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  • R. Haselberg
2018

Affinity profiling of monoclonal antibody and antibody-drug-conjugate preparations by coupled liquid chromatography-surface plasmon resonance biosensing

Lakayan, D., Haselberg, R., Gahoual, R., Somsen, G. W. & Kool, J., 1 Dec 2018, In : Analytical and Bioanalytical Chemistry. 410, 30, p. 7837-7848 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Capillary Electrophoresis: Trends and Recent Advances

Voeten, R. L. C., Ventouri, I. K., Haselberg, R. & Somsen, G. W., 6 Feb 2018, In : Analytical Chemistry. 90, 3, p. 1464-1481 18 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access

Development of a capillary zone electrophoresis method to quantify E. coli L-asparaginase and its acidic variants

Yao, H., Vandenbossche, J., Sänger-van de Griend, C. E., Janssens, Y., Fernández, C. S., Xu, X., Wynendaele, E., Somsen, G. W., Haselberg, R. & De Spiegeleer, B., 15 May 2018, In : Talanta. 182, p. 83-91 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Development of a surface plasmon resonance sensor for coupling to capillary electrophoresis allowing affinity assessment of protein mixture components

Domínguez-Vega, E., Haselberg, R., Iperen, D. V., Kool, J., Somsen, G. W. & de Jong, G. J., 1 Jan 2018, In : Sensors and Actuators B-Chemical. 254, p. 1040-1047 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Heterogeneity assessment of antibody-derived therapeutics at the intact and middle-up level by low-flow sheathless capillary electrophoresis-mass spectrometry

Haselberg, R., De Vijlder, T., Heukers, R., Smit, M. J., Romijn, E. P., Somsen, G. W. & Domínguez-Vega, E., 31 Dec 2018, In : Analytica Chimica Acta. 1044, p. 181-190 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

High-resolution glycoform profiling of intact therapeutic proteins by hydrophilic interaction chromatography-mass spectrometry

Domínguez-Vega, E., Tengattini, S., Peintner, C., van Angeren, J., Temporini, C., Haselberg, R., Massolini, G. & Somsen, G. W., Jul 2018, In : Talanta. 184, July, p. 375-381 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2016

Capillary zone electrophoresis-mass spectrometry of intact proteins

Domínguez-Vega, E., Haselberg, R. & Somsen, G. W., 2016, Capillary Electrophoresis of Proteins and Peptides: Methods and Protocols. Tran, N. T. & Taverna, M. (eds.). Humana Press Inc, p. 25-41 17 p. (Methods in Molecular Biology; vol. 1466).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Direct electrokinetic injection of inorganic cations from whole fruits and vegetables for electrophoresis analysis.

Kasloom, U., Guijt, R. M., Boyce, M. C., Townsend, A. T., Haselberg, R. & Breadmore, M. C., 2016, In : Journal of Chromatography A. 1428, p. 346-351

Research output: Contribution to JournalArticleAcademicpeer-review

Evaluation of capillary electrophoresis-mass spectrometry for the analysis of the conformational heterogeneity of intact proteins using beta2-microglobulin as model compound.

Bertoletti, L., Schappler, J., Colombo, R., Rudaz, S., Haselberg, R., Dominguez Vega, E., Raimondi, S., Somsen, G. W. & De Lorenzi, E., 2016, In : Analytica Chimica Acta. 945, p. 102-109

Research output: Contribution to JournalArticleAcademicpeer-review

Intact protein analysis by capillary electrophoresis - mass spectrometry.

Haselberg, R. & Somsen, G. W., 2016, Capillary electrophoresis - Mass Spectrometry: Principles and Applications.. De Jong, G. J. (ed.). Wiley, p. 159-192

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Quality and barch-to-batch consistency of original and biosimilar epoetin products.

Andhyk Halim, L., Brinks, V., Jiskoot, W., Romeijn, S., Haselberg, R., Burns, C., Wadhwa, M. & Schellekens, H., 2016, In : Journal of Pharmaceutical Sciences. 105, p. 542-550

Research output: Contribution to JournalArticleAcademicpeer-review

2015

Developments in interfacing designs for CE–MS: towards enabling tools for proteomics and metabolomics

Lindenburg, P. W., Haselberg, R., Rozing, G. & Ramautar, R., 2015, In : Chromatographia. 78, p. 367-377

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Interlaboratory study to evaluate the robustness of capillary electrophoresis-mass spectrometry for peptide mapping

Wenz, C., Barbas, C., Lõpez-Gonzálvez, Á., Garcia, A., Benavente, F., Sanz-Nebot, V., Blanc, T., Freckleton, G., Britz-McKibbin, P., Shanmuganathan, M., de l'Escaille, F., Far, J., Haselberg, R., Huang, S., Huhn, C., Pattky, M., Michels, D., Mou, S., Yang, F., Neusuess, C. & 4 others, Tromsdorf, N., Baidoo, E. E. K., Keasling, J. D. & Park, S. S., 1 Sep 2015, In : Journal of Separation Science. 38, 18, p. 3262-3270 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Mass spectrometry for glycosylation analysis of biopharmaceuticals

Dotz, V., Haselberg, R., Shubhakar, A., Kozak, R. P., Falck, D., Rombouts, Y., Reusch, D., Somsen, G. W., Fernandes, D. L. & Wuhrer, M., 2015, In : TrAC. Trends in Analytical Chemistry. 73, p. 1-9

Research output: Contribution to JournalArticleAcademicpeer-review

Platinum(II) as Bifunctional Linker in Antibody-Drug Conjugate Formation: Coupling of a 4-Nitrobenzo-2-oxa-1,3-diazole Fluorophore to Trastuzumab as a Model

Waalboer, D. C. J., Muns, J. A., Sijbrandi, N. J., Schasfoort, R. B. M., Haselberg, R., Somsen, G. W., Houthoff, H. J. & van Dongen, G. A. M. S., 2015, In : ChemMedChem. 10, 5, p. 797-803

Research output: Contribution to JournalArticleAcademicpeer-review

Simultaneous Assessment of Protein Heterogeneity and Affinity by Capillary Electrophoresis-Mass Spectrometry

Domínguez-Vega, E., Haselberg, R., Somsen, G. W. & De Jong, G. J., 1 Sep 2015, In : Analytical Chemistry. 87, 17, p. 8781-8788 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2013

CE-MS for the analysis of intact proteins 2010-2012

Haselberg, R., de Jong, G. J. & Somsen, G. W., 2013, In : Electrophoresis. 34, p. 99-112

Research output: Contribution to JournalArticleAcademicpeer-review

Low-flow sheathless capillary electrophoresis-mass spectrometry for sensitive glycoform profiling of intact pharmaceutical proteins

Haselberg, R., de Jong, G. J. & Somsen, G. W., 2013, In : Analytical Chemistry. 85, p. 2289-2296

Research output: Contribution to JournalArticleAcademicpeer-review

Online Affinity Assessment and Immunoaffinity Sample Pretreatment in Capillary Electrophoresis-Mass Spectrometry

Haselberg, R. & Somsen, G. W., 1 Jan 2013, Analyzing Biomolecular Interactions by Mass Spectrometry. Wiley & Blackwell, p. 271-298 28 p.

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Thickness and morphology of polyelectrolyte coatings on silica surfaces before and after protein exposure studied by atomic force microscopy

Haselberg, R., Flesch, F., Boerke, A. & Somsen, G. W., 2013, In : Analytica Chimica Acta. 779, p. 90-95

Research output: Contribution to JournalArticleAcademicpeer-review

2011

Capillary electrophoresis-mass spectrometry using noncovalently coated capillaries for the analysis of biopharmaceuticals

Haselberg, R., Brinks, V., de Jong, G. J., Somsen, G. W. & Hawe, A., Apr 2011, In : Analytical and Bioanalytical Chemistry. 400, 1, p. 295-303

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Characterization of drug-lysozyme conjugates by sheathless capillary electrophoresis-time-of-flight mass spectrometry

Haselberg, R., Harmsen, S., Dolman, M. E. M., de Jong, G. J., Kok, R. J. & Somsen, G. W., 18 Jul 2011, In : Analytica Chimica Acta. 698, 1-2, p. 77-83

Research output: Contribution to JournalArticleAcademicpeer-review

2010

Evanescent-wave cavity enhanced spectroscopy as a tool in label-free biosensing

van der Sneppen, L., Ritchie, G. R. S., Hancock, G., Ariese, F., Gooijer, C., Ubachs, W., Haselberg, R., Somsen, G. W. & De Jong, G. J., 2010, Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference: 2010 Laser Science to Photonic Applications, CLEO/QELS 2010. 5499550

Research output: Chapter in Book / Report / Conference proceedingConference contributionAcademicpeer-review