A genetic analysis of brain volumes and IQ in children

M. van Leeuwen, J.S. Peper, S.M. van den Berg, R.M. Brouwer, H.E. Hulshoff Pol, R.S. Kahn, D.I. Boomsma

Research output: Contribution to JournalArticleAcademicpeer-review


In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes. Crown Copyright © 2008.
Original languageEnglish
Pages (from-to)181-191
Issue number2
Publication statusPublished - 2009

Cohort Studies

  • Netherlands Twin Register (NTR)


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