A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

J.A. Langendijk; P.A.H. Doornaert; D.H.F. Rietveld; I.M. de Leeuw; C.R. Leemans; B.J. Slotman

doi:10.1016/j.radonc.2008.12.017

A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

J.A. Langendijk, P.A.H. Doornaert, D.H.F. Rietveld, I.M. de Leeuw, C.R. Leemans, B.J. Slotman

Clinical Psychology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Introduction: Recently, we found that swallowing dysfunction after curative (chemo) radiation (CH) RT has a strong negative impact on health-related quality of life (HRQoL), even more than xerostomia. The purpose of this study was to design a predictive model for swallowing dysfunction after curative radiotherapy or chemoradiation. Materials and methods: A prospective study was performed including 529 patients with head and neck squamous cell carcinoma (HNSCC) treated with curative (CH) RT. In all patients, acute and late radiation-induced morbidity (RTOG Acute and Late Morbidity Scoring System) was scored prospectively. To design the model univariate and multivariate logistic regression analyses were carried out with grade 2 or higher RTOG swallowing dysfunction at 6 months as the primary (SWALL

Original language	English
Pages (from-to)	189-195
Number of pages	7
Journal	Radiotherapy and Oncology
Volume	90
Issue number	2
DOIs	https://doi.org/10.1016/j.radonc.2008.12.017
Publication status	Published - 2009

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title = "A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.",

abstract = "Introduction: Recently, we found that swallowing dysfunction after curative (chemo) radiation (CH) RT has a strong negative impact on health-related quality of life (HRQoL), even more than xerostomia. The purpose of this study was to design a predictive model for swallowing dysfunction after curative radiotherapy or chemoradiation. Materials and methods: A prospective study was performed including 529 patients with head and neck squamous cell carcinoma (HNSCC) treated with curative (CH) RT. In all patients, acute and late radiation-induced morbidity (RTOG Acute and Late Morbidity Scoring System) was scored prospectively. To design the model univariate and multivariate logistic regression analyses were carried out with grade 2 or higher RTOG swallowing dysfunction at 6 months as the primary (SWALL",

author = "J.A. Langendijk and P.A.H. Doornaert and D.H.F. Rietveld and {de Leeuw}, I.M. and C.R. Leemans and B.J. Slotman",

year = "2009",

doi = "10.1016/j.radonc.2008.12.017",

language = "English",

volume = "90",

pages = "189--195",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

AU - Langendijk, J.A.

AU - Doornaert, P.A.H.

AU - Rietveld, D.H.F.

AU - de Leeuw, I.M.

AU - Leemans, C.R.

AU - Slotman, B.J.

PY - 2009

Y1 - 2009

N2 - Introduction: Recently, we found that swallowing dysfunction after curative (chemo) radiation (CH) RT has a strong negative impact on health-related quality of life (HRQoL), even more than xerostomia. The purpose of this study was to design a predictive model for swallowing dysfunction after curative radiotherapy or chemoradiation. Materials and methods: A prospective study was performed including 529 patients with head and neck squamous cell carcinoma (HNSCC) treated with curative (CH) RT. In all patients, acute and late radiation-induced morbidity (RTOG Acute and Late Morbidity Scoring System) was scored prospectively. To design the model univariate and multivariate logistic regression analyses were carried out with grade 2 or higher RTOG swallowing dysfunction at 6 months as the primary (SWALL

AB - Introduction: Recently, we found that swallowing dysfunction after curative (chemo) radiation (CH) RT has a strong negative impact on health-related quality of life (HRQoL), even more than xerostomia. The purpose of this study was to design a predictive model for swallowing dysfunction after curative radiotherapy or chemoradiation. Materials and methods: A prospective study was performed including 529 patients with head and neck squamous cell carcinoma (HNSCC) treated with curative (CH) RT. In all patients, acute and late radiation-induced morbidity (RTOG Acute and Late Morbidity Scoring System) was scored prospectively. To design the model univariate and multivariate logistic regression analyses were carried out with grade 2 or higher RTOG swallowing dysfunction at 6 months as the primary (SWALL

U2 - 10.1016/j.radonc.2008.12.017

DO - 10.1016/j.radonc.2008.12.017

M3 - Article

SN - 0167-8140

VL - 90

SP - 189

EP - 195

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

IS - 2

ER -

A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

Abstract

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