Abstract
The brain is the central organ of stress and controls the adaptation to stressors, while it perceives what is potentially threatening and determines the behavioral and physiological responses. Post-traumatic stress disorder (PTSD) is a mental health disease in which an individual has been exposed to a traumatic event that involves actual or imminent death or serious injury, or threatens the physical integrity of the self or others. The effects on the brain caused by stress for people with PTSD are the main subject of this paper. A literature research was conducted to see how stress affects the brain and how regions of the brain are distorted by an excess of myelin, which is formed by oligodendrocytes, in people with PTSD. Network-Oriented Modeling perspective is proposed as an alternative way to address complexity. This perspective takes the concept of network and the interactions within a network as a basis for conceptualization and structuring of any complex processes. It appears myelin, and the oligodendrocytes which produce the myelin can have altering effects in the brain of patients with PTSD. The fear response is increased significantly and the forming and retrieval of memories is also disrupted. As the effect of myelin is decreased in the model, the effects are also decreased. The main purpose of this paper is providing insight into what the effects of myelin excess might be for patients with PTSD, and simulating these effects to make these insights easily accessible.
| Original language | English |
|---|---|
| Title of host publication | Artificial Intelligence and Soft Computing - 18th International Conference, ICAISC 2019, Proceedings |
| Editors | Witold Pedrycz, Ryszard Tadeusiewicz, Jacek M. Zurada, Leszek Rutkowski, Rafał Scherer, Marcin Korytkowski |
| Publisher | Springer Verlag |
| Pages | 203-215 |
| Number of pages | 13 |
| ISBN (Print) | 9783030209148 |
| DOIs | |
| Publication status | Published - 1 Jan 2019 |
| Event | 18th International Conference on Artificial Intelligence and Soft Computing, ICAISC 2019 - Zakopane, Poland Duration: 16 Jun 2019 → 20 Jun 2019 |
Publication series
| Name | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
|---|---|
| Volume | 11509 LNAI |
| ISSN (Print) | 0302-9743 |
| ISSN (Electronic) | 1611-3349 |
Conference
| Conference | 18th International Conference on Artificial Intelligence and Soft Computing, ICAISC 2019 |
|---|---|
| Country | Poland |
| City | Zakopane |
| Period | 16/06/19 → 20/06/19 |
Fingerprint
Keywords
- Myelin
- Network-Oriented Modeling
- PTSD
- Stress
Cite this
}
A computational model of myelin excess for patients with post-traumatic stress disorder. / Langbroek, Jelmer; Treur, Jan; Mohammadi Ziabari, S. Sahand.
Artificial Intelligence and Soft Computing - 18th International Conference, ICAISC 2019, Proceedings. ed. / Witold Pedrycz; Ryszard Tadeusiewicz; Jacek M. Zurada; Leszek Rutkowski; Rafał Scherer; Marcin Korytkowski. Springer Verlag, 2019. p. 203-215 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11509 LNAI).Research output: Chapter in Book / Report / Conference proceeding › Conference contribution › Academic › peer-review
TY - GEN
T1 - A computational model of myelin excess for patients with post-traumatic stress disorder
AU - Langbroek, Jelmer
AU - Treur, Jan
AU - Mohammadi Ziabari, S. Sahand
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The brain is the central organ of stress and controls the adaptation to stressors, while it perceives what is potentially threatening and determines the behavioral and physiological responses. Post-traumatic stress disorder (PTSD) is a mental health disease in which an individual has been exposed to a traumatic event that involves actual or imminent death or serious injury, or threatens the physical integrity of the self or others. The effects on the brain caused by stress for people with PTSD are the main subject of this paper. A literature research was conducted to see how stress affects the brain and how regions of the brain are distorted by an excess of myelin, which is formed by oligodendrocytes, in people with PTSD. Network-Oriented Modeling perspective is proposed as an alternative way to address complexity. This perspective takes the concept of network and the interactions within a network as a basis for conceptualization and structuring of any complex processes. It appears myelin, and the oligodendrocytes which produce the myelin can have altering effects in the brain of patients with PTSD. The fear response is increased significantly and the forming and retrieval of memories is also disrupted. As the effect of myelin is decreased in the model, the effects are also decreased. The main purpose of this paper is providing insight into what the effects of myelin excess might be for patients with PTSD, and simulating these effects to make these insights easily accessible.
AB - The brain is the central organ of stress and controls the adaptation to stressors, while it perceives what is potentially threatening and determines the behavioral and physiological responses. Post-traumatic stress disorder (PTSD) is a mental health disease in which an individual has been exposed to a traumatic event that involves actual or imminent death or serious injury, or threatens the physical integrity of the self or others. The effects on the brain caused by stress for people with PTSD are the main subject of this paper. A literature research was conducted to see how stress affects the brain and how regions of the brain are distorted by an excess of myelin, which is formed by oligodendrocytes, in people with PTSD. Network-Oriented Modeling perspective is proposed as an alternative way to address complexity. This perspective takes the concept of network and the interactions within a network as a basis for conceptualization and structuring of any complex processes. It appears myelin, and the oligodendrocytes which produce the myelin can have altering effects in the brain of patients with PTSD. The fear response is increased significantly and the forming and retrieval of memories is also disrupted. As the effect of myelin is decreased in the model, the effects are also decreased. The main purpose of this paper is providing insight into what the effects of myelin excess might be for patients with PTSD, and simulating these effects to make these insights easily accessible.
KW - Myelin
KW - Network-Oriented Modeling
KW - PTSD
KW - Stress
UR - http://www.scopus.com/inward/record.url?scp=85066760731&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85066760731&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-20915-5_19
DO - 10.1007/978-3-030-20915-5_19
M3 - Conference contribution
SN - 9783030209148
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 203
EP - 215
BT - Artificial Intelligence and Soft Computing - 18th International Conference, ICAISC 2019, Proceedings
A2 - Pedrycz, Witold
A2 - Tadeusiewicz, Ryszard
A2 - Zurada, Jacek M.
A2 - Rutkowski, Leszek
A2 - Scherer, Rafał
A2 - Korytkowski, Marcin
PB - Springer Verlag
ER -