A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

J.A. Langendijk; P.A.H. Doornaert; D.H.F. Rietveld; I.M. de Leeuw; C.R. Leemans; B.J. Slotman

doi:10.1016/j.radonc.2008.12.017

A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

J.A. Langendijk
, P.A.H. Doornaert
, D.H.F. Rietveld
, I.M. de Leeuw
, C.R. Leemans
, B.J. Slotman

Clinical Psychology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Introduction: Recently, we found that swallowing dysfunction after curative (chemo) radiation (CH) RT has a strong negative impact on health-related quality of life (HRQoL), even more than xerostomia. The purpose of this study was to design a predictive model for swallowing dysfunction after curative radiotherapy or chemoradiation. Materials and methods: A prospective study was performed including 529 patients with head and neck squamous cell carcinoma (HNSCC) treated with curative (CH) RT. In all patients, acute and late radiation-induced morbidity (RTOG Acute and Late Morbidity Scoring System) was scored prospectively. To design the model univariate and multivariate logistic regression analyses were carried out with grade 2 or higher RTOG swallowing dysfunction at 6 months as the primary (SWALL

Original language	English
Pages (from-to)	189-195
Number of pages	7
Journal	Radiotherapy and Oncology
Volume	90
Issue number	2
DOIs	https://doi.org/10.1016/j.radonc.2008.12.017
Publication status	Published - 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.radonc.2008.12.017

http://www.sciencedirect.com/science/article/pii/S016781400900005X

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title = "A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.",

abstract = "Introduction: Recently, we found that swallowing dysfunction after curative (chemo) radiation (CH) RT has a strong negative impact on health-related quality of life (HRQoL), even more than xerostomia. The purpose of this study was to design a predictive model for swallowing dysfunction after curative radiotherapy or chemoradiation. Materials and methods: A prospective study was performed including 529 patients with head and neck squamous cell carcinoma (HNSCC) treated with curative (CH) RT. In all patients, acute and late radiation-induced morbidity (RTOG Acute and Late Morbidity Scoring System) was scored prospectively. To design the model univariate and multivariate logistic regression analyses were carried out with grade 2 or higher RTOG swallowing dysfunction at 6 months as the primary (SWALL",

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language = "English",

volume = "90",

pages = "189--195",

journal = "Radiotherapy and Oncology",

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TY - JOUR

T1 - A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

AU - Langendijk, J.A.

AU - Doornaert, P.A.H.

AU - Rietveld, D.H.F.

AU - de Leeuw, I.M.

AU - Leemans, C.R.

AU - Slotman, B.J.

PY - 2009

Y1 - 2009

N2 - Introduction: Recently, we found that swallowing dysfunction after curative (chemo) radiation (CH) RT has a strong negative impact on health-related quality of life (HRQoL), even more than xerostomia. The purpose of this study was to design a predictive model for swallowing dysfunction after curative radiotherapy or chemoradiation. Materials and methods: A prospective study was performed including 529 patients with head and neck squamous cell carcinoma (HNSCC) treated with curative (CH) RT. In all patients, acute and late radiation-induced morbidity (RTOG Acute and Late Morbidity Scoring System) was scored prospectively. To design the model univariate and multivariate logistic regression analyses were carried out with grade 2 or higher RTOG swallowing dysfunction at 6 months as the primary (SWALL

AB - Introduction: Recently, we found that swallowing dysfunction after curative (chemo) radiation (CH) RT has a strong negative impact on health-related quality of life (HRQoL), even more than xerostomia. The purpose of this study was to design a predictive model for swallowing dysfunction after curative radiotherapy or chemoradiation. Materials and methods: A prospective study was performed including 529 patients with head and neck squamous cell carcinoma (HNSCC) treated with curative (CH) RT. In all patients, acute and late radiation-induced morbidity (RTOG Acute and Late Morbidity Scoring System) was scored prospectively. To design the model univariate and multivariate logistic regression analyses were carried out with grade 2 or higher RTOG swallowing dysfunction at 6 months as the primary (SWALL

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DO - 10.1016/j.radonc.2008.12.017

M3 - Article

SN - 0167-8140

VL - 90

SP - 189

EP - 195

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

IS - 2

ER -

A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

Abstract

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