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  Adolescent Self-Report of Emotional and Behavioral Problems: Interactions of Genetic Factors with Sex and Age

  Bartels, M., van der Aa, N., van Beijsterveldt, C. E. M., Middeldorp, C. M. & Boomsma, D. I., 2011, In : Journal of the Canadian Academy of Child and Adolescent Psychiatry. 20, 1, p. 35-52

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  File
  44 Downloads (Pure)

• A genome-wide approach to children's aggressive behavior: The EAGLE consortium

  Pappa, I., St Pourcain, B., Benke, K. S., Cavadino, A., Hakulinen, C., Nivard, M. G., Nolte, I. M., Tiesler, C. M. T., Bakermans-Kranenburg, M. J., Davies, G. E., Evans, D. M., Geoffroy, M. C., Grallert, H., Blokhuis, M. M., Hudziak, J. J., Kemp, J. P., Keltikangas-Järvinen, L., McMahon, G., Mileva-Seitz, V. R., Motazedi, E. & 23 others, Power, C., Raitakari, O. T., Ring, S. M., Rivadeneira, F., Rodriguez, A., Scheet, P., Seppälä, I., Snieder, H., Standl, M., Thiering, E., Timpson, N. J., Veenstra, R., Velders, F. P., Whitehouse, A. J. O., Davey Smith, G., Heinrich, J., Hypponen, E., Lehtimäki, T., Middeldorp, C. M., Oldehinkel, A. J., Pennell, C. E., Boomsma, D. I. & Tiemeier, H., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 5, p. 562-572

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Child Behavior
  • Genome
  • Single Nucleotide Polymorphism
  • Multifactorial Inheritance
  • Meta-Analysis

• A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts

  Middeldorp, C. M., Hammerschlag, A. R., Ouwens, K. G., Blokhuis, M. M., St. Pourcain, B., Greven, C. U., Pappa, I., Tiesler, C. M. T., Ang, W., Nolte, I. M., Vilor-Tejedor, N., Bacelis, J., Ebejer, J. L., Zhao, H., Davies, G. E., Ehli, E. A., Evans, D. M., Fedko, I. O., Guxens, M., Hottenga, J. J. & 31 others, Hudziak, J. J., Jugessur, A., Kemp, J. P., Krapohl, E., Martin, N. G., Murcia, M., Myhre, R., Ormel, J., Ring, S. M., Standl, M., Stergiakouli, E., Stoltenberg, C., Thiering, E., Timpson, N. J., Trzaskowski, M., van der Most, P. J., Wang, C., Nyholt, DR., Medland, S. E., Neale, B. M., Jacobsson, B., Sunyer, J., Hartman, C. A., Whitehouse, A. J. O., Pennell, C. E., Heinrich, J., Plomin, R., Davey Smith, G., Tiemeier, H., Posthuma, D. & Boomsma, D. I., 2016, In : Journal of the American Academy of Child and Adolescent Psychiatry. 55, 10, p. 896-905 10.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genome-Wide Association Study
  • Attention Deficit Disorder with Hyperactivity
  • Single Nucleotide Polymorphism
  • Meta-Analysis
  • Pediatrics

• A Genome-wide Association Meta-analysis of Preschool Internalizing Problems

  Benke, K. S., Nivard, M. G., Velders, F. P., Walters, R. K., Pappa, I., Scheet, P., Xiao, X., Ehli, E. A., Palmer, L. J., Whitehouse, A. J. O., Verhulst, F. C., Jaddoe, V. W., Rivadeneira, F., Blokhuis, M. M., van Beijsterveldt, C. E. M., Davies, G. E., Hudziak, J. J., Lubke, G. H., Boomsma, D. I., Pennell, C. E. & 2 others, Tiemeier, H. & Middeldorp, C. M., 2014, In : Journal of the American Academy of Child and Adolescent Psychiatry. 53, 6, p. 667-676 10 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Meta-Analysis
  • Genome
  • Psychiatry

• A mega-analysis of genome-wide association studies for major depressive disorder

  Ripke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Byrne, E. M., Blackwood, D. H., Boomsma, D. I., Cichon, S., Heath, A. C., Holsboer, F., Lucae, S., Madden, P. A., Martin, N. G., McGuffin, P., Muglia, P., Noethen, M. M., Penninx, B. W. J. H., Pergadia, M. L. & 96 others, Potash, J. B., Rietschel, M., Lin, D., Müller-Myhsok, B., Shi, J., Steinberg, S., Grabe, H. J., Lichtenstein, P., Magnusson, P., Perlis, R. H., Preisig, M., Smoller, J. W., Stefansson, K., Uher, R., Kutalik, Z., Tansey, K. E., Teumer, A., Viktorin, A., Barnes, M. R., Bettecken, T., Binder, E. B., Breuer, R., Castro, V. M., Churchill, S. E., Coryell, W. H., Craddock, N., Craig, I. W., Czamara, D., de Geus, E. J. C., Degenhardt, F., Farmer, A. E., Fava, M., Frank, J., Gainer, V. S., Gallagher, P. J., Gordon, S. D., Goryachev, S., Gross, M., Guipponi, M., Henders, A. K., Herms, S., Hickie, I. B., Hoefels, S., Hoogendijk, W. J. G., Hottenga, J. J., Iosifescu, D. V., Ising, M., Jones, I., Jones, L., Jung-Ying, T., Knowles, J. A., Kohane, I. S., Kohli, M. A., Korszun, A., Landen, M., Lawson, W. B., Lewis, G., MacIntyre, D. J., Maier, W., Mattheisen, M., McGrath, P. J., McIntosh, A., McLean, A., Middeldorp, C. M., Middleton, L., Montgomery, G. M., Murphy, S. N., Nauck, M., Nolen, W. A., Nyholt, DR., O'Donovan, M., Oskarsson, H., Pedersen, N., Scheftner, W. A., Schulz, A., Schulze, T. G., Shyn, S. I., Sigurdsson, E., Slager, S. L., Smit, J. H., Stefansson, H., Steffens, M., Thorgeirsson, T. E., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J., Grootheest, G., Völzke, H., Weilburg, J. B., Willemsen, G., Zitman, F. G., Neale, B., Daly, M., Levinson, D. F. & Sullivan, P. F., 2013, In : Molecular Psychiatry. 18, 4, p. 497-511

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genome-Wide Association Study
  • Major Depressive Disorder
  • Single Nucleotide Polymorphism
  • Bipolar Disorder
  • Genome

• Analysis of Behavioral and Emotional Problems in Children Highlights the Role of Genotype 9 Environment Interaction

  Molenaar, D., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2015, In : Child Development. 86, 6, p. 1999-2016 18 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Problem Behavior
  • Genotype
  • interaction
  • Child
  • Anxiety

• Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data

  Brandys, M. K., Slof-Op 't Landt, M. C. T., van Elburg, A. A., Ophoff, R. A., Verduijn, W., Meulenbelt, I., Middeldorp, C. M., Boomsma, D. I., van Furth, E. F., Slagboom, P. E., Kas, M. J. H. & Adan, R. A. H., 2012, In : Psychiatric Genetics. 22, 3, p. 130-136

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Anorexia Nervosa
  • Meta-Analysis
  • Odds Ratio
  • Genes
  • Guaiacol

• A powerful phenotype for gene-finding studies derived from trajectory analyses of symptoms of anxiety and depression between age seven and 18

  Lubke, G. H., Miller, P. J., Verhulst, B., Bartels, M., van Beijsterveldt, C. E. M., Willemsen, G., Boomsma, D. I. & Middeldorp, C. M., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 7, p. 948-957

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Twins
  • Anxiety
  • Depression
  • Phenotype
  • Genes

• A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems

  Groen-Blokhuis, M. M., Franic, S., van Beijsterveldt, C. E. M., de Geus, E. J. C., Bartels, M., Davies, G. E., Ehli, E. A., Xiao, X., Scheet, P., Althoff, R. R., Hudziak, J. J., Middeldorp, C. M. & Boomsma, D. I., 2013, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 162, 5, p. 457-465

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Breast Feeding
  • Cognition
  • Prospective Studies
  • Mothers
  • Education

• A recessive genetic model and runs of homozygosity in major depressive disorder

  Power, R. A., Keller, M. C., Ripke, S., Abdellaoui, A., Wray, N. R., Sullivan, P. F., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Middeldorp, C. M., Penninx, B. W. J. H., Willemsen, G. & Breen, G., 2014, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 165, 2, p. 157-166 10 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genetic Models
  • Genome-Wide Association Study
  • Major Depressive Disorder
  • Genome
  • Schizophrenia

• Assessment and characterization of phenotypic heterogeneity of anxiety disorders across five large cohorts

  Lee, M., Aggen, S. H., Otowa, T., Castelao, E., Preisig, M., Grabe, H. J., Hartman, C. A., Oldehinkel, A. J., Middeldorp, C. M., Tiemeier, H. & Hettema, J. M., Dec 2016, In : International Journal of Methods in Psychiatric Research. 25, 4, p. 255-266 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genome-Wide Association Study
  • Anxiety Disorders
  • Statistical Factor Analysis
  • Psychiatry
  • Phenotype

• Association study in eating disorders: TPH2 associates with anorexia nervosa and self induced vomiting

  Slof-Op 't Landt, M. C. T., Meulenbelt, I., Bartels, M., Suchiman, E., Middeldorp, C. M., Houwing-Duistermaat, J. J., van Trier, J., Onkenhout, E. J., Vink, J. M., van Beijsterveldt, C. E. M., Brandys, M. K., Sanders, N., Zipfel, S., Herzog, W., Herpertz-Dahlmann, B., Klampfl, K., Fleischhaker, C., Zeeck, A., Zwaan, M., Herpertz, S. & 9 others, Ehrlich, S., van Elburg, A. A., Adan, R. A. H., Scherag, S., Hinney, A., Hebebrand, J., Boomsma, D. I., van Furth, E. F. & Slagboom, P. E., 2011, In : Genes, Brain and Behavior. 10, 2, p. 236-243

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Tryptophan Hydroxylase
  • Anorexia Nervosa
  • Feeding and Eating Disorders
  • Vomiting
  • Odds Ratio

• Attention-Deficit/Hyperactivity Disorder Polygenic Risk Scores Predict Attention Problems in a Population-Based Sample of Children

  Blokhuis, M. M., Middeldorp, C. M., Kan, K. J., Abdellaoui, A., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Scheet, P., Xiao, X., Hudziak, J. J., Hottenga, J. J., Neale, B. M. & Boomsma, D. I., 2014, In : Journal of the American Academy of Child and Adolescent Psychiatry. 53, 10, p. 1123-1129 7 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Attention Deficit Disorder with Hyperactivity
  • Child
  • Population
  • Impulsive Behavior

• Birth weight in a large series of triplets

  Ponsen-Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M., Vink, J. M., Haak, M. C. & Boomsma, D. I., 2011, In : BMC Pediatrics. 11, 24.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  File

  • Birth Weight
  • Gestational Age
  • Mothers
  • Twins
  • Netherlands
  177 Downloads (Pure)

• Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: A genetic analysis of comorbidity

  Distel, M. A., Carlier, A., Middeldorp, C. M., Derom, C. A., Lubke, G. H. & Boomsma, D. I., 2011, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156, 7, p. 817-825

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Attention Deficit Disorder with Hyperactivity
  • Personality
  • Comorbidity
  • Borderline Personality Disorder
  • Personality Assessment

• Child Care, Socio-economic Status and Problem Behavior: A Study of Gene–Environment Interaction in Young Dutch Twins

  Middeldorp, C. M., Lamb, D. J., Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2014, In : Behavior Genetics. 44, 4, p. 314-325 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • child care
  • behavior problems
  • socioeconomic status
  • Economic Status
  • Child Care

• Common variants at 12q15 and 12q24 are associated with infant head circumference

  Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Boomsma, D. I., Hakonarson, H., Smith, G. D., Heinrich, J., Jarvelin, M-R. & Jaddoe, V. W. V., 2012, In : Nature Genetics. 44, 5, p. 532-538

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genome-Wide Association Study
  • Lead
  • Chromosomes
  • Meta-Analysis
  • Head

• Common variants at 6q22 and 17q21 are associated with intracranial volume

  Arfan Ikram, M., Fornage, M., Smith, A. V., Seshadri, S., Schmidt, R., Debette, S., Vrooman, H. A., Sigurdsson, S., Ropele, S., Taal, H. R., Mook-Kanamori, D. O., Coker, L. H., Longstreth, J. W. T., Niessen, W. J., DeStefano, A. L., Beiser, A., Zijdenbos, A. P., Struchalin, M., Jack, C. R., Rivadeneira, F. & 43 others, Uitterlinden, A. G., Knopman, D. S., Hartikainen, A-L., Pennell, C. E., Thiering, E., Steegers, E. A. P., Hakonarson, H., Heinrich, J., Palmer, L. J., Jarvelin, M-R., McCarthy, M. I., Grant, S. F. A., St Pourcain, B., Timpson, N. J., Smith, G. D., Sovio, U., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., Nalls, M. A., Au, R., Hofman, A., Gudnason, H., van der Lugt, A., Harris, T. B., Meeks, W. M., Vernooij, M. W., van Buchem, M. A., Catellier, D., Jaddoe, V. W. V., Gudnason, V., Windham, B. G., Wolf, P. A., van Duijn, C. M., Mosley, T. H., Schmidt, H., Launer, L. J., Breteler, M. M. B. & DeCarli, C. S., 2012, In : Nature Genetics. 44, 5, p. 539-544

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Brain
  • Genome-Wide Association Study
  • Independent Living
  • Biological Phenomena
  • Genome

• Crying Without a Cause and Being Easily Upset in Two-Year-Olds: Heritability and Predictive Power of Behavioral Problems

  Groen-Blokhuis, M. M., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2011, In : Twin Research and Human Genetics. 14, 5, p. 393-400

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Crying
  • Problem Behavior
  • Twins
  • Mothers
  • Personality

• De meerwaarde van een familiepoli

  Batelaan, N. M. & Middeldorp, C. M., 2014, In : PsychoPraktijk. 6, 3, p. 14-17 4 p.

  Research output: Contribution to Journal › Article › Professional

• Detection of gene-environment interaction in pedigree data using genome-wide genotypes

  Nivard, M. G., Middeldorp, C. M., Lubke, G. H., Hottenga, J. J., Abdellaoui, A., Boomsma, D. I. & Dolan, C. V., 2016, In : European Journal of Human Genetics. 24, 12, p. 1803-1809

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Gene-Environment Interaction
  • Pedigree
  • Single Nucleotide Polymorphism
  • Genotype
  • Genome

• Differences in maternal and paternal ratings of psychopathology and the genetic epidemiology in 12,000 7-year old twin pairs

  Wesseldijk, L., Fedko, I., Bartels, M., Nivard, M. G., Hottenga, J-J., van Beijsterveldt, C., Boomsma, D. & Middeldorp, C., Nov 2016, In : Behavior Genetics. 46, 6, p. 813-814

  Research output: Contribution to Journal › Article › Academic › peer-review

• Discovery of Biochemical Biomarkers for Aggression: A Role for Metabolomics in Psychiatry

  Hagenbeek, F. A., Kluft, C., Hankemeier, T., Bartels, M., Draisma, H. H. M., Middeldorp, C. M., Berger, R., Noto, A., Lussu, M., Pool, R., Fanos, V. & Boomsma, D. I., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 5, p. 719-732

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Metabolomics
  • Aggression
  • Psychiatry
  • Biomarkers
  • Lipoproteins

• Effects of Chorionicity and Zygosity on Triplet Birth Weight

  Ponsen-Lamb, D. J., Vink, J. M., Middeldorp, C. M., van Beijsterveldt, C. E. M., Haak, M., Overbeek, L. I. H. & Boomsma, D. I., 2012, In : Twin Research and Human Genetics. 15, 2, p. 149-157

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Birth Weight
  • Chorion
  • Low Birth Weight Infant
  • Twins
  • Surrogate Mothers

• Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms

  Lubke, G. H., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Boomsma, D. I., 2012, In : Biological Psychiatry. 72, 8, p. 707-709

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Major Depressive Disorder
  • Single Nucleotide Polymorphism
  • Twin Studies
  • Genome-Wide Association Study
  • Biological Psychiatry

• Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height

  Fedko, I. O., Hottenga, J. J., Medina-Gomez, C., Pappa, I., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Rivadeneira, F., Tiemeier, H., Swertz, M. A., Middeldorp, C. M., Bartels, M. & Boomsma, D. I., 2015, In : Behavior Genetics. 45, 5, p. 514-528 15 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • childhood
  • polymorphism
  • genetic relationships
  • single nucleotide polymorphism
  • heritability

• Evidence for a causal association of low birth weight and attention problems

  Groen-Blokhuis, M. M., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2011, In : Journal of the American Academy of Child and Adolescent Psychiatry. 50, 12, p. 1247-1254

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Low Birth Weight Infant
  • Birth Weight
  • Child
  • Twins
  • Growth

• Evidence for Gender-Dependent Genotype by Environment Interaction in Adult Depression

  Molenaar, D., Middeldorp, C. M., Willemsen, G., Ligthart, L., Nivard, M. G. & Boomsma, D. I., 2016, In : Behavior Genetics. 46, 1, p. 59-71

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • genotype
  • gender
  • Genotype
  • Depression
  • Twins

• Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

  Hinney, A., Kesselmeier, M., Jall, S., Volckmar, A-L., Föcker, M., Antel, J., Heid, I. M., Winkler, T. W., Grant, S. F. A., Guo, Y., Bergen, A. W., Kaye, W., Berrettini, W., Hakonarson, H., Herpertz-Dahlmann, B., de Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Egberts, K. M. & 19 others, Adan, R., Brandys, M., van Elburg, A., Boraska Perica, V., Franklin, C. S., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., GCAN, Hottenga, J. J., Willemsen, G., Boomsma, D. I., van Beijsterveldt, C. E. M., Middeldorp, C. M. & de Geus, E., Feb 2017, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genetic Loci
  • Anorexia Nervosa
  • Genome-Wide Association Study
  • Meta-Analysis
  • Single Nucleotide Polymorphism

• Further confirmation of the association between anxiety and CTNND2: replication in humans

  Nivard, M. G., Mbarek, H., Hottenga, J. J., Smit, J. H., Penninx, B. W. J. H., Middeldorp, C. M. & Boomsma, D. I., 2014, In : Genes, Brain and Behavior. 13, 2, p. 195-201 7 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Anxiety
  • Agoraphobia
  • Catenins
  • Social Phobia
  • Chromosome Mapping

• Gene–environment interaction in teacher-rated internalizing and externalizing problem behavior in 7- to 12-year-old twins

  Ponsen-Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2012, In : Journal of Child Psychology and Psychiatry. 53, 8, p. 818-825

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Twins
  • Problem Behavior
  • Gene-Environment Interaction
  • Adolescent Health
  • Latent Class Analysis

• Genetica en psychische stoornissen op de kinderleeftijd: erfelijkheid en de zoektocht naar genen

  Middeldorp, C. M., 2015, In : Tijdschrift voor Psychiatrie. 57, 12, p. 876-880 5 p.

  Research output: Contribution to Journal › Article › Professional

• Genetic and Environmental Stability in Attention Problems Across the Lifespan: Evidence From the Netherlands Twin Register

  Kan, K. J., Dolan, C. V., Nivard, M. G., Middeldorp, C. M., van Beijsterveldt, C. E. M., Willemsen, G. & Boomsma, D. I., 2013, In : Journal of the American Academy of Child and Adolescent Psychiatry. 52, 1, p. 12-25

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Twins
  • Netherlands
  • Longevity
  • Adolescent Psychiatry
  • Mothers

• Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood

  Nivard, M. G., Middeldorp, C. M., Dolan, C. V. & Boomsma, D. I., 2015, In : Twin Research and Human Genetics. 18, 6, p. 746-754 9 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Neuroticism
  • Genetic Models
  • Twins
  • Individuality
  • Longitudinal Studies

• Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

  Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K. V., Balsevich, G., Schmidt, M. V., Karbalai, N., Czamara, D., Altmann, A., Trümbach, D., Wurst, W., Mehta, D., Uhr, M., Klengel, T., Erhardt, A., Carey, C. E., Drabant Conley, E., Boomsma, D. I. & 10 others, Penninx, B. W. J. H., de Geus, E. J. C., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Smit, J. H., Ruepp, A., Müller-Myhsok, B., Hariri, A. & Binder, E. B., 2015, In : Neuron. 86, p. 1189-1202 15 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Transcriptome
  • Psychiatry
  • Glucocorticoid Receptors
  • Brain
  • Endophenotypes

• Genetic effects influencing risk for major depressive disorder in China and Europe

  Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S. A., Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschøn, H. N., Byrne, E. M., Cichon, S., Clarke, T. K., Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F. & 77 others, Dunn, E. C., Edwards, C. A., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D. S., Grabe, H. J., Hamilton, S. P., Hardiman, O., Hayward, C., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Hottenga, J-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J. A., Lang, M., Li, Q. S., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Martin, N. G., McGrath, P. J., McGuffin, P., McIntosh, A. M., Medland, S. E., Mehta, D., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D. R., Nöthen, M. M., Owen, M. J., Penninx, B. W. J. H., Pergadia, M. L., Perlis, R. H., Peyrot, W. J., Porteous, D. J., Potash, J. B., Rice, J. P., Rietschel, M., Riley, B. P., Rivera, M., Schoevers, R., Schulze, T. G., Shi, J., Shyn, S. I., Smit, J. H., Smoller, J. W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., van der Auwera, S. V., Grootheest, G., van Hemert, A. M., Völzke, H., Webb, B. T., Weissman, M. M., Wellmann, J., Willemsen, G., Witt, S. H., Levinson, D. F., Lewis, C. M., Wray, N. R., Flint, J., Sullivan, P. F. & Kendler, K. S., 28 Mar 2017, In : Translational Psychiatry. 7, 3, p. e1074 e1074.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Major Depressive Disorder
  • China
  • Single Nucleotide Polymorphism
  • Meta-Analysis
  • Twin Studies

• Genetic Overlap Between Schizophrenia and Developmental Psychopathology: Longitudinal and Multivariate Polygenic Risk Prediction of Common Psychiatric Traits During Development

  Nivard, M. G., Gage, S. H., Hottenga, J. J., van Beijsterveldt, C. E. M., Abdellaoui, A., Bartels, M., Baselmans, B. M. L., Ligthart, L., Pourcain, B. S., Boomsma, D. I., Munafò, M. R. & Middeldorp, C. M., 1 Nov 2017, In : Schizophrenia Bulletin. 43, 6, p. 1197-1207 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Psychopathology
  • Schizophrenia
  • Psychiatry
  • Attention Deficit and Disruptive Behavior Disorders
  • Conduct Disorder

• Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

  Lee, S. H., Ripke, S., Neale, B., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 350 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Buccola, N. G., Buitelaar, J. K., Bunney, W. E., Buxbaum, J. D., Byerley, W. F., Byrne, E. M., Caesar, S., Cahn, W., Cantor, R. M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Cloninger, C. R., Collier, D. A., Cook, E. H., Coon, H., Corman, B., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Crosbie, J., Cuccaro, M. L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., de Geus, E. J. C., Degenhardt, F., Djurovic, S., Donohoe, G., Doyle, A. E., Duan, J., Dudbridge, F., Duketis, E., Ebstein, R. P., Edenberg, H. J., Elia, J., Ennis, S., Etain, B., Fanous, A., Farmer, A. E., Ferrier, I. N., Flickinger, M., Fombonne, E., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Freitag, C., Friedl, M., Frisén, L., Gallagher, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Geschwind, D. H., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grice, D. E., Gross, M., Grozeva, D., Guan, W., Gurling, H., de Haan, L., Haines, J. L., Hakonarson, H., Hallmayer, J., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hoogendijk, W. J. G., Hottenga, J. J., Hultman, C. M., Hus, V., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, I., Jones, L., Tzeng, J. Y., Kähler, A. K., Kahn, R. S., Kandaswamy, R., Keller, M. C., Kennedy, J. L., Kenny, E., Kent, L., Kim, Y., Kirov, G. K., Klauck, S. M., Klei, L., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krabbendam, L., Krasucki, R., Kuntsi, J., Kwan, P., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Ledbetter, D. H., Lee, P. H., Lencz, T., Lesch, K. P., Levinson, D. F., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Liu, C., Lohoff, F. W., Loo, S. K., Lord, C., Lowe, J. K., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Maestrini, E., Magnusson, P. K. E., Mahon, P. B., Maier, W., Malhotra, A. K., Mane, S. M., Martin, C. L., Martin, N. G., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S. A., McGhee, K. A., McGough, J. J., McGrath, P. J., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McLean, A. W., McMahon, F. J., McMahon, W. M., McQuillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Meyer, J., Middeldorp, C. M., Middleton, L., Milanova, V., Miranda, A., Monaco, A. P., Montgomery, G. W., Moran, J. L., Moreno-De Luca, D., Morken, G., Morris, D. W., Morrow, E. M., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Murtha, M., Myers, R. M., Myin-Germeys, I., Neale, M. C., Nelson, S. F., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V. L., Nolen, W. A., Nöthen, M. M., Nurnberger, J. I., Nwulia, E. A., Nyholt, DR., O'Dushlaine, C., Oades, R. D., Olincy, A., Oliveira, G., Olsen, L., Ophoff, R. A., Osby, U., Owen, M. J., Palotie, A., Parr, J. R., Paterson, A. D., Pato, C. N., Pato, M. T., Penninx, B. W. J. H., Pergadia, M. L., Pericak-Vance, M. A., Pickard, B. S., Pimm, J., Piven, J., Posthuma, D., Potash, J. B., Poustka, F., Propping, P., Puri, V., Quested, D., Quinn, E. M., Ramos-Quiroga, J. A., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Ribasés, M., Rice, J. P., Rietschel, M., Roeder, K., Roeyers, H., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Sanders, S. J., Santangelo, S., Sergeant, J. A., Schachar, R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Scherer, S. W., Schork, N. J., Schulze, T. G., Schumacher, J., Schwarz, M., Scolnick, E., Scott, L. J., Shi, J., Shilling, P. D., Shyn, S. I., Silverman, J. M., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E. J., St Clair, D., State, M., Steffens, M., Steinhausen, H. C., Strauss, J., Strohmaier, J., Stroup, T. S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Todorov, A. A., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J. C. G., Grootheest, G., van Os, J., Vicente, A., Vieland, V., Vincent, J. B., Visscher, P. M., Walsh, C. A., Wassink, T. H., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Wijsman, E. M., Willemsen, G., Williams, N., Willsey, A. J., Witt, S. H., Xu, W., Young, A. H., Yu, T. W., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S., Devlin, B., Kelsoe, J., Sklar, P., Daly, M. J., O'Donovan, M. C., Craddock, N., Sullivan, P. F., Smoller, J. W., Kendler, K. S. & Wray, N. R., 2013, In : Nature Genetics. 45, 9, p. 984-994

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Major Depressive Disorder
  • Single Nucleotide Polymorphism
  • Schizophrenia
  • Bipolar Disorder
  • Psychiatry

• Genetic risk profiles for depression and anxiety in adult and elderly cohorts

  Demirkan, A., Penninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlinden, A. G., Hottenga, J. J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. & 1 others, Middeldorp, C. M., 2011, In : Molecular Psychiatry. 16, 7, p. 773-783

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Genetic Profile
  • Anxiety
  • Elderly
  • Depression
  • Genome-Wide Association Study

• Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders

  Ligthart, L., Hottenga, J. J., Lewis, C. M., Farmer, A. E., Craig, I. W., Breen, G., Willemsen, G., Vink, J. M., Middeldorp, C. M., Byrne, E. M., Heath, A. C., Madden, P. A. F., Pergadia, M. L., Montgomery, G. W., Martin, N. G., Penninx, B. W. J. H., McGuffin, P., Boomsma, D. I. & Nyholt, DR., 2014, In : Human Genetics. 133, 2, p. 173-186 14 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Migraine Disorders
  • Major Depressive Disorder
  • Depression
  • Genome-Wide Association Study
  • Major Depressive Disorder 1

• Genetic Variation at the TPH2 Gene Influences Impulsivity in Addition to Eating Disorders

  Slof-Op 't Landt, M. C. T., Bartels, M., Middeldorp, C. M., van Beijsterveldt, C. E. M., Slagboom, P. E., Boomsma, D. I., van Furth, E. F. & Meulenbelt, I., 2013, In : Behavior Genetics. 43, 1, p. 24-33

  Research output: Contribution to Journal › Article › Academic › peer-review

  • eating disorders
  • Tryptophan Hydroxylase
  • genetic variation
  • Impulsive Behavior
  • Feeding and Eating Disorders

• Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

  Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Blokhuis, M. M., Horikoshi, M., Hottenga, J. J., Middeldorp, C. M., Uitterlinden, A. G., Plomin, R., Boomsma, D. I., Heinrich, J., Melbye, M., Rivadeneira, F. & 7 others, Hakonarson, H., Ring, S. M., Davey Smith, G., Sørensen, T. I. A., Timpson, N. J., Grant, S. F. A. & Jaddoe, V. W. V., 2016, In : Human Molecular Genetics. 25, 2, p. 389-403

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

• Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth pubertal timing and childhood adiposity

  Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., Groen-Blokhuis, M. M., Kreiner-Møller, E., Marinelli, M., Holst, C., Leinonen, J. T., Perry, J. R., Surakka, I., Pietilainen, O. P., Kettunen, J., Anttila, V. & 269 others, Kaakinen, M., Sovio, U., Pouta, A., Das, S., Lagou, V., Power, C., Prokopenko, I., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Palotie, A., Kajantie, E., Osmond, C., Lehtimäki, T., Viikari, J. S., Kähönen, M., Warrington, N. M., Lye, S. J., Palmer, L. J., Tiesler, C. M. T., Flexeder, C., Montgomery, G. W., Medland, S. E., Hofman, A., Hakonarson, H., Guxens, M., Bartels, M., Salomaa, V., Adair, L. S., Atalay, M., van Beijsterveldt, C. E. M., Bergen, N., Benke, K. S., Charoen, P., Coin, L., Cooper, C., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Feenstra, B., Frayling, T. M., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M. W., Goh, L. K., Hattersley, A. T., Haworth, C. M., Hadley, D., Hedebrand, J., Hinney, A., Hirschhorn, J. N., Hocher, B., Holloway, J. W., Hottenga, J. J., Horikoshi, M., Iñiguez, C., Järvelin, M. R., Kilpeläinen, T. O., Kirin, M., Kowgier, M., Lakka, H. M., Lakka, T. A., Lange, L. A., Lawlor, D. A., Lewin, A., Lindgren, C. M., Lindi, V., Maggi, R., Marsh, J., Melbye, M., Middeldorp, C. M., Millwood, I., Mohlke, K. L., Mook-Kanamori, D. O., Murray, J. C., Nivard, M. G., Nohr, E. A., Ntalla, I., Oken, E., Ong, K. K., O'Reilly, P. F., Panoutsopoulou, K., Pararajasingham, J., Pearson, E. R., Price, T. S., Rodriguez, A., Salem, R. M., Saw, S. M., Scherag, A., Sebert, S., Siitonen, N., Simell, O., Strachan, D. P., Sunyer, J., Teo, Y. Y., Uitterlinden, A. G., Valcárcel, B., White, S., Widén, E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zeggini, E., Elks, C. E., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Gudbjartsson, D. F., Esko, T., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K. E., Smith, E. N., Ulivi, S., Warrington, M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Coviello, A. D., d'Adamo, P., de Faire, U., de Geus, E. J. C., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hu, F. B., Illig, T., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., McArdle, W. L., Mooser, V., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Porcu, E., Rafnar, T., Rice, J. P., Rivadeneira, F., Rudan, I., Sala, C., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V., Shuldiner, A. R., Soranzo, N., Srinivasan, S. R., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D., Weedon, M. N., Wichmann, H. E., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Murray, A., Murabito, J. M., Kaprio, J., Sørensen, T. I. A., Ballester, F., Bisgaard, H., Boomsma, D. I., Koppelman, G. H., Grant, S. F., Jaddoe, V. W., Martin, N. G., Heinrich, J., Raitakari, O. T., Eriksson, J. G., Smith, G. D., Hyppönen, E., McCarthy, M. I. & Ripatti, S., 2013, In : Human Molecular Genetics. 22, 13, p. 2735-2747

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Genetic Loci
  • Genome-Wide Association Study
  • Adiposity
  • Puberty
  • Growth

• Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

  Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., Kutalik, Z., Lee, S. H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N. R., Arolt, V., Baune, B. T., Boomsma, D. I., Børglum, A. D., Byrne, E. M., Castelao, E., Craddock, N. & 31 others, Craig, I. W., Dannlowski, U., Deary, I. J., Degenhardt, F., Forstner, A. J., Gordon, S. D., Grabe, H. J., Grove, J., Hamilton, S. P., Hayward, C., Heath, A. C., Hocking, L. J., Homuth, G., Hottenga, J. J., Kloiber, S., Krogh, J., Landén, M., Lang, M., Levinson, D. F., Lichtenstein, P., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Middeldorp, C. M., Milaneschi, Y., Penninx, B. W. J. H., Smit, J. H. & CONVERGE Consortium, CARDIoGRAM Consortium, GERAD1 Consortium, 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 325-335 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Major Depressive Disorder
  • Genomics
  • Age of Onset
  • Psychiatry
  • Genome

• Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

  Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D. J., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Lopezz de Alda, M., Alliey-Rodriguez, N. & 31 others, Andreassen, O. A., Babadjanova, G., Bass, N. J., Bauer, M., Baune, B. T., Bellivier, F., Bergen, S. E., Bethell, A., Biernacka, J. M., Blackwood, D. H. R., Boks, M. P., Boomsma, D. I., Børglum, A. D., Borrmann-Hassenbach, M., Brennan, P., Budde, M., Buttenschøn, H. N., Byrne, E. M., Cervantes, P., Clarke, T. K., Craddock, N., Cruceanu, C., Curtis, D., de Geus, E. J. C., Fischer, S. B., Hottenga, J-J., Middeldorp, C. M., Milaneschi, Y., Penninx, B. W. J. H., Willemsen, G. & Bipolar Disorders Working Group of the Psychiatric Genomics Consortium, 20 Jun 2017, In : Translational Psychiatry. 7, 6, p. e1155

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Borderline Personality Disorder
  • Genome-Wide Association Study
  • Bipolar Disorder
  • Schizophrenia
  • Depression

• Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

  Wray, N. R., Pergadia, M. L., Blackwood, D. H., Penninx, B. W. J. H., Gordon, S. D., Nyholt, DR., Ripke, S., MacIntyre, D. J., McGhee, K. A., Maclean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., de Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., van den Oord, E. J. C. G., Liu, J. Z. & 12 others, Macgregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Madden, P. A. F. & Sullivan, P. F., 2012, In : Molecular Psychiatry. 17, 1, p. 36-48

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Genome-Wide Association Study
  • Major Depressive Disorder
  • Meta-Analysis
  • Single Nucleotide Polymorphism
  • adenylate cyclase 3

• Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

  Cousminer, D. L., Stergiakouli, E., Berry, D. J., Ang, W., Blokhuis, M. M., Körner, A., Siitonen, N., Ntalla, I., Marinelli, M., Perry, J. R. B., Kettunen, J., Jansen, R., Surakka, I., Timpson, N. J., Ring, S., McMahon, G., Power, C., Wang, C., Kähönen, M., Viikari, J. & 24 others, Lehtimäki, T., Middeldorp, C. M., van Beijsterveldt, C. E. M., Hulshoff Pol, H. E., Neef, R. M., Weise, S., Pahkala, K., Niinikoski, H., Zeggini, E., Panoutsopoulou, K., Bustamante, M., Penninx, B. W. J. H., Murabito, J., Torrent, M., Dedoussis, G. V., Kiess, W., Boomsma, D. I., Pennell, C. E., Raitakari, O. T., Hyppönen, E., Davey Smith, G., Ripatti, S., McCarthy, M. I. & Widen, E., 2014, In : Human Molecular Genetics. 23, 16, p. 4452-4464 13 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Sexual Maturation
  • Menarche
  • Puberty
  • Genome-Wide Association Study
  • myocardin

• Genome-Wide Association Uncovers Shared Genetic Effects Among Personality Traits and Mood States

  Luciano, M., Huffman, J. E., Arias-Vasquez, A., Vinkhuyzen, A. A. E., Middeldorp, C. M., Giegling, I., Payton, A., Davies, G. E., Zgaga, L., Janzing, J. G., Ke, X. Y., Galesloot, T., Hartmann, A. M., Ollier, W., Tenesa, A., Hayward, C., Verhagen, M., Montgomery, G. W., Hottenga, J. J., Konte, B. & 24 others, Starr, J. M., Vitart, V., Vos, P. E., Madden, P. A. F., Willemsen, G., Konnerth, H., Horan, M. A., Porteous, D. J., Campbell, H., Vermeulen, S. H., Heath, A. C., Wright, A., Polasek, O., Kovacevic, S. B., Hastie, N., Franke, B., Boomsma, D. I., Martin, N. G., Rujescu, D., Wilson, J. F., Buitelaar, J., Pendleton, N., Rudan, I. & Deary, I. J., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 6, p. 684-695

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Personality
  • Single Nucleotide Polymorphism
  • Genome
  • Psychology
  • Extraversion (Psychology)

• Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

  Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T. M., McGrath, J., Hickie, I. B., Hansell, N. K., Wright, M. J., Gillespie, N. A., Forstner, A. J., Schulze, T. G., Wüst, S., Nöthen, M. M., Baumgartner, M. R., Walker, B. R., Crawford, A. A. & 12 others, Colodro-Conde, L., Medland, S. E., Martin, N. G., Rietschel, M., CORtisolNETwork (CORNET) Consortium, Abdellaoui, A., de Geus, E., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Willemsen, G. & Boomsma, D. I., 10 Nov 2017, In : Scientific Reports. 7, 1, p. 15351 15351.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Twins
  • Hair
  • Psychological Stress
  • Hydrocortisone
  • Genes

• Heritability and genomics of gene expression in peripheral blood

  Wright, F. A., Sullivan, P. F., Brooks, A. I., Zou, F., Sun, W., Xia, K., Madar, V., Jansen, R., Chung, W., Zhou, Y. H., Abdellaoui, A., Batista, S., Butler, C., Chen, G., Chen, T. H., D’Ambrosio, D., Gallins, P., Ha, M. J., Hottenga, J. J., Huang, S. & 18 others, Kattenberg, V. M., Kochar, J., Middeldorp, C. M., Qu, A., Shabalin, A., Tischfield, J., Todd, L., Tzeng, J. Y., Grootheest, G., Vink, J. M., Wang, Q., Wang, W., Willemsen, G., Smit, J. H., de Geus, E. J. C., Yin, Z., Penninx, B. W. J. H. & Boomsma, D. I., 2014, In : Nature Genetics. 46, 5, p. 430-437 8 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Quantitative Trait Loci
  • Genomics
  • Gene Expression
  • Genetic Transcription
  • Genes