A multicomponent synthesis of triazinane diones

B. Groenendaal, D.J. Vugts, R.F. Schmitz, F.J.J. de Kanter, E. Ruijter, M.B. Groen, R.V.A. Orru

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

(Chemical Equation Presented) An efficient, one-pot synthetic protocol toward triazinane diones, a rather unexplored class of heterocyclic scaffolds combining phosphonates, nitriles, aldehydes, and isocyanates is described. The optimization of the reaction, synthesis of a small library of different triazinane diones, as well as alternative routes toward the triazinane dione scaffold are discussed. © 2008 American Chemical Society.
Original languageEnglish
Pages (from-to)719-22
JournalJournal of Organic Chemistry
Volume73
Issue number2
DOIs
Publication statusPublished - 2008

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Scaffolds
Isocyanates
Organophosphonates
Nitriles
Aldehydes

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Groenendaal, B., Vugts, D. J., Schmitz, R. F., de Kanter, F. J. J., Ruijter, E., Groen, M. B., & Orru, R. V. A. (2008). A multicomponent synthesis of triazinane diones. Journal of Organic Chemistry, 73(2), 719-22. https://doi.org/10.1021/jo701973d
Groenendaal, B. ; Vugts, D.J. ; Schmitz, R.F. ; de Kanter, F.J.J. ; Ruijter, E. ; Groen, M.B. ; Orru, R.V.A. / A multicomponent synthesis of triazinane diones. In: Journal of Organic Chemistry. 2008 ; Vol. 73, No. 2. pp. 719-22.
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Groenendaal, B, Vugts, DJ, Schmitz, RF, de Kanter, FJJ, Ruijter, E, Groen, MB & Orru, RVA 2008, 'A multicomponent synthesis of triazinane diones' Journal of Organic Chemistry, vol. 73, no. 2, pp. 719-22. https://doi.org/10.1021/jo701973d

A multicomponent synthesis of triazinane diones. / Groenendaal, B.; Vugts, D.J.; Schmitz, R.F.; de Kanter, F.J.J.; Ruijter, E.; Groen, M.B.; Orru, R.V.A.

In: Journal of Organic Chemistry, Vol. 73, No. 2, 2008, p. 719-22.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - A multicomponent synthesis of triazinane diones

AU - Groenendaal, B.

AU - Vugts, D.J.

AU - Schmitz, R.F.

AU - de Kanter, F.J.J.

AU - Ruijter, E.

AU - Groen, M.B.

AU - Orru, R.V.A.

PY - 2008

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N2 - (Chemical Equation Presented) An efficient, one-pot synthetic protocol toward triazinane diones, a rather unexplored class of heterocyclic scaffolds combining phosphonates, nitriles, aldehydes, and isocyanates is described. The optimization of the reaction, synthesis of a small library of different triazinane diones, as well as alternative routes toward the triazinane dione scaffold are discussed. © 2008 American Chemical Society.

AB - (Chemical Equation Presented) An efficient, one-pot synthetic protocol toward triazinane diones, a rather unexplored class of heterocyclic scaffolds combining phosphonates, nitriles, aldehydes, and isocyanates is described. The optimization of the reaction, synthesis of a small library of different triazinane diones, as well as alternative routes toward the triazinane dione scaffold are discussed. © 2008 American Chemical Society.

U2 - 10.1021/jo701973d

DO - 10.1021/jo701973d

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VL - 73

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EP - 722

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

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Groenendaal B, Vugts DJ, Schmitz RF, de Kanter FJJ, Ruijter E, Groen MB et al. A multicomponent synthesis of triazinane diones. Journal of Organic Chemistry. 2008;73(2):719-22. https://doi.org/10.1021/jo701973d