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  • Andrea Maier
2013

Lower proportion of naive peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people

Derhovanessian, E., Maier, A. B., Hahnel, K., Zelba, H., De Craen, A. J. M., Roelofs, H., Slagboom, E. P., Westendorp, R. G. J. & Pawelec, G., Aug 2013, In : Age. 35, 4, p. 1387-1399 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Lower susceptibility to cerebral small vessel disease in human familial longevity: The Leiden longevity study

Altmann-Schneider, I., Van Der Grond, J., Slagboom, P. E., Westendorp, R. G. J., Maier, A. B., Van Buchem, M. A. & De Craen, A. J. M., Jan 2013, In : Stroke. 44, 1, p. 9-14 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Metabolic health in families enriched for longevity is associated with low prevalence of hand osteoarthritis and influences OA biomarker profiles

Bos, S. D., Beekman, M., Maier, A. B., Karsdal, M. A., Kwok, W. Y., Bay-Jensen, A. C., Kloppenburg, M., Slagboom, P. E. & Meulenbelt, I., Oct 2013, In : Annals of the Rheumatic Diseases. 72, 10, p. 1669-1674 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

More than half of hip fracture patients do not regain mobility in the first postoperative year

Vochteloo, A. J. H., Moerman, S., Tuinebreijer, W. E., Maier, A. B., de Vries, M. R., Bloem, R. M., Nelissen, R. G. H. H. & Pilot, P., Apr 2013, In : Geriatrics and Gerontology International. 13, 2, p. 334-341 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Muscle strength rather than muscle mass is associated with standing balance in elderly outpatients

Bijlsma, A. Y., Pasma, J. H., Lambers, D., Stijntjes, M., Blauw, G. J., Meskers, C. G. M. & Maier, A. B., Jul 2013, In : Journal of the American Medical Directors Association. 14, 7, p. 493-8 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Parasitic infections and immune function: Effect of helminth infections in a malaria endemic area

Boef, A. G. C., May, L., van Bodegom, D., van Lieshout, L., Verweij, J. J., Maier, A. B., Westendorp, R. G. J. & Eriksson, U. K., May 2013, In : Immunobiology. 218, 5, p. 706-711 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Physiological and functional evaluation of healthy young and older men and women: design of the European MyoAge study

McPhee, J. S., Hogrel, J-Y., Maier, A. B., Seppet, E., Seynnes, O. R., Sipilä, S., Bottinelli, R., Barnouin, Y., Bijlsma, A. Y., Gapeyeva, H., Maden-Wilkinson, T. M., Meskers, C. G., Pääsuke, M., Sillanpää, E., Stenroth, L., Butler-Browne, G., Narici, M. V. & Jones, D. A., Jun 2013, In : Biogerontology. 14, 3, p. 325-37 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Pro-inflammatory capacity of classically activated monocytes relates positively to muscle mass and strength

Beenakker, K. G. M., Westendorp, R. G. J., de Craen, A. J. M., Slagboom, P. E., van Heemst, D. & Maier, A. B., Aug 2013, In : Aging Cell. 12, 4, p. 682-9 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Serum insulin-like growth factor 1 and facial ageing: High levels associate with reduced skin wrinkling in a cross-sectional study

Noordam, R., Gunn, D. A., Tomlin, C. C., Maier, A. B., Maier, A. B., Griffiths, T., Catt, S. D., Ogden, S., Slagboom, P. E., Slagboom, P. E., Westendorp, R. G. J., Westendorp, R. G. J., Griffiths, C. E. M., Van Heemst, D., Van Heemst, D., De Craen, A. J. M. & De Craen, A. J. M., Mar 2013, In : British Journal of Dermatology. 168, 3, p. 533-538 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Signalling pathways regulating muscle mass in ageing skeletal muscle: the role of the IGF1-Akt-mTOR-FoxO pathway

Sandri, M., Barberi, L., Bijlsma, A. Y., Blaauw, B., Dyar, K. A., Milan, G., Mammucari, C., Meskers, C. G. M., Pallafacchina, G., Paoli, A., Pion, D., Roceri, M., Romanello, V., Serrano, A. L., Toniolo, L., Larsson, L., Maier, A. B., Muñoz-Cánoves, P., Musarò, A., Pende, M. & 3 others, Reggiani, C., Rizzuto, R. & Schiaffino, S., Jun 2013, In : Biogerontology. 14, 3, p. 303-23 21 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Stand van Zaken: Sarcopenie: Op weg naar klinische toepasbaarheid

Translated title of the contribution: Sarcopenia: Toward its clinical utilizationBijlsma, A. Y., Meskers, C. G. M., Westendorp, R. G. J. & Maier, A. B., 2013, In : Nederlands Tijdschrift voor Geneeskunde. 157, 19, A5336.

Research output: Contribution to JournalArticleAcademicpeer-review

Targeted Biomarker Discovery by High Throughput Glycosylation Profiling of Human Plasma Alpha1-Antitrypsin and Immunoglobulin A

Ruhaak, L. R., Koeleman, C. A. M., Uh, H. W., Stam, J. C., van Heemst, D., Maier, A. B., Houwing-Duistermaat, J. J., Hensbergen, P. J., Slagboom, P. E., Deelder, A. M. & Wuhrer, M., 9 Sep 2013, In : PLoS ONE. 8, 9, e73082.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The influence of ageing on the development and management of rheumatoid arthritis

Boots, A. M. H., Maier, A. B., Stinissen, P., Masson, P., Lories, R. J. & De Keyser, F., 18 Jun 2013, In : Nature Reviews Rheumatology. 9, 10, p. 604-613 10 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

The reply

Taekema, D. G. & Maier, A. B., Jun 2013, In : The American Journal of Medicine. 126, 6, p. e11-2

Research output: Contribution to JournalArticleAcademicpeer-review

Wnt signaling potentiates nevogenesis

Pawlikowski, J. S., McBryan, T., van Tuyn, J., Drotar, M. E., Hewitt, R. N., Maier, A. B., King, A., Blyth, K., Wu, H. & Adams, P. D., 1 Oct 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 40, p. 16009-14 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2012

Brain tissue volumes in familial longevity: The Leiden Longevity Study

Altmann-Schneider, I., de Craen, A. J. M., Slagboom, P. E., Westendorp, R. G. J., van Buchem, M. A., Maier, A. B. & van der Grond, J., Dec 2012, In : Aging Cell. 11, 6, p. 933-939 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Chronic inhibition of the respiratory chain in human fibroblast cultures: Differential responses related to subject chronological and biological age

Dekker, P., Van Baalen, L. M., Dirks, R. W., Slagboom, P. E., Van Heemst, D., Tanke, H. J., Westendorp, R. G. J. & Maier, A. B., May 2012, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 67 A, 5, p. 456-464 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Chronology of age-related disease definitions: Osteoporosis and sarcopenia

Bijlsma, A. Y., Meskers, C. G. M., Westendorp, R. G. J. & Maier, A. B., Apr 2012, In : Ageing Research Reviews. 11, 2, p. 320-324 5 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

CMV and Immunosenescence: From basics to clinics

Solana, R., Tarazona, R., Aiello, A. E., Akbar, A. N., Appay, V., Beswick, M., Bosch, J. A., Campos, C., Cantisán, S., Cicin-Sain, L., Derhovanessian, E., Ferrando-Martínez, S., Frasca, D., Fulöp, T., Govind, S., Grubeck-Loebenstein, B., Hill, A., Hurme, M., Kern, F., Larbi, A. & 17 others, López-Botet, M., Maier, A. B., McElhaney, J. E., Moss, P., Naumova, E., Nikolich-Zugich, J., Pera, A., Rector, J. L., Riddell, N., Sanchez-Correa, B., Sansoni, P., Sauce, D., van Lier, R., Wang, G. C., Wills, M. R., Zieliński, M. & Pawelec, G., 31 Oct 2012, In : Immunity and Ageing. 9, p. 1-9 9 p., 23.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Cortisol serum levels in familial longevity and perceived age: The Leiden Longevity Study

Noordam, R., Gunn, D. A., Tomlin, C. C., Rozing, M. P., Maier, A. B., Slagboom, P. E., Westendorp, R. G. J., van Heemst, D. & De Craen, A. J. M., Oct 2012, In : Psychoneuroendocrinology. 37, 10, p. 1669-1675 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Cytomegalovirus seropositivity is associated with glucose regulation in the oldest old. Results from the Leiden 85-plus Study

Chen, S., De Craen, A. J. M., Raz, Y., Derhovanessian, E., Vossen, A. C. T. M., Westendorp, R. G. J., Pawelec, G. & Maier, A. B., 28 Aug 2012, In : Immunity and Ageing. 9, p. 1-7 7 p., 18.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Early-life environment influencing susceptibility to cytomegalovirus infection: Evidence from the Leiden Longevity Study and the Longitudinal Study of Aging Danish Twins

Mortensen, L. H., Maier, A. B., Slagbom, P. E., Pawelec, G., Derhovanessian, E., Petersen, I., Jahn, G., Westendorp, R. G. J. & Christensen, K., May 2012, In : Epidemiology and Infection. 140, 5, p. 835-841 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Familial longevity is marked by lower diurnal salivary cortisol levels: The Leiden longevity study

Noordam, R., Jansen, S. W. M., Akintola, A. A., Oei, N. Y. L., Oei, N. Y. L., Oei, N. Y. L., Maier, A. B., Maier, A. B., Pijl, H., Slagboom, P. E., Slagboom, P. E., Westendorp, R. G. J., Westendorp, R. G. J., van der Grond, J., de Craen, A. J. M., de Craen, A. J. M., van Heemst, D. & van Heemst, D., 13 Feb 2012, In : PLoS ONE. 7, 2, e31166.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Handgrip strength at midlife and familial longevity: The Leiden Longevity Study

Ling, C. H. Y., De Craen, A. J. M., Eline Slagboom, P., Westendorp, R. G. J. & Maier, A. B., Oct 2012, In : Age. 34, 5, p. 1261-1268 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

High blood pressure and resilience to physical and cognitive decline in the oldest old: The leiden 85-plus study

Sabayan, B., Oleksik, A. M., Maier, A. B., Van Buchem, M. A., Poortvliet, R. K. E., De Ruijter, W., Gussekloo, J., De Craen, A. J. M. & Westendorp, R. G. J., Nov 2012, In : Journal of the American Geriatrics Society. 60, 11, p. 2014-2019 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Human in vivo longevity is reflected in vitro by differential metabolism as measured by 1H-NMR profiling of cell culture supernatants

Dekker, P., Meissner, A., Dirks, R. W., Eline Slagboom, P., Van Heemst, D., Deelder, A. M., Tanke, H. J., Westendorp, R. G. J. & Maier, A. B., Mar 2012, In : Molecular BioSystems. 8, 3, p. 783-789 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Levels of 25-hydroxyvitamin D in familial longevity: The Leiden Longevity Study

Noordam, R., De Craen, A. J. M., Pedram, P., Maier, A. B., Mooijaart, S. P., Van Pelt, J., Feskens, E. J., Streppel, M. T., Slagboom, P. E., Westendorp, R. G. J., Beekman, M. & Van Heemst, D., 11 Dec 2012, In : CMAJ. 184, 18

Research output: Contribution to JournalArticleAcademicpeer-review

Marked heterogeneity in growth characteristics of myoblast clonal cultures and myoblast mixed cultures obtained from the same individual

Maier, A. B., Cohen, R., Blom, J., Van Heemst, D. & Westendorp, R. G. J., Feb 2012, In : Gerontology. 58, 2, p. 150-155 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts

Dekker, P., Gunn, D., McBryan, T., Dirks, R. W., van Heemst, D., Lim, F. L., Jochemsen, A. G., Verlaan-de Vries, M., Nagel, J., Adams, P. D., Tanke, H. J., Westendorp, R. G. J. & Maier, A. B., Jul 2012, In : Mechanisms of Ageing and Development. 133, 7, p. 498-507 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Monitoring of ubiquitin-proteasome activity in living cells using a degron (dgn)-destabilized green fluorescent protein (GFP)-based reporter protein

Greussing, R., Unterluggauer, H., Koziel, R., Maier, A. B. & Jansen-Dürr, P., 11 Oct 2012, In : Journal of Visualized Experiments. 69

Research output: Contribution to JournalArticleAcademicpeer-review

Monitoring walking and cycling of middle-aged to older community dwellers using wireless wearable accelerometers

Zhang, Y., Beenakker, K. G. M., Butala, P. M., Lin, C. C., Little, T. D. C., Maier, A. B., Stijntjes, M., Vartanian, R. & Wagenaar, R. C., 12 Nov 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012. IEEE, p. 158-161 4 p. (Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference).

Research output: Chapter in Book / Report / Conference proceedingConference contributionAcademicpeer-review

Morphometric skin characteristics dependent on chronological and biological age: The Leiden Longevity Study

Waaijer, M. E. C., Gunn, D. A., Catt, S. D., Van Ginkel, M., De Craen, A. J. M., Hudson, N. M., Van Heemst, D., Slagboom, P. E., Westendorp, R. G. J. & Maier, A. B., Dec 2012, In : Age. 34, 6, p. 1543-1552 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Muscle characteristics in patients with chronic systemic inflammation

Beenakker, K. G. M., Duijnisveld, B. J., Van Der Linden, H. M. J., Visser, C. P. J., Westendorp, R. G. J., Butler-Brown, G., Nelissen, R. G. H. H. & Maier, A. B., Aug 2012, In : Muscle and Nerve. 46, 2, p. 204-209 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Predicting discharge location of hip fracture patients; the new discharge of hip fracture patients score

Vochteloo, A. J. H., Tuinebreijer, W. E., Maier, A. B., Nelissen, R. G. H. H., Bloem, R. M. & Pilot, P., Aug 2012, In : International Orthopaedics. 36, 8, p. 1709-1714 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Predicting survival in oldest old people

Taekema, D. G., Gussekloo, J., Westendorp, R. G. J., De Craen, A. J. M. & Maier, A. B., Dec 2012, In : American Journal of Medicine. 125, 12

Research output: Contribution to JournalArticleAcademicpeer-review

Proton magnetic resonance spectroscopy shows lower intramyocellular lipid accumulation in middle-aged subjects predisposed to familial longevity

Wijsman, C. A., van Opstal, A. M., Kan, H. E., Maier, A. B., Westendorp, R. G. J., Slagboom, P. E., Webb, A. G., Mooijaart, S. P. & van Heemst, D., Feb 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 3, p. 344-348 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Responsiveness of the innate immune system and glucose concentrations in the oldest old

Wijsman, C. A., Mooijaart, S. P., Westendorp, R. G. J. & Maier, A. B., Aug 2012, In : Age. 34, 4, p. 983-986 4 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Risk factors for failure to return to the pre-fracture place of residence after hip fracture: A prospective longitudinal study of 444 patients

Vochteloo, A. J. H., Van Vliet-Koppert, S. T., Maier, A. B., Tuinebreijer, W. E., Röling, M. L., De Vries, M. R., Bloem, R. M., Nelissen, R. G. H. H. & Pilot, P., Jun 2012, In : Archives of Orthopaedic and Trauma Surgery. 132, 6, p. 823-830 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Serum triiodothyronine levels and inflammatory cytokine production capacity

Rozing, M. P., Westendorp, R. G. J., Maier, A. B., Wijsman, C. A., Frölich, M., De Craen, A. J. M. & Van Heemst, D., Feb 2012, In : Age. 34, 1, p. 195-201 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Spinal reflex properties in the long term after stroke

Groenewegen, J. S., de Groot, J. H., Schouten, A. C., Maier, A. B., Arendzen, J. H. & Meskers, C. G. M., Apr 2012, In : Journal of Electromyography and Kinesiology. 22, 2, p. 234-242 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Temporal relationship between handgrip strength and cognitive performance in oldest old people

Taekema, D. G., Ling, C. H. Y., Kurrle, S. E., Cameron, I. D., Meskers, C. G. M., Blauw, G. J., Westendorp, R. G. J., De craen, A. J. M. & Maier, A. B., Jul 2012, In : Age and Ageing. 41, 4, p. 506-512 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

The effect of chronological age on the inflammatory response of human fibroblasts

Wolf, J., Weinberger, B., Arnold, C. R., Maier, A. B., Westendorp, R. G. J. & Grubeck-Loebenstein, B., Sep 2012, In : Experimental Gerontology. 47, 9, p. 749-753 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The number of p16INK4a positive cells in human skin reflects biological age

Waaijer, M. E. C., Parish, W. E., Strongitharm, B. H., van Heemst, D., Slagboom, P. E., de Craen, A. J. M., Sedivy, J. M., Westendorp, R. G. J., Gunn, D. A. & Maier, A. B., Aug 2012, In : Aging Cell. 11, 4, p. 722-725 4 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Total joint replacement in the past does not relate to a deteriorated functional level and health status in the oldest old

Verra, W. C., De Craen, A. J. M., Jaspars, C. C. M. M., Gussekloo, J., Blauw, G. J., Westendorp, R. G. J., Maier, A. B. & Nelissen, R. G. H. H., 2012, In : Journal of Aging Research. 2012, 7 p., 968389.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Uitgebreide geriatrische assessment

Translated title of the contribution: Comprehensive geriatric assessment: Unfeasible and undesirableBlauw, G. J. & Maier, A. B., Jan 2012, In : Nederlands Tijdschrift voor Geneeskunde. 156, 1, A4010.

Research output: Contribution to JournalComment / Letter to the editorAcademic

2011

Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population

Ling, C. H. Y., de Craen, A. J. M., Slagboom, P. E., Gunn, D. A., Stokkel, M. P. M., Westendorp, R. G. J. & Maier, A. B., Oct 2011, In : Clinical Nutrition. 30, 5, p. 610-615 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

An unopposed proinflammatory response is beneficial for survival in the oldest old. Results of the Leiden 85-plus study

Wijsman, C. A., Maier, A. B., De Craen, A. J. M., Van Den Biggelaar, A. H. J. & Westendorp, R. G. J., Apr 2011, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 66 A, 4, p. 393-399 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Circulating levels of IGF1 are associated with muscle strength in middle-aged- and oldest-old women

Taekema, D. G., Ling, C. H. Y., Blauw, G. J., Meskers, C. G., Westendorp, R. G. J., De Craen, A. J. M. & Maier, A. B., 1 Feb 2011, In : European Journal of Endocrinology. 164, 2, p. 189-196 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

C-reactive protein and glucose regulation in familial longevity

Rozing, M. P., Mooijaart, S. P., Beekman, M., Wijsman, C. A., Maier, A. B., Bartke, A., Westendorp, R. G. J., Slagboom, E. P. & Van Heemst, D., Dec 2011, In : Age. 33, 4, p. 623-630 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Functional interplay between mitochondrial and proteasome activity in skin aging

Kozie, R., Greussing, R., Maier, A. B., Declercq, L. & Jansen-Dürr, P., Mar 2011, In : Journal of Investigative Dermatology. 131, 3, p. 594-603 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access