A medicinal chemistry perspective on melting point: matched molecular pair analysis of the effects of simple descriptors on the melting point of drug-like compounds

S. Schultes, C. de Graaf, H. Berger, M. Mayer, A. Steffen, E.J.J. Haaksma, I.J.P. de Esch, R. Leurs, O. Krämer

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

The influence of simple molecular descriptors on the melting point temperature (T
Original languageEnglish
Pages (from-to)584-591
JournalMedChemComm
Volume3
DOIs
Publication statusPublished - 2012

Fingerprint

Matched-Pair Analysis
Pharmaceutical Chemistry
Transition Temperature
Freezing
Melting point
Pharmaceutical Preparations
Temperature

Cite this

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title = "A medicinal chemistry perspective on melting point: matched molecular pair analysis of the effects of simple descriptors on the melting point of drug-like compounds",
abstract = "The influence of simple molecular descriptors on the melting point temperature (T",
author = "S. Schultes and {de Graaf}, C. and H. Berger and M. Mayer and A. Steffen and E.J.J. Haaksma and {de Esch}, I.J.P. and R. Leurs and O. Kr{\"a}mer",
year = "2012",
doi = "10.1039/c2md00313a",
language = "English",
volume = "3",
pages = "584--591",
journal = "MedChemComm",
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publisher = "Royal Society of Chemistry",

}

A medicinal chemistry perspective on melting point: matched molecular pair analysis of the effects of simple descriptors on the melting point of drug-like compounds. / Schultes, S.; de Graaf, C.; Berger, H.; Mayer, M.; Steffen, A.; Haaksma, E.J.J.; de Esch, I.J.P.; Leurs, R.; Krämer, O.

In: MedChemComm, Vol. 3, 2012, p. 584-591.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - A medicinal chemistry perspective on melting point: matched molecular pair analysis of the effects of simple descriptors on the melting point of drug-like compounds

AU - Schultes, S.

AU - de Graaf, C.

AU - Berger, H.

AU - Mayer, M.

AU - Steffen, A.

AU - Haaksma, E.J.J.

AU - de Esch, I.J.P.

AU - Leurs, R.

AU - Krämer, O.

PY - 2012

Y1 - 2012

N2 - The influence of simple molecular descriptors on the melting point temperature (T

AB - The influence of simple molecular descriptors on the melting point temperature (T

U2 - 10.1039/c2md00313a

DO - 10.1039/c2md00313a

M3 - Article

VL - 3

SP - 584

EP - 591

JO - MedChemComm

JF - MedChemComm

SN - 2040-2503

ER -