A Dutch guideline for the treatment of scoliosis in neuromuscular disorders

M.G. Mullender, N. Blom, M. de Kleuver, J. Fock, W. Hitters, A. Horemans, C. Kalkman, J. Pruijs, R. Timmer, P. Titarsolej, N. van Haasteren, M.V. Jager, A. van Vught, B.J. van Royen

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    Abstract

    Background: Children with neuromuscular disorders with a progressive muscle weakness such as Duchenne Muscular Dystrophy and Spinal Muscular Atrophy frequently develop a progressive scoliosis. A severe scoliosis compromises respiratory function and makes sitting more difficult. Spinal surgery is considered the primary treatment option for correcting severe scoliosis in neuromuscular disorders. Surgery in this population requires a multidisciplinary approach, careful planning, dedicated surgical procedures, and specialized after care. Methods: The guideline is based on scientific evidence and expert opinions. A multidisciplinary working group representing experts from all relevant specialties performed the research. A literature search was conducted to collect scientific evidence in answer to specific questions posed by the working group. Literature was classified according to the level of evidence. Results: For most aspects of the treatment scientific evidence is scarce and only low level cohort studies were found. Nevertheless, a high degree of consensus was reached about the management of patients with scoliosis in neuromuscular disorders. This was translated into a set of recommendations, which are now officially accepted as a general guideline in the Netherlands. Conclusion: In order to optimize the treatment for scoliosis in neuromuscular disorders a Dutch guideline has been composed. This evidence-based, multidisciplinary guideline addresses conservative treatment, the preoperative, perioperative, and postoperative care of scoliosis in neuromuscular disorders. © 2008 Mullender et al; licensee BioMed Central Ltd.
    Original languageEnglish
    Pages (from-to)14
    JournalScoliosis
    Volume3
    DOIs
    Publication statusPublished - 2008

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