A generic view of classic microbial growth models.

H.A. van den Berg

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    General theoretical aspects are reviewed of models for microbial growth and endogenous metabolism. The focus is on a generic cell model with two components. Growth is represented as the increase of one of these components (the structural scaffolding or 'frame'). A novel feature of the present generic model is the explicit modelling of (partial) metabolic shutdown under conditions where maintenance requirements cannot be met. Two different approaches to mechanistic underpinnings for the classic models are outlined. The first approach is based on a bimolecular reaction between the non-permanent biomass component and the permanent biomass component. The second approach is based on cellular control systems.
    Original languageEnglish
    Pages (from-to)117-130
    Number of pages14
    JournalActa Biotheoretica
    Volume46
    DOIs
    Publication statusPublished - 1998

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