A Combined Toxicokinetics and Toxicodynamics Approach to Assess the Effect of Porewater Composition on Cadmium Bioavailability to Folsomia Candida

M.M. Ardestani; F. Oduber; C.A.M. van Gestel

doi:10.1002/etc.2585

A Combined Toxicokinetics and Toxicodynamics Approach to Assess the Effect of Porewater Composition on Cadmium Bioavailability to Folsomia Candida

M.M. Ardestani, F. Oduber, C.A.M. van Gestel

Animal Ecology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

The aim of the present study was to improve our understanding of cadmium bioavailability by linking toxicokinetics and toxicodynamics. The springtail Folsomia candida was exposed to different cadmium concentrations in solutions embedded in inert quartz sand. Survival and cadmium uptake in the animals were followed for 21 d. After 10 d, some animals were transferred to clean medium to assess cadmium elimination. Using a first-order one-compartment model, an overall uptake rate constant (k

Original language	English
Pages (from-to)	1570-1577
Journal	Environmental Toxicology and Chemistry
Volume	33
Issue number	7
Early online date	21 Mar 2014
DOIs	https://doi.org/10.1002/etc.2585
Publication status	Published - 2014

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abstract = "The aim of the present study was to improve our understanding of cadmium bioavailability by linking toxicokinetics and toxicodynamics. The springtail Folsomia candida was exposed to different cadmium concentrations in solutions embedded in inert quartz sand. Survival and cadmium uptake in the animals were followed for 21 d. After 10 d, some animals were transferred to clean medium to assess cadmium elimination. Using a first-order one-compartment model, an overall uptake rate constant (k",

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