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Author

  • C.M. Middeldorp
2011

De invloed van genen en omgeving op de ontwikkeling van angststoornissen

Middeldorp, C. M. & Cath, D. C., 2011, Handboek angststoornissen. van Balkom, A. J. L. M., Oosterbaan, D., Visser, S. & van Vliet, I. M. (eds.). Utrecht: De Tijdstroom, p. 287-302 15 p.

Research output: Chapter in Book / Report / Conference proceedingChapterAcademic

2014

Interview

Middeldorp, C. M., 1 May 2014, In : Nieuwsbrief Fonds Psychische Gezondheid.

Research output: Contribution to JournalArticlePopular

2015

Genetica en psychische stoornissen op de kinderleeftijd: erfelijkheid en de zoektocht naar genen

Middeldorp, C. M., 2015, In : Tijdschrift voor Psychiatrie. 57, 12, p. 876-880 5 p.

Research output: Contribution to JournalArticleProfessional

2010

Heritability of anxious-depressive and withdrawn behavior: Age-related changes during adolescence

Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M., Bartels, M., van der Aa, N., Polderman, T. J. C. & Boomsma, D. I., 2010, In : Journal of the American Academy of Child and Adolescent Psychiatry. 49, 3, p. 248-255

Research output: Contribution to JournalArticleAcademicpeer-review

2011

Genome-wide complex trait analysis (gcta) for complex traits including major depressive disorder and smoking

Boomsma, D. I., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Lubke, G. H., 2011.

Research output: Contribution to ConferencePosterOther research output

2012

Maternal prenatal smoking and offspring emotional problems: No moderating effect of maternal or child 5-HTTLPR genotype

Geels, L. M., Groen-Blokhuis, M. M., van Beijsterveldt, C. E. M., Vink, J. M., Middeldorp, C. M., Bartels, M., Nelson, K. A., Huizenga, P. E., Davies, G. E. & Boomsma, D. I., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 8, p. 1009-1012

Research output: Contribution to JournalArticleAcademicpeer-review

2018
2012

Sex Differences in Genetic Architecture of Complex Phenotypes?

Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M., van Dongen, J., van Beek, J. H. D. A., Distel, M. A., de Moor, M. H. M., Smit, D. J. A., Minica, C. C., Ligthart, L., Geels, L. M., Abdellaoui, A., Middeldorp, C. M., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Boomsma, D. I., 2012, In : PLoS ONE. 7, 12, e47371.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Genome-Wide Association Uncovers Shared Genetic Effects Among Personality Traits and Mood States

Luciano, M., Huffman, J. E., Arias-Vasquez, A., Vinkhuyzen, A. A. E., Middeldorp, C. M., Giegling, I., Payton, A., Davies, G. E., Zgaga, L., Janzing, J. G., Ke, X. Y., Galesloot, T., Hartmann, A. M., Ollier, W., Tenesa, A., Hayward, C., Verhagen, M., Montgomery, G. W., Hottenga, J. J., Konte, B. & 24 others, Starr, J. M., Vitart, V., Vos, P. E., Madden, P. A. F., Willemsen, G., Konnerth, H., Horan, M. A., Porteous, D. J., Campbell, H., Vermeulen, S. H., Heath, A. C., Wright, A., Polasek, O., Kovacevic, S. B., Hastie, N., Franke, B., Boomsma, D. I., Martin, N. G., Rujescu, D., Wilson, J. F., Buitelaar, J., Pendleton, N., Rudan, I. & Deary, I. J., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 6, p. 684-695

Research output: Contribution to JournalArticleAcademicpeer-review

2013

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth pubertal timing and childhood adiposity

Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., Groen-Blokhuis, M. M., Kreiner-Møller, E., Marinelli, M., Holst, C., Leinonen, J. T., Perry, J. R., Surakka, I., Pietilainen, O. P., Kettunen, J., Anttila, V. & 269 others, Kaakinen, M., Sovio, U., Pouta, A., Das, S., Lagou, V., Power, C., Prokopenko, I., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Palotie, A., Kajantie, E., Osmond, C., Lehtimäki, T., Viikari, J. S., Kähönen, M., Warrington, N. M., Lye, S. J., Palmer, L. J., Tiesler, C. M. T., Flexeder, C., Montgomery, G. W., Medland, S. E., Hofman, A., Hakonarson, H., Guxens, M., Bartels, M., Salomaa, V., Adair, L. S., Atalay, M., van Beijsterveldt, C. E. M., Bergen, N., Benke, K. S., Charoen, P., Coin, L., Cooper, C., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Feenstra, B., Frayling, T. M., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M. W., Goh, L. K., Hattersley, A. T., Haworth, C. M., Hadley, D., Hedebrand, J., Hinney, A., Hirschhorn, J. N., Hocher, B., Holloway, J. W., Hottenga, J. J., Horikoshi, M., Iñiguez, C., Järvelin, M. R., Kilpeläinen, T. O., Kirin, M., Kowgier, M., Lakka, H. M., Lakka, T. A., Lange, L. A., Lawlor, D. A., Lewin, A., Lindgren, C. M., Lindi, V., Maggi, R., Marsh, J., Melbye, M., Middeldorp, C. M., Millwood, I., Mohlke, K. L., Mook-Kanamori, D. O., Murray, J. C., Nivard, M. G., Nohr, E. A., Ntalla, I., Oken, E., Ong, K. K., O'Reilly, P. F., Panoutsopoulou, K., Pararajasingham, J., Pearson, E. R., Price, T. S., Rodriguez, A., Salem, R. M., Saw, S. M., Scherag, A., Sebert, S., Siitonen, N., Simell, O., Strachan, D. P., Sunyer, J., Teo, Y. Y., Uitterlinden, A. G., Valcárcel, B., White, S., Widén, E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zeggini, E., Elks, C. E., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Gudbjartsson, D. F., Esko, T., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K. E., Smith, E. N., Ulivi, S., Warrington, M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Coviello, A. D., d'Adamo, P., de Faire, U., de Geus, E. J. C., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hu, F. B., Illig, T., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., McArdle, W. L., Mooser, V., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Porcu, E., Rafnar, T., Rice, J. P., Rivadeneira, F., Rudan, I., Sala, C., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V., Shuldiner, A. R., Soranzo, N., Srinivasan, S. R., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D., Weedon, M. N., Wichmann, H. E., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Murray, A., Murabito, J. M., Kaprio, J., Sørensen, T. I. A., Ballester, F., Bisgaard, H., Boomsma, D. I., Koppelman, G. H., Grant, S. F., Jaddoe, V. W., Martin, N. G., Heinrich, J., Raitakari, O. T., Eriksson, J. G., Smith, G. D., Hyppönen, E., McCarthy, M. I. & Ripatti, S., 2013, In : Human Molecular Genetics. 22, 13, p. 2735-2747

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The Val66Met polymorphism of the BDNF gene in anorexia nervosa: New data and a meta-analysis

Brandys, M. K., Kas, M. J. H., van Elburg, A. A., Ophoff, R. A., Slof-Op 't Landt, M. C. T., Middeldorp, C. M., Boomsma, D. I., van Furth, E. F., Slagboom, P. E. & Adan, R. A. H., 2013, In : World Journal of Biological Psychiatry. 14, 6, p. 441-451

Research output: Contribution to JournalArticleAcademicpeer-review

2012

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

Wray, N. R., Pergadia, M. L., Blackwood, D. H., Penninx, B. W. J. H., Gordon, S. D., Nyholt, DR., Ripke, S., MacIntyre, D. J., McGhee, K. A., Maclean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., de Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., van den Oord, E. J. C. G., Liu, J. Z. & 12 others, Macgregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Madden, P. A. F. & Sullivan, P. F., 2012, In : Molecular Psychiatry. 17, 1, p. 36-48

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2013

The Young Netherlands Twin Register (YNTR): Longitudinal Twin and Family Studies in Over 70,000 Children

van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Franic, S., Hudziak, J. J., Lamb, D. J., Huppertz, C., de Zeeuw, E. L., Nivard, M. G., Schutte, N. M., Swagerman, S. C., Glasner, T. J., van Fulpen, M. J., Brouwer, C. D., Stroet, T. M., Nowotny, D., Ehli, E. A., Davies, G. E., Scheet, P., Orlebeke, J. F., Kan, K. J. & 6 others, Smit, D. J. A., Dolan, C. V., Middeldorp, C. M., de Geus, E. J. C., Bartels, M. & Boomsma, D. I., 2013, In : Twin Research and Human Genetics. 16, 1, p. 252-267

Research output: Contribution to JournalArticleAcademicpeer-review

Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

Peyrot, W., Middeldorp, C. M., Jansen, R., Smit, J. H., de Geus, E. J. C., Hottenga, J. J., Willemsen, G., Vink, J. M., Virding, S., Barragan, I., Ingelman-Sundberg, M., Sim, S. C., Boomsma, D. I. & Penninx, B. W. J. H., 2013, In : Journal of Affective Disorders. 146, 1, p. 91-99

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2012

Common variants at 12q15 and 12q24 are associated with infant head circumference

Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Boomsma, D. I., Hakonarson, H., Smith, G. D., Heinrich, J., Jarvelin, M-R. & Jaddoe, V. W. V., 2012, In : Nature Genetics. 44, 5, p. 532-538

Research output: Contribution to JournalArticleAcademicpeer-review

2017
Open Access
2015

Analysis of Behavioral and Emotional Problems in Children Highlights the Role of Genotype 9 Environment Interaction

Molenaar, D., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2015, In : Child Development. 86, 6, p. 1999-2016 18 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood

Nivard, M. G., Middeldorp, C. M., Dolan, C. V. & Boomsma, D. I., 2015, In : Twin Research and Human Genetics. 18, 6, p. 746-754 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2010

Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

Middeldorp, C. M., Slof-Op 't Landt, M. C. T., Medland, S. E., van Beijsterveldt, C. E. M., Bartels, M., Willemsen, G., Hottenga, J. J., de Geus, E. J. C., Suchiman, H. E. D., Dolan, C. V., Neale, M. C., Slagboom, P. E. & Boomsma, D. I., 2010, In : Genes, Brain and Behavior. 9, 6, p. 808-816

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2011

The Impact of Environmental Experiences on Symptoms of Anxiety and Depression Across the Life Span

Kendler, K. S., Eaves, L. J., Loken, E. K., Pedersen, N. L., Middeldorp, C. M., Reynolds, C., Boomsma, D. I., Lichtenstein, P., Silberg, J. & Gardner, C. O., 2011, In : Psychological Science. 22, 10, p. 1343-1352

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

Demirkan, A., Penninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlinden, A. G., Hottenga, J. J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. & 1 others, Middeldorp, C. M., 2011, In : Molecular Psychiatry. 16, 7, p. 773-783

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017

Validity of LIDAS (LIfetime Depression Assessment Self-report): a self-report online assessment of lifetime major depressive disorder

Bot, M., Middeldorp, C. M., de Geus, E. J. C., Lau, H. M., Sinke, S. M., van Nieuwenhuizen, B., Smit, J. H., Boomsma, D. I. & Penninx, B. W. J. H., Jan 2017, In : Psychological Medicine. 47, 2, p. 279-289 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2014

A Genome-wide Association Meta-analysis of Preschool Internalizing Problems

Benke, K. S., Nivard, M. G., Velders, F. P., Walters, R. K., Pappa, I., Scheet, P., Xiao, X., Ehli, E. A., Palmer, L. J., Whitehouse, A. J. O., Verhulst, F. C., Jaddoe, V. W., Rivadeneira, F., Blokhuis, M. M., van Beijsterveldt, C. E. M., Davies, G. E., Hudziak, J. J., Lubke, G. H., Boomsma, D. I., Pennell, C. E. & 2 others, Tiemeier, H. & Middeldorp, C. M., 2014, In : Journal of the American Academy of Child and Adolescent Psychiatry. 53, 6, p. 667-676 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders

Ligthart, L., Hottenga, J. J., Lewis, C. M., Farmer, A. E., Craig, I. W., Breen, G., Willemsen, G., Vink, J. M., Middeldorp, C. M., Byrne, E. M., Heath, A. C., Madden, P. A. F., Pergadia, M. L., Montgomery, G. W., Martin, N. G., Penninx, B. W. J. H., McGuffin, P., Boomsma, D. I. & Nyholt, DR., 2014, In : Human Genetics. 133, 2, p. 173-186 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2018
Open Access
2017

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T. M., McGrath, J., Hickie, I. B., Hansell, N. K., Wright, M. J., Gillespie, N. A., Forstner, A. J., Schulze, T. G., Wüst, S., Nöthen, M. M., Baumgartner, M. R., Walker, B. R., Crawford, A. A. & 12 others, Colodro-Conde, L., Medland, S. E., Martin, N. G., Rietschel, M., CORtisolNETwork (CORNET) Consortium, Abdellaoui, A., de Geus, E., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Willemsen, G. & Boomsma, D. I., 10 Nov 2017, In : Scientific Reports. 7, 1, p. 15351 15351.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2015

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bonnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 130 others, Kalb, B., Pino-Yanes, M., Xu, C., Carstensen, L., Groen-Blokhuis, M. M., Venturini, C., Pennell, C. E., Barton, S. J., Levin, A. M., Curjuric, I., Bustamante, M., Kreiner-Moller, E., Lockett, G. A., Bacelis, J., Bunyavanich, S., Myers, R. A., Matanovic, A., Kumar, A., Tung, J. Y., Hirota, T., Kubo, M., McArdle, W. L., Henderson, A. J., Kemp, J. P., Zheng, J., Smith, G. D., Rueschendorf, F., Bauerfeind, A., Lee-Kirsch, M. A., Arnold, A., Homuth, G., Schmidt, C. O., Mangold, E., Cichon, S., Keil, T., Rodriguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Foelster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L. L., Grarup, N., de Jongste, J. C., Rivadeneira, F., Hofman, A., Jaddoe, V. W. V., Pasmans, S. G. M. A., Elbert, N. J., Uitterlinden, A. G., Marks, G. B., Thompson, P. J., Matheson, M. C., Robertson, C. F., Ried, J. S., Li, J., Zuo, X. B., Zheng, X. D., Yin, X. Y., Sun, L. D., McAleer, M. A., O'Regan, G. M., Fahy, C. M. R., Campbell, L. E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D. S., Feenstra, B., Geller, F., Hottenga, J. J., Middeldorp, C. M., Hysi, P., Bataille, V., Spector, T., Tiesler, C. M. T., Thiering, E., Pahukasahasram, B., Yang, J. J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C. L., Myhre, R., Nystad, W., Custovic, A., Weiss, S. T., Meyers, D. A., Soederhaell, C., Melen, E., Ober, C., Raby, B. A., Simpson, A., Jacobsson, B., Holloway, J. W., Bisgaard, H., Sunyer, J., Probst-Hensch, N. M., Williams, L. K., Godfrey, K. M., Wang, C. A., Boomsma, D. I., Melbye, M., Koppelman, G. H., Jarvis, D., McLean, W. H. I., Irvine, A. D., Zhang, X. J., Hakonarson, H., Gieger, C., Burchard, E. G., Martin, N. G., Duijts, L., Linneberg, A., Jarvelin, M., Noethen, M. M., Lau, S., Huebner, N., Lee, Y., Tamari, M., Hinds, D. A., Glass, D., Brown, S. J., Heinrich, J., Evans, D. M. & Weidinger, S., 2015, In : Nature Genetics. 47, 12, p. 1449-1456

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder

Byrne, E. M., Boomsma, D. I., Martin, N. G., Penninx, B. W. J. H., de Geus, E. J. C., Hoogendijk, W. J. G., Hottenga, J. J., Middeldorp, C. M., Nyholt, DR., Smit, J. H., van den Oord, E. J., Grootheest, G., Willemsen, G., Zitman, F. G., Neale, B. M., Sullivan, P. F., Raheja, U. K., Stephens, S. H., Heath, A. C., Madden, P. A. F. & 11 others, Vaswani, D., Nijjar, G. V., Ryan, K. A., Youssufi, H., Gehrman, P. R., Shuldiner, A. R., Montgomery, G. W., Wray, N. R., Nelson, E. C., Mitchell, B. D. & Postolache, T. T., 2015, In : Journal of Clinical Psychiatry. 76, 2, p. 128-134 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2014

Attention-Deficit/Hyperactivity Disorder Polygenic Risk Scores Predict Attention Problems in a Population-Based Sample of Children

Blokhuis, M. M., Middeldorp, C. M., Kan, K. J., Abdellaoui, A., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Scheet, P., Xiao, X., Hudziak, J. J., Hottenga, J. J., Neale, B. M. & Boomsma, D. I., 2014, In : Journal of the American Academy of Child and Adolescent Psychiatry. 53, 10, p. 1123-1129 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2018

Childhood aggression and the co-occurrence of behavioural and emotional problems: results across ages 3–16 years from multiple raters in six cohorts in the EU-ACTION project

Bartels, M., Hendriks, A., Mauri, M., Krapohl, E., Whipp, A., Bolhuis, K., Conde, L. C., Luningham, J., Fung Ip, H., Hagenbeek, F., Roetman, P., Gatej, R., Lamers, A., Nivard, M. G., van Dongen, J., Lu, Y., Middeldorp, C., van Beijsterveldt, T., Vermeiren, R., Hankemeijer, T. & 16 others, Kluft, C., Medland, S., Lundström, S., Rose, R., Pulkkinen, L., Vuoksimaa, E., Korhonen, T., Martin, N. G., Lubke, G., Finkenauer, C., Fanos, V., Tiemeier, H., Lichtenstein, P., Plomin, R., Kaprio, J. & Boomsma, D. I., Sep 2018, In : European Child and Adolescent Psychiatry. 27, 9, p. 1105-1121 17 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Risk factors for parental psychopathology: a study in families with children or adolescents with psychopathology

Wesseldijk, L. W., Dieleman, G. C., van Steensel, F. J. A., Bartels, M., Hudziak, J. J., Lindauer, R. J. L., Bögels, S. M. & Middeldorp, C. M., Dec 2018, In : European Child and Adolescent Psychiatry. 27, 12, p. 1575-1584 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2019

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Sullivan, P., 11 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies

Doering, S., Lichtenstein, P., Gillberg, C., Boomsma, D. I., Van Beijsterveldt, T. C. E. M., Ligthart, L., Willemsen, G., De Geus, E., Middeldorp, C. M., Bartels, M., Kuja-Halkola, R. & Lundström, S., 14 Nov 2019, In : BMC Psychiatry. 19, 1, p. 1-11 11 p., 363.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee, P. H., Anttila, V., Won, H., Feng, Y., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., Derks, E. M., op Landt Slof, M. C. T., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., W J H Penninx, B., Cath, D. C. & 11 others, Denys, D., Santangelo, S., Scharf, J. M., Stein, M. B., Thornton, L. M., Walters, J. T. R., Wray, N. R., Geschwind, D. H., Neale, B. M., Kendler, K. S. & Smoller, J. W., 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11 26 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Posthuma, D., 1 Nov 2019, In : Biological Psychiatry. 88, 2, p. 169-184

Research output: Contribution to JournalArticleAcademicpeer-review

2018

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, 22 Jun 2018, In : Science. 360, 6395, p. 1-15 15 p., eaap8757.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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2013

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Smoller, J. W., Ripke, S., Lee, P. H., Neale, B., Nurnberger, J. I., Santangelo, S., Sullivan, P. F., Perlis, R. H., Purcell, S. M., Fanous, A., Neale, M. C., Rietschel, M., Schulze, T. G., Thapar, A., Anney, R., Buitelaar, J. K., Farone, S. V., Hoogendijk, W. J. G., Levinson, D. F., Lesch, K. P. & 291 others, Riley, B., Schachar, R., Sonuga-Barke, E. J., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Arking, D., Asherson, P., Azevedo, M. H., Backlund, L., Badner, J. A., Banaschewski, T., Barchas, J. D., Barnes, M. R., Bass, N., Bauer, M. C. R., Bellivier, F., Bergen, S. E., Berrettini, W., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Buccola, N. G., Bunner, W. E., Burmeister, M., Buxbaum, J. D., Byerley, W. F., Sian, C., Cantor, R. M., Chakravarti, A., Chambert, K., Chicon, S., Cloniger, C. R., Collier, D. A., Cook, E., Coon, H., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Curtis, D., Czamara, D., Daly, M., Datta, S., Day, R., de Geus, E. J. C., Degenhardt, F., Devlin, B., Srdjan, D., Doyle, A. E., Duan, J., Dudbridge, F., Edenberg, H. J., Elkin, A., Etain, B., Farmer, A. E., Ferreira, M. A. R., Ferrier, I. N., Flickinger, M., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Friedl, M., Frisén, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Gross, M., Grozeva, D., Guan, W., Gurling, H., Gustafsson, O., Hakonarson, H., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hottenga, J. J., Hultman, C. M., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, L., Jones, I., Jung-Ying, T., Kahler, A., Kandaswamy, R., Keller, M. C., Kelsoe, J., Kennedy, J. L., Kenny, E., Kim, Y., Kirov, G. K., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krasucki, R., Kuntsi, J., Phoenix, K., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Lencz, T., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D., Liu, C., Lohoff, F. W., Loo, S. K., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Magnusson, P., Mahon, P. B., Maier, W., Malhotra, A. K., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S., McGhee, K. A., McGough, J. J., McGrath, P. J., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McClean, A. W., McMahon, F. J., McQuillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Middeldorp, C. M., Middleton, L., Vihra, M., Mitchell, P. B., Montgomery, G. W., Moran, J., Morken, G., Morris, D. W., Moskvina, V., Mowry, B. J., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Myers, R. M., Nelson, S. F., Nievergelt, C. M., Nikolovq, I., Nimgaonkar, V. L., Nolen, W. A., Nöthen, M. M., Nwulia, E. A., Nyholt, DR., O'Donovan, M. C., O'Dushlaine, C., Oades, R. D., Olincy, A., Olsen, L., Ophoff, R. A., Osby, U., Óskarsson, H., Owen, M. J., Palotie, A., Pato, M. T., Pato, C. N., Penninx, B. W. J. H., Pergadia, M. L., Petursson, H., Pickard, B. S., Pimm, J., Piven, J., Porgeirsson, P., Posthuma, D., Potash, J. B., Propping, J., Puri, V., Quested, D., Quinn, E. M., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Rice, J., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Schofield, P. R., Schork, N. J., Schumacher, J., Schwarz, M. M., Scolnick, E., Scott, L. J., Shi, J., Shillling, P. D., Shyn, S. I., Sigurdsson, E., Silverman, J. M., Sklar, P., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E., St Clair, D., State, M., Stefansson, K., Stefansson, H., Steffans, M., Steinberg, S., Steinhausen, H. C., Strauss, J., Strohmaier, J., Stroup, T. S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J., Grootheest, G., Vieland, V., Vincent, J. B., Visscher, P. M., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Willemsen, G., Williamson, R., Witt, S. H., Wray, N. R., Wright, A., Xu, W., Young, A. H., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S. & Kendler, K. S., 2013, In : Lancet. 381, 9875, p. 1371-1379

Research output: Contribution to JournalArticleAcademicpeer-review

2014

Waarom hebben we moeite met vernieuwing en verandering?

Vink, J. M. & Middeldorp, C. M., 1 Apr 2014, In : UP - clientenblad Lister.

Research output: Contribution to JournalArticlePopular

Agenda for future research. Psychiatric perpective.

van Dyck, R., van Balkom, A. J. L. M., van den Heuvel, O. & Middeldorp, C. M., 2014, The Wiley Handbook of Anxiety Disorders. Volume II: Clinical assessment and treatment.. Emmelkamp, P. M. G. & Ehring, T. (eds.). Chichester: Wiley, p. 1369-1381

Research output: Chapter in Book / Report / Conference proceedingChapterAcademic

2010

Genome-wide association study of suicide attempts in mood disorder patients

Perlis, R. H., Huang, J., Purcell, S., Fava, M., Rush, A. J., Sullivan, P. F., Hamilton, S. P., McMahon, S., Schulze, T., Potash, J. B., Zandi, P. P., Willour, V. L., Penninx, B. W. J. H., Boomsma, D. I., Vogelzangs, N., Middeldorp, C. M., Rietschel, M., Nöthen, M. M., Cichon, S., Gurling, H. & 6 others, Bass, N., McQuillin, A., Hamshere, M. L., Craddock, N., Sklar, P. & Smoller, J. W., 2010, In : American Journal of Psychiatry. 167, 12, p. 1499-1507

Research output: Contribution to JournalArticleAcademicpeer-review

2018

The value of polygenic analyses in psychiatry

Middeldorp, C. M. & Wray, N. R., Feb 2018, In : World Psychiatry. 17, 1, p. 26-28 3 p.

Research output: Contribution to JournalEditorialAcademicpeer-review

2013

Serotonin Transporter Gene: Will Epigenetics Prove Less Depressing Than Genetics?

de Geus, E. J. C. & Middeldorp, C. M., 2013, In : Psychosomatic Medicine. 75, 6, p. 520-522

Research output: Contribution to JournalArticleAcademicpeer-review

2012

Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms

Lubke, G. H., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Boomsma, D. I., 2012, In : Biological Psychiatry. 72, 8, p. 707-709

Research output: Contribution to JournalArticleAcademicpeer-review

2014

The Amsterdam Sexual Abuse Case (ASAC)-study in day care centers: longitudinal effects of sexual abuse on infants and very young children and their parents, and the consequences of the persistence of abusive images on the internet

Lindauer, R. J. L., Brilleslijper-Kater, S. N., Diehle, J., Verlinden, E., Teeuw, A. H., Middeldorp, C. M., Tuinebreijer, W., Bosschaart, T. F., van Duin, E. & Verhoeff, A., 2014, In : BMC Psychiatry. 14, p. 295 12 p., 295.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2017
Open Access