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Author

  • Lannie Ligthart
2019

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

BBMRI Metabolomics Consortium, 16 Apr 2019, In : Neurology. 92, 16, p. e1899-e1911 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2014

Comorbidity among multiple pain symptoms and anxious depression in a Dutch population sample

Ligthart, L., Visscher, C. M., van Houtem, C. M. H. H., Geels, L. M., Vink, J. M., de Jongh, A. & Boomsma, D. I., 2014, In : Journal of Pain. 15, 9, p. 945-955 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders

Ligthart, L., Hottenga, J. J., Lewis, C. M., Farmer, A. E., Craig, I. W., Breen, G., Willemsen, G., Vink, J. M., Middeldorp, C. M., Byrne, E. M., Heath, A. C., Madden, P. A. F., Pergadia, M. L., Montgomery, G. W., Martin, N. G., Penninx, B. W. J. H., McGuffin, P., Boomsma, D. I. & Nyholt, DR., 2014, In : Human Genetics. 133, 2, p. 173-186 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Is dental phobia a blood-injection-injury phobia?

van Houtem, C. M. H. H., Aartman, I. H. A., Boomsma, D. I., Ligthart, L., Visscher, C. & de Jongh, A., 2014, In : Depression and Anxiety. 31, 12, p. 1026-1034 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2015

Self-reported gagging in dentistry: prevalence, psycho-social correlates and oral health

van Houtem, C. M. H. H., van Wijk, A. J., Boomsma, D. I., Ligthart, L., Visscher, C. M. & de Jongh, A., 2015, In : Journal of Oral Rehabilitation. 42, 7, p. 487-494 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2010

Prevalence and heritability of early-onset migraine

Ligthart, L., van der Aa, N., Bartels, M. & Boomsma, D. I., 2010.

Research output: Contribution to ConferencePosterOther research output

Prevalence and heritability of early-onset migraine

Ligthart, L., van der Aa, N., Bartels, M. & Boomsma, D. I., 2010, In : Twin Research and Human Genetics. 13, 3, p. 272-273

Research output: Contribution to JournalMeeting AbstractOther research output

2018

DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis

Ward-Caviness, C. K., Huffman, J. E., Everett, K., Germain, M., Van Dongen, J., Hill, W. D., Jhun, M. A., Brody, J. A., Ghanbari, M., Du, L., Roetker, N. S., De Vries, P. S., Waldenberger, M., Gieger, C., Wolf, P., Prokisch, H., Koenig, W., O’Donnell, C. J., Levy, D., Liu, C. & 34 others, Truong, V., Wells, P. S., Trégouët, D. A., Tang, W., Morrison, A. C., Boerwinkle, E., Wiggins, K. L., McKnight, B., Guo, X., Psaty, B. M., Sotoodenia, N., Boomsma, D. I., Willemsen, G., Ligthart, L., Deary, I. J., Zhao, W., Ware, E. B., Kardia, S. L. R., Van Meurs, J. B. J., Uitterlinden, A. G., Franco, O. H., Eriksson, P., Franco-Cereceda, A., Pankow, J. S., Johnson, A. D., Gagnon, F., Morange, P. E., De Geus, E. J. C., Starr, J. M., Smith, J. A., Dehghan, A., Björck, H. M., Smith, N. L. & Peters, A., 25 Oct 2018, In : Blood. 132, 17, p. 1842-1850 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2019
Open Access
2012

Sex Differences in Genetic Architecture of Complex Phenotypes?

Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M., van Dongen, J., van Beek, J. H. D. A., Distel, M. A., de Moor, M. H. M., Smit, D. J. A., Minica, C. C., Ligthart, L., Geels, L. M., Abdellaoui, A., Middeldorp, C. M., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Boomsma, D. I., 2012, In : PLoS ONE. 7, 12, e47371.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
2013

Genome-wide meta-analysis identifies new susceptibility loci for migraine

Anttila, V., Winsvold, B. S., Gormley, P., Kurth, T., Bettella, F., McMahon, G., Kallela, M., Malik, R., de Vries, B., Terwindt, G., Medland, S. E., Todt, U., McArdle, W. L., Quaye, L., Koiranen, M., Ikram, M. A., Lehtimäki, T., Stam, A. H., Ligthart, L., Wedenoja, J. & 75 others, Dunham, I., Neale, B. M., Palta, P., Hamalainen, E., Schürks, M., Rose, L. M., Buring, J. E., Ridker, P. M., Steinberg, S., Stefansson, H., Jakobsson, F., Lawlor, D. A., Evans, D. M., Ring, S. M., Färkkilä, M., Artto, V., Kaunisto, M. A., Freilinger, T., Schoenen, J., Frants, R. R., Pelzer, N., Weller, C. M., Zielman, R., Heath, A. C., Madden, P. A. F., Montgomery, G. W., Martin, N. G., Borck, G., Göbel, H., Heinze, A., Heinze-Kuhn, K., Williams, F. M., Hartikainen, A-L., Pouta, A., van den Ende, J., Uitterlinden, A. G., Hofman, A., Amin, N., Hottenga, J. J., Vink, J. M., Heikkilä, K., Alexander, M., Muller-Myhsok, B., Schreiber, S., Meitinger, T., Wichmann, H. E., Aromaa, A., Eriksson, J. G., Traynor, B. J., Trabzuni, D., Rossin, E., Lage, K., Jacobs, S. B., Gibbs, J. R., Birney, E., Kaprio, J., Penninx, B. W. J. H., Boomsma, D. I., van Duijn, C. M., Raitakari, O., Jarvelin, M-R., Zwart, J. A., Cherkas, L., Strachan, D. P., Kubisch, C., Ferrari, M. D., van den Maagdenberg, A. M. J. M., Dichgans, M., Wessman, M., Smith, G. D., Stefansson, K., Daly, M. J., Nyholt, DR., Chasman, D. I. & Palotie, A., 2013, In : Nature Genetics. 45, 8, p. 912-917

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

A review and meta-analysis of the heritability of specific phobia subtypes and corresponding fears

van Houtem, C. M. H. H., Laine, M. L., Boomsma, D. I., Ligthart, L., van Wijk, A. J. & de Jongh, A., 2013, In : Journal of Anxiety Disorders. 27, 4, p. 379-388

Research output: Contribution to JournalArticleAcademicpeer-review

2011

Meta-analysis of genome-wide association for migraine in six population-based European cohorts

Ligthart, L., de Vries, B., Smith, A. V., Arfan Ikram, M., Amin, N., Hottenga, J. J., Koelewijn, S. C., Kattenberg, V. M., de Moor, M. H. M., Janssens, A. J. W., Aulchenko, Y. S., Oostra, B. A., de Geus, E. J. C., Smit, J. H., Zitman, F. G., Uitterlinden, A. G., Hofman, A., Willemsen, G., Nyholt, DR., Montgomery, G. W. & 9 others, Terwindt, G. M., Gudnason, V., Penninx, B. W. J. H., Breteler, M., Ferrari, M. D., Launer, L. J., van Duijn, C. M., van den Maagdenberg, A. M. J. M. & Boomsma, D. I., 2011, In : European Journal of Human Genetics. 19, 8, p. 901-907

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

Prevalence of dieting and fear of weight gain across ages: a community sample from adolescents to the elderly

Slof-Op 't Landt, M. C. T., van Furth, E. F., van Beijsterveldt, C. E. M., Bartels, M., Willemsen, G., de Geus, E. J., Ligthart, L. & Boomsma, D. I., 1 Nov 2017, In : International Journal of Public Health. 62, 8, p. 911-919 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2010

The shared genetics of migraine and anxious depression

Ligthart, L., Nijholt, D. R., Penninx, B. W. J. H. & Boomsma, D. I., 2010, In : Headache. 50, 10, p. 1549-1560

Research output: Contribution to JournalArticleAcademicpeer-review

2017

Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank

Reus, L. M., Shen, X., Gibson, J., Wigmore, E., Ligthart, L., Adams, M. J., Davies, G., Cox, S. R., Hagenaars, S. P., Bastin, M. E., Deary, I. J., Whalley, H. C. & McIntosh, A. M., 10 Feb 2017, In : Scientific Reports. 7, 42140.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2019

Does genetic risk of insomnia influence aggression?

Lavender, R., Allegrini, A., Bolhuis, K., Hagenbeek, F., Palviainen, T., Bartels, M., Boomsma, D., Fedko, I., Hottenga, J-J., Kaprio, J., Koopman-Verhoeff, M. E., Korhonen, T., Lamballais, S., Ligthart, L., Rimfeld, K., Tiemeier, H., van Beijsterveldt, T., Vuoksimaa, E., Whipp, A., Martin, N. & 2 others, Colodro-Conde, L. & Medland, S., Nov 2019, In : Behavior Genetics. 49, 6, p. 516-517

Research output: Contribution to JournalMeeting AbstractAcademic

2018

Molecular genetic overlap between migraine and major depressive disorder

The International Headache Genetics Consortium, 1 Aug 2018, In : European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Shared Genetics of Temporomandibular Disorder Pain and Neck Pain: Results of a Twin Study

Visscher, C. M., Schouten, M. J., Ligthart, L., van Houtem, C. M., de Jongh, A. & Boomsma, D. I., Apr 2018, In : Journal of oral & facial pain and headache. 32, 2, p. 107-112 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2017

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 93 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A., Hottenga, J-J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., 13 Oct 2017, In : Nature Communications. 8, 1, p. 910 910.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2018

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

Boomsma, D. I., Ligthart, L., Posthuma, D. & 23Andme Research Team, 16 May 2018, In : Neuron. 98, 4, p. 743-753.e4

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
2015

Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants

Malik, R., Freilinger, T., Winsvold, B. S., Anttila, V., van der Heiden, J., Traylor, M., de Vries, B., Holliday, E. G., Terwindt, G. M., Sturm, J., Bis, J. C., Hopewell, J. C., Ferrari, M. D., Rannikmae, K., Wessman, M., Kallela, M., Kubisch, C., Fornage, M., Meschia, J. F., Lehtimäki, T. & 32 others, Sudlow, C., Clarke, R., Chasman, D. I., Mitchell, B. D., Maguire, J., Kaprio, J., Farrall, M., Raitakari, O. T., Kurth, T., Arfan Ikram, M., Reiner, A. P., Longstreth, J. W. T., Rothwell, P. M., Strachan, D. P., Sharma, P., Seshadri, S., Quaye, L., Cherkas, L., Schürks, M., Rosand, J., Ligthart, L., Boncoraglio, G. B., Davey Smith, G., van Duijn, C. M., Stefansson, K., Worrall, B. B., Nyholt, DR., Markus, H. S., van den Maagdenberg, A. M. J. M., Cotsapas, C., Zwart, J. A. & Palotie, A., 2015, In : Neurology. 84, 21, p. 2132-2145

Research output: Contribution to JournalArticleAcademicpeer-review

2010

Genetic covariance structure of the four main features of borderline personality disorder

Distel, M. A., Willemsen, G., Ligthart, L., Derom, C. A., Martin, N. G., Neale, M. C., Trull, T. J. & Boomsma, D. I., 2010, In : Journal of Personality Disorders. 24, 4, p. 427-444

Research output: Contribution to JournalArticleAcademicpeer-review

2011

Qualitative and quantitative sex differences in genetic architecture for human phenotypes

Boomsma, D. I., Bartels, M., van Beijsterveldt, C. E. M., Distel, M. A., Smit, D. J. A., de Moor, M. H. M., Middeldorp, M., Ligthart, R. S. L., Willemsen, G., Hottenga, J. J., de Geus, E. J. C. & Vink, J. M., 2011, In : Behavior Genetics. 41, 6, p. 894-895

Research output: Contribution to JournalMeeting AbstractOther research output

Open Access
File
2017

Heritability of tic disorders: a twin-family study

Rodrigues Zilhao Nogueira, N., Olthof, M. C., Smit, D. J. A., Cath, D. C., Ligthart, L., Mathews, C. A., Delucchi, K., Boomsma, D. I. & Dolan, C. V., Mar 2017, In : Psychological Medicine. 47, 6, p. 1085-1096 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2018
Open Access

Dopaminergic Genetic Variants and Voluntary Externally Paced Exercise Behavior

Van Der Mee, D. J., Fedko, I. O., Hottenga, J. J., Ehli, E. A., Van Der Zee, M. D., Ligthart, L., Van Beijsterveldt, T. C. E. M., Davies, G. E., Bartels, M., Landers, J. G. & De Geus, E. J. C., Apr 2018, In : Medicine and Science in Sports and Exercise. 50, 4, p. 700-708 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
2017

Genome-Wide Significance for PCLO as a Gene for Major Depressive Disorder

Mbarek, H., Milaneschi, Y., Hottenga, J-J., Ligthart, L., de Geus, E. J. C., Ehli, E. A., Willemsen, G., Davies, G. E., Smit, J. H., Boomsma, D. I. & Penninx, B. W. J. H., 1 Aug 2017, In : Twin Research and Human Genetics. 20, 4, p. 267-270 4 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2018
Open Access
2013

The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection

Willemsen, G., Vink, J. M., Abdellaoui, A., den Braber, A., van Beek, J. H. D. A., Draisma, H. H. M., van Dongen, J., van t Ent, D., Geels, L. M., van Lien, R., Ligthart, L., Kattenberg, V. M., Mbarek, H., de Moor, M. H. M., Neijts, M., Pool, R., Stroo, N., Kluft, C., Suchiman, H. E. D., Slagboom, P. E. & 2 others, de Geus, E. J. C. & Boomsma, D. I., 2013, In : Twin Research and Human Genetics. 16, 1, p. 271-281

Research output: Contribution to JournalArticleAcademicpeer-review

2014

Genetisch onderzoek met behulp van tweelingen

Ligthart, L., 2014, In : Quality Practice. Nascholingstijdschrift voor tandartsen. 9, 5, p. 8-11 4 p.

Research output: Contribution to JournalArticleProfessional

2015

Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder

Jacobsen, K. K., Nievergelt, C. M., Zayats, T., Greenwood, T. A., Anttila, V., Akiskal, H. S., Ligthart, L., Hottenga, J. J., Vink, J. M., Penninx, B. W. J. H., Boomsma, D. I., Haavik, J., Fasmer, O. B., Kelsoe, J. R., Johansson, S. & Oedegaard, K. J., 2015, In : Journal of Affective Disorders. 172, p. 453-461 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2018

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, 22 Jun 2018, In : Science. 360, 6395, p. 1-15 15 p., 8757.

Research output: Contribution to JournalArticleAcademicpeer-review

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23Andme Research Team, 26 Nov 2018, In : Nature Neuroscience. 21, 12, p. 1656-1669 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2015

Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies

Nyholt, DR., Anttila, V., Winsvold, B. S., Kurth, T., Stefansson, H., Kallela, M., Malik, R., de Vries, B., Terwindt, G. M., Arfan Ikram, M., Stam, A. H., Ligthart, L., Freilinger, T., Alexander, M., Müller-Myhsok, B., Schreiber, S., Meitinger, T., Aromaa, A., Eriksson, J. G., Kaprio, J. & 16 others, Boomsma, D. I., van Duijn, C. M., Raitakari, O. T., Järvelin, M. R., Zwart, J. A., Quaye, L., Strachan, D. P., Kubisch, C., Ferrari, M. D., van den Maagdenberg, A. M. J. M., Dichgans, M., Wessman, M., Davey Smith, G., Stefansson, K., Chasman, D. I. & Palotie, A., 2015, In : Cephalalgia. 35, 6, p. 489-499 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Epigenome-Wide Association Study of Aggressive Behavior

van Dongen, J., Nivard, M. G., Baselmans, B. M. L., Rodrigues Zilhao Nogueira, N., Ligthart, L., Heijmans, B. T., Bartels, M. & Boomsma, D. I., 2015, In : Twin Research and Human Genetics. 18, 6, p. 686-698 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2012
2013

Anxiety and Depression Are Associated With Migraine and Pain in General: An Investigation of the Interrelationships

Ligthart, L., Gerrits, M. J. G., Boomsma, D. I. & Penninx, B. W. J. H., 2013, In : Journal of Pain. 14, 4, p. 363-370

Research output: Contribution to JournalArticleAcademicpeer-review

Is tmd-pijn erfelijk?

Visscher, C. M., Ligthart, L. & Lobbezoo, F., 2013, In : Quality Practice. Nascholingstijdschrift voor tandartsen. 8, 4, p. 12-14

Research output: Contribution to JournalArticleProfessional

2014

Prevalence and comorbidity of pain symptoms in the general population

Ligthart, L., 2014.

Research output: Contribution to ConferencePosterOther research output

2011

Migraine, depression and other types of pain: a common etiology?

Ligthart, L., 2011.

Research output: Contribution to ConferencePosterOther research output

2017
2018

An Extended Twin-Pedigree Study of Neuroticism in the Netherlands Twin Register

Boomsma, D. I., Helmer, Q., Nieuwboer, H. A., Hottenga, J. J., de Moor, M. H., van den Berg, S. M., Davies, G. E., Vink, J. M., Schouten, M. J., Dolan, C. V., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Ligthart, L. & de Geus, E. J., 1 Jan 2018, In : Behavior Genetics. 48, 1, p. 1-11

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2019

Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies

Doering, S., Lichtenstein, P., Gillberg, C., Boomsma, D. I., Van Beijsterveldt, T. C. E. M., Ligthart, L., Willemsen, G., De Geus, E., Middeldorp, C. M., Bartels, M., Kuja-Halkola, R. & Lundström, S., 14 Nov 2019, In : BMC Psychiatry. 19, 1, p. 1-11 11 p., 363.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2010

Relationships between trait emotional intelligence and the Big Five in the Netherlands

Petrides, K. V., Vernon, P. A., Schermer, J. A., Ligthart, L., Boomsma, D. I. & Veselka, L., 2010, In : Personality and Individual Differences. 48, 8, p. 906-910

Research output: Contribution to JournalArticleAcademicpeer-review

Childhood and Adolescent Anxiety and Depression: Beyond Heritability

Franic, S., Middeldorp, C. M., Dolan, C. V., Ligthart, L. & Boomsma, D. I., 2010, In : Journal of the American Academy of Child and Adolescent Psychiatry. 49, 8, p. 820-829

Research output: Contribution to JournalArticleAcademicpeer-review

Migraine symptomatology and major depressive disorder

Ligthart, L., Penninx, B. W. J. H., Nijholt, D. R., Distel, M. A., de Geus, E. J. C., Willemsen, G., Smit, J. H. & Boomsma, D. I., 2010, In : Cephalalgia. 30, 9, p. 1073-1081

Research output: Contribution to JournalArticleAcademicpeer-review

2017

Short communication: Genetic association between schizophrenia and cannabis use

Verweij, C. J. H., Abdellaoui, A., Nivard, M. G., Sainz Cort, A., Ligthart, L., Draisma, H. H. M., Minica, C. C., International Cannabis Consortium, Willemsen, G., Hottenga, J. J., Boomsma, D. I. & Vink, J. M., 1 Feb 2017, In : Drug and Alcohol Dependence. 171, p. 117-121 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2010

The Genetics and Comorbidity of Migraine

Ligthart, R. S. L., 2010, Amsterdam. 268 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VU

Open Access
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