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2012
Derivatization of the tricarboxylic acid cycle intermediates and analysis by online solid-phase extraction–liquid chromatography–mass spectrometry with positive-ion electrospray ionization
Kloos, D., Derks, R. J. E., Wijtmans, M., Lingeman, H., Mayboroda, O. A., Deelder, A. M., Niessen, W. M. A. & Giera, M., 2012, In : Journal of Chromatography A. 1232, p. 19-26Research output: Contribution to Journal › Article › Academic › peer-review
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Development of a profiling strategy for metabolic mixtures by combining chromatography and mass spectrometry with cell-based GPCR signaling.
Nijmeijer, S., Vischer, H. F., Rudebeck, A. F., Fleurbaaij, F., Falck, D., Leurs, R., Niessen, W. M. A. & Kool, J., 2012, In : Journal of Biomolecular Screening. 17, p. 1329-1338Research output: Contribution to Journal › Article › Academic › peer-review
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Fragmentation of toxicologically relevant drugs in negative-ion liquid chromatography – tandem mass spectrometry
Niessen, W. M. A., 2012, In : Mass Spectrometry Reviews. 31, p. 626-665Research output: Contribution to Journal › Article › Academic › peer-review
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High-resolution metabolic profiling towards G-protein coupled receptors: rapid and comprehensive screening of histamine H4 receptor ligands
Kool, J., Rudebeck, A. F., Fleurbaaij, F., Nijmeijer, S., Falck, D., Smits, R. A., Vischer, H. F., Leurs, R. & Niessen, W. M. A., 2012, In : Journal of Chromatography A. 1259, p. 213-220Research output: Contribution to Journal › Article › Academic › peer-review
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LC–MS systems for quantitative bioanalysis
van Dongen, W. D. & Niessen, W. M. A., 2012, In : Bioanalysis. 4, p. 2391-2399Research output: Contribution to Journal › Article › Academic › peer-review
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On-line electrochemistry-bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors.
Falck, D., de Vlieger, J. S. B., Giera, M., Honing, M., Irth, H., Niessen, W. M. A. & Kool, J., 2012, In : Analytical and Bioanalytical Chemistry. 403, p. 367-375Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Recent advancements in the LC- and GC-based analysis of malondialdehyde (MDA) – a brief overview.
Giera, M., Lingeman, H. & Niessen, W. M. A., 2012, In : Chromatographia. 75, p. 433-440Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
2015
Amino acid analysis using chromatography–mass spectrometry: An inter platform comparison study
Krumpochova, P., Bruyneel, B., Molenaar, D., Koukou, A., Wuhrer, M., Niessen, W. M. A. & Giera, M. A., 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 114, p. 398-407Research output: Contribution to Journal › Article › Academic › peer-review
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At-line coupling of LC-MS to bioaffinity and selectivity assessment for metabolic profiling of ligands towards chemokine receptors CXCR1 and CXCR2
Mladic, M., Scholten, D. J., Niessen, W. M. A., Somsen, G. W., Smit, M. J. & Kool, J., 2015, In : Journal of Chromatography B. 1002, p. 42-53 12 p.Research output: Contribution to Journal › Article › Academic › peer-review
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Identification of novel bioactives on the alpha-7-nAChR using an at-line cellular bioassay after nanofractionation
Otvos, R. A., Mladic, M., Alpizar, G. A., Niessen, W. M. A., Somsen, G. W., Smit, A. B. & Kool, J., Sep 2015, In : European Neuropsychopharmacology. 25, p. S244-S245Research output: Contribution to Journal › Article › Academic › peer-review
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Metabolic profiling of ligands for the chemokine receptor CXCR3 by liquid chromatography-mass spectrometry coupled to bioaffinity assessment
Mladic, M., Scholten, D. J., Wijtmans, M., Falck, D., Leurs, R., Niessen, W. M. A., Smit, M. J. & Kool, J., Sep 2015, In : Analytical and Bioanalytical Chemistry. 407, 23, p. 7067-81 15 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Solution-phase electrochemistry-nuclear magnetic resonance of small organic molecules
Falck, D. & Niessen, W. M. A., 2015, In : TrAC. Trends in Analytical Chemistry. 70, p. 31-39Research output: Contribution to Journal › Article › Academic › peer-review
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2016
At-line cellular screening methodology for identification of bioactives in mixtures targeting the alpha7-n AChR.
Ötvös, R. A., Mladic, M., Arias-Alpizar, G., Niessen, W. M. A., Somsen, G. W., Smit, A. B. & Kool, J., 2016, In : Journal of Biomolecular Screening. 21, p. 459-467Research output: Contribution to Journal › Article › Academic › peer-review
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At-line nanofractionation with parallel mass spectrometry and bioactivity assessment for the rapid screening of thrombin and factor Xa inhibitors in snake vemoms.
Mladic, M., Zietek, B. M., Krishnamoorthy Iyer, J., Hermarij, P., Niessen, W. M. A., Somsen, G. W., Kini, R. M. & Kool, J., 2016, In : Toxicon. 110, p. 79-89Research output: Contribution to Journal › Article › Academic › peer-review
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Development of an online cell-based bioactivity screening method by couplling liquid chromatography in flow cytometry with parallel mass spectrometry.
Ötvös, R. A., van Nierop, P., Niessen, W. M. A., Manjunatha Kini, R., Somsen, G. W., Smit, A. B. & Kool, J., 2016, In : Analytical Chemistry. 88, p. 4825-4832Research output: Contribution to Journal › Article › Academic › peer-review
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On-line coupling of surface plasmon resonance optical sensing to size-exclusion chromatography for affinity assessment of antibody samples.
Lakayan, D., Haselberg, R., Niessen, W. M. A., Somsen, G. W. & Kool, J., 2016, In : Journal of Chromatography A. 1452, p. 81-88Research output: Contribution to Journal › Article › Academic › peer-review
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2020
Analytics for bioactivity profiling of complex mixtures with a focus on venoms
Mladic, M., Niessen, W. M. A., Somsen, G. W. & Kool, J., 1 Jan 2020, Snake and spider toxins: methods and protocols. Humana Press Inc., p. 27-49 23 p. (Methods in Molecular Biology; vol. 2068).Research output: Chapter in Book / Report / Conference proceeding › Chapter › Academic › peer-review