Find Research Outputs — Vrije Universiteit Amsterdam

2019

Genetisch onderzoek: Onderdeel van psychiatrische kliniek

Middeldorp, C. M., 1 Jan 2019, In : Tijdschrift voor Psychiatrie. 61, 6, p. 373-374 2 p.

Research output: Contribution to Journal › Comment / Letter to the editor › Academic

2012

Common variants at 12q15 and 12q24 are associated with infant head circumference

Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Boomsma, D. I., Hakonarson, H., Smith, G. D., Heinrich, J., Jarvelin, M-R. & Jaddoe, V. W. V., 2012, In : Nature Genetics. 44, 5, p. 532-538

Research output: Contribution to Journal › Article › Academic › peer-review

Sex Differences in Genetic Architecture of Complex Phenotypes?

Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M., van Dongen, J., van Beek, J. H. D. A., Distel, M. A., de Moor, M. H. M., Smit, D. J. A., Minica, C. C., Ligthart, L., Geels, L. M., Abdellaoui, A., Middeldorp, C. M., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Boomsma, D. I., 2012, In : PLoS ONE. 7, 12, e47371.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

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158 Downloads (Pure)

2013

Angst en depressie van de kindertijd tot in de volwassenheid

Middeldorp, C. M., 2013.

Research output: Contribution to Conference › Poster › Other research output

2015

Analysis of Behavioral and Emotional Problems in Children Highlights the Role of Genotype 9 Environment Interaction

Molenaar, D., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2015, In : Child Development. 86, 6, p. 1999-2016 18 p.

Research output: Contribution to Journal › Article › Academic › peer-review

2013

Genetic Variation at the TPH2 Gene Influences Impulsivity in Addition to Eating Disorders

Slof-Op 't Landt, M. C. T., Bartels, M., Middeldorp, C. M., van Beijsterveldt, C. E. M., Slagboom, P. E., Boomsma, D. I., van Furth, E. F. & Meulenbelt, I., 2013, In : Behavior Genetics. 43, 1, p. 24-33

Research output: Contribution to Journal › Article › Academic › peer-review

Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

Peyrot, W., Middeldorp, C. M., Jansen, R., Smit, J. H., de Geus, E. J. C., Hottenga, J. J., Willemsen, G., Vink, J. M., Virding, S., Barragan, I., Ingelman-Sundberg, M., Sim, S. C., Boomsma, D. I. & Penninx, B. W. J. H., 2013, In : Journal of Affective Disorders. 146, 1, p. 91-99

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2011

Crying Without a Cause and Being Easily Upset in Two-Year-Olds: Heritability and Predictive Power of Behavioral Problems

Groen-Blokhuis, M. M., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2011, In : Twin Research and Human Genetics. 14, 5, p. 393-400

Research output: Contribution to Journal › Article › Academic › peer-review

The Impact of Environmental Experiences on Symptoms of Anxiety and Depression Across the Life Span

Kendler, K. S., Eaves, L. J., Loken, E. K., Pedersen, N. L., Middeldorp, C. M., Reynolds, C., Boomsma, D. I., Lichtenstein, P., Silberg, J. & Gardner, C. O., 2011, In : Psychological Science. 22, 10, p. 1343-1352

Research output: Contribution to Journal › Article › Academic › peer-review

2015

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bonnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 130 others, Kalb, B., Pino-Yanes, M., Xu, C., Carstensen, L., Groen-Blokhuis, M. M., Venturini, C., Pennell, C. E., Barton, S. J., Levin, A. M., Curjuric, I., Bustamante, M., Kreiner-Moller, E., Lockett, G. A., Bacelis, J., Bunyavanich, S., Myers, R. A., Matanovic, A., Kumar, A., Tung, J. Y., Hirota, T., Kubo, M., McArdle, W. L., Henderson, A. J., Kemp, J. P., Zheng, J., Smith, G. D., Rueschendorf, F., Bauerfeind, A., Lee-Kirsch, M. A., Arnold, A., Homuth, G., Schmidt, C. O., Mangold, E., Cichon, S., Keil, T., Rodriguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Foelster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L. L., Grarup, N., de Jongste, J. C., Rivadeneira, F., Hofman, A., Jaddoe, V. W. V., Pasmans, S. G. M. A., Elbert, N. J., Uitterlinden, A. G., Marks, G. B., Thompson, P. J., Matheson, M. C., Robertson, C. F., Ried, J. S., Li, J., Zuo, X. B., Zheng, X. D., Yin, X. Y., Sun, L. D., McAleer, M. A., O'Regan, G. M., Fahy, C. M. R., Campbell, L. E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D. S., Feenstra, B., Geller, F., Hottenga, J. J., Middeldorp, C. M., Hysi, P., Bataille, V., Spector, T., Tiesler, C. M. T., Thiering, E., Pahukasahasram, B., Yang, J. J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C. L., Myhre, R., Nystad, W., Custovic, A., Weiss, S. T., Meyers, D. A., Soederhaell, C., Melen, E., Ober, C., Raby, B. A., Simpson, A., Jacobsson, B., Holloway, J. W., Bisgaard, H., Sunyer, J., Probst-Hensch, N. M., Williams, L. K., Godfrey, K. M., Wang, C. A., Boomsma, D. I., Melbye, M., Koppelman, G. H., Jarvis, D., McLean, W. H. I., Irvine, A. D., Zhang, X. J., Hakonarson, H., Gieger, C., Burchard, E. G., Martin, N. G., Duijts, L., Linneberg, A., Jarvelin, M., Noethen, M. M., Lau, S., Huebner, N., Lee, Y., Tamari, M., Hinds, D. A., Glass, D., Brown, S. J., Heinrich, J., Evans, D. M. & Weidinger, S., 2015, In : Nature Genetics. 47, 12, p. 1449-1456

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2018

Genetic and environmental influences on conduct and antisocial personality problems in childhood, adolescence, and adulthood

Wesseldijk, L. W., Bartels, M., Vink, J. M., van Beijsterveldt, C. E. M., Ligthart, L., Boomsma, D. I. & Middeldorp, C. M., Sep 2018, In : European Child and Adolescent Psychiatry. 27, 9, p. 1123-1132 10 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

Childhood aggression and the co-occurrence of behavioural and emotional problems: results across ages 3–16 years from multiple raters in six cohorts in the EU-ACTION project

Bartels, M., Hendriks, A., Mauri, M., Krapohl, E., Whipp, A., Bolhuis, K., Conde, L. C., Luningham, J., Fung Ip, H., Hagenbeek, F., Roetman, P., Gatej, R., Lamers, A., Nivard, M. G., van Dongen, J., Lu, Y., Middeldorp, C., van Beijsterveldt, T., Vermeiren, R., Hankemeijer, T. & 16 others, Kluft, C., Medland, S., Lundström, S., Rose, R., Pulkkinen, L., Vuoksimaa, E., Korhonen, T., Martin, N. G., Lubke, G., Finkenauer, C., Fanos, V., Tiemeier, H., Lichtenstein, P., Plomin, R., Kaprio, J. & Boomsma, D. I., Sep 2018, In : European Child and Adolescent Psychiatry. 27, 9, p. 1105-1121 17 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

Do Parental Psychiatric Symptoms Predict Outcome in Children With Psychiatric Disorders? A Naturalistic Clinical Study

Wesseldijk, L. W., Dieleman, G. C., van Steensel, F. J. A., Bleijenberg, E. J., Bartels, M., Bögels, S. M. & Middeldorp, C. M., Sep 2018, In : Journal of the American Academy of Child and Adolescent Psychiatry. 57, 9, p. 669-677.e6 15 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

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17 Downloads (Pure)

2012

Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms

Lubke, G. H., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Boomsma, D. I., 2012, In : Biological Psychiatry. 72, 8, p. 707-709

Research output: Contribution to Journal › Article › Academic › peer-review

2011

Genome-wide complex trait analysis (gcta) for complex traits including major depressive disorder and smoking

Boomsma, D. I., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Lubke, G. H., 2011.

Research output: Contribution to Conference › Poster › Other research output

2012

Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data

Brandys, M. K., Slof-Op 't Landt, M. C. T., van Elburg, A. A., Ophoff, R. A., Verduijn, W., Meulenbelt, I., Middeldorp, C. M., Boomsma, D. I., van Furth, E. F., Slagboom, P. E., Kas, M. J. H. & Adan, R. A. H., 2012, In : Psychiatric Genetics. 22, 3, p. 130-136

Research output: Contribution to Journal › Article › Academic › peer-review

2011

Birth weight in a large series of triplets

Ponsen-Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M., Vink, J. M., Haak, M. C. & Boomsma, D. I., 2011, In : BMC Pediatrics. 11, 24.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

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Influence of Candidate Genes on Attention Problems in Children: A Longitudinal Study

van Beijsterveldt, C. E. M., Middeldorp, C. M., Slof-Op 't Landt, M. C. T., Bartels, M., Hottenga, J. J., Suchiman, H. E. D., Slagboom, P. E. & Boomsma, D. I., 2011, In : Behavior Genetics. 41, 1, p. 155-164

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

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157 Downloads (Pure)

2012

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

Webb, B. T., Guo, A. Y., Maher, B. S., Zhao, Z., van den Oord, E. J., Kendler, K. S., Riley, B. P., Gillespie, N. A., Prescott, C. A., Middeldorp, C. M., Willemsen, G., de Geus, E. J. C., Hottenga, J. J., Boomsma, D. I., Slagboom, P. E., Wray, N. R., Montgomery, G. W., Martin, N. G., Wright, M. J., Heath, A. C. & 15 others, Madden, P. A. F., Gelernter, J., Knowles, J. A., Hamilton, S. P., Weissman, M. M., Fyer, A. J., Huezo-Diaz, P., McGuffin, P., Farmer, A., Craig, I. W., Lewis, C., Sham, P., Crowe, R. R., Flint, J. & Hettema, J. M., 2012, In : European Journal of Human Genetics. 20, 10, p. 1078-1084

Research output: Contribution to Journal › Article › Academic › peer-review

2011

Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: A genetic analysis of comorbidity

Distel, M. A., Carlier, A., Middeldorp, C. M., Derom, C. A., Lubke, G. H. & Boomsma, D. I., 2011, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156, 7, p. 817-825

Research output: Contribution to Journal › Article › Academic › peer-review

2013

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth pubertal timing and childhood adiposity

Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., Groen-Blokhuis, M. M., Kreiner-Møller, E., Marinelli, M., Holst, C., Leinonen, J. T., Perry, J. R., Surakka, I., Pietilainen, O. P., Kettunen, J., Anttila, V. & 269 others, Kaakinen, M., Sovio, U., Pouta, A., Das, S., Lagou, V., Power, C., Prokopenko, I., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Palotie, A., Kajantie, E., Osmond, C., Lehtimäki, T., Viikari, J. S., Kähönen, M., Warrington, N. M., Lye, S. J., Palmer, L. J., Tiesler, C. M. T., Flexeder, C., Montgomery, G. W., Medland, S. E., Hofman, A., Hakonarson, H., Guxens, M., Bartels, M., Salomaa, V., Adair, L. S., Atalay, M., van Beijsterveldt, C. E. M., Bergen, N., Benke, K. S., Charoen, P., Coin, L., Cooper, C., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Feenstra, B., Frayling, T. M., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M. W., Goh, L. K., Hattersley, A. T., Haworth, C. M., Hadley, D., Hedebrand, J., Hinney, A., Hirschhorn, J. N., Hocher, B., Holloway, J. W., Hottenga, J. J., Horikoshi, M., Iñiguez, C., Järvelin, M. R., Kilpeläinen, T. O., Kirin, M., Kowgier, M., Lakka, H. M., Lakka, T. A., Lange, L. A., Lawlor, D. A., Lewin, A., Lindgren, C. M., Lindi, V., Maggi, R., Marsh, J., Melbye, M., Middeldorp, C. M., Millwood, I., Mohlke, K. L., Mook-Kanamori, D. O., Murray, J. C., Nivard, M. G., Nohr, E. A., Ntalla, I., Oken, E., Ong, K. K., O'Reilly, P. F., Panoutsopoulou, K., Pararajasingham, J., Pearson, E. R., Price, T. S., Rodriguez, A., Salem, R. M., Saw, S. M., Scherag, A., Sebert, S., Siitonen, N., Simell, O., Strachan, D. P., Sunyer, J., Teo, Y. Y., Uitterlinden, A. G., Valcárcel, B., White, S., Widén, E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zeggini, E., Elks, C. E., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Gudbjartsson, D. F., Esko, T., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K. E., Smith, E. N., Ulivi, S., Warrington, M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Coviello, A. D., d'Adamo, P., de Faire, U., de Geus, E. J. C., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hu, F. B., Illig, T., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., McArdle, W. L., Mooser, V., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Porcu, E., Rafnar, T., Rice, J. P., Rivadeneira, F., Rudan, I., Sala, C., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V., Shuldiner, A. R., Soranzo, N., Srinivasan, S. R., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D., Weedon, M. N., Wichmann, H. E., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Murray, A., Murabito, J. M., Kaprio, J., Sørensen, T. I. A., Ballester, F., Bisgaard, H., Boomsma, D. I., Koppelman, G. H., Grant, S. F., Jaddoe, V. W., Martin, N. G., Heinrich, J., Raitakari, O. T., Eriksson, J. G., Smith, G. D., Hyppönen, E., McCarthy, M. I. & Ripatti, S., 2013, In : Human Molecular Genetics. 22, 13, p. 2735-2747

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

Serotonin Transporter Gene: Will Epigenetics Prove Less Depressing Than Genetics?

de Geus, E. J. C. & Middeldorp, C. M., 2013, In : Psychosomatic Medicine. 75, 6, p. 520-522

Research output: Contribution to Journal › Article › Academic › peer-review

2015

Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Maier, R., Moser, G., Chen, G. B., Ripke, S., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Middeldorp, C. M., Willemsen, G., Coryell, W. H., Potash, J. B., Scheftner, W. A., Shi, J., Weissmann, M. M., Hultman, C. M., Landén, M., Levinson, D. F., Kendler, K. S., Smoller, J. W., Wray, N. R. & 1 others, Lee, S. H., 2015, In : American Journal of Human Genetics. 96, 2, p. 283-294 12 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2011

Association study in eating disorders: TPH2 associates with anorexia nervosa and self induced vomiting

Slof-Op 't Landt, M. C. T., Meulenbelt, I., Bartels, M., Suchiman, E., Middeldorp, C. M., Houwing-Duistermaat, J. J., van Trier, J., Onkenhout, E. J., Vink, J. M., van Beijsterveldt, C. E. M., Brandys, M. K., Sanders, N., Zipfel, S., Herzog, W., Herpertz-Dahlmann, B., Klampfl, K., Fleischhaker, C., Zeeck, A., Zwaan, M., Herpertz, S. & 9 others, Ehrlich, S., van Elburg, A. A., Adan, R. A. H., Scherag, S., Hinney, A., Hebebrand, J., Boomsma, D. I., van Furth, E. F. & Slagboom, P. E., 2011, In : Genes, Brain and Behavior. 10, 2, p. 236-243

Research output: Contribution to Journal › Article › Academic › peer-review

2013

Genetic and Environmental Stability in Attention Problems Across the Lifespan: Evidence From the Netherlands Twin Register

Kan, K. J., Dolan, C. V., Nivard, M. G., Middeldorp, C. M., van Beijsterveldt, C. E. M., Willemsen, G. & Boomsma, D. I., 2013, In : Journal of the American Academy of Child and Adolescent Psychiatry. 52, 1, p. 12-25

Research output: Contribution to Journal › Article › Academic › peer-review

The Young Netherlands Twin Register (YNTR): Longitudinal Twin and Family Studies in Over 70,000 Children

van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Franic, S., Hudziak, J. J., Lamb, D. J., Huppertz, C., de Zeeuw, E. L., Nivard, M. G., Schutte, N. M., Swagerman, S. C., Glasner, T. J., van Fulpen, M. J., Brouwer, C. D., Stroet, T. M., Nowotny, D., Ehli, E. A., Davies, G. E., Scheet, P., Orlebeke, J. F., Kan, K. J. & 6 others, Smit, D. J. A., Dolan, C. V., Middeldorp, C. M., de Geus, E. J. C., Bartels, M. & Boomsma, D. I., 2013, In : Twin Research and Human Genetics. 16, 1, p. 252-267

Research output: Contribution to Journal › Article › Academic › peer-review

2015

Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height

Fedko, I. O., Hottenga, J. J., Medina-Gomez, C., Pappa, I., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Rivadeneira, F., Tiemeier, H., Swertz, M. A., Middeldorp, C. M., Bartels, M. & Boomsma, D. I., 2015, In : Behavior Genetics. 45, 5, p. 514-528 15 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

Stability in symptoms of anxiety and depression as a function of genotype and environment: a longitudinal twin study from ages 3 to 63 years

Nivard, M. G., Dolan, C. V., Kendler, K. S., Kan, K. J., Willemsen, G., van Beijsterveldt, C. E. M., Lindauer, R. J. L., van Beek, J. H. D. A., Geels, L. M., Bartels, M., Middeldorp, C. M. & Boomsma, D. I., 2015, In : Psychological Medicine. 45, 05, p. 1039-1049 11 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Single Nucleotide Polymorphism Heritability of Behavior Problems in Childhood: Genome-Wide Complex Trait Analysis

Pappa, I., Fedko, I. O., Mileva-Seitz, V. R., Hottenga, J. J., Bakermans-Kranenburg, M. J., Bartels, M., van Beijsterveldt, C. E. M., Jaddoe, V. W. V., Middeldorp, C. M., Rippe, R. C. A., Rivadeneira, F., Tiemeier, H., Verhulst, F. C., van IJzendoorn, M. H. & Boomsma, D. I., 2015, In : Journal of the American Academy of Child and Adolescent Psychiatry. 54, 9, p. 737-744 8 p.

Research output: Contribution to Journal › Article › Academic › peer-review

2019

Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2019, In : JAMA Psychiatry. 76, 4, p. 399-408 10 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

File

4 Downloads (Pure)

2015

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

O’Dushlaine, C., Rossin, L., Lee, P. H., Duncan, L., Parikshak, N. N., Newhouse, S., Ripke, S., Neale, B. M., Purcell, S. M., Posthuma, D., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Krabbendam, A. C., Middeldorp, C. M., Penninx, B. W. J. H., Sergeant, J. A., Smit, J. H., Grootheest, G., Willemsen, G. & 2 others, Holmes, P. & Breen, G., 2015, In : Nature Neuroscience. 18, 2, p. 199-209 11 p.

Research output: Contribution to Journal › Article › Academic › peer-review

2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 350 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Buccola, N. G., Buitelaar, J. K., Bunney, W. E., Buxbaum, J. D., Byerley, W. F., Byrne, E. M., Caesar, S., Cahn, W., Cantor, R. M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Cloninger, C. R., Collier, D. A., Cook, E. H., Coon, H., Corman, B., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Crosbie, J., Cuccaro, M. L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., de Geus, E. J. C., Degenhardt, F., Djurovic, S., Donohoe, G., Doyle, A. E., Duan, J., Dudbridge, F., Duketis, E., Ebstein, R. P., Edenberg, H. J., Elia, J., Ennis, S., Etain, B., Fanous, A., Farmer, A. E., Ferrier, I. N., Flickinger, M., Fombonne, E., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Freitag, C., Friedl, M., Frisén, L., Gallagher, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Geschwind, D. H., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grice, D. E., Gross, M., Grozeva, D., Guan, W., Gurling, H., de Haan, L., Haines, J. L., Hakonarson, H., Hallmayer, J., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hoogendijk, W. J. G., Hottenga, J. J., Hultman, C. M., Hus, V., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, I., Jones, L., Tzeng, J. Y., Kähler, A. K., Kahn, R. S., Kandaswamy, R., Keller, M. C., Kennedy, J. L., Kenny, E., Kent, L., Kim, Y., Kirov, G. K., Klauck, S. M., Klei, L., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krabbendam, L., Krasucki, R., Kuntsi, J., Kwan, P., Landén, M., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Ledbetter, D. H., Lee, P. H., Lencz, T., Lesch, K. P., Levinson, D. F., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Liu, C., Lohoff, F. W., Loo, S. K., Lord, C., Lowe, J. K., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Maestrini, E., Magnusson, P. K. E., Mahon, P. B., Maier, W., Malhotra, A. K., Mane, S. M., Martin, C. L., Martin, N. G., Mattheisen, M., Matthews, K., Mattingsdal, M., McCarroll, S. A., McGhee, K. A., McGough, J. J., McGrath, P. J., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McLean, A. W., McMahon, F. J., McMahon, W. M., McQuillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Meyer, J., Middeldorp, C. M., Middleton, L., Milanova, V., Miranda, A., Monaco, A. P., Montgomery, G. W., Moran, J. L., Moreno-De Luca, D., Morken, G., Morris, D. W., Morrow, E. M., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Murtha, M., Myers, R. M., Myin-Germeys, I., Neale, M. C., Nelson, S. F., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V. L., Nolen, W. A., Nöthen, M. M., Nurnberger, J. I., Nwulia, E. A., Nyholt, DR., O'Dushlaine, C., Oades, R. D., Olincy, A., Oliveira, G., Olsen, L., Ophoff, R. A., Osby, U., Owen, M. J., Palotie, A., Parr, J. R., Paterson, A. D., Pato, C. N., Pato, M. T., Penninx, B. W. J. H., Pergadia, M. L., Pericak-Vance, M. A., Pickard, B. S., Pimm, J., Piven, J., Posthuma, D., Potash, J. B., Poustka, F., Propping, P., Puri, V., Quested, D., Quinn, E. M., Ramos-Quiroga, J. A., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Ribasés, M., Rice, J. P., Rietschel, M., Roeder, K., Roeyers, H., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Sanders, S. J., Santangelo, S., Sergeant, J. A., Schachar, R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Scherer, S. W., Schork, N. J., Schulze, T. G., Schumacher, J., Schwarz, M., Scolnick, E., Scott, L. J., Shi, J., Shilling, P. D., Shyn, S. I., Silverman, J. M., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E. J., St Clair, D., State, M., Steffens, M., Steinhausen, H. C., Strauss, J., Strohmaier, J., Stroup, T. S., Sutcliffe, J., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Todorov, A. A., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J. C. G., Grootheest, G., van Os, J., Vicente, A., Vieland, V., Vincent, J. B., Visscher, P. M., Walsh, C. A., Wassink, T. H., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Wijsman, E. M., Willemsen, G., Williams, N., Willsey, A. J., Witt, S. H., Xu, W., Young, A. H., Yu, T. W., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S., Devlin, B., Kelsoe, J., Sklar, P., Daly, M. J., O'Donovan, M. C., Craddock, N., Sullivan, P. F., Smoller, J. W., Kendler, K. S. & Wray, N. R., 2013, In : Nature Genetics. 45, 9, p. 984-994

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2015

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~ 25 000 subjects

Peyrot, W., Lee, S. H., Milaneschi, Y., Abdellaoui, A., Byrne, E. M., Esko, T., de Geus, E. J. C., Hemani, G., Hottenga, J. J., Kloiber, S., Levinson, D. F., Lucae, S., Martin, N. G., Medland, S. E., Metspalu, A., Milani, L., Noethen, M. M., Potash, J. B., Rietschel, M., Rietveld, C. A. & 9 others, Ripke, S., Shi, J., Willemsen, G., Zhu, Z., Boomsma, D. I., Wray, N. R., Posthuma, D., Middeldorp, C. M. & Penninx, B. W. J. H., 2015, In : Molecular Psychiatry. 20, 6, p. 735-743 9 p.

Research output: Contribution to Journal › Article › Academic › peer-review

2019

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Sullivan, P., 11 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2018

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 20 Dec 2018, In : PLoS ONE. 13, 12, p. 1-29 29 p., e0209160.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2011

De invloed van genen en omgeving op de ontwikkeling van angststoornissen

Middeldorp, C. M. & Cath, D. C., 2011, Handboek angststoornissen. van Balkom, A. J. L. M., Oosterbaan, D., Visser, S. & van Vliet, I. M. (eds.). Utrecht: De Tijdstroom, p. 287-302 15 p.

Research output: Chapter in Book / Report / Conference proceeding › Chapter › Academic

2013

The Val66Met polymorphism of the BDNF gene in anorexia nervosa: New data and a meta-analysis

Brandys, M. K., Kas, M. J. H., van Elburg, A. A., Ophoff, R. A., Slof-Op 't Landt, M. C. T., Middeldorp, C. M., Boomsma, D. I., van Furth, E. F., Slagboom, P. E. & Adan, R. A. H., 2013, In : World Journal of Biological Psychiatry. 14, 6, p. 441-451

Research output: Contribution to Journal › Article › Academic › peer-review

The use of longitudinal data of childhood and adolescent internalizing problems in genetic studies

Middeldorp, C. M., 2013.

Research output: Contribution to Conference › Poster › Other research output

A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems

Groen-Blokhuis, M. M., Franic, S., van Beijsterveldt, C. E. M., de Geus, E. J. C., Bartels, M., Davies, G. E., Ehli, E. A., Xiao, X., Scheet, P., Althoff, R. R., Hudziak, J. J., Middeldorp, C. M. & Boomsma, D. I., 2013, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 162, 5, p. 457-465

Research output: Contribution to Journal › Article › Academic › peer-review

A mega-analysis of genome-wide association studies for major depressive disorder

Ripke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Byrne, E. M., Blackwood, D. H., Boomsma, D. I., Cichon, S., Heath, A. C., Holsboer, F., Lucae, S., Madden, P. A., Martin, N. G., McGuffin, P., Muglia, P., Noethen, M. M., Penninx, B. W. J. H., Pergadia, M. L. & 96 others, Potash, J. B., Rietschel, M., Lin, D., Müller-Myhsok, B., Shi, J., Steinberg, S., Grabe, H. J., Lichtenstein, P., Magnusson, P., Perlis, R. H., Preisig, M., Smoller, J. W., Stefansson, K., Uher, R., Kutalik, Z., Tansey, K. E., Teumer, A., Viktorin, A., Barnes, M. R., Bettecken, T., Binder, E. B., Breuer, R., Castro, V. M., Churchill, S. E., Coryell, W. H., Craddock, N., Craig, I. W., Czamara, D., de Geus, E. J. C., Degenhardt, F., Farmer, A. E., Fava, M., Frank, J., Gainer, V. S., Gallagher, P. J., Gordon, S. D., Goryachev, S., Gross, M., Guipponi, M., Henders, A. K., Herms, S., Hickie, I. B., Hoefels, S., Hoogendijk, W. J. G., Hottenga, J. J., Iosifescu, D. V., Ising, M., Jones, I., Jones, L., Jung-Ying, T., Knowles, J. A., Kohane, I. S., Kohli, M. A., Korszun, A., Landen, M., Lawson, W. B., Lewis, G., MacIntyre, D. J., Maier, W., Mattheisen, M., McGrath, P. J., McIntosh, A., McLean, A., Middeldorp, C. M., Middleton, L., Montgomery, G. M., Murphy, S. N., Nauck, M., Nolen, W. A., Nyholt, DR., O'Donovan, M., Oskarsson, H., Pedersen, N., Scheftner, W. A., Schulz, A., Schulze, T. G., Shyn, S. I., Sigurdsson, E., Slager, S. L., Smit, J. H., Stefansson, H., Steffens, M., Thorgeirsson, T. E., Tozzi, F., Treutlein, J., Uhr, M., van den Oord, E. J., Grootheest, G., Völzke, H., Weilburg, J. B., Willemsen, G., Zitman, F. G., Neale, B., Daly, M., Levinson, D. F. & Sullivan, P. F., 2013, In : Molecular Psychiatry. 18, 4, p. 497-511

Research output: Contribution to Journal › Article › Academic › peer-review

2011

Life events and borderline personality features: the influence of gene–environment interaction and gene–environment correlation

Distel, M. A., Middeldorp, C. M., Trull, T. J., Derom, C. A., Willemsen, G. & Boomsma, D. I., 2011, In : Psychological Medicine. 41, 4, p. 849-860

Research output: Contribution to Journal › Article › Academic › peer-review

2012

Genome-Wide Association Uncovers Shared Genetic Effects Among Personality Traits and Mood States

Luciano, M., Huffman, J. E., Arias-Vasquez, A., Vinkhuyzen, A. A. E., Middeldorp, C. M., Giegling, I., Payton, A., Davies, G. E., Zgaga, L., Janzing, J. G., Ke, X. Y., Galesloot, T., Hartmann, A. M., Ollier, W., Tenesa, A., Hayward, C., Verhagen, M., Montgomery, G. W., Hottenga, J. J., Konte, B. & 24 others, Starr, J. M., Vitart, V., Vos, P. E., Madden, P. A. F., Willemsen, G., Konnerth, H., Horan, M. A., Porteous, D. J., Campbell, H., Vermeulen, S. H., Heath, A. C., Wright, A., Polasek, O., Kovacevic, S. B., Hastie, N., Franke, B., Boomsma, D. I., Martin, N. G., Rujescu, D., Wilson, J. F., Buitelaar, J., Pendleton, N., Rudan, I. & Deary, I. J., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 6, p. 684-695

Research output: Contribution to Journal › Article › Academic › peer-review

Gene–environment interaction in teacher-rated internalizing and externalizing problem behavior in 7- to 12-year-old twins

Ponsen-Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2012, In : Journal of Child Psychology and Psychiatry. 53, 8, p. 818-825

Research output: Contribution to Journal › Article › Academic › peer-review

2011

Evidence for a causal association of low birth weight and attention problems

Groen-Blokhuis, M. M., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2011, In : Journal of the American Academy of Child and Adolescent Psychiatry. 50, 12, p. 1247-1254

Research output: Contribution to Journal › Article › Academic › peer-review

2015

Genetica en psychische stoornissen op de kinderleeftijd: erfelijkheid en de zoektocht naar genen

Middeldorp, C. M., 2015, In : Tijdschrift voor Psychiatrie. 57, 12, p. 876-880 5 p.

Research output: Contribution to Journal › Article › Professional

2018

Risk factors for parental psychopathology: a study in families with children or adolescents with psychopathology

Wesseldijk, L. W., Dieleman, G. C., van Steensel, F. J. A., Bartels, M., Hudziak, J. J., Lindauer, R. J. L., Bögels, S. M. & Middeldorp, C. M., Dec 2018, In : European Child and Adolescent Psychiatry. 27, 12, p. 1575-1584 10 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2019

Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 15 Mar 2019, In : Translational Psychiatry. 9, 1, p. 1-9 9 p., 117.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

EArly Genetics Lifecourse Epidemiology (EAGLE) consortium & Early Growth Genetics (EGG) Consortium, Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300 34.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2011

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

Demirkan, A., Penninx, B. W. J. H., Hek, K., Wray, N. R., Amin, N., Aulchenko, Y. S., van Dyck, R., de Geus, E. J. C., Hofman, A., Uitterlinden, A. G., Hottenga, J. J., Nolen, W. A., Oostra, B. A., Sullivan, P. F., Willemsen, G., Zitman, F. G., Tiemeier, H., Janssens, A. C. J. W., Boomsma, D. I., van Duijn, C. M. & 1 others, Middeldorp, C. M., 2011, In : Molecular Psychiatry. 16, 7, p. 773-783

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2019

Anxiety at age 15 predicts psychiatric diagnoses and suicidal ideation in late adolescence and young adulthood: results from two longitudinal studies

Doering, S., Lichtenstein, P., Gillberg, C., Boomsma, D. I., Van Beijsterveldt, T. C. E. M., Ligthart, L., Willemsen, G., De Geus, E., Middeldorp, C. M., Bartels, M., Kuja-Halkola, R. & Lundström, S., 14 Nov 2019, In : BMC Psychiatry. 19, 1, p. 1-11 11 p., 363.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

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