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Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015

Author

  • W.M.A. Niessen
Article

Amino acid analysis using chromatography–mass spectrometry: An inter platform comparison study

Krumpochova, P., Bruyneel, B., Molenaar, D., Koukou, A., Wuhrer, M., Niessen, W. M. A. & Giera, M. A., 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 114, p. 398-407

Research output: Contribution to JournalArticleAcademicpeer-review

At-line cellular screening methodology for identification of bioactives in mixtures targeting the alpha7-n AChR.

Ötvös, R. A., Mladic, M., Arias-Alpizar, G., Niessen, W. M. A., Somsen, G. W., Smit, A. B. & Kool, J., 2016, In : Journal of Biomolecular Screening. 21, p. 459-467

Research output: Contribution to JournalArticleAcademicpeer-review

At-line nanofractionation with parallel mass spectrometry and bioactivity assessment for the rapid screening of thrombin and factor Xa inhibitors in snake vemoms.

Mladic, M., Zietek, B. M., Krishnamoorthy Iyer, J., Hermarij, P., Niessen, W. M. A., Somsen, G. W., Kini, R. M. & Kool, J., 2016, In : Toxicon. 110, p. 79-89

Research output: Contribution to JournalArticleAcademicpeer-review

Development of an online cell-based bioactivity screening method by couplling liquid chromatography in flow cytometry with parallel mass spectrometry.

Ötvös, R. A., van Nierop, P., Niessen, W. M. A., Manjunatha Kini, R., Somsen, G. W., Smit, A. B. & Kool, J., 2016, In : Analytical Chemistry. 88, p. 4825-4832

Research output: Contribution to JournalArticleAcademicpeer-review

Identification of novel bioactives on the alpha-7-nAChR using an at-line cellular bioassay after nanofractionation

Otvos, R. A., Mladic, M., Alpizar, G. A., Niessen, W. M. A., Somsen, G. W., Smit, A. B. & Kool, J., Sep 2015, In : European Neuropsychopharmacology. 25, p. S244-S245

Research output: Contribution to JournalArticleAcademicpeer-review

LC–MS/MS assay for assessing medical adherence in patients under warfarin maintenance therapy

Farouk, F., Nabhan, S., Niessen, W. M. A. & Azzazy, H. M. E., 1 Sep 2018, In : Microchemical Journal. 141, p. 135-140 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Metabolic profiling of ligands for the chemokine receptor CXCR3 by liquid chromatography-mass spectrometry coupled to bioaffinity assessment

Mladic, M., Scholten, D. J., Wijtmans, M., Falck, D., Leurs, R., Niessen, W. M. A., Smit, M. J. & Kool, J., Sep 2015, In : Analytical and Bioanalytical Chemistry. 407, 23, p. 7067-81 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Nanofractionation Platform with Parallel Mass Spectrometry for Identification of CYP1A2 Inhibitors in Metabolic Mixtures

Zietek, B. M., Mladic, M., Bruyneel, B., Niessen, W. M. A., Honing, M., Somsen, G. W. & Kool, J., Mar 2018, In : SLAS Discovery. 23, 3, p. 283-293 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling

Slagboom, J., Otvos, R. A., Cardoso, F. C., Iyer, J., Visser, J. C., van Doodewaerd, B. R., McCleary, R. J. R., Niessen, W. M. A., Somsen, G. W., Lewis, R. J., Kini, R. M., Smit, A. B., Casewell, N. R. & Kool, J., 15 Jun 2018, In : Toxicon. 148, p. 213-222 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Rapid screening and identification of ACE inhibitors in snake venoms using at-line nanofractionation LC-MS

Mladic, M., de Waal, T., Burggraaff, L., Slagboom, J., Somsen, G. W., Niessen, W. M. A., Kini, R. M. & Kool, J., Oct 2017, In : Analytical and Bioanalytical Chemistry. 409, 25, p. 5987-5997 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Solution-phase electrochemistry-nuclear magnetic resonance of small organic molecules

Falck, D. & Niessen, W. M. A., 2015, In : TrAC. Trends in Analytical Chemistry. 70, p. 31-39

Research output: Contribution to JournalArticleAcademicpeer-review

Chapter

Analytics for bioactivity profiling of complex mixtures with a focus on venoms

Mladic, M., Niessen, W. M. A., Somsen, G. W. & Kool, J., 1 Jan 2020, Snake and spider toxins: methods and protocols. Humana Press Inc., p. 27-49 23 p. (Methods in Molecular Biology; vol. 2068).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review