A Combined Toxicokinetics and Toxicodynamics Approach to Assess the Effect of Porewater Composition on Cadmium Bioavailability to Folsomia Candida

M.M. Ardestani, F. Oduber, C.A.M. van Gestel

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

The aim of the present study was to improve our understanding of cadmium bioavailability by linking toxicokinetics and toxicodynamics. The springtail Folsomia candida was exposed to different cadmium concentrations in solutions embedded in inert quartz sand. Survival and cadmium uptake in the animals were followed for 21 d. After 10 d, some animals were transferred to clean medium to assess cadmium elimination. Using a first-order one-compartment model, an overall uptake rate constant (k
Original languageEnglish
Pages (from-to)1570-1577
JournalEnvironmental Toxicology and Chemistry
Volume33
Issue number7
Early online date21 Mar 2014
DOIs
Publication statusPublished - 2014

Fingerprint

Candida
Cadmium
Biological Availability
bioavailability
porewater
cadmium
Chemical analysis
Animals
Quartz
animal
Rate constants
Sand
quartz
sand
Toxicokinetics
effect

Cite this

@article{f527bce8e5fc42e385cee626e1038394,
title = "A Combined Toxicokinetics and Toxicodynamics Approach to Assess the Effect of Porewater Composition on Cadmium Bioavailability to Folsomia Candida",
abstract = "The aim of the present study was to improve our understanding of cadmium bioavailability by linking toxicokinetics and toxicodynamics. The springtail Folsomia candida was exposed to different cadmium concentrations in solutions embedded in inert quartz sand. Survival and cadmium uptake in the animals were followed for 21 d. After 10 d, some animals were transferred to clean medium to assess cadmium elimination. Using a first-order one-compartment model, an overall uptake rate constant (k",
author = "M.M. Ardestani and F. Oduber and {van Gestel}, C.A.M.",
year = "2014",
doi = "10.1002/etc.2585",
language = "English",
volume = "33",
pages = "1570--1577",
journal = "Environmental Toxicology and Chemistry",
issn = "0730-7268",
publisher = "John Wiley and Sons Ltd",
number = "7",

}

A Combined Toxicokinetics and Toxicodynamics Approach to Assess the Effect of Porewater Composition on Cadmium Bioavailability to Folsomia Candida. / Ardestani, M.M.; Oduber, F.; van Gestel, C.A.M.

In: Environmental Toxicology and Chemistry, Vol. 33, No. 7, 2014, p. 1570-1577.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - A Combined Toxicokinetics and Toxicodynamics Approach to Assess the Effect of Porewater Composition on Cadmium Bioavailability to Folsomia Candida

AU - Ardestani, M.M.

AU - Oduber, F.

AU - van Gestel, C.A.M.

PY - 2014

Y1 - 2014

N2 - The aim of the present study was to improve our understanding of cadmium bioavailability by linking toxicokinetics and toxicodynamics. The springtail Folsomia candida was exposed to different cadmium concentrations in solutions embedded in inert quartz sand. Survival and cadmium uptake in the animals were followed for 21 d. After 10 d, some animals were transferred to clean medium to assess cadmium elimination. Using a first-order one-compartment model, an overall uptake rate constant (k

AB - The aim of the present study was to improve our understanding of cadmium bioavailability by linking toxicokinetics and toxicodynamics. The springtail Folsomia candida was exposed to different cadmium concentrations in solutions embedded in inert quartz sand. Survival and cadmium uptake in the animals were followed for 21 d. After 10 d, some animals were transferred to clean medium to assess cadmium elimination. Using a first-order one-compartment model, an overall uptake rate constant (k

U2 - 10.1002/etc.2585

DO - 10.1002/etc.2585

M3 - Article

VL - 33

SP - 1570

EP - 1577

JO - Environmental Toxicology and Chemistry

JF - Environmental Toxicology and Chemistry

SN - 0730-7268

IS - 7

ER -