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  • R. Haselberg

Affinity profiling of monoclonal antibody and antibody-drug-conjugate preparations by coupled liquid chromatography-surface plasmon resonance biosensing

Lakayan, D., Haselberg, R., Gahoual, R., Somsen, G. W. & Kool, J., 1 Dec 2018, In : Analytical and Bioanalytical Chemistry. 410, 30, p. 7837-7848 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

A Novel Platinum(II)-Based Bifunctional ADC Linker Benchmarked Using Zr-89-Desferal and Auristatin F-Conjugated Trastuzumab

Sijbrandi, N. J., Merkul, E., Muns, J. A., Waalboer, D. C. J., Adamzek, K., Bolijn, M., Montserrat, V., Somsen, G. W., Haselberg, R., Steverink, P. J. G. M., Houthoff, H-J. & van Dongen, G. A. M. S., 15 Jan 2017, In : Cancer Research. 77, 2, p. 257-267 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Capillary Electrophoresis: Trends and Recent Advances

Voeten, R. L. C., Ventouri, I. K., Haselberg, R. & Somsen, G. W., 6 Feb 2018, In : Analytical Chemistry. 90, 3, p. 1464-1481 18 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access

Capillary electrophoresis-mass spectrometry using noncovalently coated capillaries for the analysis of biopharmaceuticals

Haselberg, R., Brinks, V., de Jong, G. J., Somsen, G. W. & Hawe, A., Apr 2011, In : Analytical and Bioanalytical Chemistry. 400, 1, p. 295-303

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Capillary zone electrophoresis-mass spectrometry of intact proteins

Domínguez-Vega, E., Haselberg, R. & Somsen, G. W., 2016, Capillary Electrophoresis of Proteins and Peptides: Methods and Protocols. Tran, N. T. & Taverna, M. (eds.). Humana Press Inc, p. 25-41 17 p. (Methods in Molecular Biology; vol. 1466).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

CE-MS for the analysis of intact proteins 2010-2012

Haselberg, R., de Jong, G. J. & Somsen, G. W., 2013, In : Electrophoresis. 34, p. 99-112

Research output: Contribution to JournalArticleAcademicpeer-review

Characterization of drug-lysozyme conjugates by sheathless capillary electrophoresis-time-of-flight mass spectrometry

Haselberg, R., Harmsen, S., Dolman, M. E. M., de Jong, G. J., Kok, R. J. & Somsen, G. W., 18 Jul 2011, In : Analytica Chimica Acta. 698, 1-2, p. 77-83

Research output: Contribution to JournalArticleAcademicpeer-review

Development of a capillary zone electrophoresis method to quantify E. coli L-asparaginase and its acidic variants

Yao, H., Vandenbossche, J., Sänger-van de Griend, C. E., Janssens, Y., Fernández, C. S., Xu, X., Wynendaele, E., Somsen, G. W., Haselberg, R. & De Spiegeleer, B., 15 May 2018, In : Talanta. 182, p. 83-91 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Development of a surface plasmon resonance sensor for coupling to capillary electrophoresis allowing affinity assessment of protein mixture components

Domínguez-Vega, E., Haselberg, R., Iperen, D. V., Kool, J., Somsen, G. W. & de Jong, G. J., 1 Jan 2018, In : Sensors and Actuators B-Chemical. 254, p. 1040-1047 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Developments in interfacing designs for CE–MS: towards enabling tools for proteomics and metabolomics

Lindenburg, P. W., Haselberg, R., Rozing, G. & Ramautar, R., 2015, In : Chromatographia. 78, p. 367-377

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Direct electrokinetic injection of inorganic cations from whole fruits and vegetables for electrophoresis analysis.

Kasloom, U., Guijt, R. M., Boyce, M. C., Townsend, A. T., Haselberg, R. & Breadmore, M. C., 2016, In : Journal of Chromatography A. 1428, p. 346-351

Research output: Contribution to JournalArticleAcademicpeer-review

Evaluation of capillary electrophoresis-mass spectrometry for the analysis of the conformational heterogeneity of intact proteins using beta2-microglobulin as model compound.

Bertoletti, L., Schappler, J., Colombo, R., Rudaz, S., Haselberg, R., Dominguez Vega, E., Raimondi, S., Somsen, G. W. & De Lorenzi, E., 2016, In : Analytica Chimica Acta. 945, p. 102-109

Research output: Contribution to JournalArticleAcademicpeer-review

Evanescent-wave cavity enhanced spectroscopy as a tool in label-free biosensing

van der Sneppen, L., Ritchie, G. R. S., Hancock, G., Ariese, F., Gooijer, C., Ubachs, W., Haselberg, R., Somsen, G. W. & De Jong, G. J., 2010, Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference: 2010 Laser Science to Photonic Applications, CLEO/QELS 2010. 5499550

Research output: Chapter in Book / Report / Conference proceedingConference contributionAcademicpeer-review

Fully compatible and ultra-sensitive micellar electrokinetic chromatography-tandem mass spectrometry using sheathless porous-tip interfacing

Moreno-González, D., Haselberg, R., Gámiz-Gracia, L., García-Campaña, A. M., de Jong, G. J. & Somsen, G. W., 2017, (Accepted/In press) In : Journal of Chromatography A. 1524, p. 283-289 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Heterogeneity assessment of antibody-derived therapeutics at the intact and middle-up level by low-flow sheathless capillary electrophoresis-mass spectrometry

Haselberg, R., De Vijlder, T., Heukers, R., Smit, M. J., Romijn, E. P., Somsen, G. W. & Domínguez-Vega, E., 31 Dec 2018, In : Analytica Chimica Acta. 1044, p. 181-190 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

High-resolution glycoform profiling of intact therapeutic proteins by hydrophilic interaction chromatography-mass spectrometry

Domínguez-Vega, E., Tengattini, S., Peintner, C., van Angeren, J., Temporini, C., Haselberg, R., Massolini, G. & Somsen, G. W., Jul 2018, In : Talanta. 184, July, p. 375-381 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Intact protein analysis by capillary electrophoresis - mass spectrometry.

Haselberg, R. & Somsen, G. W., 2016, Capillary electrophoresis - Mass Spectrometry: Principles and Applications.. De Jong, G. J. (ed.). Wiley, p. 159-192

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Interlaboratory study to evaluate the robustness of capillary electrophoresis-mass spectrometry for peptide mapping

Wenz, C., Barbas, C., Lõpez-Gonzálvez, Á., Garcia, A., Benavente, F., Sanz-Nebot, V., Blanc, T., Freckleton, G., Britz-McKibbin, P., Shanmuganathan, M., de l'Escaille, F., Far, J., Haselberg, R., Huang, S., Huhn, C., Pattky, M., Michels, D., Mou, S., Yang, F., Neusuess, C. & 4 others, Tromsdorf, N., Baidoo, E. E. K., Keasling, J. D. & Park, S. S., 1 Sep 2015, In : Journal of Separation Science. 38, 18, p. 3262-3270 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Low-flow sheathless capillary electrophoresis-mass spectrometry for sensitive glycoform profiling of intact pharmaceutical proteins

Haselberg, R., de Jong, G. J. & Somsen, G. W., 2013, In : Analytical Chemistry. 85, p. 2289-2296

Research output: Contribution to JournalArticleAcademicpeer-review

Mass spectrometry for glycosylation analysis of biopharmaceuticals

Dotz, V., Haselberg, R., Shubhakar, A., Kozak, R. P., Falck, D., Rombouts, Y., Reusch, D., Somsen, G. W., Fernandes, D. L. & Wuhrer, M., 2015, In : TrAC. Trends in Analytical Chemistry. 73, p. 1-9

Research output: Contribution to JournalArticleAcademicpeer-review

Online Affinity Assessment and Immunoaffinity Sample Pretreatment in Capillary Electrophoresis-Mass Spectrometry

Haselberg, R. & Somsen, G. W., 1 Jan 2013, Analyzing Biomolecular Interactions by Mass Spectrometry. Wiley & Blackwell, p. 271-298 28 p.

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Platinum(II) as Bifunctional Linker in Antibody-Drug Conjugate Formation: Coupling of a 4-Nitrobenzo-2-oxa-1,3-diazole Fluorophore to Trastuzumab as a Model

Waalboer, D. C. J., Muns, J. A., Sijbrandi, N. J., Schasfoort, R. B. M., Haselberg, R., Somsen, G. W., Houthoff, H. J. & van Dongen, G. A. M. S., 2015, In : ChemMedChem. 10, 5, p. 797-803

Research output: Contribution to JournalArticleAcademicpeer-review

Quality and barch-to-batch consistency of original and biosimilar epoetin products.

Andhyk Halim, L., Brinks, V., Jiskoot, W., Romeijn, S., Haselberg, R., Burns, C., Wadhwa, M. & Schellekens, H., 2016, In : Journal of Pharmaceutical Sciences. 105, p. 542-550

Research output: Contribution to JournalArticleAcademicpeer-review

Simultaneous Assessment of Protein Heterogeneity and Affinity by Capillary Electrophoresis-Mass Spectrometry

Domínguez-Vega, E., Haselberg, R., Somsen, G. W. & De Jong, G. J., 1 Sep 2015, In : Analytical Chemistry. 87, 17, p. 8781-8788 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Thickness and morphology of polyelectrolyte coatings on silica surfaces before and after protein exposure studied by atomic force microscopy

Haselberg, R., Flesch, F., Boerke, A. & Somsen, G. W., 2013, In : Analytica Chimica Acta. 779, p. 90-95

Research output: Contribution to JournalArticleAcademicpeer-review