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• Bringing third and second harmonic generation microscopy into the clinic for the assessment of fresh lung tissue

  Van Huizen, L. M. G., Seinstra, D., Dickhoff, C., Radonic, T., Bahce, I., Van Mourik, F., Annema, J. T., Daniels, J. M. A., Van Boven, W. J. P. & Groot, M. L., 22 Jul 2019, Medical Laser Applications and Laser-Tissue Interactions IX. Lilge, L. D. & Philipp, C. M. (eds.). SPIE, 110790J. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11079).

  Research output: Chapter in Book / Report / Conference proceeding › Conference contribution › Academic › peer-review

  • Second Harmonic Generation Microscopy
  • Harmonic generation
  • lungs
  • Microscopic examination
  • harmonic generations

• Excited state dynamics and catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase

  Scrutton, N. S., Groot, M. L. & Heyes, D. J., 2012, In : Physical Chemistry Chemical Physics - PCCP. 14, 25, p. 8818-8824

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Protochlorophyllide
  • Excited states
  • Oxidoreductases
  • Enzymes
  • Catalysis

• Excited state proton transfer in strongly enhanced GFP (sGFP2)

  van Oort, B. F., ter Veer, M. J. T., Groot, M. L. & van Stokkum, I. H. M., 2012, In : Physical Chemistry Chemical Physics - PCCP. 14, 25, p. 8852-8858

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Proton transfer
  • Excited states
  • enhanced green fluorescent protein
  • Green Fluorescent Proteins
  • Chromophores

• Hydrogen Bond Switching among Flavin and Amino Acids Determines the Nature of Proton-Coupled Electron Transfer in BLUF Photoreceptors

  Mathes, T., Zhu, J., van Stokkum, I. H. M., Groot, M. L., Hegemann, P. & Kennis, J. T. M., 2012, In : Journal of Physical Chemistry Letters. 3, 2, p. 203-208

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Hydrogen bonds
  • photoreceptors
  • Protons
  • Amino acids
  • amino acids

• Instant Pathology: Third and second harmonic generation microscopy for the assessment of fresh unprocessed tissue

  van Huizen, L. M. G. & Groot, M. L., Oct 2018, In : Fotonica Magazine. 43, 2, p. 7-12 6 p.

  Research output: Contribution to Journal › Article › Academic

• Photoactivation Mechanism, Timing of Protein Secondary Structure Dynamics and Carotenoid Translocation in the Orange Carotenoid Protein

  Konold, P. E., Van Stokkum, I. H. M., Muzzopappa, F., Wilson, A., Groot, M. L., Kirilovsky, D. & Kennis, J. T. M., 9 Jan 2019, In : Journal of the American Chemical Society. 141, 1, p. 520-530 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Carotenoids
  • Secondary Protein Structure
  • Proteins
  • Hydrogen bonds
  • Structural dynamics

• Quantitative comparison of 3D third harmonic generation and fluorescence microscopy images

  Zhang, Z., Kuzmin, N. V., Groot, M. L. & de Munck, J. C., Jan 2018, In : Journal of biophotonics. 11, 1, p. 1-13 13 p., e201600256.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Second Harmonic Generation Microscopy
  • Harmonic generation
  • Fluorescence microscopy
  • Fluorescence Microscopy
  • harmonic generations

• Quantitative Third Harmonic Generation Microscopy for Assessment of Glioma in Human Brain Tissue

  Zhang, Z., de Munck, J. C., Verburg, N., Rozemuller, A. J., Vreuls, W., Cakmak, P., van Huizen, L. M. G., Idema, S., Aronica, E., de Witt Hamer, P. C., Wesseling, P. & Groot, M. L., 5 Jun 2019, In : Advanced Science. 6, 11, 1900163.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Second Harmonic Generation Microscopy
  • Harmonic generation
  • Microscopic examination
  • brain
  • Glioma

• Role of PufX in Photochemical Charge Separation in the RC-LH1 Complex from Rhodobacter sphaeroides: An Ultrafast Mid-IR Pump-Probe Investigation

  Stahl, A. D., Crouch, L. I., Jones, M. R., van Stokkum, I. H. M., van Grondelle, R. & Groot, M. L., 2012, In : Journal of Physical Chemistry B. 116, 1, p. 434-444

  Research output: Contribution to Journal › Article › Academic › peer-review

• Short-Coherence Off-Axis Holographic Microscopy of Live Cell Dynamics

  Witte, S., Plauska, A. & Groot, M. L., 2012, Digital Holography and Three-Dimensional Imaging, OSA Technical Digest. Optical Society of America, p. DW3C.4

  Research output: Chapter in Book / Report / Conference proceeding › Conference contribution › Academic › peer-review

• Short-coherence off-axis holographic phase microscopy of live cell dynamics

  Witte, S., Plauska, A., Ridder, M. C., van Berge, L., Mansvelder, H. D. & Groot, M. L., 2012, In : Biomedical Optics Express. 3, 9, p. 2184-2189 5 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  File

  • Osmotic Pressure
  • HEK293 Cells
  • Cell Size
  • Microscopy
  • Lasers
  145 Downloads (Pure)

• Spectroscopic characterization of the first ultrafast catalytic intermediate in protochlorophyllide oxidoreductase

  Sytina, O., van Stokkum, I. H. M., Heyes, D. J., Hunter, C. N. & Groot, M. L., 2012, In : Physical Chemistry Chemical Physics - PCCP. 14, 2, p. 616-625

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Protochlorophyllide
  • chlorophyllide a
  • protochlorophyllide reductase
  • Oxidoreductases
  • chlorophyll a'

• Tensor regularized total variation for denoising of third harmonic generation images of brain tumors

  Zhang, Z., Groot, M. L. & de Munck, J. C., 1 Jan 2019, In : Journal of biophotonics. 12, 1, p. 1-13 13 p., e201800129.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Harmonic generation
  • Tumors
  • Tensors
  • tumors
  • brain

• Third-Harmonic Generation Microscopy For Label-Free Brain Imaging

  Witte, S., Kuzmin, N. V., Negrean, A., Lodder, J. C., Testa-Silva, G., de Kock, C. P. J., Mansvelder, H. D. & Groot, M. L., 2012, Biomedical Optics, OSA Technical Digest. Optical Society of America, p. BSu4B.4

  Research output: Chapter in Book / Report / Conference proceeding › Conference contribution › Academic › peer-review

• Ultrafast mid-infrared spectroscopy by chirped pulse upconversion in 1800-1000cm(-1) region

  Zhu, J., Mathes, T., Stahl, A. D., Kennis, J. T. M. & Groot, M. L., 2012, In : Optics Express. 20, 10, p. 10562-10571 10 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  File

  • infrared spectroscopy
  • pulses
  • pumps
  • broadband
  • probes
  316 Downloads (Pure)