A cyanine fluorophore with a hydrazide functionality as labelling reagent for aldehydes in liquid chromatography.

A.J.G. Mank; C. Gooijer; N.H. Velthorst; J.W. Hofstraat; M.J. Nuijens; M. Zomer

doi:10.1016/0003-2670(95)00176-Z

A cyanine fluorophore with a hydrazide functionality as labelling reagent for aldehydes in liquid chromatography.

A.J.G. Mank, C. Gooijer, N.H. Velthorst, J.W. Hofstraat, M.J. Nuijens, M. Zomer

Chemistry and Pharmaceutical Sciences

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

A new hydrazide derivative of a cyanine dye is synthesized for the chemical derivatization of aldehydes. With this red absorbing fluorophore it is possible to apply visible diode laser induced fluorescence (DIO-LIF) detection in conventional-size liquid chromatography (LC). The dye is based on CY5.3a-IA, a sulfonated dicarbocyanine with a iodoacetamido reactive group. The detection limit of n-octylaldehyde is 7 × 10

Original language	English
Pages (from-to)	311
Journal	Analytica Chimica Acta
Volume	47
DOIs	https://doi.org/10.1016/0003-2670(95)00176-Z
Publication status	Published - 1995

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10.1016/0003-2670(95)00176-Z

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title = "A cyanine fluorophore with a hydrazide functionality as labelling reagent for aldehydes in liquid chromatography.",

abstract = "A new hydrazide derivative of a cyanine dye is synthesized for the chemical derivatization of aldehydes. With this red absorbing fluorophore it is possible to apply visible diode laser induced fluorescence (DIO-LIF) detection in conventional-size liquid chromatography (LC). The dye is based on CY5.3a-IA, a sulfonated dicarbocyanine with a iodoacetamido reactive group. The detection limit of n-octylaldehyde is 7 × 10",

author = "A.J.G. Mank and C. Gooijer and N.H. Velthorst and J.W. Hofstraat and M.J. Nuijens and M. Zomer",

year = "1995",

doi = "10.1016/0003-2670(95)00176-Z",

language = "English",

volume = "47",

pages = "311",

journal = "Analytica Chimica Acta",

issn = "0003-2670",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - A cyanine fluorophore with a hydrazide functionality as labelling reagent for aldehydes in liquid chromatography.

AU - Mank, A.J.G.

AU - Gooijer, C.

AU - Velthorst, N.H.

AU - Hofstraat, J.W.

AU - Nuijens, M.J.

AU - Zomer, M.

PY - 1995

Y1 - 1995

N2 - A new hydrazide derivative of a cyanine dye is synthesized for the chemical derivatization of aldehydes. With this red absorbing fluorophore it is possible to apply visible diode laser induced fluorescence (DIO-LIF) detection in conventional-size liquid chromatography (LC). The dye is based on CY5.3a-IA, a sulfonated dicarbocyanine with a iodoacetamido reactive group. The detection limit of n-octylaldehyde is 7 × 10

AB - A new hydrazide derivative of a cyanine dye is synthesized for the chemical derivatization of aldehydes. With this red absorbing fluorophore it is possible to apply visible diode laser induced fluorescence (DIO-LIF) detection in conventional-size liquid chromatography (LC). The dye is based on CY5.3a-IA, a sulfonated dicarbocyanine with a iodoacetamido reactive group. The detection limit of n-octylaldehyde is 7 × 10

U2 - 10.1016/0003-2670(95)00176-Z

DO - 10.1016/0003-2670(95)00176-Z

M3 - Article

SN - 0003-2670

VL - 47

SP - 311

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

ER -

A cyanine fluorophore with a hydrazide functionality as labelling reagent for aldehydes in liquid chromatography.

Abstract

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