A cyanine fluorophore with a hydrazide functionality as labelling reagent for aldehydes in liquid chromatography.

A.J.G. Mank, C. Gooijer, N.H. Velthorst, J.W. Hofstraat, M.J. Nuijens, M. Zomer

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

A new hydrazide derivative of a cyanine dye is synthesized for the chemical derivatization of aldehydes. With this red absorbing fluorophore it is possible to apply visible diode laser induced fluorescence (DIO-LIF) detection in conventional-size liquid chromatography (LC). The dye is based on CY5.3a-IA, a sulfonated dicarbocyanine with a iodoacetamido reactive group. The detection limit of n-octylaldehyde is 7 × 10
Original languageEnglish
Pages (from-to)311
JournalAnalytica Chimica Acta
Volume47
DOIs
Publication statusPublished - 1995

Fingerprint Dive into the research topics of 'A cyanine fluorophore with a hydrazide functionality as labelling reagent for aldehydes in liquid chromatography.'. Together they form a unique fingerprint.

Cite this