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  • Anja Wilmes

A protocol for one-step differentiation of human induced pluripotent stem cells into mature podocytes

Murphy, C., Feifel, E., Jennings, P., Gstraunthaler, G. & Wilmes, A., 2019, Cell-Based Assays Using iPSCs for Drug Development and Testing. Mandenius, C. F. & Ross, J. (eds.). Humana Press Inc., p. 93-99 7 p. (Methods in Molecular Biology; vol. 1994).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae

Wilmes, A., Hanna, R., Heathcott, RW., Northcote, PT., Atkinson, PH., Bellows, DS. & Miller, JH., 2012, In : Gene. 497, p. 140 146 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq

Limonciel, A., Ates, G., Carta, G., Wilmes, A., Watzele, M., Shepard, P. J., VanSteenhouse, H. C., Seligmann, B., Yeakley, J. M., van de Water, B., Vinken, M. & Jennings, P., Aug 2018, In : Archives of Toxicology. 92, 8, p. 2517-2531 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Corrigendum: Investigation of Nrf2, AhR and ATF4 activation in toxicogenomic databases

Zgheib, E., Limonciel, A., Jiang, X., Wilmes, A., Wink, S., Van De Water, B., Kopp-Schneider, A., Bois, F. Y. & Jennings, P., 4 Jun 2019, In : Frontiers in Genetics. 10, JUN, 517.

Research output: Contribution to JournalErratumAcademic

Open Access

Differentiation of human iPSCs into functional podocytes

Rauch, C., Feifel, E., Kern, G., Murphy, C., Meier, F., Parson, W., Beilmann, M., Jennings, P., Gstraunthaler, G. & Wilmes, A., 17 Sep 2018, In : PLoS ONE. 13, 9, p. 1-18 18 p., e0203869.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Effects of the microtubule stabilizing agent peloruside A on the proteome of HL-60 cells

Wilmes, A., Rawson, P., McLauchlan, L., McLauchlan, D., Northcote, PT., Jordan, TW. & Miller, JH., 2011, In : Investigational New Drugs. 29, p. 544 553 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing

Stacey, G. N., Coecke, S., Price, A-B., Healy, L., Jennings, P., Wilmes, A., Pinset, C., Ingelman-Sundberg, M., Louisse, J., Haupt, S., Kidd, D., Robitski, A., Jahnke, H-G., Lemaitre, G. & Myatt, G., 28 Sep 2016, In : Advances in Experimental Medicine and Biology. 856, p. 259-297 39 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel

Wilmes, A., Aschauer, L., Limonciel, A., Pfaller, W. & Jennings, P., 1 Sep 2014, In : Toxicology and Applied Pharmacology. 279, 2, p. 163-72 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity

Wilmes, A., Crean, D., Aydin, S., Pfaller, W., Jennings, P. & Leonard, M. O., Apr 2011, In : Toxicology in Vitro. 25, 3, p. 613-22 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Investigation of Nrf2, AhR and ATF4 activation in toxicogenomic databases

Zgheib, E., Limonciel, A., Jiang, X., Wilmes, A., Wink, S., Van De Water, B., Kopp-Schneider, A., Bois, F. Y. & Jennings, P., 2 Oct 2018, In : Frontiers in Genetics. 9, October, p. 1-17 17 p., 429.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

In Vitro Toxicology Systems: Chapter 20: Translational Biomarkers, In Vitro and In Vivo

Wilmes, A., Limonciel, A. V. S., Leonard, M. O. & Jennings, P., 2014, Springer Protocols. Humana Press, p. 459-478 (Methods in Pharmacology and Toxicology).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademic

In Vitro Toxicology Systems: Chapter 15: Use of Induced Pluripotent Stem Cells in Drug Toxicity Screening

Rauch, C., Jennings, P. & Wilmes, A., 2014, Springer Protocols. Human Press, p. 335-350

Research output: Chapter in Book / Report / Conference proceedingChapterAcademic

In Vitro Toxicology Systems: Chapter 4: Renal cell culture

Jennings, P., Aschauer, L., Wilmes, A. & Gstraunthaler, G., 2014, Springer protocols. Humana Press, p. 79-101

Research output: Chapter in Book / Report / Conference proceedingChapterAcademic

Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes

Limonciel, A., Aschauer, L., Wilmes, A., Prajczer, S., Leonard, M. O., Pfaller, W. & Jennings, P., Dec 2011, In : Toxicology in Vitro. 25, 8, p. 1855-62 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells

Limonciel, A., Wilmes, A., Aschauer, L., Radford, R., Bloch, K. M., McMorrow, T., Pfaller, W., van Delft, J. H., Slattery, C., Ryan, M. P., Lock, E. A. & Jennings, P., Nov 2012, In : Archives of Toxicology. 86, 11, p. 1741-51 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Paclitaxel effects on the proteome of HL-60 promyelocytic leukemic cells: comparison to peloruside A

Wilmes, A., Chan, A., Rawson, P., Jordan, TW. & Miller, JH., 2012, In : Investigational New Drugs. 30, p. 121 129 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Peloruside- and laulimalide-resistant human ovarian carcinoma cells have βI-tubulin mutations and altered expression of βII- and βIII-tubulin isotypes

Kanakkanthara, A., Wilmes, A., O'Brate, A., Escuin, D., Chan, A., Gjyrezi, A., Crawford, J., Rawson, P., Kivell, B., Northcote, PT., Hamel, E., Giannakakou, P. & Miller, JH., 2011, In : Molecular Cancer Therapeutics. 10, p. 1419 1429 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

Limonciel, A., van Breda, S. G., Jiang, X., Tredwell, G. D., Wilmes, A., Aschauer, L., Siskos, A. P., Sachinidis, A., Keun, H. C., Kopp-Schneider, A., de Kok, T. M., Kleinjans, J. C. S. & Jennings, P., 2018, In : Frontiers in Genetics. 9, p. 558

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Structure-activity studies of the pelorusides: new congeners and semi-synthetic analogues

Singh, AJ., Razzak, M., Teesdale-Spittle, P., Gaitanos, TN., Wilmes, A., Paterson, I., Goodman, JM., Miller, JH. & Northcote, PT., 2011, In : Organic and Biomolecular Chemistry. 9, p. 4456 4466 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells

Wilmes, A., O'Sullivan, D., Chan, A., Chandrahasen, C., Paterson, I., Northcote, PT., La Flamme, AC. & Miller, JH., 2011, In : Cancer Chemotherapy and Pharmacology. 68, p. 117 126 p.

Research output: Contribution to JournalArticleAcademicpeer-review

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods

Krebs, A., van Vugt-Lussenburg, B. M. A., Waldmann, T., Albrecht, W., Boei, J., Ter Braak, B., Brajnik, M., Braunbeck, T., Brecklinghaus, T., Busquet, F., Dinnyes, A., Dokler, J., Dolde, X., Exner, T. E., Fisher, C., Fluri, D., Forsby, A., Hengstler, J. G., Holzer, A-K., Janstova, Z. & 25 others, Jennings, P., Kisitu, J., Kobolak, J., Kumar, M., Limonciel, A., Lundqvist, J., Mihalik, B., Moritz, W., Pallocca, G., Ulloa, A. P. C., Pastor, M., Rovida, C., Sarkans, U., Schimming, J. P., Schmidt, B. Z., Stöber, R., Strassfeld, T., van de Water, B., Wilmes, A., van der Burg, B., Verfaillie, C. M., von Hellfeld, R., Vrieling, H., Vrijenhoek, N. G. & Leist, M., 6 Jul 2020, In : Archives of Toxicology.

Research output: Contribution to JournalArticleAcademicpeer-review

Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion

Wilmes, A., Rauch, C., Carta, G., Kern, G., Meier, F., Posch, W., Wilflingseder, D., Armstrong, L., Lako, M., Beilmann, M., Gstraunthaler, G. & Jennings, P., 1 Dec 2017, In : Toxicology in Vitro. 45, p. 445-454 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model

Jennings, P., Weiland, C., Limonciel, A., Bloch, K. M., Radford, R., Aschauer, L., McMorrow, T., Wilmes, A., Pfaller, W., Ahr, H. J., Slattery, C., Lock, E. A., Ryan, M. P. & Ellinger-Ziegelbauer, H., Apr 2012, In : Archives of Toxicology. 86, 4, p. 571-89 19 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Two-stage model-free tests of synergy in drug combinations

Kelly, C., Feng, P., Wilmes, A., Kawashima, T. & Miller, J., 2012, In : Journal of biopharmaceutical statistics. 22, p. 54 71 p.

Research output: Contribution to JournalArticleAcademicpeer-review