A walk on the dark side: TMS over the right inferior frontal gyrus (rIFG) disrupts behavioral responses to infant stimuli

Pietro De Carli, Marian J. Bakermans-Kranenburg, Laura Parolin, Carlotta Lega, Beatrice Zanardo, Zaira Cattaneo, Madelon M.E. Riem

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Infant signals, including infant sounds and facial expressions, play a critical role in eliciting parental proximity and care. Processing of infant signals in the adulthood brain is likely to recruit emotional empathy neural circuits, including the inferior frontal gyrus (IFG). Here, we used transcranial magnetic stimulation (TMS) to test the role of right IFG (rIFG) in behavioral responses to infant signals. Specifically, a group of nulliparous women were asked to perform a handgrip dynamometer task and an Approach-Avoidance Task (AAT) after receiving TMS over the right IFG or over a control site (vertex). Suppressing activity in the rIFG affected the modulation of handgrip force in response to infant crying. Moreover, the AAT showed that participants tend to avoid the sad infant face after Vertex stimulation, and this bias was counteracted by rIFG stimulation. Our results suggest a causal role of rIFG in sensitive responding towards sad infants and point to the rIFG as a critical node in the neural network underlying the innate releasing mechanism for feelings of love, affection and caring of sad infants.

LanguageEnglish
Pages1-8
Number of pages8
JournalSocial Neuroscience
DOIs
Publication statusE-pub ahead of print - 6 Feb 2019

Fingerprint

Transcranial Magnetic Stimulation
behavioral response
Prefrontal Cortex
infant
stimulus
Crying
Facial Expression
facial expression
Love
sympathy
empathy
neural network
adulthood
brain
love
Emotions
Brain
trend

Keywords

  • Infant cry
  • infant faces
  • repetitive transcranial magnetic stimulation (rTMS)
  • right inferior frontal gyrus (rIFG)

Cite this

De Carli, Pietro ; Bakermans-Kranenburg, Marian J. ; Parolin, Laura ; Lega, Carlotta ; Zanardo, Beatrice ; Cattaneo, Zaira ; Riem, Madelon M.E. / A walk on the dark side : TMS over the right inferior frontal gyrus (rIFG) disrupts behavioral responses to infant stimuli. In: Social Neuroscience. 2019 ; pp. 1-8.
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A walk on the dark side : TMS over the right inferior frontal gyrus (rIFG) disrupts behavioral responses to infant stimuli. / De Carli, Pietro; Bakermans-Kranenburg, Marian J.; Parolin, Laura; Lega, Carlotta; Zanardo, Beatrice; Cattaneo, Zaira; Riem, Madelon M.E.

In: Social Neuroscience, 06.02.2019, p. 1-8.

Research output: Contribution to JournalArticleAcademicpeer-review

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