A Microwave-Assisted Diastereoselective Multicomponent Reaction To Access Dibenzo[c,e]azepinones: Synthesis and Biological Evaluation

V.P. Mehta, S.G. Modha, E. Ruijter, K. van Hecke, L. van Meervelt, C. Pannecouque, J. Balzarini, R.V.A. Orru, E. van der Eycken

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

An unprecedented microwave-assisted multicomponent strategy has been elaborated for the fast, efficient, and diastereoselective generation of the dibenzo[c,e]azepinone scaffold. The generated compounds were evaluated for their bioactivity. © 2011 American Chemical Society.
Original languageEnglish
Pages (from-to)2828-2839
JournalJournal of Organic Chemistry
Volume76
Issue number8
DOIs
Publication statusPublished - 2011

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