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  • A.H.M. Willemsen
2020

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Beekman, A. F. T., Jansen, R., Milaneschi, Y., Peyrot, W. J., Smit, J. H., W J H Penninx, B. & Posthuma, D., 16 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D. & Willemsen, G., Mar 2020, In : Biological Psychiatry. 87, 5, p. 419-430 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

Li, C., Stoma, S., Lotta, L. A., Warner, S., Albrecht, E., Allione, A., Arp, P. P., Broer, L., Buxton, J. L., Da Silva Couto Alves, A., Deelen, J., Fedko, I. O., Gordon, S. D., Jiang, T., Karlsson, R., Kerrison, N., Loe, T. K., Mangino, M., Milaneschi, Y., Miraglio, B. & 76 others, Pervjakova, N., Russo, A., Surakka, I., van der Spek, A., Verhoeven, J. E., Amin, N., Beekman, M., Blakemore, A. I., Canzian, F., Hamby, S. E., Hottenga, J-J., Jones, P. D., Jousilahti, P., Mägi, R., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Perola, M., Pietiläinen, K. H., Salomaa, V., Sillanpää, E., Suchiman, H. E., van Heemst, D., Willemsen, G., Agudo, A., Boeing, H., Boomsma, D. I., Chirlaque, M-D., Fagherazzi, G., Ferrari, P., Franks, P., Gieger, C., Eriksson, J. G., Gunter, M., Hägg, S., Hovatta, I., Imaz, L., Kaprio, J., Kaaks, R., Key, T., Krogh, V., Martin, N. G., Melander, O., Metspalu, A., Moreno, C., Onland-Moret, N. C., Nilsson, P., Ong, K. K., Overvad, K., Palli, D., Panico, S., Pedersen, N. L., Penninx, B. W. J. H., Quirós, J. R., Jarvelin, M. R., Rodríguez-Barranco, M., Scott, R. A., Severi, G., Slagboom, P. E., Spector, T. D., Tjonneland, A., Trichopoulou, A., Tumino, R., Uitterlinden, A. G., van der Schouw, Y. T., van Duijn, C. M., Weiderpass, E., Denchi, E. L., Matullo, G., Butterworth, A. S., Danesh, J., Samani, N. J., Wareham, N. J., Nelson, C. P., Langenberg, C. & Codd, V., 5 Mar 2020, In : American Journal of Human Genetics. 106, 3, p. 389-404 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Beekman, A. T. F., Jansen, R., Milaneschi, Y., Smit, J. H., W J H Penninx, B. & Posthuma, D., 23 Jan 2020, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

BBMRI Metabolomics Consortium, 7 Jan 2020, In : Nature Communications. 11, 1, p. 39 39.

Research output: Contribution to JournalArticleAcademicpeer-review

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

Liu, J., Lahousse, L., Nivard, M. G., Bot, M., Chen, L., van Klinken, J. B., Thesing, C. S., Beekman, M., van den Akker, E. B., Slieker, R. C., Waterham, E., van der Kallen, C. J. H., de Boer, I., Li-Gao, R., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L. J. M., Murad, S. D. & 29 others, Uitterlinden, A. G., Willemsen, G., Pool, R., Milaneschi, Y., van Heemst, D., Suchiman, H. E. D., Rutters, F., Elders, P. J. M., Beulens, J. W. J., van der Heijden, A. A. W. A., van Greevenbroek, M. M. J., Arts, I. C. W., Onderwater, G. L. J., van den Maagdenberg, A. M. J. M., Mook-Kanamori, D. O., Hankemeier, T., Terwindt, G. M., Stehouwer, C. D. A., Geleijnse, J. M., 't Hart, L. M., Slagboom, P. E., van Dijk, K. W., Zhernakova, A., Fu, J., Penninx, B. W. J. H., Boomsma, D. I., Demirkan, A., Stricker, B. H. C. & van Duijn, C. M., Jan 2020, In : Nature Medicine. 26, 1, p. 110-117 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Substance use: Interplay between polygenic risk and neighborhood environment

Pasman, J. A., Verweij, K. J. H., Abdellaoui, A., Hottenga, J. J., Fedko, I. O., Willemsen, G., Boomsma, D. I. & Vink, J. M., 28 Feb 2020, In : Drug and Alcohol Dependence. 209, p. 107948

Research output: Contribution to JournalArticleAcademicpeer-review

2019

A Genetic Investigation of the Well-Being Spectrum

Baselmans, B. M. L., van de Weijer, M. P., Abdellaoui, A., Vink, J. M., Hottenga, J. J., Willemsen, G., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Bartels, M., 15 May 2019, In : Behavior Genetics. 49, 3, p. 286-297 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies

Doering, S., Lichtenstein, P., Gillberg, C., Boomsma, D. I., Van Beijsterveldt, T. C. E. M., Ligthart, L., Willemsen, G., De Geus, E., Middeldorp, C. M., Bartels, M., Kuja-Halkola, R. & Lundström, S., 14 Nov 2019, In : BMC Psychiatry. 19, 1, p. 1-11 11 p., 363.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Association between rs1051730 and smoking during pregnancy in Dutch women

Mbarek, H., van Beijsterveldt, C. E. M., Hottenga, J. J., Dolan, C. V., Boomsma, D. I., Willemsen, G. & Vink, J. M., Jun 2019, In : Nicotine and Tobacco Research. 21, 6, p. 835-840 6 p., ntx267.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B., Jansen, R. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Associations between Loneliness and Personality are Mostly Driven by a Genetic Association with Neuroticism

Abdellaoui, A., Chen, H-Y., Willemsen, G., Ehli, E. A., Davies, G. E., Verweij, K. J. H., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Cacioppo, J. T., Apr 2019, In : Journal of Personality. 87, 2, p. 386-397 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

23Andme Research Team & HUNT All-In Psychiatry, Feb 2019, In : Nature Genetics. 51, 2, p. 237-244 8 p.

Research output: Contribution to JournalLetterAcademicpeer-review

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Sullivan, P., 11 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Cohabitation is associated with a greater resemblance in gut microbiota which can impact cardiometabolic and inflammatory risk

Finnicum, C. T., Beck, J. J., Dolan, C. V., Davis, C., Willemsen, G., Ehli, E. A., Boomsma, D. I., Davies, G. E. & de Geus, E. J. C., 22 Oct 2019, In : BMC Microbiology. 19, 1, p. 1-10 10 p., 230.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetic Vulnerability for Smoking and Cannabis Use: Associations With E-Cigarette and Water Pipe Use

International Cannabis Consortium, 21 May 2019, In : Nicotine and Tobacco Research. 21, 6, p. 723-730 8 p., nty150.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium, 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes

Chen, J., Loukola, A., Gillespie, N. A., Peterson, R., Jia, P., Riley, B., Maes, H., Dick, D. M., Kendler, K. S., Damaj, M. I., Miles, M. F., Zhao, Z., Li, M. D., Vink, J. M., Minica, C. C., Willemsen, G., Boomsma, D. I., Qaiser, B., Madden, P. A. F., Korhonen, T. & 26 others, Jousilahti, P., Hällfors, J., Gelernter, J., Kranzler, H. R., Sherva, R., Farrer, L., Maher, B., Vanyukov, M., Taylor, M., Ware, J. J., Munafò, M. R., Lutz, S. M., Hokanson, J. E., Gu, F., Landi, M. T., Caporaso, N. E., Hancock, D. B., Gaddis, N. C., Baker, T. B., Bierut, L. J., Johnson, E. O., Chenoweth, M., Lerman, C., Tyndale, R., Kaprio, J. & Chen, X., 11 Jul 2019, In : Nicotine and Tobacco Research.

Research output: Contribution to JournalArticleAcademicpeer-review

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23Andme Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

EGG Consortium, 1 May 2019, In : Nature Genetics. 51, 5, p. 804-814 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Küpers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C. V., Allard, C., Just, A. C., Bakulski, K. M., Holloway, J. W. & 107 others, Everson, T. M., Xu, C. J., Huang, R. C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F. I., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M. R., Bergström, A., Örtqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Håberg, S. E., Sørensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I. V., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D. I., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melén, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M. F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Davey Smith, G., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 23 Apr 2019, In : Nature Communications. 10, p. 1-11 11 p., 1893.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

van der Spek, A., Broer, L., Draisma, H. H. M., Pool, R., Albrecht, E., Beekman, M., Mangino, M., Raag, M., Nyholt, D. R., Dharuri, H. K., Codd, V., Amin, N., de Geus, E. J. C., Deelen, J., Demirkan, A., Yet, I., Fischer, K., Haller, T., Henders, A. K., Isaacs, A. & 19 others, Medland, S. E., Montgomery, G. W., Mooijaart, S. P., Strauch, K., Suchiman, H. E. D., Vaarhorst, A. A. M., van Heemst, D., Wang-Sattler, R., Whitfield, J. B., Willemsen, G., Wright, M. J., Martin, N. G., Samani, N. J., Metspalu, A., Eline Slagboom, P., Spector, T. D., Boomsma, D. I., van Duijn, C. M. & Gieger, C., 12 Aug 2019, In : Scientific Reports. 9, 1, p. 11623 11623.

Research output: Contribution to JournalArticleAcademicpeer-review

Multivariate genome-wide analyses of the well-being spectrum

BIOS Consortium, Mar 2019, In : Nature Genetics. 51, 3, p. 445-451 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Parental Education and Genetics of BMI from Infancy to Old Age: A Pooled Analysis of 29 Twin Cohorts

Silventoinen, K., Jelenkovic, A., Latvala, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Aaltonen, S., Piirtola, M., Freitas, D. L., Maia, J. A., Öncel, S. Y., Aliev, F., Ji, F., Ning, F., Pang, Z., Rebato, E., Saudino, K. J., Cutler, T. L. & 53 others, Hopper, J. L., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Cozen, W., Hwang, A. E., Mack, T. M., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Nelson, T. L., Whitfield, K. E., Sung, J., Kim, J., Lee, J., Lee, S., Llewellyn, C. H., Fisher, A., Medda, E., Nisticò, L., Toccaceli, V., Baker, L. A., Tuvblad, C., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Harris, J. R., Nilsen, T. S., Harden, K. P., Tucker-Drob, E. M., Franz, C. E., Kremen, W. S., Lyons, M. J., Lichtenstein, P., Jeong, H. U., Hur, Y. M., Boomsma, D. I., Sørensen, T. I. A. & Kaprio, J., 1 May 2019, In : Obesity. 27, 5, p. 855-865 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness

23Andme Research Team, 15 Nov 2019, In : Human Molecular Genetics. 28, 22, p. 3853-3865 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Skewed X-inactivation is common in the general female population

Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Willemsen, G. & BIOS Consortium, Mar 2019, In : European Journal of Human Genetics. 27, 3, p. 455-465 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins

Silventoinen, K., Jelenkovic, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Bogl, L. H., Freitas, D. L., Maia, J. A., Hjelmborg, J. V. B., Aaltonen, S., Piirtola, M., Latvala, A., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Ji, F., Ning, F., Pang, Z. & 118 others, Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Martin, N. G., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A., Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Tarnoki, A. D., Tarnoki, D. L., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Medda, E., Nisticò, L., Toccaceli, V., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Jeong, H-U., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Gao, W., Yu, C., Li, L., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E. M., Christensen, K., Skytthe, A., Kyvik, K. O., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Silberg, J. L., Maes, H. H., Cutler, T. L., Hopper, J. L., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Ullemar, V., Almqvist, C., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Rasmussen, F., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Harris, J. R., Sung, J., Park, H. A., Lee, J., Lee, S. J., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Llewellyn, C. H., Fisher, A., Rebato, E., Busjahn, A., Tomizawa, R., Inui, F., Watanabe, M., Honda, C., Sakai, N., Hur, Y-M., Sørensen, T. I. A., Boomsma, D. I. & Kaprio, J., Dec 2019, In : Twin research and human genetics : the official journal of the International Society for Twin Studies. 22, 6, p. 800-808 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

EArly Genetics Lifecourse Epidemiology (EAGLE) consortium & Early Growth Genetics (EGG) Consortium, Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Posthuma, D., 1 Nov 2019, In : Biological Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Twin Family Registries Worldwide: An Important Resource for Scientific Research

Hur, Y. M., Bogl, L. H., Ordoñana, J. R., Taylor, J., Hart, S. A., Tuvblad, C., Ystrom, E., Dalgård, C., Skytthe, A. & Willemsen, G., Dec 2019, In : Twin Research and Human Genetics. 22, 6, p. 427-437 11 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access

Validated inference of smoking habits from blood with a finite DNA methylation marker set

BIOS Consortium, Nov 2019, In : European Journal of Epidemiology. 34, 11, p. 1055-1074 20 p.

Research output: Contribution to JournalArticleAcademicpeer-review

WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene

The Genome of the Netherlands consortium, 10 Dec 2019, In : Scientific Reports. 9, 1, p. 1-9 9 p., 18758.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2018

An Extended Twin-Pedigree Study of Neuroticism in the Netherlands Twin Register

Boomsma, D. I., Helmer, Q., Nieuwboer, H. A., Hottenga, J. J., de Moor, M. H., van den Berg, S. M., Davies, G. E., Vink, J. M., Schouten, M. J., Dolan, C. V., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Ligthart, L. & de Geus, E. J., 1 Jan 2018, In : Behavior Genetics. 48, 1, p. 1-11

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Are Migraine and Tension-Type Headache Genetically Related? An Investigation of Twin Family Data

Ligthart, L., Huijgen, A., Willemsen, G., De Geus, E. J. C. & Boomsma, D. I., Apr 2018, In : Twin Research and Human Genetics. 21, 2, p. 112-118 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project

Jelenkovic, A., Yokoyama, Y., Sund, R., Hur, Y. M., Harris, J. R., Brandt, I., Nilsen, T. S., Ooki, S., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Saudino, K. J., Stazi, M. A., Fagnani, C., Brescianini, S., Nelson, T. L., Whitfield, K. E., Knafo-Noam, A., Mankuta, D., Abramson, L. & 30 others, Cutler, T. L., Hopper, J. L., Llewellyn, C. H., Fisher, A., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Krueger, R. F., McGue, M., Pahlen, S., Alexandra Burt, S., Klump, K. L., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Willemsen, G., Bartels, M., van Beijsterveld, C. E. M., Craig, J. M., Saffery, R., Rasmussen, F., Tynelius, P., Heikkilä, K. & Boomsma, D. I., May 2018, In : Early Human Development. 120, p. 53-60 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Bidirectional prospective associations between cardiac autonomic activity and inflammatory markers

Hu, M. X., Lamers, F., Neijts, M., Willemsen, G., De Geus, E. J. C. & Penninx, B. W. J. H., 1 Jun 2018, In : Psychosomatic Medicine. 80, 5, p. 475-482 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts

Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y. M., Ullemar, V., Almqvist, C., Magnusson, P. K., Willemsen, G., Bartels, M., Beijsterveldt, C. E. V., Bogl, L. H., Pietiläinen, K. H., Vuoksimaa, E., Ji, F., Ning, F., Pang, Z., Nelson, T. L., Whitfield, K. E., Rebato, E., Llewellyn, C. H. & 30 others, Fisher, A., Bayasgalan, G., Narandalai, D., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Stazi, M. A., Fagnani, C., Brescianini, S., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Cutler, T. L., Hopper, J. L., Krueger, R. F., McGue, M., Pahlen, S., Craig, J. M., Saffery, R., Haworth, C. M., Plomin, R., Knafo-Noam, A., Mankuta, D., Abramson, L. & Boomsma, D. I., 19 Apr 2018, In : Scientific Reports. 8, 1, 6300.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Brain reward responses to food stimuli among female monozygotic twins discordant for BMI

Doornweerd, S., De Geus, E. J., Barkhof, F., van Bloemendaal, L., Boomsma, D. I., van Dongen, J., Drent, M. L., Willemsen, G., Veltman, D. J. & IJzerman, R. G., 8 Jun 2018, In : Brain Imaging and Behavior. 12, 3, p. 718-727 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

van der Lee, S. J., Teunissen, C. E., Pool, R., Shipley, M. J., Teumer, A., Chouraki, V., Melo van Lent, D., Tynkkynen, J., Fischer, K., Hernesniemi, J., Haller, T., Singh-Manoux, A., Verhoeven, A., Willemsen, G., de Leeuw, F. A., Wagner, H., van Dongen, J., Hertel, J., Budde, K., Willems van Dijk, K. & 28 others, Weinhold, L., Ikram, M. A., Pietzner, M., Perola, M., Wagner, M., Friedrich, N., Slagboom, P. E., Scheltens, P., Yang, Q., Gertzen, R. E., Egert, S., Li, S., Hankemeier, T., van Beijsterveldt, C. E. M., Vasan, R. S., Maier, W., Peeters, C. F. W., Jörgen Grabe, H., Ramirez, A., Seshadri, S., Metspalu, A., Kivimäki, M., Salomaa, V., Demirkan, A., Boomsma, D. I., van der Flier, W. M., Amin, N. & van Duijn, C. M., Jun 2018, In : Alzheimers & Dementia. 14, 6, p. 707-722 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Cohort profile: the Geoscience and Health Cohort Consortium (GECCO) in the Netherlands

Timmermans, E. J., Lakerveld, J., Beulens, J. W. J., Boomsma, D. I., Kramer, S. E., Oosterman, M., Willemsen, G., Stam, M., Nijpels, G., Schuengel, C., Smit, J. H., Brunekreef, B., Dekkers, J. E. C., Deeg, D. J. H., Penninx, B. W. J. H. & Huisman, M., 9 Jun 2018, In : BMJ Open. 8, 6, p. 1-14 14 p., e021597.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M. & 73 others, Araya, R., Bowes, L., Burns, M. R., Byrne, E. M., Coffey, J. C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J-J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., Meyer zu Schwabedissen, H., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van der Auwera, S., Wainwright, N. W., Wang, J-C., Willemsen, G., Anderson, I. M., Arolt, V., Åslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., de Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T. C., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, D. M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M. A., Nurnberger, J. I., Breslau, N. & Bierut, L. J., 2 Jan 2018, In : Molecular Psychiatry. 23, 1, p. 133-142 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis

Ward-Caviness, C. K., Huffman, J. E., Everett, K., Germain, M., Van Dongen, J., Hill, W. D., Jhun, M. A., Brody, J. A., Ghanbari, M., Du, L., Roetker, N. S., De Vries, P. S., Waldenberger, M., Gieger, C., Wolf, P., Prokisch, H., Koenig, W., O’Donnell, C. J., Levy, D., Liu, C. & 34 others, Truong, V., Wells, P. S., Trégouët, D. A., Tang, W., Morrison, A. C., Boerwinkle, E., Wiggins, K. L., McKnight, B., Guo, X., Psaty, B. M., Sotoodenia, N., Boomsma, D. I., Willemsen, G., Ligthart, L., Deary, I. J., Zhao, W., Ware, E. B., Kardia, S. L. R., Van Meurs, J. B. J., Uitterlinden, A. G., Franco, O. H., Eriksson, P., Franco-Cereceda, A., Pankow, J. S., Johnson, A. D., Gagnon, F., Morange, P. E., De Geus, E. J. C., Starr, J. M., Smith, J. A., Dehghan, A., Björck, H. M., Smith, N. L. & Peters, A., 25 Oct 2018, In : Blood. 132, 17, p. 1842-1850 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

DNA methylation signatures of educational attainment

Dongen, J. V., Bonder, M. J., Dekkers, K. F., Nivard, M. G., Iterson, M. V., Willemsen, G., Beekman, M., Spek, A. V. D., Meurs, J. B. J. V., Franke, L., Heijmans, B. T., Duijn, C. M. V., Slagboom, P. E. & Boomsma, D. I., 23 Mar 2018, In : npj Science of Learning 2018 3:1. 3, p. 1-14 14 p., 7.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Erratum to Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

The 23andMe Research Team & AAGC collaborators, 16 Aug 2018, In : Nature Genetics. 50, 9, 1 p.

Research output: Contribution to JournalComment / Letter to the editorAcademic

Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and 'Omics' Studies

Odintsova, V. V., Willemsen, G., Dolan, C. V., Hottenga, J. J., Martin, N. G., Slagboom, P. E., Ordoñana, J. R. & Boomsma, D. I., Jun 2018, In : Twin Research and Human Genetics. 21, 3, p. 239-252 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

23Andme Research Team, Abdellaoui, A., Peyrot, W. J., Hottenga, J. J., Vinkhuyzen, A. A. E., Willemsen, G., Boomsma, D. I., van Duijn, C. M., Penninx, B., Posthuma, D. & Uitterlinden, A. G., Aug 2018, In : Nature Genetics. 50, 8, p. 1112-1121 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Oct 2018, In : Nature Genetics. 50, 10, p. 1412-1431 20 p.

Research output: Contribution to JournalArticleAcademicpeer-review