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  • A.H.M. Willemsen
2020

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Beekman, A. F. T., Jansen, R., Milaneschi, Y., Peyrot, W. J., Smit, J. H., W J H Penninx, B. & Posthuma, D., 16 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to JournalArticle

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D. & Willemsen, G., Mar 2020, In : Biological Psychiatry. 87, 5, p. 419-430 12 p.

Research output: Contribution to JournalArticle

Open Access

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

Li, C., Stoma, S., Lotta, L. A., Warner, S., Albrecht, E., Allione, A., Arp, P. P., Broer, L., Buxton, J. L., Da Silva Couto Alves, A., Deelen, J., Fedko, I. O., Gordon, S. D., Jiang, T., Karlsson, R., Kerrison, N., Loe, T. K., Mangino, M., Milaneschi, Y., Miraglio, B. & 76 others, Pervjakova, N., Russo, A., Surakka, I., van der Spek, A., Verhoeven, J. E., Amin, N., Beekman, M., Blakemore, A. I., Canzian, F., Hamby, S. E., Hottenga, J-J., Jones, P. D., Jousilahti, P., Mägi, R., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Perola, M., Pietiläinen, K. H., Salomaa, V., Sillanpää, E., Suchiman, H. E., van Heemst, D., Willemsen, G., Agudo, A., Boeing, H., Boomsma, D. I., Chirlaque, M-D., Fagherazzi, G., Ferrari, P., Franks, P., Gieger, C., Eriksson, J. G., Gunter, M., Hägg, S., Hovatta, I., Imaz, L., Kaprio, J., Kaaks, R., Key, T., Krogh, V., Martin, N. G., Melander, O., Metspalu, A., Moreno, C., Onland-Moret, N. C., Nilsson, P., Ong, K. K., Overvad, K., Palli, D., Panico, S., Pedersen, N. L., Penninx, B. W. J. H., Quirós, J. R., Jarvelin, M. R., Rodríguez-Barranco, M., Scott, R. A., Severi, G., Slagboom, P. E., Spector, T. D., Tjonneland, A., Trichopoulou, A., Tumino, R., Uitterlinden, A. G., van der Schouw, Y. T., van Duijn, C. M., Weiderpass, E., Denchi, E. L., Matullo, G., Butterworth, A. S., Danesh, J., Samani, N. J., Wareham, N. J., Nelson, C. P., Langenberg, C. & Codd, V., 5 Mar 2020, In : American Journal of Human Genetics. 106, 3, p. 389-404 16 p.

Research output: Contribution to JournalArticle

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Beekman, A. T. F., Jansen, R., Milaneschi, Y., Smit, J. H., W J H Penninx, B. & Posthuma, D., 23 Jan 2020, In : Molecular Psychiatry.

Research output: Contribution to JournalArticle

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

BBMRI Metabolomics Consortium, 7 Jan 2020, In : Nature Communications. 11, 1, p. 39 39.

Research output: Contribution to JournalArticle

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

Liu, J., Lahousse, L., Nivard, M. G., Bot, M., Chen, L., van Klinken, J. B., Thesing, C. S., Beekman, M., van den Akker, E. B., Slieker, R. C., Waterham, E., van der Kallen, C. J. H., de Boer, I., Li-Gao, R., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L. J. M., Murad, S. D. & 29 others, Uitterlinden, A. G., Willemsen, G., Pool, R., Milaneschi, Y., van Heemst, D., Suchiman, H. E. D., Rutters, F., Elders, P. J. M., Beulens, J. W. J., van der Heijden, A. A. W. A., van Greevenbroek, M. M. J., Arts, I. C. W., Onderwater, G. L. J., van den Maagdenberg, A. M. J. M., Mook-Kanamori, D. O., Hankemeier, T., Terwindt, G. M., Stehouwer, C. D. A., Geleijnse, J. M., 't Hart, L. M., Slagboom, P. E., van Dijk, K. W., Zhernakova, A., Fu, J., Penninx, B. W. J. H., Boomsma, D. I., Demirkan, A., Stricker, B. H. C. & van Duijn, C. M., Jan 2020, In : Nature Medicine. 26, 1, p. 110-117 8 p.

Research output: Contribution to JournalArticle

Substance use: Interplay between polygenic risk and neighborhood environment

Pasman, J. A., Verweij, K. J. H., Abdellaoui, A., Hottenga, J. J., Fedko, I. O., Willemsen, G., Boomsma, D. I. & Vink, J. M., 28 Feb 2020, In : Drug and Alcohol Dependence. 209, p. 107948 107948.

Research output: Contribution to JournalArticle

An Extended Twin-Pedigree Study of Neuroticism in the Netherlands Twin Register

Boomsma, D. I., Helmer, Q., Nieuwboer, H. A., Hottenga, J. J., de Moor, M. H., van den Berg, S. M., Davies, G. E., Vink, J. M., Schouten, M. J., Dolan, C. V., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Ligthart, L. & de Geus, E. J., 1 Jan 2018, In : Behavior Genetics. 48, 1, p. 1-11

Research output: Contribution to JournalArticle

Open Access
Open Access

Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project

Jelenkovic, A., Yokoyama, Y., Sund, R., Hur, Y. M., Harris, J. R., Brandt, I., Nilsen, T. S., Ooki, S., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Saudino, K. J., Stazi, M. A., Fagnani, C., Brescianini, S., Nelson, T. L., Whitfield, K. E., Knafo-Noam, A., Mankuta, D., Abramson, L. & 30 others, Cutler, T. L., Hopper, J. L., Llewellyn, C. H., Fisher, A., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Krueger, R. F., McGue, M., Pahlen, S., Alexandra Burt, S., Klump, K. L., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Willemsen, G., Bartels, M., van Beijsterveld, C. E. M., Craig, J. M., Saffery, R., Rasmussen, F., Tynelius, P., Heikkilä, K. & Boomsma, D. I., May 2018, In : Early Human Development. 120, p. 53-60 8 p.

Research output: Contribution to JournalArticle

Open Access

Bidirectional prospective associations between cardiac autonomic activity and inflammatory markers

Hu, M. X., Lamers, F., Neijts, M., Willemsen, G., De Geus, E. J. C. & Penninx, B. W. J. H., 1 Jun 2018, In : Psychosomatic Medicine. 80, 5, p. 475-482 8 p.

Research output: Contribution to JournalArticle

Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts

Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y. M., Ullemar, V., Almqvist, C., Magnusson, P. K., Willemsen, G., Bartels, M., Beijsterveldt, C. E. V., Bogl, L. H., Pietiläinen, K. H., Vuoksimaa, E., Ji, F., Ning, F., Pang, Z., Nelson, T. L., Whitfield, K. E., Rebato, E., Llewellyn, C. H. & 30 others, Fisher, A., Bayasgalan, G., Narandalai, D., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Stazi, M. A., Fagnani, C., Brescianini, S., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Cutler, T. L., Hopper, J. L., Krueger, R. F., McGue, M., Pahlen, S., Craig, J. M., Saffery, R., Haworth, C. M., Plomin, R., Knafo-Noam, A., Mankuta, D., Abramson, L. & Boomsma, D. I., 19 Apr 2018, In : Scientific Reports. 8, 1, 6300.

Research output: Contribution to JournalArticle

Open Access

Brain reward responses to food stimuli among female monozygotic twins discordant for BMI

Doornweerd, S., De Geus, E. J., Barkhof, F., van Bloemendaal, L., Boomsma, D. I., van Dongen, J., Drent, M. L., Willemsen, G., Veltman, D. J. & IJzerman, R. G., 8 Jun 2018, In : Brain Imaging and Behavior. 12, 3, p. 718-727 10 p.

Research output: Contribution to JournalArticle

Open Access

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

van der Lee, S. J., Teunissen, C. E., Pool, R., Shipley, M. J., Teumer, A., Chouraki, V., Melo van Lent, D., Tynkkynen, J., Fischer, K., Hernesniemi, J., Haller, T., Singh-Manoux, A., Verhoeven, A., Willemsen, G., de Leeuw, F. A., Wagner, H., van Dongen, J., Hertel, J., Budde, K., Willems van Dijk, K. & 28 others, Weinhold, L., Ikram, M. A., Pietzner, M., Perola, M., Wagner, M., Friedrich, N., Slagboom, P. E., Scheltens, P., Yang, Q., Gertzen, R. E., Egert, S., Li, S., Hankemeier, T., van Beijsterveldt, C. E. M., Vasan, R. S., Maier, W., Peeters, C. F. W., Jörgen Grabe, H., Ramirez, A., Seshadri, S., Metspalu, A., Kivimäki, M., Salomaa, V., Demirkan, A., Boomsma, D. I., van der Flier, W. M., Amin, N. & van Duijn, C. M., Jun 2018, In : Alzheimers & Dementia. 14, 6, p. 707-722 16 p.

Research output: Contribution to JournalArticle

Open Access

Cohort profile: the Geoscience and Health Cohort Consortium (GECCO) in the Netherlands

Timmermans, E. J., Lakerveld, J., Beulens, J. W. J., Boomsma, D. I., Kramer, S. E., Oosterman, M., Willemsen, G., Stam, M., Nijpels, G., Schuengel, C., Smit, J. H., Brunekreef, B., Dekkers, J. E. C., Deeg, D. J. H., Penninx, B. W. J. H. & Huisman, M., 9 Jun 2018, In : BMJ Open. 8, 6, p. 1-14 14 p., e021597.

Research output: Contribution to JournalArticle

Open Access

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M. & 73 others, Araya, R., Bowes, L., Burns, M. R., Byrne, E. M., Coffey, J. C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J-J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., Meyer zu Schwabedissen, H., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van der Auwera, S., Wainwright, N. W., Wang, J-C., Willemsen, G., Anderson, I. M., Arolt, V., Åslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., de Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T. C., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, D. M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M. A., Nurnberger, J. I., Breslau, N. & Bierut, L. J., 2 Jan 2018, In : Molecular Psychiatry. 23, 1, p. 133-142 10 p.

Research output: Contribution to JournalArticle

DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis

Ward-Caviness, C. K., Huffman, J. E., Everett, K., Germain, M., Van Dongen, J., Hill, W. D., Jhun, M. A., Brody, J. A., Ghanbari, M., Du, L., Roetker, N. S., De Vries, P. S., Waldenberger, M., Gieger, C., Wolf, P., Prokisch, H., Koenig, W., O’Donnell, C. J., Levy, D., Liu, C. & 34 others, Truong, V., Wells, P. S., Trégouët, D. A., Tang, W., Morrison, A. C., Boerwinkle, E., Wiggins, K. L., McKnight, B., Guo, X., Psaty, B. M., Sotoodenia, N., Boomsma, D. I., Willemsen, G., Ligthart, L., Deary, I. J., Zhao, W., Ware, E. B., Kardia, S. L. R., Van Meurs, J. B. J., Uitterlinden, A. G., Franco, O. H., Eriksson, P., Franco-Cereceda, A., Pankow, J. S., Johnson, A. D., Gagnon, F., Morange, P. E., De Geus, E. J. C., Starr, J. M., Smith, J. A., Dehghan, A., Björck, H. M., Smith, N. L. & Peters, A., 25 Oct 2018, In : Blood. 132, 17, p. 1842-1850 9 p.

Research output: Contribution to JournalArticle

DNA methylation signatures of educational attainment

Dongen, J. V., Bonder, M. J., Dekkers, K. F., Nivard, M. G., Iterson, M. V., Willemsen, G., Beekman, M., Spek, A. V. D., Meurs, J. B. J. V., Franke, L., Heijmans, B. T., Duijn, C. M. V., Slagboom, P. E. & Boomsma, D. I., 23 Mar 2018, In : npj Science of Learning 2018 3:1. 3, p. 1-14 14 p., 7.

Research output: Contribution to JournalArticle

Open Access

Erratum to Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

The 23andMe Research Team & AAGC collaborators, 16 Aug 2018, In : Nature Genetics. 50, 9, 1 p.

Research output: Contribution to JournalComment / Letter to the editor

Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and 'Omics' Studies

Odintsova, V. V., Willemsen, G., Dolan, C. V., Hottenga, J. J., Martin, N. G., Slagboom, P. E., Ordoñana, J. R. & Boomsma, D. I., Jun 2018, In : Twin Research and Human Genetics. 21, 3, p. 239-252 14 p.

Research output: Contribution to JournalArticle

Open Access

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

23Andme Research Team, Abdellaoui, A., Peyrot, W. J., Hottenga, J. J., Vinkhuyzen, A. A. E., Willemsen, G., Boomsma, D. I., van Duijn, C. M., Penninx, B., Posthuma, D. & Uitterlinden, A. G., Aug 2018, In : Nature Genetics. 50, 8, p. 1112-1121 10 p.

Research output: Contribution to JournalArticle

Open Access
File

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Oct 2018, In : Nature Genetics. 50, 10, p. 1412-1431 20 p.

Research output: Contribution to JournalArticle

Genetic and environmental factors affecting birth size variation: A pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts

Yokoyama, Y., Jelenkovic, A., Hur, Y. M., Sund, R., Fagnani, C., Stazi, M. A., Brescianini, S., Ji, F., Ning, F., Pang, Z., Knafo-Noam, A., Mankuta, D., Abramson, L., Rebato, E., Hopper, J. L., Cutler, T. L., Saudino, K. J., Nelson, T. L., Whitfield, K. E., Corley, R. P. & 40 others, Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Llewellyn, C. H., Fisher, A., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Krueger, R. F., McGue, M., Pahlen, S., Bartels, M., Van Beijsterveldt, C. E. M., Willemsen, G., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Rasmussen, F., Tynelius, P., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Rose, R. J., Pietiläinen, K. H., Sørensen, T. I. A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 1 Aug 2018, In : International Journal of Epidemiology. 47, 4, p. 1195-1206 12 p.

Research output: Contribution to JournalArticle

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

LifeLines Cohort Study & CHARGE Inflammation Working Group, 1 Nov 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

Research output: Contribution to JournalArticle

Open Access

Genome-wide analysis of DNA methylation in buccal cells: A study of monozygotic twins and mQTLs

Van Dongen, J., Ehli, E. A., Jansen, R., Van Beijsterveldt, C. E. M., Willemsen, G., Hottenga, J. J., Kallsen, N. A., Peyton, S. A., Breeze, C. E., Kluft, C., Heijmans, B. T., Bartels, M., Davies, G. E. & Boomsma, D. I., 25 Sep 2018, In : Epigenetics and Chromatin. 11, p. 1-14 14 p., 54.

Research output: Contribution to JournalArticle

Open Access

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 30 others, Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Posthuma, D., Smit, J. H., Willemsen, G., Boomsma, D. I. & Penninx, B. W. J. H., May 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to JournalArticle

Open Access
File

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

23Andme Research Team, 16 Jul 2018, In : Nature Genetics. 50, 8, p. 1072-1080 9 p.

Research output: Contribution to JournalLetter

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

Hysi, P. G., Valdes, A. M., Liu, F., Furlotte, N. A., Evans, D. M., Bataille, V., Visconti, A., Hemani, G., McMahon, G., Ring, S. M., Smith, G. D., Duffy, D. L., Zhu, G., Gordon, S. D., Medland, S. E., Lin, B. D., Willemsen, G., Hottenga, J. J., Vuckovic, D., Girotto, G. & 24 others, Gandin, I., Sala, C., Concas, M. P., Brumat, M., Gasparini, P., Toniolo, D., Cocca, M., Robino, A., Yazar, S., Hewitt, A. W., Chen, Y., Zeng, C., Uitterlinden, A. G., Ikram, M. A., Hamer, M. A., Van Duijn, C. M., Nijsten, T., MacKey, D. A., Falchi, M., Boomsma, D. I., Martin, N. G., Hinds, D. A., Kayser, M. & Spector, T. D., May 2018, In : Nature Genetics. 50, 5, p. 652-656 5 p.

Research output: Contribution to JournalArticle

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J-J., Allard, C., Barton, S. J., Espinosa, A. & 31 others, Marsh, J. A., Potter, C., Zhang, G., Ang, W., Berry, D. J., Bouchard, L., Das, S., Hakonarson, H., Heikkinen, J., Helgeland, Ø., Hocher, B., Hofman, A., Inskip, H. M., Jones, S. E., Kogevinas, M., Lind, P. A., Marullo, L., Medland, S. E., Murray, A., Murray, J. C., Njølstad, P. R., Nohr, E. A., Reichetzeder, C., Ring, S. M., Ruth, K. S., Santa-Marina, L., Scholtens, D. M., Willemsen, G., Bartels, M., Boomsma, D. I. & Early Growth Genetics (EGG) Consortium, 1 Feb 2018, In : Human Molecular Genetics. 27, 4, p. 742-756 15 p., ddx429.

Research output: Contribution to JournalArticle

Open Access

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 20 Dec 2018, In : PLoS ONE. 13, 12, p. 1-29 29 p., e0209160.

Research output: Contribution to JournalArticle

Open Access

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Gudmundsdottir, V., Pedersen, H. K., Allebrandt, K. V., Brorsson, C., van Leeuwen, N., Banasik, K., Mahajan, A., Groves, C. J., van de Bunt, M., Dawed, A. Y., Fritsche, A., Staiger, H., Simonis-Bik, A. M. C., Deelen, J., Kramer, M. H. H., Dietrich, A., Hübschle, T., Willemsen, G., Häring, H-U., de Geus, E. J. C. & 8 others, Boomsma, D. I., Eekhoff, E. M. W., Ferrer, J., McCarthy, M. I., Pearson, E. R., Gupta, R., Brunak, S. & 't Hart, L. M., 2 Jan 2018, In : PLoS ONE. 13, 1, p. e0189886 e0189886.

Research output: Contribution to JournalArticle

Open Access

Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative

Boomsma, D. I., Davies, G. E., de Geus, E., Ehli, E. A., Finnicum, C. T. F., Mbarek, H., Willemsen, G. & MiBioGen Consortium Initiative, 8 Jun 2018, In : Microbiome. 6, 1, p. 101 101.

Research output: Contribution to JournalArticle

Open Access

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, Herder, C., Rathmann, W., Roden, M., Gieger, C., Kramer, M. H. H., van Heemst, D., Pedersen, H. K., Gudmundsdottir, V., Schulze, M. B., Pischon, T., de Geus, E. J. C., Boeing, H., Boomsma, D. I., Ziegler, A. G., Slagboom, P. E., Hummel, S., Beekman, M., Grallert, H., Brunak, S., McCarthy, M. I., Gupta, R., Pearson, E. R., Adamski, J. & 't Hart, L. M., 1 Jan 2018, In : Diabetologia. 61, 1, p. 117-129 13 p.

Research output: Contribution to JournalArticle

Open Access

Metataxonomic Analysis of Individuals at BMI Extremes and Monozygotic Twins Discordant for BMI

Finnicum, C. T., Doornweerd, S., Dolan, C. V., Luningham, J. M., Beck, J. J., Willemsen, G., Ehli, E. A., Boomsma, D. I., Ijzerman, R. G., Davies, G. E. & De Geus, E. J. C., 1 Jun 2018, In : Twin Research and Human Genetics. 21, 3, p. 203-213 11 p.

Research output: Contribution to JournalArticle

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Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E. & 31 others, Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Heckbert, S. R., Hottenga, J., Mbarek, H., Willemsen, G. & Australian Asthma Genetics Consortium (AAGC) collaborators, Jan 2018, In : Nature Genetics. 50, 1, p. 42-53 12 p.

Research output: Contribution to JournalArticle

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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Dec 2018, In : Nature Genetics. 50, 12, p. 1755-1755 1 p.

Research output: Contribution to JournalErratum

Selective maternal seeding and environment shape the human gut microbiome

Korpela, K., Costea, P., Coelho, L. P., Kandels-Lewis, S., Willemsen, G., Boomsma, D. I., Segata, N. & Bork, P., 1 Apr 2018, In : Genome Research. 28, 4, p. 561-568 8 p.

Research output: Contribution to JournalArticle

Open Access

Testing familial transmission of smoking with two different research designs

Treur, J. L., Verweij, K. J. H., Abdellaoui, A., Fedko, I. O., de Zeeuw, E. L., Ehli, E. A., Davies, G. E., Hottenga, J. J., Willemsen, G., Boomsma, D. I. & Vink, J. M., 7 Jun 2018, In : Nicotine and Tobacco Research. 20, 7, p. 836-842 7 p.

Research output: Contribution to JournalArticle

Open Access
2017

2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio

Lin, B. D., Carnero-Montoro, E., Bell, J. T., Boomsma, D. I., de Geus, E. J., Jansen, R., Kluft, C., Mangino, M., Penninx, B., Spector, T. D., Willemsen, G. & Hottenga, J-J., Nov 2017, In : Journal of human genetics. 62, 11, p. 979-988 10 p.

Research output: Contribution to JournalArticle

A framework for the detection of de novo mutations in family-based sequencing data

Francioli, L. C., Cretu-Stancu, M., Garimella, K. V., Fromer, M., Kloosterman, W. P., Boomsma, D. I., Abdellaoui, A., Hottenga, J. J., Willemsen, G., Samocha, K. E., Neale, B. M., Daly, M. J., Banks, E., DePristo, M. A. & Bakker, P. I. W., Jan 2017, In : European Journal of Human Genetics. 25, 2, p. 227-233 7 p.

Research output: Contribution to JournalArticle

Open Access

A method to customize population-specific arrays for genome-wide association testing

Ehli, E. A., Abdellaoui, A., Fedko, I. O., Grieser, C., Nohzadeh-Malakshah, S., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Davies, G. E. & Hottenga, J. J., 1 Feb 2017, In : European Journal of Human Genetics. 25, 2, p. 267-270 4 p.

Research output: Contribution to JournalArticle

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

Direk, N., Williams, S., Smith, J. A., Ripke, S., Air, T., Amare, A. T., Amin, N., Baune, B. T., Bennett, D. A., Blackwood, D. H. R., Boomsma, D., Breen, G., Buttenschøn, H. N., Byrne, E. M., Børglum, A. D., Castelao, E., Cichon, S., Clarke, T-K., Cornelis, M. C., Dannlowski, U. & 82 others, De Jager, P. L., Demirkan, A., Domenici, E., van Duijn, C. M., Dunn, E. C., Eriksson, J. G., Esko, T., Faul, J. D., Ferrucci, L., Fornage, M., de Geus, E., Gill, M., Gordon, S. D., Grabe, H-J., van Grootheest, G., Hamilton, S. P., Hartman, C. A., Heath, A. C., Hek, K., Hofman, A., Homuth, G., Horn, C., Jan Hottenga, J., Kardia, S. L. R., Kloiber, S., Koenen, K., Kutalik, Z., Ladwig, K-H., Lahti, J., Levinson, D. F., Lewis, C. M., Lewis, G., Li, Q. S., Llewellyn, D. J., Lucae, S., Lunetta, K. L., MacIntyre, D. J., Madden, P. A. F., Martin, N. G., McIntosh, A. M., Metspalu, A., Milaneschi, Y., Montgomery, G. W., Mors, O., Mosley, T. H., Murabito, J. M., Müller-Myhsok, B., Nöthen, M. M., Nyholt, D. R., O'Donovan, M. C., Penninx, B. W., Pergadia, M. L., Perlis, R., Potash, J. B., Preisig, M., Purcell, S. M., Quiroz, J. A., Räikkönen, K., Rice, J. P., Rietschel, M., Rivera, M., Schulze, T. G., Shi, J., Shyn, S. I., Sinnamon, G. C., Smit, J. H., Smoller, J. W., Snieder, H., Tanaka, T., Tansey, K. E., Teumer, A., Uher, R., Umbricht, D., Van der Auwera, S., Ware, E. B., Weir, D. R., Weissman, M. M., Willemsen, G., Yang, J., Zhao, W., Tiemeier, H. & Sullivan, P. F., 1 Aug 2017, In : Biological Psychiatry. 82, 5, p. 322-329 8 p.

Research output: Contribution to JournalArticle

Association between birthweight and later body mass index: an individual-based pooled analysis of 27 twin cohorts participating in the CODATwins project

Jelenkovic, A., Yokoyama, Y., Sund, R., Pietiläinen, K. H., Hur, Y-M., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Ooki, S., Saudino, K. J., Stazi, M. A., Fagnani, C., D'Ippolito, C., Nelson, T. L., Whitfield, K. E., Knafo-Noam, A., Mankuta, D., Abramson, L., Heikkilä, K., Cutler, T. L. & 46 others, Hopper, J. L., Wardle, J., Llewellyn, C. H., Fisher, A., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Burt, S. A., Klump, K. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Dubois, L., Boivin, M., Brendgen, M. R., Dionne, G., Vitaro, F., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Rasmussen, F., Tynelius, P., Bayasgalan, G., Narandalai, D., Haworth, C. M., Plomin, R., Ji, F., Ning, F., Pang, Z., Rebato, E., Krueger, R. F., McGue, M., Pahlen, S., Boomsma, D. I., Sørensen, T. I., Kaprio, J. & Silventoinen, K., 1 Oct 2017, In : International Journal of Epidemiology. 46, 5, p. 1488-1498 11 p.

Research output: Contribution to JournalArticle

Open Access

Design and implementation of a customized genotyping array for imputation-based genome-wide association studies: the Avera-NTR Global Screening Array

Beck, J. J., Ehli, E. A., مبارك, ., Kallsen, N., Peyton, S., Abdellaoui, A., Fedko, I. O., Willemsen, G., de Geus, E., Boomsma, D. I., Davies, G. E. & Hottenga, J. J., 6 Mar 2017.

Research output: Contribution to ConferencePosterOther research output

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Differences in genetic and environmental variation in adult body mass index by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts

Silventoinen, K., Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y-M., Cozen, W., Hwang, A. E., Mack, T. M., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Tomizawa, R., Pietiläinen, K. H., Rissanen, A., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q. & 82 others, Zhang, D., Pang, Z., Piirtola, M., Aaltonen, S., Öncel, S. Y., Aliev, F., Rebato, E., Hjelmborg, J. V. B., Christensen, K., Skytthe, A., Kyvik, K. O., Silberg, J. L., Eaves, L. J., Cutler, T. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Song, Y-M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H-U., Swan, G. E., Krasnow, R., Magnusson, P. K., Pedersen, N. L., Dahl Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Spector, T. D., Mangino, M., LaChance, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Huibregtse, B. M., Bartels, M., van Beijsterveldt, C. E., Willemsen, G., Goldberg, J. H., Rasmussen, F., Tarnoki, A. D., Tarnoki, D. L., Derom, C. A., Vlietinck, R. F., Loos, R. J., Hopper, J. L., Sung, J., Maes, H. H., Turkheimer, E., Boomsma, D. I., Sørensen, T. I. & Kaprio, J., 1 Aug 2017, In : American Journal of Clinical Nutrition. 106, 2, p. 457-466 10 p.

Research output: Contribution to JournalArticle

Differential gene expression patterns between smokers and non-smokers: cause or consequence?

Vink, J. M., Jansen, R., Brooks, A., Willemsen, G., van Grootheest, G., de Geus, E., Smit, J. H., Penninx, B. W. & Boomsma, D. I., Mar 2017, In : Addiction Biology. 22, 2, p. 550-560 11 p.

Research output: Contribution to JournalArticle

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Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts

Bogl, L. H., Jelenkovic, A., Vuoksimaa, E., Ahrenfeldt, L., Pietiläinen, K. H., Stazi, M. A., Fagnani, C., D'Ippolito, C., Hur, Y-M., Jeong, H-U., Silberg, J. L., Eaves, L. J., Maes, H. H., Bayasgalan, G., Narandalai, D., Cutler, T. L., Kandler, C., Jang, K. L., Christensen, K., Skytthe, A. & 56 others, Kyvik, K. O., Cozen, W., Hwang, A. E., Mack, T. M., Derom, C. A., Vlietinck, R. F., Nelson, T. L., Whitfield, K. E., Corley, R. P., Huibregtse, B. M., McAdams, T. A., Eley, T. C., Gregory, A. M., Krueger, R. F., McGue, M., Pahlen, S., Willemsen, G., Bartels, M., Pang, Z., Tan, Q., Zhang, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Hjelmborg, J. V. B., Rebato, E., Swan, G. E., Krasnow, R., Busjahn, A., Lichtenstein, P., Öncel, S. Y., Aliev, F., Baker, L. A., Tuvblad, C., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Duncan, G. E., Buchwald, D., Tarnoki, A. D., Tarnoki, D. L., Yokoyama, Y., Hopper, J. L., Loos, R. J. F., Boomsma, D. I., Sørensen, T. I. A., Silventoinen, K., Kaprio, J. & van Beijsterveldt, C. E. M., 2017, In : Biology of sex differences. 8, 1, p. 14 14.

Research output: Contribution to JournalArticle

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