In this study, we show the relationship between sea-level anomalies (SLA) and upper-ocean parameters in the Equatorial Indian Ocean (EIO). This work also focuses on the variability of SLA obtained from satellite altimeter data in different spatial and temporal scales and its relationship with computed ocean heat content (OHC), dynamic height (DH), and thermocline depth (20 °C isotherm: D20) during 1993–2015. SLA showed low Pearson’s correlation coefficient (CC) with upper-ocean parameters over central EIO resembling a “Monopole” pattern. The Array for Real-time Geostrophic Oceanography (ARGO) in situ profile data in the central EIO also confirmed this. SLA over this monopole showed low correlations with all parameters as compared with eastern and western EIO. These findings show a clear signature of a persisting sea-level monopole in the central EIO. Oscillating SLA over western and eastern EIO during summer and winter monsoon months is found to be responsible for locking this monopole in the central EIO. Both SLA and OHC increased in EIO during 2006–2015 compared with 1993–2005. The month of January showed different east–west trends at different times. This trend during 1993–2015 is neutral, but it shifted from negative during 1993–2005 to positive during 2006–2015.