572

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Discovery of Biochemical Biomarkers for Aggression: A Role for Metabolomics in Psychiatry

Hagenbeek, F. A., Kluft, C., Hankemeier, T., Bartels, M., Draisma, H. H. M., Middeldorp, C. M., Berger, R., Noto, A., Lussu, M., Pool, R., Fanos, V. & Boomsma, D. I., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 5, p. 719-732

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Open Access
2017
Open Access
2013

Angst en depressie van de kindertijd tot in de volwassenheid

Middeldorp, C. M., 2013.

Research output: Contribution to ConferencePosterOther research output

The use of longitudinal data of childhood and adolescent internalizing problems in genetic studies

Middeldorp, C. M., 2013.

Research output: Contribution to ConferencePosterOther research output

2015

The genetic overlap between schizophrenia and childhood psychopathology

Middeldorp, C. M., 2015.

Research output: Contribution to ConferencePosterOther research output

2014

De meerwaarde van een familiepoli

Batelaan, N. M. & Middeldorp, C. M., 2014, In : PsychoPraktijk. 6, 3, p. 14-17 4 p.

Research output: Contribution to JournalArticleProfessional

Behavior Genetics: From Heritability to Gene Finding

Nivard, M. G., Dolan, C. V., Middeldorp, C. M. & Boomsma, D. I., 1 Feb 2017, Handbook of Psychophysiology. Cacioppo, J. T., Tassinary, L. G. & Berntson, G. G. (eds.). 4 ed. Cambridge University Press, p. 339-354 16 p.

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

2019

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee, P. H., Anttila, V., Won, H., Feng, Y., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., Derks, E. M., op Landt Slof, M. C. T., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., W J H Penninx, B., Cath, D. C. & 11 others, Denys, D., Santangelo, S., Scharf, J. M., Stein, M. B., Thornton, L. M., Walters, J. T. R., Wray, N. R., Geschwind, D. H., Neale, B. M., Kendler, K. S. & Smoller, J. W., 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11 26 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
2018

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 20 Dec 2018, In : PLoS ONE. 13, 12, p. 1-29 29 p., e0209160.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2012

Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data

Brandys, M. K., Slof-Op 't Landt, M. C. T., van Elburg, A. A., Ophoff, R. A., Verduijn, W., Meulenbelt, I., Middeldorp, C. M., Boomsma, D. I., van Furth, E. F., Slagboom, P. E., Kas, M. J. H. & Adan, R. A. H., 2012, In : Psychiatric Genetics. 22, 3, p. 130-136

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

Webb, B. T., Guo, A. Y., Maher, B. S., Zhao, Z., van den Oord, E. J., Kendler, K. S., Riley, B. P., Gillespie, N. A., Prescott, C. A., Middeldorp, C. M., Willemsen, G., de Geus, E. J. C., Hottenga, J. J., Boomsma, D. I., Slagboom, P. E., Wray, N. R., Montgomery, G. W., Martin, N. G., Wright, M. J., Heath, A. C. & 15 others, Madden, P. A. F., Gelernter, J., Knowles, J. A., Hamilton, S. P., Weissman, M. M., Fyer, A. J., Huezo-Diaz, P., McGuffin, P., Farmer, A., Craig, I. W., Lewis, C., Sham, P., Crowe, R. R., Flint, J. & Hettema, J. M., 2012, In : European Journal of Human Genetics. 20, 10, p. 1078-1084

Research output: Contribution to JournalArticleAcademicpeer-review

2018
2012

Sex Differences in Genetic Architecture of Complex Phenotypes?

Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M., van Dongen, J., van Beek, J. H. D. A., Distel, M. A., de Moor, M. H. M., Smit, D. J. A., Minica, C. C., Ligthart, L., Geels, L. M., Abdellaoui, A., Middeldorp, C. M., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Boomsma, D. I., 2012, In : PLoS ONE. 7, 12, e47371.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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