Find Research Outputs

Search concepts
Selected filters

Publication Year

  • 2019
  • 2018
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Lannie Ligthart
2019

Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies

Doering, S., Lichtenstein, P., Gillberg, C., Boomsma, D. I., Van Beijsterveldt, T. C. E. M., Ligthart, L., Willemsen, G., De Geus, E., Middeldorp, C. M., Bartels, M., Kuja-Halkola, R. & Lundström, S., 14 Nov 2019, In : BMC Psychiatry. 19, 1, p. 1-11 11 p., 363.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

BBMRI Metabolomics Consortium, 16 Apr 2019, In : Neurology. 92, 16, p. e1899-e1911 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Open Access
2018

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, 22 Jun 2018, In : Science. 360, 6395, p. 1-15 15 p., 8757.

Research output: Contribution to JournalArticleAcademicpeer-review

An Extended Twin-Pedigree Study of Neuroticism in the Netherlands Twin Register

Boomsma, D. I., Helmer, Q., Nieuwboer, H. A., Hottenga, J. J., de Moor, M. H., van den Berg, S. M., Davies, G. E., Vink, J. M., Schouten, M. J., Dolan, C. V., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Ligthart, L. & de Geus, E. J., 1 Jan 2018, In : Behavior Genetics. 48, 1, p. 1-11

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Are Migraine and Tension-Type Headache Genetically Related? An Investigation of Twin Family Data

Ligthart, L., Huijgen, A., Willemsen, G., De Geus, E. J. C. & Boomsma, D. I., Apr 2018, In : Twin Research and Human Genetics. 21, 2, p. 112-118 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

Boomsma, D. I., Ligthart, L., Posthuma, D. & 23Andme Research Team, 16 May 2018, In : Neuron. 98, 4, p. 743-753.e4

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis

Ward-Caviness, C. K., Huffman, J. E., Everett, K., Germain, M., Van Dongen, J., Hill, W. D., Jhun, M. A., Brody, J. A., Ghanbari, M., Du, L., Roetker, N. S., De Vries, P. S., Waldenberger, M., Gieger, C., Wolf, P., Prokisch, H., Koenig, W., O’Donnell, C. J., Levy, D., Liu, C. & 34 others, Truong, V., Wells, P. S., Trégouët, D. A., Tang, W., Morrison, A. C., Boerwinkle, E., Wiggins, K. L., McKnight, B., Guo, X., Psaty, B. M., Sotoodenia, N., Boomsma, D. I., Willemsen, G., Ligthart, L., Deary, I. J., Zhao, W., Ware, E. B., Kardia, S. L. R., Van Meurs, J. B. J., Uitterlinden, A. G., Franco, O. H., Eriksson, P., Franco-Cereceda, A., Pankow, J. S., Johnson, A. D., Gagnon, F., Morange, P. E., De Geus, E. J. C., Starr, J. M., Smith, J. A., Dehghan, A., Björck, H. M., Smith, N. L. & Peters, A., 25 Oct 2018, In : Blood. 132, 17, p. 1842-1850 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Molecular genetic overlap between migraine and major depressive disorder

The International Headache Genetics Consortium, 1 Aug 2018, In : European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Polygenic risk for alcohol consumption and its association with alcohol-related phenotypes: Do stress and life satisfaction moderate these relationships?

Mies, G. W., Verweij, K. J. H., Treur, J. L., Ligthart, L., Fedko, I. O., Hottenga, J. J., Willemsen, G., Bartels, M., Boomsma, D. I. & Vink, J. M., 1 Jan 2018, In : Drug and Alcohol Dependence. 183, p. 7-12 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Shared Genetics of Temporomandibular Disorder Pain and Neck Pain: Results of a Twin Study

Visscher, C. M., Schouten, M. J., Ligthart, L., van Houtem, C. M., de Jongh, A. & Boomsma, D. I., Apr 2018, In : Journal of oral & facial pain and headache. 32, 2, p. 107-112 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23Andme Research Team, 26 Nov 2018, In : Nature Neuroscience. 21, 12, p. 1656-1669 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2016

Epigenome-wide association study meta-analysis of aggressive behavior

van Dongen, J., Ismail, K., Mulder, R., Baselmans, B. M. L., Nivard, M. G., Jansen, R., Ligthart, L., Ollikainen, M., Vuoksimaa, E., Tiemeier, H., Kaprio, J., Bartels, M. & Boomsma, D., Nov 2016, In : Behavior Genetics. 46, 6, p. 810-810

Research output: Contribution to JournalMeeting AbstractOther research output

Evidence for Gender-Dependent Genotype by Environment Interaction in Adult Depression

Molenaar, D., Middeldorp, C. M., Willemsen, G., Ligthart, L., Nivard, M. G. & Boomsma, D. I., 2016, In : Behavior Genetics. 46, 1, p. 59-71

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Gene-based pleiotropy across migraine with aura and migraine without aura patient groups

Zhao, H., Eising, E., de Vries, B., Vijfhuizen, L. S., Anttila, V., Winsvold, B. S., Kurth, T., Stefansson, H., Kallela, M., Malik, R., Stam, A. H., Arfan Ikram, M., Ligthart, L., Freilinger, T., Alexander, M., Müller-Myhsok, B., Schreiber, S., Meitinger, T., Aromas, A., Eriksson, J. G. & 16 others, Boomsma, D. I., van Duijn, C. M., Zwart, J. A., Quaye, L., Kubisch, C., Dichgans, M., Wessman, M., Stefansson, K., Chasman, D. I., Palotie, A., Martin, N. G., Montgomery, G. W., Ferrari, M. D., Terwindt, G. M., van den Maagdenberg, A. M. J. M. & Nyholt, DR., 2016, In : Cephalalgia. 36, 7, p. 648-657

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic epidemiology of migraine and depression

Yang, Y., Ligthart, L., Terwindt, G. M., Boomsma, D. I., Rodriguez-Acevedo, A. J. & Nyholt, DR., 2016, In : Cephalalgia. 36, 7, p. 679-691

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide pleiotropy of adult aggression and blood metabolites

Hagenbeek, F. A., Nivard, M. G., Pool, R., van Dongen, J., Hottenga, J. J., Abdellaoui, A., Willemsen, G., Vink, J. M., Ligthart, L., Harms, A., Hankemeier, T., Bartels, M. & Boomsma, D. I., 2016, In : Behavior Genetics. 46, 6, p. 772-816

Research output: Contribution to JournalMeeting AbstractOther research output

Heritability of high sugar consumption through drinks and the genetic correlation with substance use

Treur, J. L., Boomsma, D. I., Ligthart, L., Willemsen, G. & Vink, J. M., 2016, In : American Journal of Clinical Nutrition. 104, 4, p. 1144-1150

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T., Ran, C., Gordon, S. G., Stam, A. H. & 88 others, Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Gudlaug Hrafnsdottir, M., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M. A., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Kurki, M. I., Kals, M., Mägi, R., Pärn, K., Hämaläinen, E., Huang, H., Byrnes, A. E., Franke, L., Huang, J., Stergiakouli, E., Lee, P. H., Sandor, C., Webber, C., Cader, Z., Müller-Myhsok, B., Schreiber, S., Meitinger, T., Eriksson, J. G., Salomaa, V., Heikkilä, K., Loehrer, A. G., Uitterlinden, A. G., Hofman, A., van Duijn, C. M., Cherkas, L., Pedersen, L., Stubhaug, A., Nielsen, C. S., Männikkö, M., Mihailov, E., Milani, L., Göbel, H., Esserlind, A. L., Francke Christensen, A., Folkmann Hansen, T., Werge, T., Kaprio, J., Aromaa, A., Raitakari, O., Ikram, M. A., Spector, T. D., Järvelin, M. R., Metspalu, A., Kubisch, C., Strachan, D. P., Ferrari, M. D., Belin, A. C., Dichgans, M., Wessman, M., van den Maagdenberg, A. M. J. M., Zwart, J. A., Boomsma, D. I., Davey Smith, G., Stefansson, K., Eriksson, N., Daly, M. J., Neale, B. M., Olesen, J., Chasman, D. I., Nyholt, DR., Palotie, A. & Posthuma, D., 2016, In : Nature Genetics. 48, 8, p. 856-866

Research output: Contribution to JournalArticleAcademicpeer-review

2015

Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies

Nyholt, DR., Anttila, V., Winsvold, B. S., Kurth, T., Stefansson, H., Kallela, M., Malik, R., de Vries, B., Terwindt, G. M., Arfan Ikram, M., Stam, A. H., Ligthart, L., Freilinger, T., Alexander, M., Müller-Myhsok, B., Schreiber, S., Meitinger, T., Aromaa, A., Eriksson, J. G., Kaprio, J. & 16 others, Boomsma, D. I., van Duijn, C. M., Raitakari, O. T., Järvelin, M. R., Zwart, J. A., Quaye, L., Strachan, D. P., Kubisch, C., Ferrari, M. D., van den Maagdenberg, A. M. J. M., Dichgans, M., Wessman, M., Davey Smith, G., Stefansson, K., Chasman, D. I. & Palotie, A., 2015, In : Cephalalgia. 35, 6, p. 489-499 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Epigenome-Wide Association Study of Aggressive Behavior

van Dongen, J., Nivard, M. G., Baselmans, B. M. L., Rodrigues Zilhao Nogueira, N., Ligthart, L., Heijmans, B. T., Bartels, M. & Boomsma, D. I., 2015, In : Twin Research and Human Genetics. 18, 6, p. 686-698 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder

Jacobsen, K. K., Nievergelt, C. M., Zayats, T., Greenwood, T. A., Anttila, V., Akiskal, H. S., Ligthart, L., Hottenga, J. J., Vink, J. M., Penninx, B. W. J. H., Boomsma, D. I., Haavik, J., Fasmer, O. B., Kelsoe, J. R., Johansson, S. & Oedegaard, K. J., 2015, In : Journal of Affective Disorders. 172, p. 453-461 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Self-reported gagging in dentistry: prevalence, psycho-social correlates and oral health

van Houtem, C. M. H. H., van Wijk, A. J., Boomsma, D. I., Ligthart, L., Visscher, C. M. & de Jongh, A., 2015, In : Journal of Oral Rehabilitation. 42, 7, p. 487-494 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants

Malik, R., Freilinger, T., Winsvold, B. S., Anttila, V., van der Heiden, J., Traylor, M., de Vries, B., Holliday, E. G., Terwindt, G. M., Sturm, J., Bis, J. C., Hopewell, J. C., Ferrari, M. D., Rannikmae, K., Wessman, M., Kallela, M., Kubisch, C., Fornage, M., Meschia, J. F., Lehtimäki, T. & 32 others, Sudlow, C., Clarke, R., Chasman, D. I., Mitchell, B. D., Maguire, J., Kaprio, J., Farrall, M., Raitakari, O. T., Kurth, T., Arfan Ikram, M., Reiner, A. P., Longstreth, J. W. T., Rothwell, P. M., Strachan, D. P., Sharma, P., Seshadri, S., Quaye, L., Cherkas, L., Schürks, M., Rosand, J., Ligthart, L., Boncoraglio, G. B., Davey Smith, G., van Duijn, C. M., Stefansson, K., Worrall, B. B., Nyholt, DR., Markus, H. S., van den Maagdenberg, A. M. J. M., Cotsapas, C., Zwart, J. A. & Palotie, A., 2015, In : Neurology. 84, 21, p. 2132-2145

Research output: Contribution to JournalArticleAcademicpeer-review

2014

Comorbidity among multiple pain symptoms and anxious depression in a Dutch population sample

Ligthart, L., Visscher, C. M., van Houtem, C. M. H. H., Geels, L. M., Vink, J. M., de Jongh, A. & Boomsma, D. I., 2014, In : Journal of Pain. 15, 9, p. 945-955 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders

Ligthart, L., Hottenga, J. J., Lewis, C. M., Farmer, A. E., Craig, I. W., Breen, G., Willemsen, G., Vink, J. M., Middeldorp, C. M., Byrne, E. M., Heath, A. C., Madden, P. A. F., Pergadia, M. L., Montgomery, G. W., Martin, N. G., Penninx, B. W. J. H., McGuffin, P., Boomsma, D. I. & Nyholt, DR., 2014, In : Human Genetics. 133, 2, p. 173-186 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetisch onderzoek met behulp van tweelingen

Ligthart, L., 2014, In : Quality Practice. Nascholingstijdschrift voor tandartsen. 9, 5, p. 8-11 4 p.

Research output: Contribution to JournalArticle

Is dental phobia a blood-injection-injury phobia?

van Houtem, C. M. H. H., Aartman, I. H. A., Boomsma, D. I., Ligthart, L., Visscher, C. & de Jongh, A., 2014, In : Depression and Anxiety. 31, 12, p. 1026-1034 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Prevalence and comorbidity of pain symptoms in the general population

Ligthart, L., 2014.

Research output: Contribution to ConferencePosterOther research output

2013

Anxiety and Depression Are Associated With Migraine and Pain in General: An Investigation of the Interrelationships

Ligthart, L., Gerrits, M. J. G., Boomsma, D. I. & Penninx, B. W. J. H., 2013, In : Journal of Pain. 14, 4, p. 363-370

Research output: Contribution to JournalArticleAcademicpeer-review

A review and meta-analysis of the heritability of specific phobia subtypes and corresponding fears

van Houtem, C. M. H. H., Laine, M. L., Boomsma, D. I., Ligthart, L., van Wijk, A. J. & de Jongh, A., 2013, In : Journal of Anxiety Disorders. 27, 4, p. 379-388

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide meta-analysis identifies new susceptibility loci for migraine

Anttila, V., Winsvold, B. S., Gormley, P., Kurth, T., Bettella, F., McMahon, G., Kallela, M., Malik, R., de Vries, B., Terwindt, G., Medland, S. E., Todt, U., McArdle, W. L., Quaye, L., Koiranen, M., Ikram, M. A., Lehtimäki, T., Stam, A. H., Ligthart, L., Wedenoja, J. & 75 others, Dunham, I., Neale, B. M., Palta, P., Hamalainen, E., Schürks, M., Rose, L. M., Buring, J. E., Ridker, P. M., Steinberg, S., Stefansson, H., Jakobsson, F., Lawlor, D. A., Evans, D. M., Ring, S. M., Färkkilä, M., Artto, V., Kaunisto, M. A., Freilinger, T., Schoenen, J., Frants, R. R., Pelzer, N., Weller, C. M., Zielman, R., Heath, A. C., Madden, P. A. F., Montgomery, G. W., Martin, N. G., Borck, G., Göbel, H., Heinze, A., Heinze-Kuhn, K., Williams, F. M., Hartikainen, A-L., Pouta, A., van den Ende, J., Uitterlinden, A. G., Hofman, A., Amin, N., Hottenga, J. J., Vink, J. M., Heikkilä, K., Alexander, M., Muller-Myhsok, B., Schreiber, S., Meitinger, T., Wichmann, H. E., Aromaa, A., Eriksson, J. G., Traynor, B. J., Trabzuni, D., Rossin, E., Lage, K., Jacobs, S. B., Gibbs, J. R., Birney, E., Kaprio, J., Penninx, B. W. J. H., Boomsma, D. I., van Duijn, C. M., Raitakari, O., Jarvelin, M-R., Zwart, J. A., Cherkas, L., Strachan, D. P., Kubisch, C., Ferrari, M. D., van den Maagdenberg, A. M. J. M., Dichgans, M., Wessman, M., Smith, G. D., Stefansson, K., Daly, M. J., Nyholt, DR., Chasman, D. I. & Palotie, A., 2013, In : Nature Genetics. 45, 8, p. 912-917

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Is tmd-pijn erfelijk?

Visscher, C. M., Ligthart, L. & Lobbezoo, F., 2013, In : Quality Practice. Nascholingstijdschrift voor tandartsen. 8, 4, p. 12-14

Research output: Contribution to JournalArticle

The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection

Willemsen, G., Vink, J. M., Abdellaoui, A., den Braber, A., van Beek, J. H. D. A., Draisma, H. H. M., van Dongen, J., van t Ent, D., Geels, L. M., van Lien, R., Ligthart, L., Kattenberg, V. M., Mbarek, H., de Moor, M. H. M., Neijts, M., Pool, R., Stroo, N., Kluft, C., Suchiman, H. E. D., Slagboom, P. E. & 2 others, de Geus, E. J. C. & Boomsma, D. I., 2013, In : Twin Research and Human Genetics. 16, 1, p. 271-281

Research output: Contribution to JournalArticleAcademicpeer-review

2012

Sex Differences in Genetic Architecture of Complex Phenotypes?

Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M., van Dongen, J., van Beek, J. H. D. A., Distel, M. A., de Moor, M. H. M., Smit, D. J. A., Minica, C. C., Ligthart, L., Geels, L. M., Abdellaoui, A., Middeldorp, C. M., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Boomsma, D. I., 2012, In : PLoS ONE. 7, 12, e47371.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
2011

Adolescent personality profiles, neighborhood income, and young adult alcohol use: A longitudinal study

Ayer, L., Rettew, D., Althoff, R. R., Willemsen, G., Ligthart, L., Hudziak, J. J. & Boomsma, D. I., 2011, In : Addictive Behaviors. 36, 12, p. 1301-1304

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analysis of genome-wide association for migraine in six population-based European cohorts

Ligthart, L., de Vries, B., Smith, A. V., Arfan Ikram, M., Amin, N., Hottenga, J. J., Koelewijn, S. C., Kattenberg, V. M., de Moor, M. H. M., Janssens, A. J. W., Aulchenko, Y. S., Oostra, B. A., de Geus, E. J. C., Smit, J. H., Zitman, F. G., Uitterlinden, A. G., Hofman, A., Willemsen, G., Nyholt, DR., Montgomery, G. W. & 9 others, Terwindt, G. M., Gudnason, V., Penninx, B. W. J. H., Breteler, M., Ferrari, M. D., Launer, L. J., van Duijn, C. M., van den Maagdenberg, A. M. J. M. & Boomsma, D. I., 2011, In : European Journal of Human Genetics. 19, 8, p. 901-907

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Migraine, depression and other types of pain: a common etiology?

Ligthart, L., 2011.

Research output: Contribution to ConferencePosterOther research output

Qualitative and quantitative sex differences in genetic architecture for human phenotypes

Boomsma, D. I., Bartels, M., van Beijsterveldt, C. E. M., Distel, M. A., Smit, D. J. A., de Moor, M. H. M., Middeldorp, M., Ligthart, R. S. L., Willemsen, G., Hottenga, J. J., de Geus, E. J. C. & Vink, J. M., 2011, In : Behavior Genetics. 41, 6, p. 894-895

Research output: Contribution to JournalMeeting AbstractOther research output

Open Access
File