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Author

  • C.M. Middeldorp
2010

An Association Between Epac-1 Gene Variants and Anxiety and Depression in Two Independent Samples

Middeldorp, C. M., Vink, J. M., Hettema, J. M., de Geus, E. J. C., Kendler, K., Willemsen, G., Neale, M. C., Boomsma, D. I. & Chen, X., 2010, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 153B, 1, p. 214-219

Research output: Contribution to JournalArticleAcademicpeer-review

Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

Middeldorp, C. M., Slof-Op 't Landt, M. C. T., Medland, S. E., van Beijsterveldt, C. E. M., Bartels, M., Willemsen, G., Hottenga, J. J., de Geus, E. J. C., Suchiman, H. E. D., Dolan, C. V., Neale, M. C., Slagboom, P. E. & Boomsma, D. I., 2010, In : Genes, Brain and Behavior. 9, 6, p. 808-816

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Childhood and Adolescent Anxiety and Depression: Beyond Heritability

Franic, S., Middeldorp, C. M., Dolan, C. V., Ligthart, L. & Boomsma, D. I., 2010, In : Journal of the American Academy of Child and Adolescent Psychiatry. 49, 8, p. 820-829

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association study of suicide attempts in mood disorder patients

Perlis, R. H., Huang, J., Purcell, S., Fava, M., Rush, A. J., Sullivan, P. F., Hamilton, S. P., McMahon, S., Schulze, T., Potash, J. B., Zandi, P. P., Willour, V. L., Penninx, B. W. J. H., Boomsma, D. I., Vogelzangs, N., Middeldorp, C. M., Rietschel, M., Nöthen, M. M., Cichon, S., Gurling, H. & 6 others, Bass, N., McQuillin, A., Hamshere, M. L., Craddock, N., Sklar, P. & Smoller, J. W., 2010, In : American Journal of Psychiatry. 167, 12, p. 1499-1507

Research output: Contribution to JournalArticleAcademicpeer-review

Association study in eating disorders: TPH2 associates with anorexia nervosa and self induced vomiting

Slof-Op 't Landt, M. C. T., Meulenbelt, I., Bartels, M., Suchiman, E., Middeldorp, C. M., Houwing-Duistermaat, J. J., van Trier, J., Onkenhout, E. J., Vink, J. M., van Beijsterveldt, C. E. M., Brandys, M. K., Sanders, N., Zipfel, S., Herzog, W., Herpertz-Dahlmann, B., Klampfl, K., Fleischhaker, C., Zeeck, A., Zwaan, M., Herpertz, S. & 9 others, Ehrlich, S., van Elburg, A. A., Adan, R. A. H., Scherag, S., Hinney, A., Hebebrand, J., Boomsma, D. I., van Furth, E. F. & Slagboom, P. E., 2011, In : Genes, Brain and Behavior. 10, 2, p. 236-243

Research output: Contribution to JournalArticleAcademicpeer-review

Birth weight in a large series of triplets

Ponsen-Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M., Vink, J. M., Haak, M. C. & Boomsma, D. I., 2011, In : BMC Pediatrics. 11, 24.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: A genetic analysis of comorbidity

Distel, M. A., Carlier, A., Middeldorp, C. M., Derom, C. A., Lubke, G. H. & Boomsma, D. I., 2011, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156, 7, p. 817-825

Research output: Contribution to JournalArticleAcademicpeer-review

De invloed van genen en omgeving op de ontwikkeling van angststoornissen

Middeldorp, C. M. & Cath, D. C., 2011, Handboek angststoornissen. van Balkom, A. J. L. M., Oosterbaan, D., Visser, S. & van Vliet, I. M. (eds.). Utrecht: De Tijdstroom, p. 287-302 15 p.

Research output: Chapter in Book / Report / Conference proceedingChapterAcademic

Evidence for a causal association of low birth weight and attention problems

Groen-Blokhuis, M. M., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2011, In : Journal of the American Academy of Child and Adolescent Psychiatry. 50, 12, p. 1247-1254

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

Demirkan, A., Penninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlinden, A. G., Hottenga, J. J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. & 1 others, Middeldorp, C. M., 2011, In : Molecular Psychiatry. 16, 7, p. 773-783

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide complex trait analysis (gcta) for complex traits including major depressive disorder and smoking

Boomsma, D. I., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Lubke, G. H., 2011.

Research output: Contribution to ConferencePosterOther research output

Influence of Candidate Genes on Attention Problems in Children: A Longitudinal Study

van Beijsterveldt, C. E. M., Middeldorp, C. M., Slof-Op 't Landt, M. C. T., Bartels, M., Hottenga, J. J., Suchiman, H. E. D., Slagboom, P. E. & Boomsma, D. I., 2011, In : Behavior Genetics. 41, 1, p. 155-164

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Life events and borderline personality features: the influence of gene–environment interaction and gene–environment correlation

Distel, M. A., Middeldorp, C. M., Trull, T. J., Derom, C. A., Willemsen, G. & Boomsma, D. I., 2011, In : Psychological Medicine. 41, 4, p. 849-860

Research output: Contribution to JournalArticleAcademicpeer-review

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

Middeldorp, C. M., de Moor, M. H. M., McGrath, L. M., Gordon, S. D., Blackwood, D. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J. C., Nyholt, DR., Tanaka, T., Esko, T., Madden, P. A. F., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S. & 41 others, Spinhoven, P., Hartman, C. A., Ripke, S., Sullivan, P. F., Realo, A., Allik, J., Heath, A. C., Pergadia, M. L., Agrawal, A., Lin, P., Grucza, R. A., Widen, E., Cousminer, D. L., Eriksson, J. G., Palotie, A., Barnett, J. H., Lee, P. H., Luciano, M., Tenesa, A., Davies, G., Lopez, L. M., Hansell, N. K., Medland, S. E., Ferrucci, L., Schlessinger, D., Montgomery, GW., Wright, M. J., Aulchenko, Y. S., Janssens, A. C. J. W., Oostra, B. A., Metspalu, A., Abecasis, G. R., Deary, I. J., Räikkönen, K., Bierut, L. J., Martin, N. G., Wray, N. R., van Duijn, C. M., Smoller, J. W., Penninx, B. W. J. H. & Boomsma, D. I., 2011, In : Translational Psychiatry. 1, e50.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

The Impact of Environmental Experiences on Symptoms of Anxiety and Depression Across the Life Span

Kendler, K. S., Eaves, L. J., Loken, E. K., Pedersen, N. L., Middeldorp, C. M., Reynolds, C., Boomsma, D. I., Lichtenstein, P., Silberg, J. & Gardner, C. O., 2011, In : Psychological Science. 22, 10, p. 1343-1352

Research output: Contribution to JournalArticleAcademicpeer-review

2012

Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data

Brandys, M. K., Slof-Op 't Landt, M. C. T., van Elburg, A. A., Ophoff, R. A., Verduijn, W., Meulenbelt, I., Middeldorp, C. M., Boomsma, D. I., van Furth, E. F., Slagboom, P. E., Kas, M. J. H. & Adan, R. A. H., 2012, In : Psychiatric Genetics. 22, 3, p. 130-136

Research output: Contribution to JournalArticleAcademicpeer-review

Common variants at 12q15 and 12q24 are associated with infant head circumference

Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Boomsma, D. I., Hakonarson, H., Smith, G. D., Heinrich, J., Jarvelin, M-R. & Jaddoe, V. W. V., 2012, In : Nature Genetics. 44, 5, p. 532-538

Research output: Contribution to JournalArticleAcademicpeer-review

Common variants at 6q22 and 17q21 are associated with intracranial volume

Arfan Ikram, M., Fornage, M., Smith, A. V., Seshadri, S., Schmidt, R., Debette, S., Vrooman, H. A., Sigurdsson, S., Ropele, S., Taal, H. R., Mook-Kanamori, D. O., Coker, L. H., Longstreth, J. W. T., Niessen, W. J., DeStefano, A. L., Beiser, A., Zijdenbos, A. P., Struchalin, M., Jack, C. R., Rivadeneira, F. & 43 others, Uitterlinden, A. G., Knopman, D. S., Hartikainen, A-L., Pennell, C. E., Thiering, E., Steegers, E. A. P., Hakonarson, H., Heinrich, J., Palmer, L. J., Jarvelin, M-R., McCarthy, M. I., Grant, S. F. A., St Pourcain, B., Timpson, N. J., Smith, G. D., Sovio, U., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., Nalls, M. A., Au, R., Hofman, A., Gudnason, H., van der Lugt, A., Harris, T. B., Meeks, W. M., Vernooij, M. W., van Buchem, M. A., Catellier, D., Jaddoe, V. W. V., Gudnason, V., Windham, B. G., Wolf, P. A., van Duijn, C. M., Mosley, T. H., Schmidt, H., Launer, L. J., Breteler, M. M. B. & DeCarli, C. S., 2012, In : Nature Genetics. 44, 5, p. 539-544

Research output: Contribution to JournalArticleAcademicpeer-review

Effects of Chorionicity and Zygosity on Triplet Birth Weight

Ponsen-Lamb, D. J., Vink, J. M., Middeldorp, C. M., van Beijsterveldt, C. E. M., Haak, M., Overbeek, L. I. H. & Boomsma, D. I., 2012, In : Twin Research and Human Genetics. 15, 2, p. 149-157

Research output: Contribution to JournalArticleAcademicpeer-review

Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms

Lubke, G. H., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Boomsma, D. I., 2012, In : Biological Psychiatry. 72, 8, p. 707-709

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

Wray, N. R., Pergadia, M. L., Blackwood, D. H., Penninx, B. W. J. H., Gordon, S. D., Nyholt, DR., Ripke, S., MacIntyre, D. J., McGhee, K. A., Maclean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., de Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., van den Oord, E. J. C. G., Liu, J. Z. & 12 others, Macgregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Madden, P. A. F. & Sullivan, P. F., 2012, In : Molecular Psychiatry. 17, 1, p. 36-48

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-Wide Association Uncovers Shared Genetic Effects Among Personality Traits and Mood States

Luciano, M., Huffman, J. E., Arias-Vasquez, A., Vinkhuyzen, A. A. E., Middeldorp, C. M., Giegling, I., Payton, A., Davies, G. E., Zgaga, L., Janzing, J. G., Ke, X. Y., Galesloot, T., Hartmann, A. M., Ollier, W., Tenesa, A., Hayward, C., Verhagen, M., Montgomery, G. W., Hottenga, J. J., Konte, B. & 24 others, Starr, J. M., Vitart, V., Vos, P. E., Madden, P. A. F., Willemsen, G., Konnerth, H., Horan, M. A., Porteous, D. J., Campbell, H., Vermeulen, S. H., Heath, A. C., Wright, A., Polasek, O., Kovacevic, S. B., Hastie, N., Franke, B., Boomsma, D. I., Martin, N. G., Rujescu, D., Wilson, J. F., Buitelaar, J., Pendleton, N., Rudan, I. & Deary, I. J., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 6, p. 684-695

Research output: Contribution to JournalArticleAcademicpeer-review

Maternal prenatal smoking and offspring emotional problems: No moderating effect of maternal or child 5-HTTLPR genotype

Geels, L. M., Groen-Blokhuis, M. M., van Beijsterveldt, C. E. M., Vink, J. M., Middeldorp, C. M., Bartels, M., Nelson, K. A., Huizenga, P. E., Davies, G. E. & Boomsma, D. I., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 8, p. 1009-1012

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

Webb, B. T., Guo, A. Y., Maher, B. S., Zhao, Z., van den Oord, E. J., Kendler, K. S., Riley, B. P., Gillespie, N. A., Prescott, C. A., Middeldorp, C. M., Willemsen, G., de Geus, E. J. C., Hottenga, J. J., Boomsma, D. I., Slagboom, P. E., Wray, N. R., Montgomery, G. W., Martin, N. G., Wright, M. J., Heath, A. C. & 15 others, Madden, P. A. F., Gelernter, J., Knowles, J. A., Hamilton, S. P., Weissman, M. M., Fyer, A. J., Huezo-Diaz, P., McGuffin, P., Farmer, A., Craig, I. W., Lewis, C., Sham, P., Crowe, R. R., Flint, J. & Hettema, J. M., 2012, In : European Journal of Human Genetics. 20, 10, p. 1078-1084

Research output: Contribution to JournalArticleAcademicpeer-review

Sex Differences in Genetic Architecture of Complex Phenotypes?

Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M., van Dongen, J., van Beek, J. H. D. A., Distel, M. A., de Moor, M. H. M., Smit, D. J. A., Minica, C. C., Ligthart, L., Geels, L. M., Abdellaoui, A., Middeldorp, C. M., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Boomsma, D. I., 2012, In : PLoS ONE. 7, 12, e47371.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
2013

A mega-analysis of genome-wide association studies for major depressive disorder

Ripke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Byrne, E. M., Blackwood, D. H., Boomsma, D. I., Cichon, S., Heath, A. C., Holsboer, F., Lucae, S., Madden, P. A., Martin, N. G., McGuffin, P., Muglia, P., Noethen, M. M., Penninx, B. W. J. H., Pergadia, M. L. & 96 others, Potash, J. B., Rietschel, M., Lin, D., Müller-Myhsok, B., Shi, J., Steinberg, S., Grabe, H. J., Lichtenstein, P., Magnusson, P., Perlis, R. H., Preisig, M., Smoller, J. W., Stefansson, K., Uher, R., Kutalik, Z., Tansey, K. E., Teumer, A., Viktorin, A., Barnes, M. R., Bettecken, T., Binder, E. B., Breuer, R., Castro, V. M., Churchill, S. E., Coryell, W. H., Craddock, N., Craig, I. W., Czamara, D., de Geus, E. J. C., Degenhardt, F., Farmer, A. E., Fava, M., Frank, J., Gainer, V. S., Gallagher, P. J., Gordon, S. D., Goryachev, S., Gross, M., Guipponi, M., Henders, A. K., Herms, S., Hickie, I. B., Hoefels, S., Hoogendijk, W. J. G., Hottenga, J. J., Iosifescu, D. V., Ising, M., Jones, I., Jones, L., Jung-Ying, T., Knowles, J. A., Kohane, I. S., Kohli, M. A., Korszun, A., Landen, M., Lawson, W. B., Lewis, G., MacIntyre, D. J., Maier, W., Mattheisen, M., McGrath, P. J., McIntosh, A., McLean, A., Middeldorp, C. M., Middleton, L., Montgomery, G. M., Murphy, S. N., Nauck, M., Nolen, W. A., Nyholt, DR., O'Donovan, M., Oskarsson, H., Pedersen, N., Scheftner, W. A., Schulz, A., Schulze, T. G., Shyn, S. I., Sigurdsson, E., Slager, S. L., Smit, J. H., Stefansson, H., Steffens, M., Thorgeirsson, T. E., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J., Grootheest, G., Völzke, H., Weilburg, J. B., Willemsen, G., Zitman, F. G., Neale, B., Daly, M., Levinson, D. F. & Sullivan, P. F., 2013, In : Molecular Psychiatry. 18, 4, p. 497-511

Research output: Contribution to JournalArticleAcademicpeer-review

Angst en depressie van de kindertijd tot in de volwassenheid

Middeldorp, C. M., 2013.

Research output: Contribution to ConferencePosterOther research output

A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems

Groen-Blokhuis, M. M., Franic, S., van Beijsterveldt, C. E. M., de Geus, E. J. C., Bartels, M., Davies, G. E., Ehli, E. A., Xiao, X., Scheet, P., Althoff, R. R., Hudziak, J. J., Middeldorp, C. M. & Boomsma, D. I., 2013, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 162, 5, p. 457-465

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 350 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Buccola, N. G., Buitelaar, J. K., Bunney, W. E., Buxbaum, J. D., Byerley, W. F., Byrne, E. M., Caesar, S., Cahn, W., Cantor, R. M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Cloninger, C. R., Collier, D. A., Cook, E. H., Coon, H., Corman, B., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Crosbie, J., Cuccaro, M. L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., de Geus, E. J. C., Degenhardt, F., Djurovic, S., Donohoe, G., Doyle, A. E., Duan, J., Dudbridge, F., Duketis, E., Ebstein, R. P., Edenberg, H. J., Elia, J., Ennis, S., Etain, B., Fanous, A., Farmer, A. E., Ferrier, I. N., Flickinger, M., Fombonne, E., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Freitag, C., Friedl, M., Frisén, L., Gallagher, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Geschwind, D. H., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grice, D. E., Gross, M., Grozeva, D., Guan, W., Gurling, H., de Haan, L., Haines, J. L., Hakonarson, H., Hallmayer, J., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hoogendijk, W. J. G., Hottenga, J. J., Hultman, C. M., Hus, V., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, I., Jones, L., Tzeng, J. Y., Kähler, A. K., Kahn, R. S., Kandaswamy, R., Keller, M. C., Kennedy, J. L., Kenny, E., Kent, L., Kim, Y., Kirov, G. K., Klauck, S. M., Klei, L., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krabbendam, L., Krasucki, R., Kuntsi, J., Kwan, P., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Ledbetter, D. H., Lee, P. H., Lencz, T., Lesch, K. P., Levinson, D. F., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Liu, C., Lohoff, F. W., Loo, S. K., Lord, C., Lowe, J. K., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Maestrini, E., Magnusson, P. K. E., Mahon, P. B., Maier, W., Malhotra, A. K., Mane, S. M., Martin, C. L., Martin, N. G., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S. A., McGhee, K. A., McGough, J. J., McGrath, P. J., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McLean, A. W., McMahon, F. J., McMahon, W. M., McQuillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Meyer, J., Middeldorp, C. M., Middleton, L., Milanova, V., Miranda, A., Monaco, A. P., Montgomery, G. W., Moran, J. L., Moreno-De Luca, D., Morken, G., Morris, D. W., Morrow, E. M., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Murtha, M., Myers, R. M., Myin-Germeys, I., Neale, M. C., Nelson, S. F., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V. L., Nolen, W. A., Nöthen, M. M., Nurnberger, J. I., Nwulia, E. A., Nyholt, DR., O'Dushlaine, C., Oades, R. D., Olincy, A., Oliveira, G., Olsen, L., Ophoff, R. A., Osby, U., Owen, M. J., Palotie, A., Parr, J. R., Paterson, A. D., Pato, C. N., Pato, M. T., Penninx, B. W. J. H., Pergadia, M. L., Pericak-Vance, M. A., Pickard, B. S., Pimm, J., Piven, J., Posthuma, D., Potash, J. B., Poustka, F., Propping, P., Puri, V., Quested, D., Quinn, E. M., Ramos-Quiroga, J. A., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Ribasés, M., Rice, J. P., Rietschel, M., Roeder, K., Roeyers, H., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Sanders, S. J., Santangelo, S., Sergeant, J. A., Schachar, R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Scherer, S. W., Schork, N. J., Schulze, T. G., Schumacher, J., Schwarz, M., Scolnick, E., Scott, L. J., Shi, J., Shilling, P. D., Shyn, S. I., Silverman, J. M., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E. J., St Clair, D., State, M., Steffens, M., Steinhausen, H. C., Strauss, J., Strohmaier, J., Stroup, T. S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Todorov, A. A., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J. C. G., Grootheest, G., van Os, J., Vicente, A., Vieland, V., Vincent, J. B., Visscher, P. M., Walsh, C. A., Wassink, T. H., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Wijsman, E. M., Willemsen, G., Williams, N., Willsey, A. J., Witt, S. H., Xu, W., Young, A. H., Yu, T. W., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S., Devlin, B., Kelsoe, J., Sklar, P., Daly, M. J., O'Donovan, M. C., Craddock, N., Sullivan, P. F., Smoller, J. W., Kendler, K. S. & Wray, N. R., 2013, In : Nature Genetics. 45, 9, p. 984-994

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetic Variation at the TPH2 Gene Influences Impulsivity in Addition to Eating Disorders

Slof-Op 't Landt, M. C. T., Bartels, M., Middeldorp, C. M., van Beijsterveldt, C. E. M., Slagboom, P. E., Boomsma, D. I., van Furth, E. F. & Meulenbelt, I., 2013, In : Behavior Genetics. 43, 1, p. 24-33

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth pubertal timing and childhood adiposity

Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., Groen-Blokhuis, M. M., Kreiner-Møller, E., Marinelli, M., Holst, C., Leinonen, J. T., Perry, J. R., Surakka, I., Pietilainen, O. P., Kettunen, J., Anttila, V. & 269 others, Kaakinen, M., Sovio, U., Pouta, A., Das, S., Lagou, V., Power, C., Prokopenko, I., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Palotie, A., Kajantie, E., Osmond, C., Lehtimäki, T., Viikari, J. S., Kähönen, M., Warrington, N. M., Lye, S. J., Palmer, L. J., Tiesler, C. M. T., Flexeder, C., Montgomery, G. W., Medland, S. E., Hofman, A., Hakonarson, H., Guxens, M., Bartels, M., Salomaa, V., Adair, L. S., Atalay, M., van Beijsterveldt, C. E. M., Bergen, N., Benke, K. S., Charoen, P., Coin, L., Cooper, C., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Feenstra, B., Frayling, T. M., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M. W., Goh, L. K., Hattersley, A. T., Haworth, C. M., Hadley, D., Hedebrand, J., Hinney, A., Hirschhorn, J. N., Hocher, B., Holloway, J. W., Hottenga, J. J., Horikoshi, M., Iñiguez, C., Järvelin, M. R., Kilpeläinen, T. O., Kirin, M., Kowgier, M., Lakka, H. M., Lakka, T. A., Lange, L. A., Lawlor, D. A., Lewin, A., Lindgren, C. M., Lindi, V., Maggi, R., Marsh, J., Melbye, M., Middeldorp, C. M., Millwood, I., Mohlke, K. L., Mook-Kanamori, D. O., Murray, J. C., Nivard, M. G., Nohr, E. A., Ntalla, I., Oken, E., Ong, K. K., O'Reilly, P. F., Panoutsopoulou, K., Pararajasingham, J., Pearson, E. R., Price, T. S., Rodriguez, A., Salem, R. M., Saw, S. M., Scherag, A., Sebert, S., Siitonen, N., Simell, O., Strachan, D. P., Sunyer, J., Teo, Y. Y., Uitterlinden, A. G., Valcárcel, B., White, S., Widén, E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zeggini, E., Elks, C. E., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Gudbjartsson, D. F., Esko, T., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K. E., Smith, E. N., Ulivi, S., Warrington, M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Coviello, A. D., d'Adamo, P., de Faire, U., de Geus, E. J. C., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hu, F. B., Illig, T., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., McArdle, W. L., Mooser, V., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Porcu, E., Rafnar, T., Rice, J. P., Rivadeneira, F., Rudan, I., Sala, C., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V., Shuldiner, A. R., Soranzo, N., Srinivasan, S. R., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D., Weedon, M. N., Wichmann, H. E., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Murray, A., Murabito, J. M., Kaprio, J., Sørensen, T. I. A., Ballester, F., Bisgaard, H., Boomsma, D. I., Koppelman, G. H., Grant, S. F., Jaddoe, V. W., Martin, N. G., Heinrich, J., Raitakari, O. T., Eriksson, J. G., Smith, G. D., Hyppönen, E., McCarthy, M. I. & Ripatti, S., 2013, In : Human Molecular Genetics. 22, 13, p. 2735-2747

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Smoller, J. W., Ripke, S., Lee, P. H., Neale, B., Nurnberger, J. I., Santangelo, S., Sullivan, P. F., Perlis, R. H., Purcell, S. M., Fanous, A., Neale, M. C., Rietschel, M., Schulze, T. G., Thapar, A., Anney, R., Buitelaar, J. K., Farone, S. V., Hoogendijk, W. J. G., Levinson, D. F., Lesch, K. P. & 291 others, Riley, B., Schachar, R., Sonuga-Barke, E. J., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Arking, D., Asherson, P., Azevedo, M. H., Backlund, L., Badner, J. A., Banaschewski, T., Barchas, J. D., Barnes, M. R., Bass, N., Bauer, M. C. R., Bellivier, F., Bergen, S. E., Berrettini, W., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Buccola, N. G., Bunner, W. E., Burmeister, M., Buxbaum, J. D., Byerley, W. F., Sian, C., Cantor, R. M., Chakravarti, A., Chambert, K., Chicon, S., Cloniger, C. R., Collier, D. A., Cook, E., Coon, H., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Curtis, D., Czamara, D., Daly, M., Datta, S., Day, R., de Geus, E. J. C., Degenhardt, F., Devlin, B., Srdjan, D., Doyle, A. E., Duan, J., Dudbridge, F., Edenberg, H. J., Elkin, A., Etain, B., Farmer, A. E., Ferreira, M. A. R., Ferrier, I. N., Flickinger, M., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Friedl, M., Frisén, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Gross, M., Grozeva, D., Guan, W., Gurling, H., Gustafsson, O., Hakonarson, H., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hottenga, J. J., Hultman, C. M., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, L., Jones, I., Jung-Ying, T., Kahler, A., Kandaswamy, R., Keller, M. C., Kelsoe, J., Kennedy, J. L., Kenny, E., Kim, Y., Kirov, G. K., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krasucki, R., Kuntsi, J., Phoenix, K., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Lencz, T., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D., Liu, C., Lohoff, F. W., Loo, S. K., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Magnusson, P., Mahon, P. B., Maier, W., Malhotra, A. K., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S., McGhee, K. A., McGough, J. J., McGrath, P. J., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McClean, A. W., McMahon, F. J., McQuillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Middeldorp, C. M., Middleton, L., Vihra, M., Mitchell, P. B., Montgomery, G. W., Moran, J., Morken, G., Morris, D. W., Moskvina, V., Mowry, B. J., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Myers, R. M., Nelson, S. F., Nievergelt, C. M., Nikolovq, I., Nimgaonkar, V. L., Nolen, W. A., Nöthen, M. M., Nwulia, E. A., Nyholt, DR., O'Donovan, M. C., O'Dushlaine, C., Oades, R. D., Olincy, A., Olsen, L., Ophoff, R. A., Osby, U., Óskarsson, H., Owen, M. J., Palotie, A., Pato, M. T., Pato, C. N., Penninx, B. W. J. H., Pergadia, M. L., Petursson, H., Pickard, B. S., Pimm, J., Piven, J., Porgeirsson, P., Posthuma, D., Potash, J. B., Propping, J., Puri, V., Quested, D., Quinn, E. M., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Rice, J., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Schofield, P. R., Schork, N. J., Schumacher, J., Schwarz, M. M., Scolnick, E., Scott, L. J., Shi, J., Shillling, P. D., Shyn, S. I., Sigurdsson, E., Silverman, J. M., Sklar, P., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E., St Clair, D., State, M., Stefansson, K., Stefansson, H., Steffans, M., Steinberg, S., Steinhausen, H. C., Strauss, J., Strohmaier, J., Stroup, T. S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J., Grootheest, G., Vieland, V., Vincent, J. B., Visscher, P. M., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Willemsen, G., Williamson, R., Witt, S. H., Wray, N. R., Wright, A., Xu, W., Young, A. H., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S. & Kendler, K. S., 2013, In : Lancet. 381, 9875, p. 1371-1379

Research output: Contribution to JournalArticleAcademicpeer-review

Serotonin Transporter Gene: Will Epigenetics Prove Less Depressing Than Genetics?

de Geus, E. J. C. & Middeldorp, C. M., 2013, In : Psychosomatic Medicine. 75, 6, p. 520-522

Research output: Contribution to JournalArticleAcademicpeer-review

Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

Peyrot, W., Middeldorp, C. M., Jansen, R., Smit, J. H., de Geus, E. J. C., Hottenga, J. J., Willemsen, G., Vink, J. M., Virding, S., Barragan, I., Ingelman-Sundberg, M., Sim, S. C., Boomsma, D. I. & Penninx, B. W. J. H., 2013, In : Journal of Affective Disorders. 146, 1, p. 91-99

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The use of longitudinal data of childhood and adolescent internalizing problems in genetic studies

Middeldorp, C. M., 2013.

Research output: Contribution to ConferencePosterOther research output

The Val66Met polymorphism of the BDNF gene in anorexia nervosa: New data and a meta-analysis

Brandys, M. K., Kas, M. J. H., van Elburg, A. A., Ophoff, R. A., Slof-Op 't Landt, M. C. T., Middeldorp, C. M., Boomsma, D. I., van Furth, E. F., Slagboom, P. E. & Adan, R. A. H., 2013, In : World Journal of Biological Psychiatry. 14, 6, p. 441-451

Research output: Contribution to JournalArticleAcademicpeer-review

The Young Netherlands Twin Register (YNTR): Longitudinal Twin and Family Studies in Over 70,000 Children

van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Franic, S., Hudziak, J. J., Lamb, D. J., Huppertz, C., de Zeeuw, E. L., Nivard, M. G., Schutte, N. M., Swagerman, S. C., Glasner, T. J., van Fulpen, M. J., Brouwer, C. D., Stroet, T. M., Nowotny, D., Ehli, E. A., Davies, G. E., Scheet, P., Orlebeke, J. F., Kan, K. J. & 6 others, Smit, D. J. A., Dolan, C. V., Middeldorp, C. M., de Geus, E. J. C., Bartels, M. & Boomsma, D. I., 2013, In : Twin Research and Human Genetics. 16, 1, p. 252-267

Research output: Contribution to JournalArticleAcademicpeer-review

2015

Analysis of Behavioral and Emotional Problems in Children Highlights the Role of Genotype 9 Environment Interaction

Molenaar, D., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2015, In : Child Development. 86, 6, p. 1999-2016 18 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height

Fedko, I. O., Hottenga, J. J., Medina-Gomez, C., Pappa, I., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Rivadeneira, F., Tiemeier, H., Swertz, M. A., Middeldorp, C. M., Bartels, M. & Boomsma, D. I., 2015, In : Behavior Genetics. 45, 5, p. 514-528 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetica en psychische stoornissen op de kinderleeftijd: erfelijkheid en de zoektocht naar genen

Middeldorp, C. M., 2015, In : Tijdschrift voor Psychiatrie. 57, 12, p. 876-880 5 p.

Research output: Contribution to JournalArticleProfessional

Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood

Nivard, M. G., Middeldorp, C. M., Dolan, C. V. & Boomsma, D. I., 2015, In : Twin Research and Human Genetics. 18, 6, p. 746-754 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K. V., Balsevich, G., Schmidt, M. V., Karbalai, N., Czamara, D., Altmann, A., Trümbach, D., Wurst, W., Mehta, D., Uhr, M., Klengel, T., Erhardt, A., Carey, C. E., Drabant Conley, E., Boomsma, D. I. & 10 others, Penninx, B. W. J. H., de Geus, E. J. C., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Smit, J. H., Ruepp, A., Müller-Myhsok, B., Hariri, A. & Binder, E. B., 2015, In : Neuron. 86, p. 1189-1202 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Maier, R., Moser, G., Chen, G. B., Ripke, S., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Coryell, W. H., Potash, J. B., Scheftner, W. A., Shi, J., Weissmann, M. M., Hultman, C. M., Landén, M., Levinson, D. F., Kendler, K. S., Smoller, J. W., Wray, N. R. & 1 others, Lee, S. H., 2015, In : American Journal of Human Genetics. 96, 2, p. 283-294 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bonnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 130 others, Kalb, B., Pino-Yanes, M., Xu, C., Carstensen, L., Groen-Blokhuis, M. M., Venturini, C., Pennell, C. E., Barton, S. J., Levin, A. M., Curjuric, I., Bustamante, M., Kreiner-Moller, E., Lockett, G. A., Bacelis, J., Bunyavanich, S., Myers, R. A., Matanovic, A., Kumar, A., Tung, J. Y., Hirota, T., Kubo, M., McArdle, W. L., Henderson, A. J., Kemp, J. P., Zheng, J., Smith, G. D., Rueschendorf, F., Bauerfeind, A., Lee-Kirsch, M. A., Arnold, A., Homuth, G., Schmidt, C. O., Mangold, E., Cichon, S., Keil, T., Rodriguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Foelster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L. L., Grarup, N., de Jongste, J. C., Rivadeneira, F., Hofman, A., Jaddoe, V. W. V., Pasmans, S. G. M. A., Elbert, N. J., Uitterlinden, A. G., Marks, G. B., Thompson, P. J., Matheson, M. C., Robertson, C. F., Ried, J. S., Li, J., Zuo, X. B., Zheng, X. D., Yin, X. Y., Sun, L. D., McAleer, M. A., O'Regan, G. M., Fahy, C. M. R., Campbell, L. E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D. S., Feenstra, B., Geller, F., Hottenga, J. J., Middeldorp, C. M., Hysi, P., Bataille, V., Spector, T., Tiesler, C. M. T., Thiering, E., Pahukasahasram, B., Yang, J. J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C. L., Myhre, R., Nystad, W., Custovic, A., Weiss, S. T., Meyers, D. A., Soederhaell, C., Melen, E., Ober, C., Raby, B. A., Simpson, A., Jacobsson, B., Holloway, J. W., Bisgaard, H., Sunyer, J., Probst-Hensch, N. M., Williams, L. K., Godfrey, K. M., Wang, C. A., Boomsma, D. I., Melbye, M., Koppelman, G. H., Jarvis, D., McLean, W. H. I., Irvine, A. D., Zhang, X. J., Hakonarson, H., Gieger, C., Burchard, E. G., Martin, N. G., Duijts, L., Linneberg, A., Jarvelin, M., Noethen, M. M., Lau, S., Huebner, N., Lee, Y., Tamari, M., Hinds, D. A., Glass, D., Brown, S. J., Heinrich, J., Evans, D. M. & Weidinger, S., 2015, In : Nature Genetics. 47, 12, p. 1449-1456

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