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2013
Genetic and Environmental Stability in Attention Problems Across the Lifespan: Evidence From the Netherlands Twin Register
Kan, K. J., Dolan, C. V., Nivard, M. G., Middeldorp, C. M., van Beijsterveldt, C. E. M., Willemsen, G. & Boomsma, D. I., 2013, In : Journal of the American Academy of Child and Adolescent Psychiatry. 52, 1, p. 12-25Research output: Contribution to Journal › Article › Academic › peer-review
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2016
Multivariate and repeated measure GWAS of aggression phenotypes
Nivard, M. G., Middeldorp, C., Hottenga, J. J., Fedko, I., Ehli, E. A., Davies, G., van Beijsterveldt, C., Bartels, M. & Boomsma, D., Nov 2016, In : Behavior Genetics. 46, 6, p. 798-799Research output: Contribution to Journal › Meeting Abstract › Other research output
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Differences in maternal and paternal ratings of psychopathology and the genetic epidemiology in 12,000 7-year old twin pairs
Wesseldijk, L., Fedko, I., Bartels, M., Nivard, M. G., Hottenga, J-J., van Beijsterveldt, C., Boomsma, D. & Middeldorp, C., Nov 2016, In : Behavior Genetics. 46, 6, p. 813-814Research output: Contribution to Journal › Article › Academic › peer-review
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2014
Waarom hebben we moeite met vernieuwing en verandering?
Vink, J. M. & Middeldorp, C. M., 1 Apr 2014, In : UP - clientenblad Lister.Research output: Contribution to Journal › Article › Popular
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2013
The use of longitudinal data of childhood and adolescent internalizing problems in genetic studies
Middeldorp, C. M., 2013.Research output: Contribution to Conference › Poster › Other research output
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2017
EAGLE consortium. CAPICE: Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe
Middeldorp, C. M., 2017.Research output: Contribution to Conference › Poster › Academic
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2014
Interview
Middeldorp, C. M., 1 May 2014, In : Nieuwsbrief Fonds Psychische Gezondheid.Research output: Contribution to Journal › Article › Popular
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Agenda for future research. Psychiatric perpective.
van Dyck, R., van Balkom, A. J. L. M., van den Heuvel, O. & Middeldorp, C. M., 2014, The Wiley Handbook of Anxiety Disorders. Volume II: Clinical assessment and treatment.. Emmelkamp, P. M. G. & Ehring, T. (eds.). Chichester: Wiley, p. 1369-1381Research output: Chapter in Book / Report / Conference proceeding › Chapter › Academic
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2013
Angst en depressie van de kindertijd tot in de volwassenheid
Middeldorp, C. M., 2013.Research output: Contribution to Conference › Poster › Other research output
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2014
De meerwaarde van een familiepoli
Batelaan, N. M. & Middeldorp, C. M., 2014, In : PsychoPraktijk. 6, 3, p. 14-17 4 p.Research output: Contribution to Journal › Article › Professional
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2011
Genome-wide complex trait analysis (gcta) for complex traits including major depressive disorder and smoking
Boomsma, D. I., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Lubke, G. H., 2011.Research output: Contribution to Conference › Poster › Other research output
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2012
Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms
Lubke, G. H., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Boomsma, D. I., 2012, In : Biological Psychiatry. 72, 8, p. 707-709Research output: Contribution to Journal › Article › Academic › peer-review
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Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data
Brandys, M. K., Slof-Op 't Landt, M. C. T., van Elburg, A. A., Ophoff, R. A., Verduijn, W., Meulenbelt, I., Middeldorp, C. M., Boomsma, D. I., van Furth, E. F., Slagboom, P. E., Kas, M. J. H. & Adan, R. A. H., 2012, In : Psychiatric Genetics. 22, 3, p. 130-136Research output: Contribution to Journal › Article › Academic › peer-review
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Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes
Webb, B. T., Guo, A. Y., Maher, B. S., Zhao, Z., van den Oord, E. J., Kendler, K. S., Riley, B. P., Gillespie, N. A., Prescott, C. A., Middeldorp, C. M., Willemsen, G., de Geus, E. J. C., Hottenga, J. J., Boomsma, D. I., Slagboom, P. E., Wray, N. R., Montgomery, G. W., Martin, N. G., Wright, M. J., Heath, A. C. & 15 others, , 2012, In : European Journal of Human Genetics. 20, 10, p. 1078-1084Research output: Contribution to Journal › Article › Academic › peer-review
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2015
Spousal resemblance for smoking: Underlying mechanisms and effects of cohort and age
Treur, J. L., Vink, J. M., Boomsma, D. I. & Middeldorp, C. M., 2015, In : Drug and Alcohol Dependence. 153, p. 221-228 8 p.Research output: Contribution to Journal › Article › Academic › peer-review
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2014
Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders
Ligthart, L., Hottenga, J. J., Lewis, C. M., Farmer, A. E., Craig, I. W., Breen, G., Willemsen, G., Vink, J. M., Middeldorp, C. M., Byrne, E. M., Heath, A. C., Madden, P. A. F., Pergadia, M. L., Montgomery, G. W., Martin, N. G., Penninx, B. W. J. H., McGuffin, P., Boomsma, D. I. & Nyholt, DR., 2014, In : Human Genetics. 133, 2, p. 173-186 14 p.Research output: Contribution to Journal › Article › Academic › peer-review
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2015
Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder
Maier, R., Moser, G., Chen, G. B., Ripke, S., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Coryell, W. H., Potash, J. B., Scheftner, W. A., Shi, J., Weissmann, M. M., Hultman, C. M., Landén, M., Levinson, D. F., Kendler, K. S., Smoller, J. W., Wray, N. R. & 1 others, , 2015, In : American Journal of Human Genetics. 96, 2, p. 283-294 12 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2011
Evidence for a causal association of low birth weight and attention problems
Groen-Blokhuis, M. M., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2011, In : Journal of the American Academy of Child and Adolescent Psychiatry. 50, 12, p. 1247-1254Research output: Contribution to Journal › Article › Academic › peer-review
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2015
Analysis of Behavioral and Emotional Problems in Children Highlights the Role of Genotype 9 Environment Interaction
Molenaar, D., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2015, In : Child Development. 86, 6, p. 1999-2016 18 p.Research output: Contribution to Journal › Article › Academic › peer-review
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2016
Assessment and characterization of phenotypic heterogeneity of anxiety disorders across five large cohorts
Lee, M., Aggen, S. H., Otowa, T., Castelao, E., Preisig, M., Grabe, H. J., Hartman, C. A., Oldehinkel, A. J., Middeldorp, C. M., Tiemeier, H. & Hettema, J. M., Dec 2016, In : International Journal of Methods in Psychiatric Research. 25, 4, p. 255-266 12 p.Research output: Contribution to Journal › Article › Academic › peer-review
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2013
Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample
Peyrot, W., Middeldorp, C. M., Jansen, R., Smit, J. H., de Geus, E. J. C., Hottenga, J. J., Willemsen, G., Vink, J. M., Virding, S., Barragan, I., Ingelman-Sundberg, M., Sim, S. C., Boomsma, D. I. & Penninx, B. W. J. H., 2013, In : Journal of Affective Disorders. 146, 1, p. 91-99Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2014
Attention-Deficit/Hyperactivity Disorder Polygenic Risk Scores Predict Attention Problems in a Population-Based Sample of Children
Blokhuis, M. M., Middeldorp, C. M., Kan, K. J., Abdellaoui, A., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Scheet, P., Xiao, X., Hudziak, J. J., Hottenga, J. J., Neale, B. M. & Boomsma, D. I., 2014, In : Journal of the American Academy of Child and Adolescent Psychiatry. 53, 10, p. 1123-1129 7 p.Research output: Contribution to Journal › Article › Academic › peer-review
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The Amsterdam Sexual Abuse Case (ASAC)-study in day care centers: longitudinal effects of sexual abuse on infants and very young children and their parents, and the consequences of the persistence of abusive images on the internet
Lindauer, R. J. L., Brilleslijper-Kater, S. N., Diehle, J., Verlinden, E., Teeuw, A. H., Middeldorp, C. M., Tuinebreijer, W., Bosschaart, T. F., van Duin, E. & Verhoeff, A., 2014, In : BMC Psychiatry. 14, p. 295 12 p., 295.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2016
A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts
Middeldorp, C. M., Hammerschlag, A. R., Ouwens, K. G., Blokhuis, M. M., St. Pourcain, B., Greven, C. U., Pappa, I., Tiesler, C. M. T., Ang, W., Nolte, I. M., Vilor-Tejedor, N., Bacelis, J., Ebejer, J. L., Zhao, H., Davies, G. E., Ehli, E. A., Evans, D. M., Fedko, I. O., Guxens, M., Hottenga, J. J. & 31 others, , 2016, In : Journal of the American Academy of Child and Adolescent Psychiatry. 55, 10, p. 896-905 10.Research output: Contribution to Journal › Article › Academic › peer-review
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2011
Genetic risk profiles for depression and anxiety in adult and elderly cohorts
Demirkan, A., Penninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlinden, A. G., Hottenga, J. J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. & 1 others, , 2011, In : Molecular Psychiatry. 16, 7, p. 773-783Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2016
Evidence for Gender-Dependent Genotype by Environment Interaction in Adult Depression
Molenaar, D., Middeldorp, C. M., Willemsen, G., Ligthart, L., Nivard, M. G. & Boomsma, D. I., 2016, In : Behavior Genetics. 46, 1, p. 59-71Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2017
Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes
Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T. M., McGrath, J., Hickie, I. B., Hansell, N. K., Wright, M. J., Gillespie, N. A., Forstner, A. J., Schulze, T. G., Wüst, S., Nöthen, M. M., Baumgartner, M. R., Walker, B. R., Crawford, A. A. & 12 others, , 10 Nov 2017, In : Scientific Reports. 7, 1, p. 15351 15351.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
Hinney, A., Kesselmeier, M., Jall, S., Volckmar, A-L., Föcker, M., Antel, J., Heid, I. M., Winkler, T. W., Grant, S. F. A., Guo, Y., Bergen, A. W., Kaye, W., Berrettini, W., Hakonarson, H., Herpertz-Dahlmann, B., de Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Egberts, K. M. & 19 others, , Feb 2017, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.Research output: Contribution to Journal › Article › Academic › peer-review
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2011
Association study in eating disorders: TPH2 associates with anorexia nervosa and self induced vomiting
Slof-Op 't Landt, M. C. T., Meulenbelt, I., Bartels, M., Suchiman, E., Middeldorp, C. M., Houwing-Duistermaat, J. J., van Trier, J., Onkenhout, E. J., Vink, J. M., van Beijsterveldt, C. E. M., Brandys, M. K., Sanders, N., Zipfel, S., Herzog, W., Herpertz-Dahlmann, B., Klampfl, K., Fleischhaker, C., Zeeck, A., Zwaan, M., Herpertz, S. & 9 others, , 2011, In : Genes, Brain and Behavior. 10, 2, p. 236-243Research output: Contribution to Journal › Article › Academic › peer-review
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2016
Discovery of Biochemical Biomarkers for Aggression: A Role for Metabolomics in Psychiatry
Hagenbeek, F. A., Kluft, C., Hankemeier, T., Bartels, M., Draisma, H. H. M., Middeldorp, C. M., Berger, R., Noto, A., Lussu, M., Pool, R., Fanos, V. & Boomsma, D. I., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 5, p. 719-732Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Heritability of different aggression phenotypes in an Australian and a Dutch cohort
Conde, L. C., Martin, N. G., Hatemi, P., Boomsma, D., Middeldorp, C., Van Beijsterveldt, T., Bartels, M. & Medland, S. E., Nov 2016, In : Behavior Genetics. 46, 6, p. 776-777Research output: Contribution to Journal › Meeting Abstract › Other research output
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2017
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D. J., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Lopezz de Alda, M., Alliey-Rodriguez, N. & 31 others, , 20 Jun 2017, In : Translational Psychiatry. 7, 6, p. e1155Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2016
A powerful phenotype for gene-finding studies derived from trajectory analyses of symptoms of anxiety and depression between age seven and 18
Lubke, G. H., Miller, P. J., Verhulst, B., Bartels, M., van Beijsterveldt, C. E. M., Willemsen, G., Boomsma, D. I. & Middeldorp, C. M., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 7, p. 948-957Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2017
Heritability of Behavioral Problems in 7-Year Olds Based on Shared and Unique Aspects of Parental Views
Fedko, I. O., Wesseldijk, L. W., Nivard, M. G., Hottenga, J. J., van Beijsterveldt, C. E. M., Middeldorp, C. M., Bartels, M. & Boomsma, D. I., 1 Mar 2017, In : Behavior Genetics. 47, 2, p. 152-163 12 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2014
Child Care, Socio-economic Status and Problem Behavior: A Study of Gene–Environment Interaction in Young Dutch Twins
Middeldorp, C. M., Lamb, D. J., Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2014, In : Behavior Genetics. 44, 4, p. 314-325 12 p.Research output: Contribution to Journal › Article › Academic › peer-review
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2013
Genetic Variation at the TPH2 Gene Influences Impulsivity in Addition to Eating Disorders
Slof-Op 't Landt, M. C. T., Bartels, M., Middeldorp, C. M., van Beijsterveldt, C. E. M., Slagboom, P. E., Boomsma, D. I., van Furth, E. F. & Meulenbelt, I., 2013, In : Behavior Genetics. 43, 1, p. 24-33Research output: Contribution to Journal › Article › Academic › peer-review
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2015
Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height
Fedko, I. O., Hottenga, J. J., Medina-Gomez, C., Pappa, I., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Rivadeneira, F., Tiemeier, H., Swertz, M. A., Middeldorp, C. M., Bartels, M. & Boomsma, D. I., 2015, In : Behavior Genetics. 45, 5, p. 514-528 15 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2011
Adolescent Self-Report of Emotional and Behavioral Problems: Interactions of Genetic Factors with Sex and Age
Bartels, M., van der Aa, N., van Beijsterveldt, C. E. M., Middeldorp, C. M. & Boomsma, D. I., 2011, In : Journal of the Canadian Academy of Child and Adolescent Psychiatry. 20, 1, p. 35-52Research output: Contribution to Journal › Article › Academic › peer-review
Open AccessFile44 Downloads (Pure) -
2017
Genetic effects influencing risk for major depressive disorder in China and Europe
Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S. A., Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschøn, H. N., Byrne, E. M., Cichon, S., Clarke, T. K., Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F. & 77 others, , 28 Mar 2017, In : Translational Psychiatry. 7, 3, p. e1074 e1074.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2016
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Blokhuis, M. M., Horikoshi, M., Hottenga, J. J., Middeldorp, C. M., Uitterlinden, A. G., Plomin, R., Boomsma, D. I., Heinrich, J., Melbye, M., Rivadeneira, F. & 7 others, , 2016, In : Human Molecular Genetics. 25, 2, p. 389-403Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2017
Validity of LIDAS (LIfetime Depression Assessment Self-report): a self-report online assessment of lifetime major depressive disorder
Bot, M., Middeldorp, C. M., de Geus, E. J. C., Lau, H. M., Sinke, S. M., van Nieuwenhuizen, B., Smit, J. H., Boomsma, D. I. & Penninx, B. W. J. H., Jan 2017, In : Psychological Medicine. 47, 2, p. 279-289 11 p.Research output: Contribution to Journal › Article › Academic › peer-review
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Joint developmental trajectories of internalizing and externalizing disorders between childhood and adolescence
Nivard, M. G., Lubke, G. H., Dolan, C. V., Evans, D. M., St Pourcain, B., Munafò, M. R. & Middeldorp, C. M., 1 Aug 2017, In : Development and Psychopathology. 29, 3, p. 919-928 10 p.Research output: Contribution to Journal › Article › Academic › peer-review
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2015
Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood
Nivard, M. G., Middeldorp, C. M., Dolan, C. V. & Boomsma, D. I., 2015, In : Twin Research and Human Genetics. 18, 6, p. 746-754 9 p.Research output: Contribution to Journal › Article › Academic › peer-review
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2013
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
Smoller, J. W., Ripke, S., Lee, P. H., Neale, B., Nurnberger, J. I., Santangelo, S., Sullivan, P. F., Perlis, R. H., Purcell, S. M., Fanous, A., Neale, M. C., Rietschel, M., Schulze, T. G., Thapar, A., Anney, R., Buitelaar, J. K., Farone, S. V., Hoogendijk, W. J. G., Levinson, D. F., Lesch, K. P. & 291 others, , 2013, In : Lancet. 381, 9875, p. 1371-1379Research output: Contribution to Journal › Article › Academic › peer-review