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  • C.M. Middeldorp
2012

Common variants at 12q15 and 12q24 are associated with infant head circumference

Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Boomsma, D. I., Hakonarson, H., Smith, G. D., Heinrich, J., Jarvelin, M-R. & Jaddoe, V. W. V., 2012, In : Nature Genetics. 44, 5, p. 532-538

Research output: Contribution to JournalArticleAcademicpeer-review

Common variants at 6q22 and 17q21 are associated with intracranial volume

Arfan Ikram, M., Fornage, M., Smith, A. V., Seshadri, S., Schmidt, R., Debette, S., Vrooman, H. A., Sigurdsson, S., Ropele, S., Taal, H. R., Mook-Kanamori, D. O., Coker, L. H., Longstreth, J. W. T., Niessen, W. J., DeStefano, A. L., Beiser, A., Zijdenbos, A. P., Struchalin, M., Jack, C. R., Rivadeneira, F. & 43 others, Uitterlinden, A. G., Knopman, D. S., Hartikainen, A-L., Pennell, C. E., Thiering, E., Steegers, E. A. P., Hakonarson, H., Heinrich, J., Palmer, L. J., Jarvelin, M-R., McCarthy, M. I., Grant, S. F. A., St Pourcain, B., Timpson, N. J., Smith, G. D., Sovio, U., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., Nalls, M. A., Au, R., Hofman, A., Gudnason, H., van der Lugt, A., Harris, T. B., Meeks, W. M., Vernooij, M. W., van Buchem, M. A., Catellier, D., Jaddoe, V. W. V., Gudnason, V., Windham, B. G., Wolf, P. A., van Duijn, C. M., Mosley, T. H., Schmidt, H., Launer, L. J., Breteler, M. M. B. & DeCarli, C. S., 2012, In : Nature Genetics. 44, 5, p. 539-544

Research output: Contribution to JournalArticleAcademicpeer-review

Effects of Chorionicity and Zygosity on Triplet Birth Weight

Ponsen-Lamb, D. J., Vink, J. M., Middeldorp, C. M., van Beijsterveldt, C. E. M., Haak, M., Overbeek, L. I. H. & Boomsma, D. I., 2012, In : Twin Research and Human Genetics. 15, 2, p. 149-157

Research output: Contribution to JournalArticleAcademicpeer-review

Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms

Lubke, G. H., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Boomsma, D. I., 2012, In : Biological Psychiatry. 72, 8, p. 707-709

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

Wray, N. R., Pergadia, M. L., Blackwood, D. H., Penninx, B. W. J. H., Gordon, S. D., Nyholt, DR., Ripke, S., MacIntyre, D. J., McGhee, K. A., Maclean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., de Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., van den Oord, E. J. C. G., Liu, J. Z. & 12 others, Macgregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Madden, P. A. F. & Sullivan, P. F., 2012, In : Molecular Psychiatry. 17, 1, p. 36-48

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-Wide Association Uncovers Shared Genetic Effects Among Personality Traits and Mood States

Luciano, M., Huffman, J. E., Arias-Vasquez, A., Vinkhuyzen, A. A. E., Middeldorp, C. M., Giegling, I., Payton, A., Davies, G. E., Zgaga, L., Janzing, J. G., Ke, X. Y., Galesloot, T., Hartmann, A. M., Ollier, W., Tenesa, A., Hayward, C., Verhagen, M., Montgomery, G. W., Hottenga, J. J., Konte, B. & 24 others, Starr, J. M., Vitart, V., Vos, P. E., Madden, P. A. F., Willemsen, G., Konnerth, H., Horan, M. A., Porteous, D. J., Campbell, H., Vermeulen, S. H., Heath, A. C., Wright, A., Polasek, O., Kovacevic, S. B., Hastie, N., Franke, B., Boomsma, D. I., Martin, N. G., Rujescu, D., Wilson, J. F., Buitelaar, J., Pendleton, N., Rudan, I. & Deary, I. J., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 6, p. 684-695

Research output: Contribution to JournalArticleAcademicpeer-review

Maternal prenatal smoking and offspring emotional problems: No moderating effect of maternal or child 5-HTTLPR genotype

Geels, L. M., Groen-Blokhuis, M. M., van Beijsterveldt, C. E. M., Vink, J. M., Middeldorp, C. M., Bartels, M., Nelson, K. A., Huizenga, P. E., Davies, G. E. & Boomsma, D. I., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 8, p. 1009-1012

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

Webb, B. T., Guo, A. Y., Maher, B. S., Zhao, Z., van den Oord, E. J., Kendler, K. S., Riley, B. P., Gillespie, N. A., Prescott, C. A., Middeldorp, C. M., Willemsen, G., de Geus, E. J. C., Hottenga, J. J., Boomsma, D. I., Slagboom, P. E., Wray, N. R., Montgomery, G. W., Martin, N. G., Wright, M. J., Heath, A. C. & 15 others, Madden, P. A. F., Gelernter, J., Knowles, J. A., Hamilton, S. P., Weissman, M. M., Fyer, A. J., Huezo-Diaz, P., McGuffin, P., Farmer, A., Craig, I. W., Lewis, C., Sham, P., Crowe, R. R., Flint, J. & Hettema, J. M., 2012, In : European Journal of Human Genetics. 20, 10, p. 1078-1084

Research output: Contribution to JournalArticleAcademicpeer-review

Sex Differences in Genetic Architecture of Complex Phenotypes?

Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M., van Dongen, J., van Beek, J. H. D. A., Distel, M. A., de Moor, M. H. M., Smit, D. J. A., Minica, C. C., Ligthart, L., Geels, L. M., Abdellaoui, A., Middeldorp, C. M., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Boomsma, D. I., 2012, In : PLoS ONE. 7, 12, e47371.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Association study in eating disorders: TPH2 associates with anorexia nervosa and self induced vomiting

Slof-Op 't Landt, M. C. T., Meulenbelt, I., Bartels, M., Suchiman, E., Middeldorp, C. M., Houwing-Duistermaat, J. J., van Trier, J., Onkenhout, E. J., Vink, J. M., van Beijsterveldt, C. E. M., Brandys, M. K., Sanders, N., Zipfel, S., Herzog, W., Herpertz-Dahlmann, B., Klampfl, K., Fleischhaker, C., Zeeck, A., Zwaan, M., Herpertz, S. & 9 others, Ehrlich, S., van Elburg, A. A., Adan, R. A. H., Scherag, S., Hinney, A., Hebebrand, J., Boomsma, D. I., van Furth, E. F. & Slagboom, P. E., 2011, In : Genes, Brain and Behavior. 10, 2, p. 236-243

Research output: Contribution to JournalArticleAcademicpeer-review

Birth weight in a large series of triplets

Ponsen-Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M., Vink, J. M., Haak, M. C. & Boomsma, D. I., 2011, In : BMC Pediatrics. 11, 24.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: A genetic analysis of comorbidity

Distel, M. A., Carlier, A., Middeldorp, C. M., Derom, C. A., Lubke, G. H. & Boomsma, D. I., 2011, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156, 7, p. 817-825

Research output: Contribution to JournalArticleAcademicpeer-review

De invloed van genen en omgeving op de ontwikkeling van angststoornissen

Middeldorp, C. M. & Cath, D. C., 2011, Handboek angststoornissen. van Balkom, A. J. L. M., Oosterbaan, D., Visser, S. & van Vliet, I. M. (eds.). Utrecht: De Tijdstroom, p. 287-302 15 p.

Research output: Chapter in Book / Report / Conference proceedingChapterAcademic

Evidence for a causal association of low birth weight and attention problems

Groen-Blokhuis, M. M., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2011, In : Journal of the American Academy of Child and Adolescent Psychiatry. 50, 12, p. 1247-1254

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

Demirkan, A., Penninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlinden, A. G., Hottenga, J. J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. & 1 others, Middeldorp, C. M., 2011, In : Molecular Psychiatry. 16, 7, p. 773-783

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide complex trait analysis (gcta) for complex traits including major depressive disorder and smoking

Boomsma, D. I., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Lubke, G. H., 2011.

Research output: Contribution to ConferencePosterOther research output

Influence of Candidate Genes on Attention Problems in Children: A Longitudinal Study

van Beijsterveldt, C. E. M., Middeldorp, C. M., Slof-Op 't Landt, M. C. T., Bartels, M., Hottenga, J. J., Suchiman, H. E. D., Slagboom, P. E. & Boomsma, D. I., 2011, In : Behavior Genetics. 41, 1, p. 155-164

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Life events and borderline personality features: the influence of gene–environment interaction and gene–environment correlation

Distel, M. A., Middeldorp, C. M., Trull, T. J., Derom, C. A., Willemsen, G. & Boomsma, D. I., 2011, In : Psychological Medicine. 41, 4, p. 849-860

Research output: Contribution to JournalArticleAcademicpeer-review

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

Middeldorp, C. M., de Moor, M. H. M., McGrath, L. M., Gordon, S. D., Blackwood, D. H., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J. C., Nyholt, DR., Tanaka, T., Esko, T., Madden, P. A. F., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S. & 41 others, Spinhoven, P., Hartman, C. A., Ripke, S., Sullivan, P. F., Realo, A., Allik, J., Heath, A. C., Pergadia, M. L., Agrawal, A., Lin, P., Grucza, R. A., Widen, E., Cousminer, D. L., Eriksson, J. G., Palotie, A., Barnett, J. H., Lee, P. H., Luciano, M., Tenesa, A., Davies, G., Lopez, L. M., Hansell, N. K., Medland, S. E., Ferrucci, L., Schlessinger, D., Montgomery, GW., Wright, M. J., Aulchenko, Y. S., Janssens, A. C. J. W., Oostra, B. A., Metspalu, A., Abecasis, G. R., Deary, I. J., Räikkönen, K., Bierut, L. J., Martin, N. G., Wray, N. R., van Duijn, C. M., Smoller, J. W., Penninx, B. W. J. H. & Boomsma, D. I., 2011, In : Translational Psychiatry. 1, e50.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

The Impact of Environmental Experiences on Symptoms of Anxiety and Depression Across the Life Span

Kendler, K. S., Eaves, L. J., Loken, E. K., Pedersen, N. L., Middeldorp, C. M., Reynolds, C., Boomsma, D. I., Lichtenstein, P., Silberg, J. & Gardner, C. O., 2011, In : Psychological Science. 22, 10, p. 1343-1352

Research output: Contribution to JournalArticleAcademicpeer-review

2010

An Association Between Epac-1 Gene Variants and Anxiety and Depression in Two Independent Samples

Middeldorp, C. M., Vink, J. M., Hettema, J. M., de Geus, E. J. C., Kendler, K., Willemsen, G., Neale, M. C., Boomsma, D. I. & Chen, X., 2010, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 153B, 1, p. 214-219

Research output: Contribution to JournalArticleAcademicpeer-review

Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

Middeldorp, C. M., Slof-Op 't Landt, M. C. T., Medland, S. E., van Beijsterveldt, C. E. M., Bartels, M., Willemsen, G., Hottenga, J. J., de Geus, E. J. C., Suchiman, H. E. D., Dolan, C. V., Neale, M. C., Slagboom, P. E. & Boomsma, D. I., 2010, In : Genes, Brain and Behavior. 9, 6, p. 808-816

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Childhood and Adolescent Anxiety and Depression: Beyond Heritability

Franic, S., Middeldorp, C. M., Dolan, C. V., Ligthart, L. & Boomsma, D. I., 2010, In : Journal of the American Academy of Child and Adolescent Psychiatry. 49, 8, p. 820-829

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association study of suicide attempts in mood disorder patients

Perlis, R. H., Huang, J., Purcell, S., Fava, M., Rush, A. J., Sullivan, P. F., Hamilton, S. P., McMahon, S., Schulze, T., Potash, J. B., Zandi, P. P., Willour, V. L., Penninx, B. W. J. H., Boomsma, D. I., Vogelzangs, N., Middeldorp, C. M., Rietschel, M., Nöthen, M. M., Cichon, S., Gurling, H. & 6 others, Bass, N., McQuillin, A., Hamshere, M. L., Craddock, N., Sklar, P. & Smoller, J. W., 2010, In : American Journal of Psychiatry. 167, 12, p. 1499-1507

Research output: Contribution to JournalArticleAcademicpeer-review