A multicomponent synthesis of triazinane diones

B. Groenendaal, D.J. Vugts, R.F. Schmitz, F.J.J. de Kanter, E. Ruijter, M.B. Groen, R.V.A. Orru

Research output: Contribution to JournalArticleAcademicpeer-review


(Chemical Equation Presented) An efficient, one-pot synthetic protocol toward triazinane diones, a rather unexplored class of heterocyclic scaffolds combining phosphonates, nitriles, aldehydes, and isocyanates is described. The optimization of the reaction, synthesis of a small library of different triazinane diones, as well as alternative routes toward the triazinane dione scaffold are discussed. © 2008 American Chemical Society.
Original languageEnglish
Pages (from-to)719-22
JournalJournal of Organic Chemistry
Issue number2
Publication statusPublished - 2008


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