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Author

  • W.M.A. Niessen
2015

Identification of novel bioactives on the alpha-7-nAChR using an at-line cellular bioassay after nanofractionation

Otvos, R. A., Mladic, M., Alpizar, G. A., Niessen, W. M. A., Somsen, G. W., Smit, A. B. & Kool, J., Sep 2015, In : European Neuropsychopharmacology. 25, p. S244-S245

Research output: Contribution to JournalArticleAcademicpeer-review

Metabolic profiling of ligands for the chemokine receptor CXCR3 by liquid chromatography-mass spectrometry coupled to bioaffinity assessment

Mladic, M., Scholten, D. J., Wijtmans, M., Falck, D., Leurs, R., Niessen, W. M. A., Smit, M. J. & Kool, J., Sep 2015, In : Analytical and Bioanalytical Chemistry. 407, 23, p. 7067-81 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Solution-phase electrochemistry-nuclear magnetic resonance of small organic molecules

Falck, D. & Niessen, W. M. A., 2015, In : TrAC. Trends in Analytical Chemistry. 70, p. 31-39

Research output: Contribution to JournalArticleAcademicpeer-review

2016

At-line cellular screening methodology for identification of bioactives in mixtures targeting the alpha7-n AChR.

Ötvös, R. A., Mladic, M., Arias-Alpizar, G., Niessen, W. M. A., Somsen, G. W., Smit, A. B. & Kool, J., 2016, In : Journal of Biomolecular Screening. 21, p. 459-467

Research output: Contribution to JournalArticleAcademicpeer-review

At-line nanofractionation with parallel mass spectrometry and bioactivity assessment for the rapid screening of thrombin and factor Xa inhibitors in snake vemoms.

Mladic, M., Zietek, B. M., Krishnamoorthy Iyer, J., Hermarij, P., Niessen, W. M. A., Somsen, G. W., Kini, R. M. & Kool, J., 2016, In : Toxicon. 110, p. 79-89

Research output: Contribution to JournalArticleAcademicpeer-review

Development of an online cell-based bioactivity screening method by couplling liquid chromatography in flow cytometry with parallel mass spectrometry.

Ötvös, R. A., van Nierop, P., Niessen, W. M. A., Manjunatha Kini, R., Somsen, G. W., Smit, A. B. & Kool, J., 2016, In : Analytical Chemistry. 88, p. 4825-4832

Research output: Contribution to JournalArticleAcademicpeer-review

2018

LC–MS/MS assay for assessing medical adherence in patients under warfarin maintenance therapy

Farouk, F., Nabhan, S., Niessen, W. M. A. & Azzazy, H. M. E., 1 Sep 2018, In : Microchemical Journal. 141, p. 135-140 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Nanofractionation Platform with Parallel Mass Spectrometry for Identification of CYP1A2 Inhibitors in Metabolic Mixtures

Zietek, B. M., Mladic, M., Bruyneel, B., Niessen, W. M. A., Honing, M., Somsen, G. W. & Kool, J., Mar 2018, In : SLAS Discovery. 23, 3, p. 283-293 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling

Slagboom, J., Otvos, R. A., Cardoso, F. C., Iyer, J., Visser, J. C., van Doodewaerd, B. R., McCleary, R. J. R., Niessen, W. M. A., Somsen, G. W., Lewis, R. J., Kini, R. M., Smit, A. B., Casewell, N. R. & Kool, J., 15 Jun 2018, In : Toxicon. 148, p. 213-222 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access